메뉴 건너뛰기




Volumn 37, Issue 10, 1998, Pages 804-817

Modification of Human T-Cell Responses by Altered Peptide Ligands: A New Approach to Antigen-specific Modification

Author keywords

Altered peptide ligands; Antigen presentation; Antigenic peptides; Cd4+ t cells; Human leukocyte antigen (hla)class ii molecule; T cell activation

Indexed keywords

ANTIGEN; AUTOANTIGEN; BACTERIAL ANTIGEN; BCL2L1 PROTEIN, HUMAN; BCL2L1 PROTEIN, MOUSE; CHOLINERGIC RECEPTOR; HLA D ANTIGEN; HRAS PROTEIN, HUMAN; LIGAND; LYMPHOCYTE ANTIGEN RECEPTOR; LYMPHOKINE; PEPTIDE FRAGMENT; PROTEIN BCL 2; PROTEIN BCL X; PROTEIN P21;

EID: 0032176307     PISSN: 09182918     EISSN: None     Source Type: Journal    
DOI: 10.2169/internalmedicine.37.804     Document Type: Article
Times cited : (17)

References (96)
  • 1
    • 0027468145 scopus 로고
    • The biochemistry and cell biology of antigen processing and presentation
    • WE Paul, Fathman CG, Metzger H, Ed. Annual Reviews Inc. Palo Alto, CA
    • Germain RN, Margulies DH. The biochemistry and cell biology of antigen processing and presentation, in: Annual Review of Immunology, WE Paul, Fathman CG, Metzger H, Ed. Vol. 11, Annual Reviews Inc. Palo Alto, CA, 1993, p. 403-450.
    • (1993) Annual Review of Immunology , vol.11 , pp. 403-450
    • Germain, R.N.1    Margulies, D.H.2
  • 2
    • 0027296020 scopus 로고
    • HLA DR4w4-binding motifs illustrate the biochemical basis of degeneracy and specificity in peptide-DR interactions
    • Sette A, Sidney J, Oseroff C, et al. HLA DR4w4-binding motifs illustrate the biochemical basis of degeneracy and specificity in peptide-DR interactions. J Immunol 151: 3163-3170, 1993.
    • (1993) J Immunol , vol.151 , pp. 3163-3170
    • Sette, A.1    Sidney, J.2    Oseroff, C.3
  • 3
    • 0027185153 scopus 로고
    • Promiscuous and allele-specific anchors in HLA-DR-binding peptides
    • Hammer J, Valsasnini P, Tolba K, et al. Promiscuous and allele-specific anchors in HLA-DR-binding peptides. Cell 74: 197-203, 1993.
    • (1993) Cell , vol.74 , pp. 197-203
    • Hammer, J.1    Valsasnini, P.2    Tolba, K.3
  • 5
    • 0028023507 scopus 로고
    • Allele specificity of structural requirement for peptides bound to HLA- DRB 1*0405 and -DRB 1*0406 complexes: Implication for the HLA- associated susceptibility to methimazole-induced insulin autoimmune syndrome
    • Matsushita S,Takahashi K, Motoki M, Komoriya K, Ikagawa S, Nishimura Y. Allele specificity of structural requirement for peptides bound to HLA- DRB 1*0405 and -DRB 1*0406 complexes: Implication for the HLA- associated susceptibility to methimazole-induced insulin autoimmune syndrome. J Exp Med 180: 873-883, 1994.
    • (1994) J Exp Med , vol.180 , pp. 873-883
    • Matsushita, S.1    Takahashi, K.2    Motoki, M.3    Komoriya, K.4    Ikagawa, S.5    Nishimura, Y.6
  • 6
    • 0028952168 scopus 로고
    • Peptide binding specificity of HLA- DR4 molecules: Correlation with rheumatoid arthritis association
    • Hammer J, Gallazzi F, Bono E, et al. Peptide binding specificity of HLA- DR4 molecules: Correlation with rheumatoid arthritis association. J Exp Med 181: 1847-1855, 1995.
    • (1995) J Exp Med , vol.181 , pp. 1847-1855
    • Hammer, J.1    Gallazzi, F.2    Bono, E.3
  • 7
    • 0027217789 scopus 로고
    • Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1
    • Brown JH, Jardetzky TS, Gorga JC, et al. Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature 364: 33-39, 1993.
    • (1993) Nature , vol.364 , pp. 33-39
    • Brown, J.H.1    Jardetzky, T.S.2    Gorga, J.C.3
  • 8
    • 0028823585 scopus 로고
    • The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3
    • Ghosh P, Amaya M, Mellins E, Wiley DC. The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3. Nature 378: 457-462, 1995.
    • (1995) Nature , vol.378 , pp. 457-462
    • Ghosh, P.1    Amaya, M.2    Mellins, E.3    Wiley, D.C.4
  • 9
    • 0030701632 scopus 로고    scopus 로고
    • X-ray crystal structure of HLA-DR4 (DRA*0401, DRB1*0401) complexed with a peptide from human collagen II
    • Dessen A, Lawrence CM, Cupo S, Zaller DM, Wiley DC. X-ray crystal structure of HLA-DR4 (DRA*0401, DRB1*0401) complexed with a peptide from human collagen II. Immunity 7: 473-481, 1997.
    • (1997) Immunity , vol.7 , pp. 473-481
    • Dessen, A.1    Lawrence, C.M.2    Cupo, S.3    Zaller, D.M.4    Wiley, D.C.5
  • 10
    • 0028348369 scopus 로고
    • Crystal structure of the human class II MHC protein HLA-DR 1 complexed with an influenza virus peptide
    • Stern LJ, Brown JH, Jardetzky TS, et al. Crystal structure of the human class II MHC protein HLA-DR 1 complexed with an influenza virus peptide Nature 368: 215-221, 1994.
    • (1994) Nature , vol.368 , pp. 215-221
    • Stern, L.J.1    Brown, J.H.2    Jardetzky, T.S.3
  • 11
    • 0025793243 scopus 로고
    • Single amino acid changes in DR and antigen define residues critical for peptide-MHC binding and T cell recognition
    • Krieger JI, Karr RW, Grey HM, et al. Single amino acid changes in DR and antigen define residues critical for peptide-MHC binding and T cell recognition. J Immunol 146: 2331-2340, 1991.
    • (1991) J Immunol , vol.146 , pp. 2331-2340
    • Krieger, J.I.1    Karr, R.W.2    Grey, H.M.3
  • 12
    • 0026434554 scopus 로고
    • Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand
    • Evavold BD, Allen PM. Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand. Science 252: 1308-1310, 1991.
    • (1991) Science , vol.252 , pp. 1308-1310
    • Evavold, B.D.1    Allen, P.M.2
  • 13
    • 0026042326 scopus 로고
    • Regulation of the immune response to peptide antigens: Differential induction of immediate-type hypersensitivity and T cell proliferation due to changes in either peptide structure or major histocompatibility complex haplo-type
    • Soloway P, Fish S, Passmore H, Gefter M, Coffee R, Manser T. Regulation of the immune response to peptide antigens: differential induction of immediate-type hypersensitivity and T cell proliferation due to changes in either peptide structure or major histocompatibility complex haplo-type. J Exp Med 174: 847-858, 1991.
    • (1991) J Exp Med , vol.174 , pp. 847-858
    • Soloway, P.1    Fish, S.2    Passmore, H.3    Gefter, M.4    Coffee, R.5    Manser, T.6
  • 14
    • 0026503161 scopus 로고
    • Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor
    • De Magistris MT, Alexander J, Coggeshall M, et al. Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor. Cell 68: 625-634, 1992.
    • (1992) Cell , vol.68 , pp. 625-634
    • De Magistris, M.T.1    Alexander, J.2    Coggeshall, M.3
  • 15
    • 0027298445 scopus 로고
    • Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells
    • Sloan-Lancaster J, Evavold BD, Allen PM. Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells. Nature 363: 156-159, 1993.
    • (1993) Nature , vol.363 , pp. 156-159
    • Sloan-Lancaster, J.1    Evavold, B.D.2    Allen, P.M.3
  • 16
    • 0027238112 scopus 로고
    • T cell receptor antagonism mediated by interaction between T cell receptor junctional residues and peptide antigen analogues
    • Ostrov D, Krieger J, Sidney J, Sette A, Concannon P. T cell receptor antagonism mediated by interaction between T cell receptor junctional residues and peptide antigen analogues. J Immunol 150: 4277-4283, 1993.
    • (1993) J Immunol , vol.150 , pp. 4277-4283
    • Ostrov, D.1    Krieger, J.2    Sidney, J.3    Sette, A.4    Concannon, P.5
  • 17
    • 0027450760 scopus 로고
    • Functional consequences of engagement of the T cell receptor by low affinity ligands
    • Alexander J, Snoke K, Ruppert J, et al. Functional consequences of engagement of the T cell receptor by low affinity ligands. J Immunol 150: 1-7, 1993.
    • (1993) J Immunol , vol.150 , pp. 1-7
    • Alexander, J.1    Snoke, K.2    Ruppert, J.3
  • 18
    • 0028025705 scopus 로고
    • Th2 cell clonal anergy as a consequence of partial activation
    • Sloan-Lancaster J, Evavold BD, Allen PM. Th2 cell clonal anergy as a consequence of partial activation. J Exp Med 180: 1195-1205, 1994.
    • (1994) J Exp Med , vol.180 , pp. 1195-1205
    • Sloan-Lancaster, J.1    Evavold, B.D.2    Allen, P.M.3
  • 19
    • 0028956146 scopus 로고
    • Modulation of cytokine patterns of human autoreactive T cell clones by a single amino acid substitution of their peptide ligand
    • Windhagen A, Scholz C, Hollsberg P, Fukaura H, Sette A, Hafler DA. Modulation of cytokine patterns of human autoreactive T cell clones by a single amino acid substitution of their peptide ligand. Immunity 2: 373-380, 1995.
