Endosomal proteolysis of diphtheria toxin without toxin translocation into the cytosol of rat liver in vivo

FEBS Journal

Volumn 275, Issue 8, 2008, Pages 1708-1722

  El Hage, Tatiana ^a,b   Decottignies, Paulette ^b,c   Authier, François ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c CNRS   (France)

Author keywords

Cathepsin D; Diphtheria toxin; Endosome; Furin; Translocation

Indexed keywords

ASPARTIC PROTEINASE; CATHEPSIN D; DIPHTHERIA TOXIN; FURIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ENDOCYTOSIS; ENDOSOME; ENZYME ACTIVITY; HOST RESISTANCE; INTERNALIZATION; INTRACELLULAR TRANSPORT; LIVER CYTOSOL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; TOXICOKINETICS; TOXIN ANALYSIS; TOXIN STRUCTURE;

ANIMALS; CATALYSIS; CATHEPSINS; CYTOSOL; DIPHTHERIA TOXIN; ENDOSOMES; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; LIVER; LYSOSOMES; MALE; MUTATION; PROTEIN TRANSPORT; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 41549085632     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2008.06326.x     Document Type: Article

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