Influence of compression forces on tablets disintegration by AC Biosusceptometry

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 69, Issue 1, 2008, Pages 372-379

  Corá, Luciana A ^a   Fonseca, Paulo R ^a   Américo, Madileine F ^b   Oliveira, Ricardo B ^b   Baffa, Oswaldo ^b   Miranda, José Ricardo A ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

AC Biosusceptometry; Compression force; Disintegration; Disintegration force; Magnetic tablets; Water uptake

Indexed keywords

ALTERNATE CURRENT BIOSUSCEPTOMETRY; ANALYTIC METHOD; ARTICLE; BIOMAGNETISM; COMPRESSION; DRUG INDUSTRY; DRUG MANUFACTURE; KINETICS; PHYSICAL PARAMETERS; PHYSICAL PHENOMENA; QUALITY CONTROL; TABLET; WATER TRANSPORT;

CHEMISTRY, PHARMACEUTICAL; CHEMISTRY, PHYSICAL; COMPRESSIVE STRENGTH; DRUG COMPOUNDING; DRUG STABILITY; EQUIPMENT DESIGN; KINETICS; MAGNETICS; MECHANICS; SOLUBILITY; STRESS, MECHANICAL; TABLETS; TABLETS, ENTERIC-COATED; TIME FACTORS; WATER;

EID: 41549096786     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2007.11.005     Document Type: Article

References (25)

1. Sastry S.V., Nyshadham J.R., and Fix J.A. Recent technological advances in oral drug delivery. Pharm. Sci. Technol. Today 3 (2000) 138-145
2. Jivraj M., Martini L.G., and Thomson C.M. An overview of the different excipients useful for the direct compression of tablets. Pharm. Sci. Technol. Today 3 (2000) 58-63
3. Melia C.D., and Davis S.S. Review article: mechanisms of drug release from tablets and capsules. I: Disintegration. Aliment. Pharmacol. Ther. 3 (1989) 223-232
4. Zhao N., and Augsburger L.L. Functionality comparison of 3 classes of superdisintegrants in promoting aspirin tablet disintegration and dissolution. AAPS Pharm. Sci. Tech. 6 (2005) 634-640
5. Lin K.-H., Lin S.-Y., and Li M.-J. Compression forces and amount of outer coating layer affecting the time-controlled disintegration of the compression-coated tablets prepared by direct compression with micronized ethylcellulose. J. Pharm. Sci. 90 (2001) 2005-2009
6. Lowenthal W. Disintegration of tablets. J. Pharm. Sci. 61 (1972) 1695-1711
7. Ibrahim H.G. Observations on the dissolution behavior of a tablet formulation: effect of compression forces. J. Pharm. Sci. 74 (1985) 575-577
8. Riippi M., Antikainen O., Niskanen T., and Yliruusi J. The effect of compression force on surface structure, crushing strength, friability and disintegration time of erythromycin acistrate tablets. Eur. J. Pharm. Biopharm. 46 (1998) 339-345
9. Colombo P., Caramella C., Conte U., La Manna A., Guyot-Hermann A.M., and Ringard J. Disintegrating force and tablet properties. Drug Dev. Ind. Pharm. 7 (1981) 135-153
10. Colombo P., Conte U., Caramella C., Geddo M., and La Manna A. Disintegration force as a new formulation parameter. J. Pharm. Sci. 73 (1984) 701-705
11. Caramella C., Colombo P., Conte U., Ferrari F., Gazzaniga A., La Manna A., and Peppas N.A. A physical analysis of the phenomenon of tablet disintegration. Int. J. Pharm. 44 (1988) 177-186
12. van Kamp H.V., Bolhuis G.K., de Boer A.H., Lerk C.F., and Lie-A-Huen L. The role of water uptake on tablet disintegration. Pharm. Acta Helv. 61 (1986) 22-29
13. Peppas N.A., and Colombo P. Development of disintegration forces during water penetration in porous pharmaceutical systems. J. Control. Release 10 (1989) 245-250
14. Catellani P.L., Predella P., Bellotti A., and Colombo P. Tablet water uptake and disintegration force measurements. Int. J. Pharm. 51 (1989) 63-66
15. Pena Romero A., Caramella C., Ronchi M., Ferrari F., and Chulia D. Water uptake and force development in an optimized prolonged release formulation. Int. J. Pharm. 73 (1991) 239-248
16. Corá L.A., Américo M.F., Oliveira R.B., Baffa O., Moraes R., Romeiro F.G., and Miranda J.R.A. Disintegration of magnetic tablets in human stomach evaluated by alternate current Biosusceptometry. Eur. J. Pharm. Biopharm. 56 (2003) 413-420
17. Corá L.A., Andreis U., Romeiro F.G., Américo M.F., Oliveira R.B., Baffa O., and Miranda J.R.A. Magnetic images of the disintegration process of tablets in the human stomach by AC Biosusceptometry. Phys. Med. Biol. 50 (2005) 5523-5534
18. Corá L.A., Romeiro F.G., Stelzer M., Américo M.F., Oliveira R.B., Baffa O., and Miranda J.R.A. AC Biosusceptometry in the study of drug delivery. Adv. Drug Deliv. Rev. 57 (2005) 1223-1241
19. Corá L.A., Romeiro F.G., Paixão F.C., Américo M.F., Oliveira R.B., Baffa O., and Miranda J.R.A. Enteric coated magnetic HPMC capsules evaluated in the human gastrointestinal tract by AC Biosusceptometry. Pharm. Res. 23 (2006) 1809-1816
20. Corá L.A., Romeiro F.G., Américo M.F., Oliveira R.B., Baffa O., Stelzer M., and Miranda J.R.A. Gastrointestinal transit and disintegration of enteric coated magnetic tablets assessed by AC Biosusceptometry. Eur. J. Pharm. Sci. 27 (2006) 1-8
21. Langenbucher F. Linearization of dissolution rate curves by the Weibull distribution. J. Pharm. Pharmacol. 24 (1972) 979-981
22. Lowenthal W. Mechanism of action of tablet disintegrants. Pharm. Acta Helv. 48 (1973) 589-609
23. Caramella C., Ferrari F., Bonferoni M.C., and Ronchi M. Disintegrants in solid dosage forms. Drug Dev. Ind. Pharm. 16 (1990) 2561-2577
24. Massimo G., Santi P., Colombo G., Nicoli S., Zani F., Colombo P., and Bettini R. The suitability of disintegrating force kinetics for studying the effect of manufacturing parameters on spironolactone tablet properties. AAPS Pharm. Sci. Tech. 4 (2003) 1-7
25. Weitschies W., Hartmann V., Grützmann R., and Breitkreutz J. Determination of the disintegration behavior of magnetically marked tablets. Eur. J. Pharm. Biopharm. 52 (2001) 221-226