    • (1995) Immunity , vol.2 , pp. 373-380
    • Windhagen, A.1    Scholz, C.2    Hollsberg, P.3    Fukaura, H.4    Sette, A.5    Hafler, D.A.6
  • 20
    • 0030293628 scopus 로고    scopus 로고
    • Response of an human T cell clone to a large panel of altered peptide ligands carrying single residue substitutions in an antigenic peptide: Characterization and frequencies of TCR agonism and TCR antagonism with or without partial activation
    • Chen YZ, Matsushita S, Nishimura Y. Response of an human T cell clone to a large panel of altered peptide ligands carrying single residue substitutions in an antigenic peptide: characterization and frequencies of TCR agonism and TCR antagonism with or without partial activation. J Immunol 157: 3783-3790, 1996.
    • (1996) J Immunol , vol.157 , pp. 3783-3790
    • Chen, Y.Z.1    Matsushita, S.2    Nishimura, Y.3
  • 21
    • 0030023918 scopus 로고    scopus 로고
    • Single amino acid substitutions on a Japanese cedar pollen allergen (Cry j 1)- Derived peptide induced alterations in human T cell responses and T cell receptor antagonism
    • Ikagawa S, Matsushita S, Chen YZ, Ishikawa T, Nishimura Y. Single amino acid substitutions on a Japanese cedar pollen allergen (Cry j 1)- derived peptide induced alterations in human T cell responses and T cell receptor antagonism. J Allergy Clin Immunol 97: 53-64, 1996.
    • (1996) J Allergy Clin Immunol , vol.97 , pp. 53-64
    • Ikagawa, S.1    Matsushita, S.2    Chen, Y.Z.3    Ishikawa, T.4    Nishimura, Y.5
  • 22
    • 0030443348 scopus 로고    scopus 로고
    • Altered TCR ligands affect APC responses: Upregulation of IL-12 by an analogue peptide
    • Matsuoka T, Kohrogi H, Ando M, Nishimura Y, Matsushita S. Altered TCR ligands affect APC responses: Upregulation of IL-12 by an analogue peptide. J Immunol 157: 4837-4843, 1996.
    • (1996) J Immunol , vol.157 , pp. 4837-4843
    • Matsuoka, T.1    Kohrogi, H.2    Ando, M.3    Nishimura, Y.4    Matsushita, S.5
  • 23
    • 0031570440 scopus 로고    scopus 로고
    • Evidence for self- and non-self- peptide partial agonists that prolong clonal survival of mature T cells in vitro
    • Matsushila S, Kohsaka H, Nishimura Y. Evidence for self- and non-self- peptide partial agonists that prolong clonal survival of mature T cells in vitro. J Immunol 158: 5685-5691, 1997.
    • (1997) J Immunol , vol.158 , pp. 5685-5691
    • Matsushila, S.1    Kohsaka, H.2    Nishimura, Y.3
  • 24
    • 0027409792 scopus 로고
    • Peptide-major histocompatibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related differences in T cell receptor-dependent intracellular signaling
    • Racioppi L, Ronchese F, Matis LA, Germain RN. Peptide-major histocompatibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related differences in T cell receptor-dependent intracellular signaling. J Exp Med 177: 1047-1060, 1993.
    • (1993) J Exp Med , vol.177 , pp. 1047-1060
    • Racioppi, L.1    Ronchese, F.2    Matis, L.A.3    Germain, R.N.4
  • 26
    • 0027967385 scopus 로고
    • Partial T cell signaling: Altered phospho-ζ and lack of zap70 recruitment in APL- Induced T cell anergy
    • Sloan-Lancaster J, Shaw AS, Rothhard JB, Allen PM. Partial T cell signaling: altered phospho-ζ and lack of zap70 recruitment in APL- induced T cell anergy. Cell 79: 913-922, 1994.
    • (1994) Cell , vol.79 , pp. 913-922
    • Sloan-Lancaster, J.1    Shaw, A.S.2    Rothhard, J.B.3    Allen, P.M.4
  • 27
    • 0028902752 scopus 로고
    • ζ Phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists
    • Madrenas J, Wange RL, Wang JL, Isakov N, Samelson LE, Germain RN. ζ Phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists. Science 267: 515-518, 1995.
    • (1995) Science , vol.267 , pp. 515-518
    • Madrenas, J.1    Wange, R.L.2    Wang, J.L.3    Isakov, N.4    Samelson, L.E.5    Germain, R.N.6
  • 28
    • 0029952074 scopus 로고    scopus 로고
    • Selective activation of the calcium signaling pathway by altered peptide ligands
    • Sloan-Lancaster J, Steinberg TH, Allen PM. Selective activation of the calcium signaling pathway by altered peptide ligands. J Exp Med 184: 1525-1530, 1996.
    • (1996) J Exp Med , vol.184 , pp. 1525-1530
    • Sloan-Lancaster, J.1    Steinberg, T.H.2    Allen, P.M.3
  • 29
    • 0030218942 scopus 로고    scopus 로고
    • Altered T cell receptor ligands trigger a subset of early T cell signals
    • Rabinowitz JD, Beeson C, Wulfing C,et al. Altered T cell receptor ligands trigger a subset of early T cell signals. Immunity 5: 125-135, 1996.
