Effects of resveratrol on matrix metalloproteinase-9 expression in hepatoma cells

Journal of Chinese Integrative Medicine

Volumn 6, Issue 3, 2008, Pages 270-273

  Yu, Hai Bo ^a   Pan, Cheng En ^a   Wu, Wu Jun ^a   Zhao, Si Hai ^a   Zhang, Hui Feng ^b  

^a MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

^b HENAN PROVINCIAL PEOPLE'S HOSPITAL   (China)

Author keywords

Liver cancer; Matrix metalloproteinase 9; Resveratrol

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; GELATINASE B; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MESSENGER RNA; RESVERATROL;

ARTICLE; CANCER CELL CULTURE; CANCER CELL DESTRUCTION; CANCER INVASION; CELL PROLIFERATION; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; HEPATOMA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INHIBITION KINETICS; LIVER CELL CARCINOMA; METASTASIS INHIBITION; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TREATMENT OUTCOME; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CARCINOMA, HEPATOCELLULAR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; HUMANS; LIVER NEOPLASMS; MATRIX METALLOPROTEINASE 9; RNA, MESSENGER; STILBENES; TUMOR CELLS, CULTURED;

EID: 41149109107     PISSN: 16721977     EISSN: None     Source Type: Journal    
DOI: 10.3736/jcim20080310     Document Type: Article

References (13)

1. Huynh H. Overexpression of tumour suppressor retinoblastoma 2 protein (pRb2/p130) in hepatocellular carcinoma. Carcinogenesis. 2004; 25(8): 1485-1494.
2. Jang M, Cai L, Udeani GO, et al. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science. 1997; 275(5297): 218-220.
3. Yokota J. Tumor progression and metastasis. Carcinogenesis. 2000; 21(3): 497-503.
4. Sakamoto Y, Mafune K, Mori M, et al. Overexpression of MMP-9 correlates with growth of small hepatocellular carcinoma. Int J Oncol. 2000; 17(2): 237-243.
5. Zhong C, Guo RP, Shi M, et al. Expression and clinical significance of VEGF and MMP-9 in hepatocellular carcinoma. Ai Zheng. 2006; 25 (5): 599-603. Chinese with abstract in English.
6. Fu ZD, Cao Y, Wang KF, et al. Chemopreventive effect of resveratrol to cancer. Ai Zheng. 2004; 23(8): 869-873. Chinese with abstract in English.
7. Ahmad N, Adhami VM, Afaq F, et al. Resveratrol causes WAF-1/ p21-mediated G(1)-phase arrest of cell cycle and induction of apoptosis in human epidermoid carcinoma A431 cells. Clin Cancer Res. 2001; 7 (5): 1466-1473.
8. Surh YJ, Hurh YJ, Kang JY, et al. Resveratrol, an antioxidant present in red wine, induces apoptosis in human promyelocytic leukemia (HL-60) cells. Cancer Lett. 1999; 140(1-2): 1-10.
9. Sun CY, Hu Y, Guo T, et al. Resveratrol as a novel agent for treatment of multiple myeloma with matrix metalloproteinase inhibitory activity. Acta Pharmacol Sin. 2006; 27(11): 1447-1452.
10. Woo JH, Lim JH, Kim YH, et al. Resveratrol inhibits phorbol myristate acetate-induced matrix metalloproteinase-9 expression by inhibiting JNK and PKC delta signal transduction. Oncogene. 2004; 23(10): 1845-1853.
11. Huhtala P, Chow LT, Tryggvason K. Structure of the human type IV collagenase gene. J Biol Chem. 1990; 265(19): 11077-11082.
12. Li YT, Shen F, Liu BH, et al. Resveratrol inhibits matrix metalloproteinase-9 transcription in U937 cells. Acta Pharmacol Sin. 2003; 24(11): 1167-1171.
13. Ge H, Zhang JF, Guo BS, et al. Resveratrol inhibits expression of EMMPRIN from macrophages. Yao Xue Xue Bao. 2006; 41(7): 625-630. Chinese with abstract in English.