Resveratrol inhibits matrix metalloproteinase-9 transcription in U937 cells

Acta Pharmacologica Sinica

Volumn 24, Issue 11, 2003, Pages 1167-1171+1176

  Li, Yi Tang ^a   Shen, Fang ^a   Liu, Bai He ^a   Cheng, Gui Fang ^a  

^a PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

Matrix metalloproteinases; Phorbol esters; Resveratrol; Transcription factor AP 1; U937 cells

Indexed keywords

DEXAMETHASONE; GELATINASE B; MESSENGER RNA; PHORBOL 13 ACETATE 12 MYRISTATE; RESVERATROL; TRANSCRIPTION FACTOR AP 1;

ARTICLE; CELL STRAIN U937; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; FETAL CALF SERUM; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ZYMOGRAPHY;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DEXAMETHASONE; HUMANS; MATRIX METALLOPROTEINASE 9; RNA, MESSENGER; STILBENES; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION, GENETIC; U937 CELLS;

EID: 0242557604     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Glenn AR Doyle, Richard A, Pierce, William C. Parks. Transcriptional induction of collagenase-1 in differentiated monocyte-like (U937) cells is regulated by AP-1 and an upstream C/EBP-β site. J Biol Chem 1997; 272: 11840-9.
2. Nguyen M, Arkell J, Jackson CJ. Human endothelial gelatinases and angiogenesis. Int J Biochem Cell Biol 2001; 33: 960-70.
3. Holmes-McNary M, Baldwin AS Jr. Chemopreventive properties of trans-resveratrol are associated with inhibition of activation of the IkappaB kinase. Cancer Res 2000; 60: 3477-83.
4. Ulpu K. Saarialho-Kere, Howard G. Welgus, William C. Parks. Distinc mechanisms regulat interstitial collagenase and 92-kDa gelatinase expression in human monocytic-like cells exposed to bacterial endotoxin. J Biol Chem 1993; 268: 17354-61.
5. Nagaoka I, Hirota S. Increased expression of matrix metalloproteinase-9 in neutrophils in glycogen-induced peritoneal inflammation of guinea pigs. Inflamm Res 2000; 49: 55-62.
6. Li LC, Shen F, Hou Q, Cheng GF. Inhibitory effect and mechanism of action of sanggenon C on human polymorphonuclear leukocyte adhesion to human synovial cells. Acta Pharmacol Sin 2002; 23: 138-42.
7. Demeule M, Brossard M, Page M, Gingras D, Beliveau R. Matrix metalloproteinase inhibition by green tea catechins. Biochim Biophys Acta 2000; 16: 51-60.
8. Subbaramaiah K, Chung WJ, Michaluart P, Telang N, Tanabe T, Inoue H, et al. Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells. J Biol Chem 1998; 273: 21875-82.