Identification of plasma membrane autoantigens in autoimmune hepatitis type 1 using a proteomics tool

Hepatology

Volumn 47, Issue 3, 2008, Pages 937-948

  Tahiri, Fatima ^a,b   Le Naour, François ^c   Huguet, Stéphanie ^a,b,d   Lai Kuen, René ^e   Samuel, