CO-trapping site in heme oxygenase revealed by photolysis of its CO-bound heme complex: Mechanism of escaping from product inhibition

Journal of Molecular Biology

Volumn 341, Issue 1, 2004, Pages 7-13

  Sugishima, Masakazu ^a   Sakamoto, Hiroshi ^b   Noguchi, Masato ^b   Fukuyama, Keiichi ^a,c  

^a OSAKA UNIVERSITY   (Japan)

^b KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c RIKEN HARIMA INSTITUTE   (Japan)

Author keywords

CO heme HO, heme HO bound to carbon monoxide; cryo trapped structure; heme oxygenase; heme HO, HO in complex with heme; HO, heme oxygenase; hydrophobic cavity; photolysis of carbon monoxide; product inhibition; verdoheme HO, HO in complex with verdoheme

Indexed keywords

CARBON MONOXIDE; HEME; HEME OXYGENASE; IRON; XENON;

ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CRYSTAL STRUCTURE; DISSOCIATION; FOURIER ANALYSIS; HYDROPHOBICITY; ILLUMINATION; LASER; MOLECULAR MECHANICS; NONHUMAN; PHOTOLYSIS; PRIORITY JOURNAL; RAT; X RAY DIFFRACTION;

EID: 4143105792     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2004.05.048     Document Type: Article

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