Degraded Collagenase Deteriorates Islet Viability

Transplantation Proceedings

Volumn 40, Issue 2, 2008, Pages 370-371

  Brandhorst, H ^a   Raemsch Guenther, N ^b   Raemsch, C ^c   Friedrich, O ^c   Kurfuerst, M ^c   Korsgren, O ^a   Brandhorst, D ^a  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^b SERVA Electrophoresis GmbH   (Germany)

^c Nordmark Arzneimittel GmbH and Co KG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE; COLLAGENASE TYPE 1; COLLAGENASE TYPE 2; ENZYME; NEUTRAL PROTEINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL ISOLATION; CELL TRANSPLANTATION; CELL VIABILITY; CHROMATOGRAPHY; CONTROLLED STUDY; DIABETES MELLITUS; ENZYMATIC DEGRADATION; ENZYME PURIFICATION; FRAGMENTATION REACTION; GRAFT RECIPIENT; HYPERGLYCEMIA; IN VITRO STUDY; ISOMER; MOUSE; NONHUMAN; NUDE MOUSE; PANCREAS ISLET CELL; PANCREAS ISLET CELL FUNCTION; PRIORITY JOURNAL; RAT; STATISTICAL SIGNIFICANCE; WEIGHT GAIN;

ANIMALS; CELL SURVIVAL; COLLAGENASES; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; MATRIX METALLOPROTEINASE 8; RATS; TISSUE AND ORGAN HARVESTING; TREATMENT OUTCOME;

EID: 41049101247     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2008.01.013     Document Type: Article

References (5)

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3. Jahr H., Hussmann B., Eckhardt T., et al. Successful single donor islet allotransplantation in the streptozotocin diabetes rat model. Cell Transplant 11 (2002) 513
4. Balamurugan A.N., He J., Guo F., et al. Harmful delayed effects of exogenous isolation enzymes on isolated human islets: relevance to clinical transplantation. Am J Transplant 5 (2005) 2671
5. Vargas F., Julian J.F., Liamazares J.F., et al. Engraftment of islets obtained by collagenase and Liberase in diabetic rats: a comparative study. Pancreas 23 (2001) 406