Supercritical CO2 antisolvent precipitation of polymer networks of l-PLA, PMMA and PMMA/PCL blends for biomedical applications

European Polymer Journal

Volumn 44, Issue 4, 2008, Pages 1081-1094

  Vega González, Arlette ^a   Subra Paternault, Pascale ^a   López Periago, Ana M ^b   García González, Carlos A ^b   Domingo, Concepción ^b  

^a UNIVERSITÉ PARIS 13   (France)

^b INSTITUT DE CIÈNCIA DE MATERIALS DE BARCELONA ICMAB CSIC   (Spain)

Author keywords

Blends; Fibers; l PLA; PCL; PMMA; Supercritical CO2

Indexed keywords

BIODEGRADABLE POLYMERS; BIOPOLYMERS; HOMOPOLYMERIZATION; INTERPENETRATING POLYMER NETWORKS; PRECIPITATION (CHEMICAL);

ANTISOLVENT PRECIPITATION; ANTISOLVENT SUPERCRITICAL TECHNIQUES;

CARBON DIOXIDE;

EID: 41049085140     PISSN: 00143057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eurpolymj.2008.01.009     Document Type: Article

References (49)

1. Hutmacher D.W. Scaffolds in tissue engineering bone and cartilage. Biomaterials 21 (2000) 2529-2543
2. Shin H., Jo S., and Mikos A.G. Biomimetic materials for tissue engineering. Biomaterials 24 (2003) 4353-4364
3. Whang K., Thomas C.H., Healy K.E., and Nuber G. A novel method to fabricate bioabsorbable scaffolds. Polymer 36 (1995) 837-842
4. Karageorgiou V., and Kaplan D. Porosity of 3D biomaterial scaffolds and osteogenesis. Biomaterials 26 (2005) 5474-5491
5. Moroni L., de Wijn J.R., and Blitterswijk C.A. 3D fiber-deposited scaffolds for tissue engineering: influence of pores geometry and architecture on dynamic mechanical properties. Biomaterials 27 (2006) 974-985
6. Tuzlakoglu K., Bolgen N., Salgado A.J., Gomes M.E., Piskin E., and Reis R.L. Nano- and micro-fiber combined scaffolds: a new architecture for bone tissue engineering. J Mater Sci 16 (2005) 1099-1104
7. Baldwin S.P., and Saltzman W.M. Materials for protein delivery in tissue engineering. Adv Drug Deliv Rev 33 (1998) 71-86
8. Vert M., Li M.S., Spenlehauer G., and Guerin P. Bioresorbability and biocompability of aliphatic polyesters. J Mater Sci 3 (1992) 432-446
9. Drotleff S., Lungwitz U., Breunig M., Dennis A., Blunk T., Tessmar J., et al. Biomimetic polymers in pharmaceutical and biomedical sciences. Eur J Pharma Biopharma 58 (2004) 385-407
10. Downes S., Archer R.S., Kayser M.V., Patel M.P., and Braden M. The regeneration of cartilage using a new polymer system. J Mater Sci: Mater Med 5 (1994) 88-95
11. Hentze H.P., and Antonietti M. Porous polymers and resins for biotechnological and biomedical applications. Rev Molec Biotechnol 90 (2002) 27-53
12. Barbetta A. Scaffolds based on biopolymeric foams. Adv Funct Mater 15 (2005) 118-123
13. Yeong W.Y., Chua C.K., Leong K.F., and Chandrasekaran M. Rapid prototyping in tissue engineering: challenges and potential. Trends Biotechnol 22 12 (2004) 643-652
14. Nalawade S.P., Picchioni F., and Janssen L.P.B.M. Supercritical carbon dioxide as a green solvent for processing polymer melts: processing aspects and applications. Prog Polym Sci 31 (2006) 19-43
15. Fleming S., and Kazarian S.G. In: Kemmere M.F., and Meyer Th. (Eds). Supercritical carbon dioxide in polymer reaction engineering (2005), Wiley-VCH, New York 205
16. Cooper A.I. Polymer synthesis and processing using supercritical carbon dioxide. J Mater Chem 10 (2000) 207-234
17. Cooper A.I. Porous materials and supercritical fluids. Adv Mater 15 13 (2003) 1049-1059
18. 2 applications in the processing of polymers. Ind Eng Chem Res 42 (2003) 6431-6456
19. Quirk R.A., France R.M., Shakesheff K.M., and Howdle S.M. Supercritical fluid technologies and tissue engineering scaffolds. Curr Opin Solid State Mater Sci 8 (2004) 313-321
20. 2 plus cosolvent: solubility measurements and process assessment. J Appl Polym Sci 90 (2003) 3652-3659
21. Silva M.M.C.G., Cyster L.A., Barry J.J.A., Yang X.B., Oreffo R.O.C., Grant D.M., et al. The effect of anisotropic architecture on cell and tissue infiltration into tissue engineering scaffolds. Biomaterials 27 (2006) 5909-5917
22. Mathieu LM, Montjovent MO, Bourvan PE, Pioletti DP, Manson JAE. In: Bioresorbable composites prepared by supercritical fluid foaming. Wiley Periodicals, Inc.; 2005.
23. Elvassore N, Kikic I. In: Pharmaceutical processing with supercritical fluids, vol. 9. Industrial Chemistry Library; 2001. p. 612-625.
24. Sheridan M.H., Shea L.D., Peters M.C., and Mooney D.J. Bioabsorbable polymer scaffolds for tissue engineering capable of sustained growth factor delivery. J Control Release 64 (2000) 91-102
25. 2: a model-component study towards producing controlled-release drugs. J Supercrit Fluids 38 (2006) 119-128
26. Nauman E.B., Ariyapadi M.V., Alsara M.V., Grocela T.A., Furno J.S., Liu S.H., et al. Compositional quenching: a process for forming polymer-in-polymer microdispersions and continuous networks. Chem Eng Commun 66 (1988) 29-33
27. Reverchon E., Della Porta G., De Rosa I., Subra P., and Letourneur D. Supercritical antisolvent micronization of some biopolymers. J Supercrit Fluids 18 (2000) 239-245
28. Reverchon E., and Antonacci A. Polymer microparticles production by supercritical assisted atomization. J Supercrit Fluids 39 (2007) 444-452
29. Mawson S., Kanakia S., and Johnston P. Coaxial nozzle for control of particle morphology in precipitation with a compressed fluid antisolvent. J Appl Polym Sci 64 (1997) 2105-2118
30. 2 in a mixed solvent. Ind Eng Chem Res 40 (2001) 795-800
31. Yeo S.-D., and Kiran E. Formation of polymer particles with supercritical fluids: a review. J Supercrit Fluids 34 (2005) 287-298
32. Brunauer S., Mikhail R.S., and Boer E.E. Investigations of a complete pore structure analysis: I. Analysis of micropores. J Colloid Interface Sci 26 (1968) 45-53
33. Abraham G.A., Gallardo A., Motta A., Migliaresi C., and San Román J. Microheterogeneous polymer systems prepared by suspension polymerization of methyl methacrylate in the presence of poly(e-caprolactone). Macromol Mater Eng 282 (2000) 44-50
34. Luna-Bárcenas G., Kanakia S.K., Sánchez I.C., and Johnston K.P. Semicrystalline microfibrils and hollow fibers by precipitation with a compressed-fluid antisolvent. Polymer 36 16 (1995) 3173-3182
35. Dixon D.J., and Johnston K.P. Formation of microporous polymer fibers and oriented fibrils by precipitation with a compressed fluid antisolvent. J Appl Polym Sci 50 (1993) 1929-1942
36. Mawson S., Kanakia S., and Johnston K.P. Coaxial nozzle for control of particle morphology in precipitation with a compressed fluid antisolvent. Polymer 38 12 (1997) 2957-2967
37. Bleich J., Kleinebudde P., and Müller B.W. Influence of gas density and pressure on microparticles produced with the ASES process. Int J Pharm 6 (1994) 77-84
38. 2 antisolvent techniques. Biotech Bioeng 73 (2001) 449-457
39. Randolph T.W., Randolph A.D., Mebes M., and Yeung S. Sub-micrometer-sized biodegradable particles of poly (l-lactic acid) via the gas antisolvent spray precipitation process. Biotech Prog 9 (1993) 429-435
40. Czerwonatis N., and Eggers R. Disintegration of liquid jets and drop drag coefficients in pressurized nitrogen and carbon dioxide. Chem Eng Technol 24 (2001) 619-624
41. Dukhin S.S., Zhu C., Dave R., Pfeffer R., Luo J.J., Chavez F., et al. Dynamic interfacial tension near critical point of a solvent-antisolvent mixture and laminar jet stabilization. Coll Surf: A Phys Eng Asp 229 (2003) 181-199
42. Rantakylä M., Jäntti M., Aaltonen O., and Hurme M. The effect of initial drop size on particle size in the supercritical antisolvent precipitation (SAS) technique. J Supercrit Fluids 24 (2002) 251-263
43. Bodmeier R., Wang H., Dixon D.J., Mawson S., and Johnston K.P. Polymeric microspheres prepared by spraying into compressed carbon dioxide. Pharm Res 12 8 (1995) 1211-1217
44. Thies J., and Müller B.W. Size controlled production of biodegradable microparticles with supercritical gases. Eur J Pharm Biopharm 45 (1998) 67-74
45. Subra P., Berroy P., Saurina J., and Domingo C. Influence of expansion conditions on the characteristics of cholesterol crystals analyzed by statistical design. J Supercrit Fluids 31 (2004) 313-322
46. Vega-González A., Domingo C., Elvira C., and Subra P. Precipitation of PMMA/PCL blends using supercritical carbon dioxide. J Appl Polym Sci 91 (2004) 2422-2426
47. Kazarian S., and Chan K.L.A. FTIR imaging of polymeric materials under high-pressure carbon dioxide. Macromolecules 37 (2004) 579-584
48. Condo P.D., and Johnston K.P. Retrograde vitrification of polymer with compressed fluid diluents: experimental confirmation. Macromolecules 25 (1992) 6730-6732
49. 2 mixtures at elevated pressures. J Polym Sci: Part B 25 (1987) 2497-2502