Expression of the p63 and Notch signaling systems in rat testes during postnatal development: Comparison with their expression levels in the epididymis and vas deferens

Journal of Andrology

Volumn 25, Issue 5, 2004, Pages 692-698

  Hayashi, Tetsuo ^a   Yoshinaga, Atsushi ^a   Ohno, Rena ^a   Ishii, Nobuyuki ^a   Kamata, Shigeyoshi ^a   Yamada, Takumi ^a  

^a SAITAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Differentiation; p53; Spermatogenesis

Indexed keywords

ISOPROTEIN; LIGAND; NOTCH RECEPTOR; NOTCH1 RECEPTOR; PROTEIN P53; PROTEIN P63;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; BASAL CELL; BASEMENT MEMBRANE; CELL DIFFERENTIATION; CELL POPULATION; CONTROLLED STUDY; EPIDIDYMIS; GAMETOGENESIS; GERM CELL; IMMUNOHISTOCHEMISTRY; MALE; NEWBORN; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; SEMINIFEROUS TUBULE EPITHELIUM; SIGNAL TRANSDUCTION; SPERMATOGENESIS; SPERMATOZOON; SPERMATOZOON MIGRATION; VAS DEFERENS;

EID: 4143117983     PISSN: 01963635     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1939-4640.2004.tb02843.x     Document Type: Article

References (22)

1. Atanassova N, McKinnell C, Williams K, Turner KJ, Fisher JS, Saunders PTK, Millar MR, Sharpe RM. Age-, cell- and region-specific immunoexpression of estrogen receptor a (but not estrogen receptor b) during postnatal development of epididymis and vas deferens of rat and disruption of this pattern by neonatal treatment with diethylstilbestrol. Endocrinology. 2001;142:874-886.
2. Clermont Y, Huckins C. Microscopic anatomy of the sex cords and seminiferous tubules in growing and adult male albino rats. Am J Anat. 1961;108:79-97.
3. Cooper TG. Interactions between epididymal secretions and spermatozoa. J Reprod Fertil Suppl. 1998;53:119-136.
4. de Kretser DM, Kerr JB. The cytology of the testis. In: Knobil E, Neill JD, eds. The Physiology of Reproduction, Vol 1, 2nd ed. New York, NY: Raven Press; 1994:1177-1290.
5. de Kretser DM, Temple-Smith PD, Kerr JB. Anatomical and functional aspects of the male reproductive organs. In: Bandhauer K, Frick J, eds. Handbook of Urology. Vol XVI. Disturbances in Male Fertility. Berlin, Germany: Springer-Verlag; 1982:1-131.
6. Hayashi T, Kageyama Y, Ishizaka K, Kihara K, Oshima H. Sexual dimorphism in the regulation of meiotic process in the rabbit. Biol Reprod. 2000;62:1722-1727.
7. Hayashi T, Kageyama Y, Ishizaka K, Kihara K, Oshima H. Involvement of apoptosis in the control of Sertoli and pre-meiotic germ cell numbers in the developing rabbit testis. Andrologia. 2002;34:34-40.
8. Hayashi T, Kageyama Y, Ishizaka K, Xia GB, Kihara K, Oshima H. Requirement of Notch 1 and its ligand Jagged 2 expressions for spermatogenesis in rat and human testes. J Androl. 2001;22:999-1011.
9. Hermo L, Oko R, Morales CR. Secretion and endocytosis in the male reproductive tract: a role in sperm maturation. Int Rev Cytol. 1994; 154:106-189.
10. Hinton BT, Palldino MA, Rudolph D, Labus JC. The epididymis as protector of maturing spermatozoa. Reprod Fertil Dev. 1995;7:731-745.
11. Holland MK, Nixon B. The specificity of epididymal secretory proteins. J Reprod Fertil Suppl. 1998;53:197-210.
12. Kirchhoff C. Gene expression in the epididymis. Int Rev Cytol. 1999;188: 133-202.
13. Mills A, Zheng B, Wang X, Vogel H, Roop D, Bradley A. p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature. 1999;398:708-713.
14. Osada M, Ohba M, Kawahara C, et al. Cloning and functional analysis of human p51, which structurally and functionally resembles p53. Nat Med. 1998;4:839-843.
15. Robaire B, Hermo L. Efferent duct, epididymis and vas deferens; structure, functions and their regulation. In: Knobil E, Neill JD, eds. The Physiology of Reproduction. Vol 1. New York, NY: Raven Press; 1988:999-1080.
16. Sasaki Y, Ishida S, Morimoto I, et al. The p53 family member genes are involved in the Notch signal pathway. J Biol Chem. 2002;227:719-724.
17. Turner TT, Miller DW. On the synthesis and secretion of rat seminiferous tubule proteins in vivo after ischemia and germ cell loss. Biol Reprod. 1997;57:1275-1284.
18. Turner TT, Riley TA, Mruk DD, Cheng CY. Obstruction of the vas deferens alters protein secretion by the rat caput epididymal epithelium in vivo. J Androl. 1999;20:289-297.
19. Wang T, Chen B, Yang Y, et al. Histologic and immunophenotypic classification of cervical carcinomas by expression of the p53 homologue p63: a study of 250 cases. Hum Pathol. 2001;32:479-486.
20. Yang A, Kaghad M, Wang Y, et al. p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol Cell. 1998;2:305-316.
21. Yang A, McKeon F. p63 and p73: p53 mimics, menaces and more. Nat Rev Mol Cell Biol. 2000;1:199-207.
22. Yang A, Schweitzer R, Sun D, et al. p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development. Nature. 1999;398:714-718.