Expression and phosphorylation of δ-CaM kinase II in cultured Alzheimer fibroblasts

Neurobiology of Aging

Volumn 25, Issue 9, 2004, Pages 1187-1196

  Cavazzin, Chiara ^a   Bonvicini, Cristian ^b   Nocera, Annachiara ^a   Racchi, Marco ^c   Kasahara, Jiro ^d   Tardito, Daniela ^a   Gennarelli, Massimo ^e   Govoni, Stefano ^c   Racagni, Giorgio ^a,b   Popoli, Maurizio ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b IRCCS ISTITUTO CENTRO SAN GIOVANNI DI DIO FATEBENEFRATELLI   (Italy)

^c UNIVERSITY OF PAVIA   (Italy)

^d TOHOKU UNIVERSITY   (Japan)

^e UNIVERSITY OF BRESCIA   (Italy)

Author keywords

Alzheimer; CaM kinase; Human fibroblast; Neuroplasticity; Protein phosphorylation; Signal transduction

Indexed keywords

PROTEIN KINASE (CALCIUM,CALMODULIN) II;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; AUTOPHOSPHORYLATION; CELL CYCLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; MALE; NERVE CELL PLASTICITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; STATISTICAL SIGNIFICANCE; WESTERN BLOTTING;

AGED; ALZHEIMER DISEASE; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM; CALCIUM SIGNALING; CALMODULIN; CELLS, CULTURED; COGNITION DISORDERS; FEMALE; FIBROBLASTS; HUMANS; ISOENZYMES; MALE; MIDDLE AGED; NEURONAL PLASTICITY; PHOSPHORYLATION; RNA, MESSENGER; SIGNAL TRANSDUCTION; THREONINE;

EID: 4143099053     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2003.12.003     Document Type: Article

References (40)