    • (1996) Immunity , vol.5 , pp. 125-135
    • Rabinowitz, J.D.1    Beeson, C.2    Wulfing, C.3
  • 31
    • 0003104975 scopus 로고    scopus 로고
    • A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists
    • Lyons DS, Lieberman SA, Hampl J, et al. A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists. Immunity 5: 53-61, 1996.
    • (1996) Immunity , vol.5 , pp. 53-61
    • Lyons, D.S.1    Lieberman, S.A.2    Hampl, J.3
  • 32
    • 0026437671 scopus 로고
    • HLA- DR4 genotype and insulin-processing in insulin autoimmune syndrome
    • Uchigata Y, Omori Y, Nieda M, Kuwata S, Tokunaga K, Juji T. HLA- DR4 genotype and insulin-processing in insulin autoimmune syndrome. Lancet 340: 1467, 1992.
    • (1992) Lancet , vol.340 , pp. 1467
    • Uchigata, Y.1    Omori, Y.2    Nieda, M.3    Kuwata, S.4    Tokunaga, K.5    Juji, T.6
  • 33
    • 0021690204 scopus 로고
    • Myasthenia gravis and myasthenic syndromes
    • Engel AG. Myasthenia gravis and myasthenic syndromes. Ann Neurol 16: 519-534, 1984.
    • (1984) Ann Neurol , vol.16 , pp. 519-534
    • Engel, A.G.1
  • 34
    • 0023225233 scopus 로고
    • Immunopathogenesis and treatment of myasthenia gravis
    • Levinson AI, Zweiman B, Lisak RP. Immunopathogenesis and treatment of myasthenia gravis. J Clin Immunol 7: 187-197, 1987.
    • (1987) J Clin Immunol , vol.7 , pp. 187-197
    • Levinson, A.I.1    Zweiman, B.2    Lisak, R.P.3
  • 35
    • 0024358811 scopus 로고
    • Immunogeneticsol experimental autoimmune myasthenia gravis
    • Christadoss P. Immunogeneticsol experimental autoimmune myasthenia gravis. Crit Rev Immunol 9: 247-278, 1989.
    • (1989) Crit Rev Immunol , vol.9 , pp. 247-278
    • Christadoss, P.1
  • 37
    • 0012107789 scopus 로고
    • Myasthenia Gravis
    • Lewis PR, Ed. Ninth Edition, Williams & Wilkins, PA
    • Audrey SP, Lewis PR. Myasthenia Gravis. In: Merrtt's Textbook of Neurology, Lewis PR, Ed. Ninth Edition, Williams & Wilkins, PA, 1995, p. 754-761.
    • (1995) Merrtt's Textbook of Neurology , pp. 754-761
    • Audrey, S.P.1    Lewis, P.R.2
  • 38
    • 0016913295 scopus 로고
    • On the significance of HL-A and LD antigens in myasthenia gravis
    • Pirskanen R. On the significance of HL-A and LD antigens in myasthenia gravis. Ann N Y Acad Sci 274: 451-460, 1976.
    • (1976) Ann N Y Acad Sci , vol.274 , pp. 451-460
    • Pirskanen, R.1
  • 40
    • 0025091114 scopus 로고
    • HLA antigens in Japanese patients with myasthenia gravis
    • Matsuki K, Juji T, Tokunaga K, et al. HLA antigens in Japanese patients with myasthenia gravis. J Clin Invest 86: 392-399, 1990.
    • (1990) J Clin Invest , vol.86 , pp. 392-399
    • Matsuki, K.1    Juji, T.2    Tokunaga, K.3
  • 41
    • 0027254596 scopus 로고
    • HLA haplotype in myasthenia gravis (MG) of Japanese children. Correlative studies between MG patients and their normal siblings and parents
    • Nomura Y, Ehara M, Matsuki K, Juji T, Segawa M. HLA haplotype in myasthenia gravis (MG) of Japanese children. Correlative studies between MG patients and their normal siblings and parents. Ann N Y Acad Sci 681: 581-583, 1993.
    • (1993) Ann N Y Acad Sci , vol.681 , pp. 581-583
    • Nomura, Y.1    Ehara, M.2    Matsuki, K.3    Juji, T.4    Segawa, M.5
  • 43
    • 0025313553 scopus 로고
    • The human muscle nicotinic acetylcholine receptor alpha-subunit exist as two isoforms: A novel exon
    • Beeson D, Morris A, Vincent A, Newsom-Davis J. The human muscle nicotinic acetylcholine receptor alpha-subunit exist as two isoforms: a novel exon. EMBO J 9: 2101-2106, 1990.
