Genetics of asthma COPD: Similar results for different phenotypes

Chest

Volumn 126, Issue 2 SUPPL., 2004, Pages 105S-110S

  Meyers, Deborah A ^a   Larj, Michael J ^a   Lange, Leslie ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Asthma; COPD; FEV1; FVC

Indexed keywords

INTERLEUKIN 13;

ASTHMA; CHROMOSOME 2Q; CHRONIC OBSTRUCTIVE LUNG DISEASE; ENVIRONMENTAL FACTOR; FAMILY STUDY; GENETIC LINKAGE; GENETIC SCREENING; GENETIC SUSCEPTIBILITY; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; PASSIVE SMOKING; PHENOTYPE; PRIORITY JOURNAL; REVIEW; SMOKING;

EID: 4143083822     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.126.2_suppl_1.105S     Document Type: Article

References (29)

1. Howard TD, Meyers DA, Bleecker ER. Mapping susceptibility genes for allergic diseases. Chest 2003; 123:363S-368S
2. Pauwels RA, Buist AS, Calverley PMA, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) workshop summary. Am J Respir Crit Care Med 2001; 163:1256-1276
3. National Institutes of Health, National Heart, Lung, and Blood Institute. National Asthma Education and Prevention Program Expert Panel Report: guidelines for diagnosis and management of asthma; update on selected topics. Bethesda, MD: National Institutes of Health, 2002; NIH Publication No. 02-5075
4. 2-adrenergic receptor gene polymorphism and cigarette smoking. Am J Respir Crit Care Med 2001; 163:1404-1409
5. Holgate ST. Genetic and environmental interaction in allergy and asthma. J Allergy Clin Immunol 1999; 104:1139-1146
6. Weiss ST, Tager IB, Muñoz A, et al. The relationship of respiratory infections in early childhood to the occurrence of increased levels of bronchial responsiveness and atopy. Am Rev Respir Dis 1985; 131:573-578
7. Busse WW, Lemanske RF Jr, Dick EC. The relationship of viral respiratory infections and asthma. Chest 1992; 101(suppl):385S-388S
8. Silverman EK, Palmer LJ, Mosley JD, et al. Genomewide linkage analysis of quantitative spirometric phenotypes in severe early-onset chronic obstructive pulmonary disease. Am J Hum Genet 2002; 70:1229-1239
9. Xu J, Postma DS, Howard TD, et al. Major genes regulating total serum immunoglobulin E levels in families with asthma. Am J Hum Genet 2000; 67:1163-1173
10. Burrows B, Martinez FD, Cline MG, et al. The relationship between parental and children's serum IgE and asthma. Am J Respir Crit Care Med 1995; 152:1497-1500
11. Sherrill DL, Lebowitz MD, Halonen M, et al. Longitudinal evaluation of the association between pulmonary function and total serum IgE. Am J Respir Crit Care Med 1995; 152:98-102
12. Sears MR, Burrows B, Flannery EM, et al. Relation between airway responsiveness and serum IgE in children with asthma and in apparently normal children. N Engl J Med 1991; 325:1067-1071
13. Li YF, Gilliland FD, Berhane K, et al. Effects of in utero and environmental tobacco smoke exposure on lung function in boys and girls with and without asthma. Am J Respir Crit Care Med 2000; 162:2097-2104
14. Mannino DM, Moorman JE, Kingsley B, et al. Health effects related to environmental tobacco smoke exposure in children in the United States: data from the Third National Health and Nutrition Examination Survey. Arch Pediatr Adolesc Med 2001; 155:36-41
15. Lanphear BP, Aligne CA, Auinger P, et al. Residential exposures associated with asthma in US children. Pediatrics 2001; 107:505-511
16. Xu J, Meyers DA, Ober C, et al. Genomewide screen and identification of gene-gene interactions for asthma-susceptibility loci in three U. S. populations: collaborative study on the genetics of asthma Am J Hum Genet 2001; 68:1437-1446
17. Colilla S, Nicolae D, Pluzhnikov A, et al. Evidence for gene-environment interactions in a linkage study of asthma and smoking exposure. J Allergy Clin Immunol 2003; 111:840-846
18. Meyers DA, Bleecker ER, Jonepier J, et al. Genetic susceptibility to asthma and exposure to passive smoking. Eur Respir J 2003; 22:296S
19. Meyers DA, Postma DS, Panhuysen CI, et al. Evidence for a locus regulating total serum IgE levels mapping to chromosome 5. Genomics 1994; 23:464-470
20. Collaborative Study of the Genetics of Asthma (CSGA). A genome-wide search for asthma susceptibility loci in ethnically diverse populations. Nat Genet 1997; 15:389-397
21. Ober C, Cox NJ, Abney M, et al. Genome-wide search for asthma susceptibility loci in a founder population: the Collaborative Study on the Genetics of Asthma. Hum Mol Genet 1998; 7:1393-1398
22. Grunig G, Warnock M, Wakil AE, et al. Requirement for IL-13 independently of IL-4 in experimental asthma. Science 1998; 282:2261-2263
23. Zhu Z, Homer RJ, Wang Z, et al. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clin Invest 1999; 103:779-788
24. van der Pouw Kraan TCTM, van Veen A, Boeije LC, et al. An IL-13 promoter polymorphism associated with increased risk of allergic asthma. Genes Immun 1999; 1:61-65
25. Howard TD, Whittaker PA, Zaiman AL, et al. Identification and association of polymorphisms in the interleukin-13 gene with asthma and atopy in a Dutch population. Am J Respir Cell Mol Biol 2001; 25:377-384
26. van der Pouw Kraan TC, Kucukaycan M, Bakker AM, et al. Chronic obstructive pulmonary disease is associated with the -1055 IL-13 promoter polymorphism. Genes Immun 2002; 3:436-439
27. Keavney B, McKenzie C, Parish S, et al. Large-scale test of hypothesised associations between the angiotensin-converting-enzyme insertion/deletion polymorphism and myocardial infarction in about 5000 cases and 6000 controls: the International Studies of Infarct Survival (ISIS) Collaborators. Lancet 2000; 355:434-442
28. Ohar JA, Bleecker ER, Howard TD, et al. IL-13 polymorphism: predisposition towards COPD and asbestos-induced diseases [abstract]. Eur Respir J 2001; 18:P3588
29. Larj MJ, Bleecker ER. Therapeutic implications of the Dutch hypothesis: corticosteroids in asthma and COPD. Chest 2004 (in press)