1. Bayer K.-U., De Koninck P., Leonard A.S., Hell J.W., Schulman H. Interaction with the NMDA receptor locks CaMKII in an active conformation. Nature. 411(6839):2001;801-805
2. 2+/calmodulin-dependent protein kinase IV. J. Biol. Chem. 269(22):1994;15520-15527
3. Ferrarese C., Begni B., Canevari C., Zoia C., Piolti R., Frigo M., et al. Glutamate uptake is decreased in platelets from Alzheimer's disease patients. Ann. Neurol. 47(5):2000;641-643
4. Frisoni G.B., Calabresi L., Geroldi C., Bianchetti A., D'Acquarica A.L., Govoni S., et al. Apolipoprotein E epsilon 4 allele in Alzheimer's disease and vascular dementia. Dementia. 5(5):1994;240-242
5. 2+/calmodulin-dependent protein kinase II in cerebellar granule cells. J. Biol. Chem. 264(36):1989;21830-21836
6. Gasparini L., Racchi M., Binetti G., Trabucchi M., Solerte S.B., Alkon D., et al. Peripheral markers in testing pathophysiological hypotheses and diagnosing Alzheimer's disease. FASEB J. 12(1):1998;17-34
7. Gibson E.G., Zhang H., Xu H., Park L.C., Jeitner T.M. Oxidative stress increases internal calcium stores and reduces a key mitochondrial enzyme. Bioch. Biophys. Acta. 1586(2):2002;177-189
8. 286 of the alpha calcium-calmodulin kinase II in LTP and learning. Science. 279(5352):1998;870-873
9. Govoni S., Bergamaschi S., Racchi M., Battaini F., Binetti G., et al. Cytosol protein kinase C downregulation in fibroblasts from Alzheimer's disease patients. Neurology. 43(12):1993;2581-2586
10. Harkany T., Abraham I., Timmerman W., Laskay G., Toth B., Sasvari M., et al. β-Amyloid neurotoxicity is mediated by a glutamate-triggered excitotoxic cascade in rat nucleus basalis. Eur. J. Neurosci. 12(8):2000;2735-2745
11. Herrup K., Yang Y. Pictures in molecular medicine contemplating Alzheimer's disease as cancer: a loss of cell-cycle control. Trends. Mol. Med. 7(11):2001;527
12. 2+/calmodulin-dependent protein kinase II: the role of structure and autoregulation in cellular function. Annu. Rev. Biochem. 71:2002;473-510
13. Ishida A., Kameshita I., Okuno S., Kitani T., Fujisawa H. A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II. Biochem. Biophys. Res. Comm. 212(3):1995;806-812
14. 2+ mobilization is altered in fibroblasts from patients with Alzheimer's disease. Proc. Natl. Acad. Sci. USA. 91(2):1994;534-538
15. Mah V.H., Eskin T.A., Kazee A.M., Lapham L., Higgins G.A. In situ hybridization of calcium/calmodulin dependent protein kinase II and tau mRNAs: species differences and relative preservation in Alzheimer's disease. Brain. Res. Mol. Brain Res. 12(1-3):1992;85-94
16. 2+ homeostasis and cell death. J. Neurosci. 15(9):1995;6239-6249
17. Masliah E., Alford M., DeTeresa R., Mallory M., Hansen L. Deficient glutamate transport is associated with neurodegeneration in Alzheimer's disease. Ann. Neurol. 40(5):1996;759-766
18. Mattson M.P., Chan S.L. Dysregulation in cellular calcium homeostasis in Alzheimer disease neuronal plasticity and neurodegenerative disorders. J. Mol. Neurosci. 17(2):2001;205-224
19. 2+/calmodulin-dependent protein kinase in cultures of postnatal rat hippocampal slices. Proc. Natl. Acad. Sci. USA. 88(11):1991;4756-4760
20. kip1 with Cdk2 to cause G1 arrest in NIH 3T3 cells. Exp. Cell. Res. 240(2):1998;218-227
21. Murphy T.H., Blatte L.A., Bhat R.V., Fiore R.S., Wier W.G., Baraban J.M. Differential regulation of calcium/calmodulin-dependent protein kinase II and p42 MAP kinase activity by synaptic transmission. J. Neurosci. 14(3 Pt 1):1994;1320-1331
22. Murray K.D., Gall C.M., Jones E.G., Isackson P.J. Differential regulation of brain-derived neurotrophic factor and type II calcium/calmodulin-dependent protein kinase messenger RNA expression in Alzheimer's disease. Neuroscience. 60(1):1994;37-48
23. Nagy Z., Combrinck M., Budge M., McShane R. Cell cycle kinesis in lymphocytes in the diagnosis of Alzheimer's disease. Neurosci. Lett. 317(2):2002;81-84
24. 2+/calmodulin-dependent protein kinase I from bovine brain. J. Biol. Chem. 262(15):1987;7273-7281
25. 2+/calmodulin- dependent protein kinase. J. Biol. Chem. 268(8):1993;5471-5479
26. 2+/calmodulin-dependent kinase in intact hippocampal slices. Neuron. 6(6):1991;907-914
27. Palfrey H.C., Nairn A.C., Muldoon L.L., Villereal M.L. Rapid activation of calmodulin-dependent protein kinase III in mitogen-stimulated human fibroblasts. Correlation with intracellular Ca2+ transients. J. Biol. Chem. 262(20):1987;9785-9792
28. 2/M phase transition in HeLa cells. J. Biol. Chem. 274(12):1999;7958-7968
29. 2+/calmodulin protein kinase II in synaptic vesicles. FEBS Lett. 317(1/2):1993;85-88
30. 2+/calmodulin-dependent protein kinase II: autophosphorylation and activity increase in the hippocampus after long-term blockade of serotonin reuptake. Mol. Pharmacol. 48(4):1995;623-629
31. Popoli M., Gennarelli M., Racagni G. Modulation of synaptic plasticity by stress and antidepressants. Bip. Disorders. 4(3):2002;166-182
32. Shen K., Teruel M.N., Connor J.H., Shenolikar S., Meyer T. Molecular memory by reversible translocation of calcium/calmodulin dependent protein kinase II. Nat. Neurosci. 3(9):2000;881-886
33. Simonian N.A., Elvhage T., Czernik A.J., Greengard P., Hyman B.T. Calcium/calmodulin-dependent protein kinase II immunostaining is preserved in Alzheimer's disease hippocampal neurons. Brain. Res. 657(1/2):1994;294-299
34. Tobimatsu T., Fujisawa H. Tissue-specific expression of four types of rat calmodulin-dependent protein kinase II mRNAs. J. Biol. Chem. 264(30):1989;17907-17912
35. Tombes R.M., Mikkelsen R.B., Jarvis W.D., Grant S. Downregulation of δ CaM kinase II in human tumor cells. Biochem. Biophys. Acta. 1452(1):1999;1-11
36. Uberti D., Carsana T., Bernardi E., Rodella L., Grigolato P., Lanni C., et al. Selective impairment of p53-mediated cell death in fibroblasts from sporadic Alzheimer's disease patients. J. Cell. Sci. 115(Pt 15):2002;3131-3138
37. 2+/calmodulin-dependent protein kinase I in cultured rat hippocampal neurons. J. Neurochem. 82(3):2002;585-593
38. Verona M., Zanotti S., Schäfer T., Racagni G., Popoli M. Changes of synaptotagmin interaction with t-SNARE proteins in vitro after calcium/calmodulin-dependent phosphorylation. J. Neurochem. 74(1):2000;209-221
39. 2+-calmodulin-sensitive protein kinase type II is obligate for adipogenesis. J. Biol. Chem. 272(3):1997;1817-1821
40. Watt F. Nuclear microscope analysis in Alzheimer's and Parkinson's disease: a review. Cell. Mol. Biol. 42(1):1996;17-26