Formulations of retinyl palmitate included in solid lipid nanoparticles: Characterization and influence on light-induced vitamin degradation

Journal of Drug Delivery Science and Technology

Volumn 18, Issue 2, 2008, Pages 119-124

  Carafa, M ^a   Marianecci, C ^b   Salvatorelli, M ^b   Di Marzio, L ^a   Cerreto, F ^b   Lucania, G ^b   Santucci, E ^b  

^a UNIVERSITY OF CHIETI   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

BHA; Isomerization; Normal phase HPLC; Retinyl palmitate; SLN

Indexed keywords

BUTYLATED HYDROXYANISOLE; CHOLIC ACID; DRUG CARRIER; GLYCEROL PALMITOSTEARATE; POLOXAMER; RETINOL PALMITATE; SOLID LIPID NANOPARTICLE; SURFACTANT; VITAMIN; WATER;

ARTICLE; DARKNESS; DEGRADATION; DRUG DEGRADATION; DRUG FORMULATION; DRUG RELEASE; DRUG STABILITY; FREEZE FRACTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIGHT; LIGHT SCATTERING; MELTING POINT; PHOTODEGRADATION; ULTRASOUND; ZETA POTENTIAL;

EID: 41349102979     PISSN: 17732247     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1773-2247(08)50019-0     Document Type: Article

References (42)

