Cyclic AMP-protein kinase A and Snf1 signaling mechanisms underlie the superior potency of sucrose for induction of filamentation in Saccharomyces cerevisiae

Eukaryotic Cell

Volumn 7, Issue 2, 2008, Pages 286-293

  Van De Velde, Sam ^a,b   Thevelein, Johan M ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SACCHAROMYCES CEREVISIAE;

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; G PROTEIN COUPLED RECEPTOR; GPR1 PROTEIN, S CEREVISIAE; MEMBRANE PROTEIN; MUC1 PROTEIN, S CEREVISIAE; PROTEIN SERINE THREONINE KINASE; SACCHAROMYCES CEREVISIAE PROTEIN; SNF1 RELATED PROTEIN KINASES; SNF1-RELATED PROTEIN KINASES; SUCROSE; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION;

CELL DIFFERENTIATION; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; MEMBRANE PROTEINS; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, G-PROTEIN-COUPLED; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION; SUCROSE;

EID: 41449108897     PISSN: 15359778     EISSN: None     Source Type: Journal    
DOI: 10.1128/EC.00276-07     Document Type: Article

References (22)

1. Amberg, D. C., D. J. Burke, and J. N. Strathern. 2005. Methods in yeast genetics: a Cold Spring Harbor Laboratory course manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
2. Ashrafi, K., S. S. Lin, J. K. Manchester, and J. I. Gordon. 2000. Sip2p and its partner snf1p kinase affect aging in S. cerevisiae. Genes Dev. 14:1872-1885.
3. Boeckstaens, M., B. Andre, and A. M. Marini. 2007. The yeast ammonium transport protein Mep2 and its positive regulator, the Npr1 kinase, play an important role in normal and pseudohyphal growth on various nitrogen media through retrieval of excreted ammonium. Mol. Microbiol. 64:534-546.
4. Chen, H., and G. R. Fink. 2006. Feedback control of morphogenesis in fungi by aromatic alcohols. Genes Dev. 20:1150-1161.
5. Gancedo, J. M. 2001. Control of pseudohyphae formation in Saccharomyces cerevisiae. FEMS Microbiol. Rev. 25:107-123.
6. Gietz, R. D., and A. Sugino. 1988. New yeast Escherichia coli shuttle vectors constructed with in vitro mutagenized genes lacking six-base pair restriction sites. Gene 74:527-534.
7. Gimeno, C. J., P. O. Ljungdahl, C. A. Styles, and G. R. Fink. 1992. Unipolar cell divisions in the yeast S. cerevisiae lead to filamentous growth: regulation by starvation and RAS. Cell 68:1077-1090.
8. Halme, A., S. Bumgarner, C. Styles, and G. R. Fink. 2004. Genetic and epigenetic regulation of the FLO gene family generates cell-surface variation in yeast. Cell 116:405-415.
9. Jiang, R., and M. Carlson. 1996. Glucose regulates protein interactions within the yeast SNF1 protein kinase complex. Genes Dev. 10:3105-3115.
10. Kraakman, L., K. Lemaire, P. Ma, A. W. R. H. Teunissen, M. C. V. Donaton, P. Van Dijck, J. Winderickx, J. H. de Winde, and J. M. Thevelein. 1999. A Saccharomyces cerevisiae G-protein coupled receptor, Gpr1, is specifically required for glucose activation of the cAMP pathway during the transition to growth on glucose. Mol. Microbiol. 32:1002-1012.
11. Kuchin, S., V. K. Vyas, and M. Carlson. 2002. Snf1 protein kinase and the repressors Nrg1 and Nrg2 regulate FLO11, haploid invasive growth, and diploid pseudohyphal differentiation. Mol. Cell. Biol. 22:3994-4000.
12. Lemaire, K., S. Van de Velde, P. Van Dijck, and J. M. Thevelein. 2004. Glucose and sucrose act as agonist and mannose as antagonist ligands of the G-protein coupled receptor Gpr1 in the yeast Saccharomyces cerevisiae. Mol. Cell 16:293-299.
13. Lin, S. S., J. K. Manchester, and J. I. Gordon. 2003. Sip2, an N-myristoylated beta subunit of Snf1 kinase, regulates aging in Saccharomyces cerevisiae by affecting cellular histone kinase activity, recombination at rDNA loci, and silencing. J. Biol. Chem. 278:13390-13397.
14. Lo, W. S., and A. M. Dranginis. 1996. FLO11, a yeast gene related to the STA genes, encodes a novel cell surface flocculin. J. Bacteriol. 178:7144-7151.
15. Lo, W. S., L. Duggan, N. C. Emre, R. Belotserkovskya, W. S. Lane, R. Shiekhattar, and S. L. Berger. 2001. Snf1 - a histone kinase that works in concert with the histone acetyltransferase Gcn5 to regulate transcription. Science. 293:1142-1146.
16. Lorenz, M. C., and J. Heitman. 1997. Yeast pseudohyphal growth is regulated by GPA2, a G protein α homolog. EMBO J. 16:7008-7018.
17. Lorenz, M. C., and J. Heitman. 1998. The MEP2 ammonium permease regulates pseudohyphal differentiation in Saccharomyces cerevisiae. EMBO J. 17:1236-1247.
18. Lorenz, M. C., X. Pan, T. Harashima, M. E. Cardenas, Y. Xue, J. P. Hirsch, and J. Heitman. 2000. The G protein-coupled receptor Gpr1 is a nutrient sensor that regulates pseudohyphal differentiation in Saccharomyces cerevisiae. Genetics 154:609-622.
19. Orlova, M., E. Kanter, D. Krakovich, and S. Kuchin. 2006. Nitrogen availability and TOR regulate the Snf1 protein kinase in Saccharomyces cerevisiae. Eukaryot. Cell. 5:1831-1837.
20. Van Nuland, A., P. Vandormael, M. Donaton, M. Alenquer, A. Lourenco, E. Quintino, M. Versele, and J. M. Thevelein. 2006. Ammonium permease-based sensing mechanism for rapid ammonium activation of the protein kinase A pathway in yeast. Mol. Microbiol. 59:1485-1505.
21. Wang, Y., M. Pierce, L. Schneper, C. G. Guldal, X. Zhang, S. Tavazoie, and J. R. Broach. 2004. Ras and Gpa2 mediate one branch of a redundant glucose signaling pathway in yeast. PLoS Biol. 2:e128.
22. Zimmermann, F. K., and I. Scheel. 1977. Mutants of Saccharomyces cerevisiae resistant to carbon catabolite repression. Mol. Gen. Genet. 154: 75-82.