Synthesis and cerebral uptake of 1-(1-[11C]methyl-1H-pyrrol-2- yl)-2-phenyl-2-(1-pyrrolidinyl)ethanone, a novel tracer for positron emission tomography studies of monoamine oxidase type A

Journal of Medicinal Chemistry

Volumn 51, Issue 6, 2008, Pages 1617-1622

  Jensen, Svend Borup ^a   Di Santo, Roberto ^b   Olsen, Aage Kristian ^a   Pedersen, Kasper ^a   Costi, Roberta ^b   Cirilli, Roberto ^c   Cumming, Paul ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

1 (1 METHYL IH PYRROL 2YL) 2 PHENYL 2 (1 PYRROLIDINYL)ETHANONE C 11; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; HARMINE; HARMINE C 11; PARGYLINE; TRACER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG METABOLISM; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG UPTAKE; FEMALE; FOREBRAIN; MESENCEPHALON; NONHUMAN; POSITRON EMISSION TOMOGRAPHY;

ANIMALS; BINDING SITES; BRAIN; CEREBRAL CORTEX; FEMALE; MOLECULAR STRUCTURE; MONOAMINE OXIDASE; POSITRON-EMISSION TOMOGRAPHY; PYRROLES; PYRROLIDINES; STEREOISOMERISM; SWINE; TISSUE DISTRIBUTION;

EID: 41249095463     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm701378e     Document Type: Article

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