    • (1990) EMBO J , vol.9 , pp. 2101-2106
    • Beeson, D.1    Morris, A.2    Vincent, A.3    Newsom-Davis, J.4
  • 44
    • 0026342991 scopus 로고
    • Two isoforms of the muscle acetylcholine receptor alpha-subunit are translated in the human cell line TE671
    • Morris A, Beeson D, Jacobson L, Baggi F, Vincent A, Newsom-Davis J. Two isoforms of the muscle acetylcholine receptor alpha-subunit are translated in the human cell line TE671. FEBS Lett 295: 116-118, 1991.
    • (1991) FEBS Lett , vol.295 , pp. 116-118
    • Morris, A.1    Beeson, D.2    Jacobson, L.3    Baggi, F.4    Vincent, A.5    Newsom-Davis, J.6
  • 45
    • 0001707341 scopus 로고
    • Localization of the main immunogenic region of human muscle acetylcholine receptor to residue 67-76 of the alpha subunit
    • Tzartos SJ, Kokla A, Walgrave SL, Conti-Tronconi BM. Localization of the main immunogenic region of human muscle acetylcholine receptor to residue 67-76 of the alpha subunit. Proc Natl Acad Sci USA 85: 2899-2903, 1988.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 2899-2903
    • Tzartos, S.J.1    Kokla, A.2    Walgrave, S.L.3    Conti-Tronconi, B.M.4
  • 47
    • 0027194314 scopus 로고
    • Approaches for studying the pathogenic T cells in autoimmune patients
    • Willcox N, Baggi F, Batocchi AP, et al. Approaches for studying the pathogenic T cells in autoimmune patients. Am N Y Acad Sci 681: 219-237, 1993.
    • (1993) Am N Y Acad Sci , vol.681 , pp. 219-237
    • Willcox, N.1    Baggi, F.2    Batocchi, A.P.3
  • 48
    • 0027176664 scopus 로고
    • Thelpercell recognition of muscle acetylcholine receptor in myasthenia gravis. Epitopes on the gamma and delta subunits
    • Manfredi AA, Protti MP, Dalton MW, Howard JF Jr, Conti-Tronconi BM. Thelpercell recognition of muscle acetylcholine receptor in myasthenia gravis. Epitopes on the gamma and delta subunits. J Clin Invest 92: 1055-1067, 1993.
    • (1993) J Clin Invest , vol.92 , pp. 1055-1067
    • Manfredi, A.A.1    Protti, M.P.2    Dalton, M.W.3    Howard Jr., J.F.4    Conti-Tronconi, B.M.5
  • 50
    • 0029143341 scopus 로고
    • Peptide-selected T cell lines from myasthenia gravis patients and controls recognize epitopes that are not processed from whole acetylcholine receptor
    • Matsuo H, Batocchi AP, Hawke S, et al. Peptide-selected T cell lines from myasthenia gravis patients and controls recognize epitopes that are not processed from whole acetylcholine receptor. J Immunol 155: 3683-3692, 1995.
    • (1995) J Immunol , vol.155 , pp. 3683-3692
    • Matsuo, H.1    Batocchi, A.P.2    Hawke, S.3
  • 51
    • 0031459009 scopus 로고    scopus 로고
    • Immuno-suppressive peptides for a human T cell clone autoreactive to a unique acetylcholine receptor α subunit peptide presented by the disease susceptible HLA-DQ6 in infant- Onset myasthenia gravis
    • Kanai T, Nomura Y, Segawa M, et al. Immuno-suppressive peptides for a human T cell clone autoreactive to a unique acetylcholine receptor α subunit peptide presented by the disease susceptible HLA-DQ6 in infant- onset myasthenia gravis. Human Immunol 56: 28-38, 1997.
    • (1997) Human Immunol , vol.56 , pp. 28-38
    • Kanai, T.1    Nomura, Y.2    Segawa, M.3
  • 53
    • 0028920179 scopus 로고
    • + cytotoxic T lymphocytes stimulated by immobilized anti-CD3 monoclonal antibody and interleukin-2 in cancer patients
    • + cytotoxic T lymphocytes stimulated by immobilized anti-CD3 monoclonal antibody and interleukin-2 in cancer patients. Int J Cancer 60: 802-807, 1995.
    • (1995) Int J Cancer , vol.60 , pp. 802-807
    • Tani, M.1    Tanimura, H.2    Yamaue, H.3
  • 54
    • 0024376173 scopus 로고
    • Ras oncogenes in human cancer: A review
    • published erratum appears in Cancer Res Feb 50: 1352, 1990
    • Bos JL. ras oncogenes in human cancer: a review Cancer Res 49: 4682-4689, 1989 (published erratum appears in Cancer Res Feb 50: 1352, 1990).
    • (1989) Cancer Res , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 55
    • 0026074766 scopus 로고
    • Human T lymphocytes recognize a peptide of single point-mutated, oncogenic ras proteins
    • Jung S, Schluesener HJ. Human T lymphocytes recognize a peptide of single point-mutated, oncogenic ras proteins. J Exp Med 173: 273-276, 1991.
