Recombinant self-complementary adeno-associated virus serotype vector-mediated hematopoietic stem cell transduction and lineage-restricted, long-term transgene expression in a murine serial bone marrow transplantation model

Human Gene Therapy

Volumn 19, Issue 4, 2008, Pages 376-383

  Maina, Njeri ^a,b   Han, Zongchao ^a   Li, Xiaomiao ^a,c   Hu, Zhongbo ^a,c   Zhong, Li ^a,c   Bischof, Daniela ^b   Weigel Van Aken, Kirsten A ^a,c   Slayton, William B ^a,c   Yoder, Mervin C ^b   Srivastava, Arun ^a,c  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLOBIN; PARVOVIRUS VECTOR; SINGLE STRANDED ADENO ASSOCIATED VIRUS SEROTYPE 1 VECTOR; SINGLE STRANDED ADENO ASSOCIATED VIRUS SEROTYPE 10 VECTOR; SINGLE STRANDED ADENO ASSOCIATED VIRUS SEROTYPE 2 VECTOR; SINGLE STRANDED ADENO ASSOCIATED VIRUS SEROTYPE 7 VECTOR; SINGLE STRANDED ADENO ASSOCIATED VIRUS SEROTYPE 8 VECTOR;

ADENO ASSOCIATED VIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BETA THALASSEMIA; BONE MARROW TRANSPLANTATION; CELL LINEAGE; CONTROLLED STUDY; DNA SYNTHESIS; ENHANCER REGION; ERYTHROID CELL; GENE EXPRESSION; HEMATOPOIETIC STEM CELL; MALE; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PARVOVIRUS; PROMOTER REGION; REGULATOR GENE; SEROTYPE; SICKLE CELL ANEMIA; SIGNAL TRANSDUCTION; STEM CELL; TRANSGENE; VIRUS GENOME; VIRUS RECOMBINANT;

ANIMALS; BLOOD CELLS; BONE MARROW TRANSPLANTATION; CELL LINEAGE; DEPENDOVIRUS; DNA, RECOMBINANT; FEMALE; GENE EXPRESSION; GENETIC ENGINEERING; GENETIC VECTORS; HEMATOPOIETIC STEM CELLS; MALE; MICE; MICE, INBRED C57BL; MODELS, ANIMAL; TIME FACTORS; TRANSDUCTION, GENETIC; TRANSGENES;

ADENO-ASSOCIATED VIRUS; MURINAE; MUS; PARVOVIRUS;

EID: 41149124496     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.2007.143     Document Type: Article

References (43)

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