1. Müller R.H., Radtke M.,. Wissing S.A. - Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations. - Advanced Drug Delivery Reviews, 54, S131-S155, 2002.
2. Müller R.H,. Runge S.A. - Solid lipid nanoparticles (SLN) for controlled drug delivery. - In: Submicron Emulsions in Drug Targeting and Delivery, S. Benita Ed., Harwood Academic Publishers, Amsterdam, 1998, pp. 219-234.
3. Wissing S.A., Kayser O., Müller R.H. - Solid lipid nanoparticles for parenteral drug delivery. - Adv. Drug Deliv. Rev., 56, 1257-1272, 2004.
4. Yang S., Zhu J., Lu Y., Liang B., Yang C. - Body distribution of camptothecin solid lipid nanoparticles after oral administration. - Pharm. Res., 16, 751-757, 1999.
5. Jenning V., Thunemann A. F., Gohla S. H. - Characterisation of a novel solid lipid nanoparticle carrier system based on binary mixtures of liquid and solid lipids. - International Journal of Pharmaceutics, 199, 167-177, 2000.
6. Jenning, V., Gysler, A., Schafer-Korting, M., Gohla, S. H. - Vitamin A loaded solid lipid nanoparticles for topical use: occlusive properties and drug targeting to the upper skin. - European Journal of Pharmaceutics and Biopharmaceutics, 49, 211-218, 2000.
7. Souto E.B., Wissing S.A., Barbosa C.M., Müller R.H. - Development of a controlled release formulation based on SLN and NLC for topical clotrimazole delivery. - Int. J. Pharm., 278, 71-77, 2004.
8. Vyas S.P., Khar R.K. - Nanoparticles. - In: Targeted and Controlled Drug Delivery Novel Carrier Systems, Vyas S.P., Khar R.K., Eds., New Delhi, India: CBS Publishers, 2002, pp. 331-386.
9. nd ed., Raven Press, New York, 1994, p. 443.
10. Tsunoda T., Takabayashi K. - Stability of all-trans retinol in cream. - J. Soc. Cosmet. Chem., 46, 191-198, 1995.
11. Failloux N., Bonnet I., Baron M.H., Perrier E. - Quantitative analysis of vitamin A degradation by Raman spectroscopy. - Appl. Spectrosc., 57, 1117-1122, 2003.
12. Fu P.P., Xia Q., Yin J.J., Cherng S., Yan J., Mei N. - Photodecomposition of vitamin A and photobiological implications for the skin. - Photochemistry and Photobiology, 83, 409-424, 2007.
13. Yan J., Xia Q., Cherng S., Warner W.G., Howard P.C., Yu H. - Photo-induced DNA damage and photocytotoxicity of retinyl palmitate and its photodecomposition products. - Toxicology and Industrial Health, 21, 167-175, 2005.
14. Guaratini T., Gianeti M. D., Campos P.M.B.G.M. - Stability of cosmetic formulations containing esters of vitamins E and A: chemical and physical aspects. - International Journal of Pharmaceutics, 327, 12-16 2006.
15. Campos P.M.B.G.M., Gianeti M.D., Kanashiro A., Lucisano-Valim Y.M., Gaspar L.R. - In vitro antioxidant and in vivo photoprotective effects of an association of bioflavonoids with liposoluble vitamins. - Photochemistry and Photobiology, 82, 683-688, 2006.
16. Papageorgiou S., Varvaresou A., Hatziantoniou S., Tsirivas E., Demetzos C., Papaioannou G. - Photostability of retinoids: the influence of the container. - Review of Clinical Pharmacology and Pharmacokinetics, International Edition, 21, 49-53, 2007.
17. Jenning V., Schafer-Korting M., Ghola S. - Vitamin A-loaded solid lipid nanoparticles for topical use: drug release properties. - J. Control. Release, 66, 115-126, 2000.
18. Jee J.P., Lim S.J., Park J.S., Kim C.K. - Stabilization of all-trans retinol by loading lipophilic antioxidants in solid lipid nanoparticles. - European Journal of Pharmaceutics and Biopharmaceutics, 63, 134-139 2006.
19. Carlotti M.E., Sapino S., Trotta M., Battaglia L., Vione D., Pelizzetti E. - Photostability and stability over time of retinyl palmitate in an o/w emulsion and in SLN introduced in the emulsion. - Journal of Dispersion Science and Technology, 26, 125-138 2005.
20. Castro G.A., Oréfice R.L., Vilela J.M., Andrade M.S., Ferreira L.A. - Development of a new solid lipid nanoparticle formulation containing retinoic acid for topical treatment of acne. - J Microencapsul., 24, 395-407, 2007.
21. Jenning V., Gohla S.H. - Encapsulation of retinoids in solid lipid nanoparticles (SLN). - J. Microencapsulation, 18, 149-158 2001.
22. Lim S., Kim C. - Formulation parameters determining the physicochemical characteristics of solid lipid nanoparticles loaded with all-trans retinoic acid. - International Journal of Pharmaceutics, 243, 135-146, 2002.
23. Hu L., Tang X., Cui F. - Solid lipid nanoparticles (SLN) to improve oral bioavailability of poorly soluble drugs. - Journal of Pharmacy and Pharmacology, 56, 1527-1535, 2004.
24. Scalzo M., Santucci E., Cerreto F., Carafa M. - Model lipophilic formulations of retinyl palmitate: influence of conservative agents on light-induced degradation. - J. Pharm. Biomed. Anal., 34, 921-931, 2004.
25. Carafa M., Marianecci C., Codecà A., Squillaci P., , Scalzo M., Cerreto F., Santucci E. - Retinyl palpitate-loaded vesicles: influence on vitamin light-induced degradation. - J. Drug Del. Sci Tech., 16, 407-412, 2006.
26. Görner T., Gref R., Michenot D., Sommer F., Tran M.N., Dellacherie E. - Lidocaine-loaded biodegradable nanospheres I. Optimization of the drug incorporation into the polymer matrix. - J. Control. Release, 57, 259-268, 1999.
27. Giordano G.G., Refojo M.F., Arroyo M.H. - Sustained delivery of retinoic acid from microspheres of biodegradable polymer in PVR. - Invest. Ophthalmol. Vis. Sci., 34, 2743-2751, 1993.
28. Pople P.V., Singh K.K. - Development and evaluation of topical formulation containing solid lipid nanoparticles of Vitamin A. - AAPS PharmSciTech 7, Article 91, 2006 (http://www.aapspharmscitech.org).
29. Martínez-Sancho C., Herrero-Vanrell R., Negro S. - Vitamin A palmitate and aciclovir biodegradable microspheres for intraocular sustained release. - International Journal of Pharmaceutics, 326, 100-106, 2006.
30. Sinclair G.W., Peppas N.A. - Analisys of non-fickian transport polymers using semplified exponential expression. - J. Membr. Sci., 17, 329-331, 1984.
31. Tan X., Meltzer N., Lindenbaum S. - Determination of the kinetics of degradation of 13-cis-retinoic acid and all-trans retinoic acid in solution. - J. Pharm. Biomed. Anal., 11, 817-822, 1993.
32. Brisaert M., Plaizier-Vercammen J. - Investigation on the photostability of a tretinoin lotion and stabilization with additives. - Int. J Pharm., 199, 49-57, 2000.
33. Yanzhi W., Yihui D., Shirui M., Shengxuan J., Jian W., Dianzhou B. - Characterization and body distribution of β-elemene solid lipid nanoparticles (SLN). - Drug Development and Industrial Pharmacy, 31, 769-778, 2005.
34. Domb A.J. - Lipospheres for controlled delivery of substances. - United States Patent, 1993, USS 188837.
35. Mehnert W., Mader K. - Solid lipid nanoparticles: production, characterization and applications. - Advanced Drug Delivery Reviews, 47, 165-196, 2001.
36. Siekmann B., Westesen K. - Submicron-sized parenteral carrier systems based on solid lipids. - Pharm. Pharmacol. Lett., 1, 123-126, 1992.
37. Olbrich C., Muller R.H. - Enzymatic degradation of SLN effect of surfactant and surfactant mixtures. - Int. J. Pharm., 180, 31-39, 1999.
38. Müller R.H., Heinemann S. - Fat emulsions for parenteral nutrition. I. Evaluation of microscopic and laser light scattering methods for the determination of the physical stability. - Clin. Nutr., 11, 223-272, 1992.
39. Ahlin P., Kristl J., Smid-Kobar J. - Optimization of procedure parameters and physical stability of solid lipid nanoparticles in dispersions. - Acta Pharm., 48, 257-267, 1998.
40. Asasutjarit R., Lorenzen S.I., Sirivichayakul S. Ruxrungtham K., Ruktanonchai U., Ritthidej G.C. - Effect of solid lipid nanoparticles formulation compositions on their size, zeta potential and potential for in vitro phis-hiv-hugag transfection. - Pharm. Res., 24, 1098-1107, 2007.
41. Müller R. H., Radtke M., Wissing S. A. - Nanostructured lipid matrices for improved microencapsulation of drugs. - Int. J. Pharm., 242, 121-128, 2002.
42. Mühlen A., Schwarz C., Mehnert W. - Solid lipid nanoparticles (SLN) for controlled drug delivery, Drug release and release mechanism. - European Journal of Pharmaceutics and Biopharmaceutics, 45, 149-155, 1998.