    • (1991) J Exp Med , vol.173 , pp. 273-276
    • Jung, S.1    Schluesener, H.J.2
  • 56
    • 0027428762 scopus 로고
    • Overlapping epitopes encompassing a point mutation (12 Gly → Arg) in p21 ras can be recognized by HLA-DR, -DP and -DQ restricted T cells
    • Fossum B, Gedde-Dahl T, Hansen T, Eriksen JA, Thorsby E, Gaudernack G. Overlapping epitopes encompassing a point mutation (12 Gly → Arg) in p21 ras can be recognized by HLA-DR, -DP and -DQ restricted T cells. Eur J Immunol 23: 2687-2691, 1993.
    • (1993) Eur J Immunol , vol.23 , pp. 2687-2691
    • Fossum, B.1    Gedde-Dahl, T.2    Hansen, T.3    Eriksen, J.A.4    Thorsby, E.5    Gaudernack, G.6
  • 57
    • 0027477906 scopus 로고
    • T cell clones specific for p21 ras-derived peptides: Characterization of their fine specificity and HLA restriction
    • Gedde-Dahl T, fossum B, Eriksen JA, Thorsby E, Gaudernack G. T cell clones specific for p21 ras-derived peptides: characterization of their fine specificity and HLA restriction. Eur J Immunol 23: 754-760, 1993.
    • (1993) Eur J Immunol , vol.23 , pp. 754-760
    • Gedde-Dahl, T.1    Fossum, B.2    Eriksen, J.A.3    Thorsby, E.4    Gaudernack, G.5
  • 58
    • 0028924505 scopus 로고
    • Induction and characterization of cytotoxic T-lymphocytes recognizinga mutated p21 ras peptide presented by HLA-A*0201
    • Van Elsas A, Nijman HW, Van der Minne CE, et al. Induction and characterization of cytotoxic T-lymphocytes recognizinga mutated p21 ras peptide presented by HLA-A*0201. Int J Cancer 61: 389-396, 1995.
    • (1995) Int J Cancer , vol.61 , pp. 389-396
    • Van Elsas, A.1    Nijman, H.W.2    Van der Minne, C.E.3
  • 59
    • 0026564444 scopus 로고
    • Memory T cells of a patient with follicular thyroid carcinoma recognize peptides derived from mutated p21 ras (Gln → Leu61)
    • Gedde-Dahl Td, Spurkland A, Eriksen JA, Thorsby E, Gaudernack G. Memory T cells of a patient with follicular thyroid carcinoma recognize peptides derived from mutated p21 ras (Gln → Leu61). Int Immunol 4: 1331-1337, 1992.
    • (1992) Int Immunol , vol.4 , pp. 1331-1337
    • Gedde-Dahl, Td.1    Spurkland, A.2    Eriksen, J.A.3    Thorsby, E.4    Gaudernack, G.5
  • 60
    • 0028169898 scopus 로고
    • 13Gly → Asp mutation is recognized by HLA-DQ7 restricted T cells in a patient with colorectal cancer. Modifying effect of DQ7 on established cancers harbouring this mutation?
    • 13Gly → Asp mutation is recognized by HLA-DQ7 restricted T cells in a patient with colorectal cancer. Modifying effect of DQ7 on established cancers harbouring this mutation? Int J Cancer 58: 506-511, 1994.
    • (1994) Int J Cancer , vol.58 , pp. 506-511
    • Fossum, B.1    Breivik, J.2    Meling, G.I.3
  • 62
    • 0028856743 scopus 로고
    • Vaccination with mutant ras peptides and induction of T-cell responsiveness in pancreatic carcinoma patients carrying the corresponding RAS mutation
    • Gjertsen MK, Bakka A, Breivik J, et al. Vaccination with mutant ras peptides and induction of T-cell responsiveness in pancreatic carcinoma patients carrying the corresponding RAS mutation. Lancet 346: 1399-1400, 1995.
    • (1995) Lancet , vol.346 , pp. 1399-1400
    • Gjertsen, M.K.1    Bakka, A.2    Breivik, J.3
  • 63
    • 0029043003 scopus 로고
    • + T-cell immunity to mutated ras protein in pancreatic and colon cancer patients
    • + T-cell immunity to mutated ras protein in pancreatic and colon cancer patients. Cancer Res 55: 2984-2987, 1995.
    • (1995) Cancer Res , vol.55 , pp. 2984-2987
    • Qin, H.1    Chen, W.2    Takahashi, M.3
  • 64
    • 0028863172 scopus 로고
    • Induction of T-cell immunity against Ras oncoproteins by soluble protein or Ras-expressing Escherichia coli
    • Fenton RG, Keller CJ, Hanna N, Taub DD. Induction of T-cell immunity against Ras oncoproteins by soluble protein or Ras-expressing Escherichia coli. J Natl Cancer Inst 87: 1853-1861, 1995.
    • (1995) J Natl Cancer Inst , vol.87 , pp. 1853-1861
    • Fenton, R.G.1    Keller, C.J.2    Hanna, N.3    Taub, D.D.4
  • 66
    • 0031035481 scopus 로고    scopus 로고
    • Augmentation of immune response by an analog of the antigenic peptide in a human T-cell clone recognizing mutated Ras-derived peptides
    • Yokomizo H, Matsushita S, Fujisao S, et al. Augmentation of immune response by an analog of the antigenic peptide in a human T-cell clone recognizing mutated Ras-derived peptides. Human Immunol 52: 22-32, 1997.
    • (1997) Human Immunol , vol.52 , pp. 22-32
    • Yokomizo, H.1    Matsushita, S.2    Fujisao, S.3
  • 67
    • 0026015286 scopus 로고
    • On the interaction of promiscuous antigenic peptides with different DR alleles. Identification of common structural motifs
    • O'Sullivan D, Arrhenius T, Sidney J, et al. On the interaction of promiscuous antigenic peptides with different DR alleles. Identification of common structural motifs. J Immunol 147: 2663-2669, 1991.
    • (1991) J Immunol , vol.147 , pp. 2663-2669
    • O'Sullivan, D.1    Arrhenius, T.2    Sidney, J.3
  • 68
    • 0026706746 scopus 로고
    • Identification of a motif for HLA-DR1 binding peptides using M13 display libraries
    • Hammer J, Takacs B, Sinigaglia F. Identification of a motif for HLA-DR1 binding peptides using M13 display libraries. J Exp Med 176: 1007-1013, 1992.
    • (1992) J Exp Med , vol.176 , pp. 1007-1013
    • Hammer, J.1    Takacs, B.2    Sinigaglia, F.3
  • 69
    • 85034476583 scopus 로고    scopus 로고
    • + T cell lines reactive with a self-K-ras-derived peptide in vitro, using a mAb to CD29
    • + T cell lines reactive with a self-K-ras-derived peptide in vitro, using a mAb to CD29. Human Immunol 52: 179-182, 1998.
    • (1998) Human Immunol , vol.52 , pp. 179-182
    • Tanaka, Y.1    Ogawa, M.2    Nishimura, Y.3    Matsushita, S.4
  • 70
    • 0029928417 scopus 로고    scopus 로고
    • The expanding universe of T-cell subsets: Th1, Th2 and more
    • Mosmann TR, Sad S. The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol Today 17: 138-146, 1996.
    • (1996) Immunol Today , vol.17 , pp. 138-146
    • Mosmann, T.R.1    Sad, S.2
  • 71
    • 0026328818 scopus 로고
    • Generation and analysis of interleukin-4 deficient mice
    • Kuhn R, Rajewsky K, Muller W. Generation and analysis of interleukin-4 deficient mice. Science 254: 707-710, 1991.
    • (1991) Science , vol.254 , pp. 707-710
    • Kuhn, R.1    Rajewsky, K.2    Muller, W.3
  • 74
    • 0027153986 scopus 로고
    • Identification of multiple T cell epitopes on Bet v I, the major birch pollen allergen, using specific T cell clones and overlapping peptides
    • Ebner C, Szépfalusi Z, Ferreira F, et al. Identification of multiple T cell epitopes on Bet v I, the major birch pollen allergen, using specific T cell clones and overlapping peptides. J Immunol 150: 1047-1054, 1993.
    • (1993) J Immunol , vol.150 , pp. 1047-1054
    • Ebner, C.1    Szépfalusi, Z.2    Ferreira, F.3
  • 75
    • 0027177930 scopus 로고
    • T cell epitopes of house dust mite major allergen Der p II
    • Joost van Neerven R, van H, Ringrose JH, et al. T cell epitopes of house dust mite major allergen Der p II. J Immunol 151: 2326-2335, 1993.
    • (1993) J Immunol , vol.151 , pp. 2326-2335
    • Joost van Neerven, R.1    Van, H.2    Ringrose, J.H.3
  • 77
    • 0028330701 scopus 로고
    • Recognition of T cell epitopes and lymphokine secretion by rye grass allergen Lolium perenne I-specitic human T cell clones
    • Spiegelberg HL, Beck L, Stevenson DD, Ishioka GY. Recognition of T cell epitopes and lymphokine secretion by rye grass allergen Lolium perenne I-specitic human T cell clones. J Immunol 152: 4706-4711, 1994.
    • (1994) J Immunol , vol.152 , pp. 4706-4711
    • Spiegelberg, H.L.1    Beck, L.2    Stevenson, D.D.3    Ishioka, G.Y.4
  • 78
    • 0031003113 scopus 로고    scopus 로고
    • Dermatophagoides farinae-1-derived peptides and HLA molecules recognized by T cells from atopic individuals
    • Matsuoka T, Kohrogi H, Ando M, Nishimura Y, Matsushita S. Dermatophagoides farinae-1-derived peptides and HLA molecules recognized by T cells from atopic individuals. Int Arch Allergy Immunol 112: 365-370, 1997.
    • (1997) Int Arch Allergy Immunol , vol.112 , pp. 365-370
    • Matsuoka, T.1    Kohrogi, H.2    Ando, M.3    Nishimura, Y.4    Matsushita, S.5
  • 81
    • 0028979705 scopus 로고
    • Specific T cell recognition of minimally homologous peptides: Evidence for multiple endogenous ligands
    • Evavold BD, Sloan-Lancaster J, Wilson KJ, Rothbard JB, Allen PM. Specific T cell recognition of minimally homologous peptides: evidence for multiple endogenous ligands. Immunity 2: 655-663, 1995.
    • (1995) Immunity , vol.2 , pp. 655-663
    • Evavold, B.D.1    Sloan-Lancaster, J.2    Wilson, K.J.3    Rothbard, J.B.4    Allen, P.M.5
  • 83
    • 0028926223 scopus 로고
    • Molecular mimicry in T cell- Mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein
    • Wucherpfennig KW, Strominger JL. Molecular mimicry in T cell- mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein. Cell 80: 695-705, 1995.
    • (1995) Cell , vol.80 , pp. 695-705
    • Wucherpfennig, K.W.1    Strominger, J.L.2
  • 84
    • 0028905099 scopus 로고
    • HLA- DRB4*0101 -restricted immunodominant T cell autoepitope of pyruvate dehydrogenase complex in primary biliary cirrhosis: Evidence of molecular mimicry in human autoimmune diseases
    • Shimoda S, Nakamura M, Ishibashi H, Hayashida K, Niho Y. HLA- DRB4*0101 -restricted immunodominant T cell autoepitope of pyruvate dehydrogenase complex in primary biliary cirrhosis: evidence of molecular mimicry in human autoimmune diseases. J Exp Med 181: 1835-1845, 1995.
    • (1995) J Exp Med , vol.181 , pp. 1835-1845
    • Shimoda, S.1    Nakamura, M.2    Ishibashi, H.3    Hayashida, K.4    Niho, Y.5
  • 85
    • 0026534109 scopus 로고
    • Immunoreactivity of a 10-kDa antigen of Mycobacterium tuberculosis
    • Barnes PF, Mehra V, Rivoire B, et al. Immunoreactivity of a 10-kDa antigen of Mycobacterium tuberculosis. J Immunol 148: 1835-1840, 1992.
    • (1992) J Immunol , vol.148 , pp. 1835-1840
    • Barnes, P.F.1    Mehra, V.2    Rivoire, B.3
  • 87
    • 0030991673 scopus 로고    scopus 로고
    • Partial activation of human T cells by peptide analogs on live APC: Induction of clonal anergy associated with protein tyrosine dephosphorylation
    • Matsushita S, Nishimura Y. Partial activation of human T cells by peptide analogs on live APC: induction of clonal anergy associated with protein tyrosine dephosphorylation. Hum Immunol 53: 73-80, 1997.
    • (1997) Hum Immunol , vol.53 , pp. 73-80
    • Matsushita, S.1    Nishimura, Y.2
  • 88
    • 0026646956 scopus 로고
    • Transcriptional downregulation of gap-junction proteins blocks junctional communication in human mammary tumor cell lines
    • Lee SW, Tomasetto C, Paul D, Keyomarsi K, Sager R. Transcriptional downregulation of gap-junction proteins blocks junctional communication in human mammary tumor cell lines. J Cell Biol 118: 1213-1221, 1992.
    • (1992) J Cell Biol , vol.118 , pp. 1213-1221
    • Lee, S.W.1    Tomasetto, C.2    Paul, D.3    Keyomarsi, K.4    Sager, R.5
  • 89
    • 0028807388 scopus 로고
    • Immunohistological detection of gap junctions in human lymphoid tissues: Connexin 43 in follicular dendritic and lymphoendothelial cells
    • Krenacs T, Rosendaal M. Immunohistological detection of gap junctions in human lymphoid tissues: connexin 43 in follicular dendritic and lymphoendothelial cells. J Histochem Cytochem 43: 1125-1137, 1995.
    • (1995) J Histochem Cytochem , vol.43 , pp. 1125-1137
    • Krenacs, T.1    Rosendaal, M.2
  • 90
    • 0027282044 scopus 로고
    • Bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
    • Boise LH, Gonzalez-Garcia M, Postema CE, et al. bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 74: 597-608, 1993.
    • (1993) Cell , vol.74 , pp. 597-608
    • Boise, L.H.1    Gonzalez-Garcia, M.2    Postema, C.E.3
  • 93
    • 0028922885 scopus 로고
    • Massive cell death of immature hematopoietic cells and neurons in Bcl-x-dericient mice
    • Motoyama N, Wang F, Roth KA, et al. Massive cell death of immature hematopoietic cells and neurons in Bcl-x-dericient mice. Science 267: 1506-1510, 1995.
    • (1995) Science , vol.267 , pp. 1506-1510
    • Motoyama, N.1    Wang, F.2    Roth, K.A.3
  • 95
    • 0028988325 scopus 로고
    • On the cellular basis of immunological T cell memory
    • Bruno L, Kirberg J, von Boehmer H. On the cellular basis of immunological T cell memory. Immunity 2: 37-43, 1995.
    • (1995) Immunity , vol.2 , pp. 37-43
    • Bruno, L.1    Kirberg, J.2    Von Boehmer, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.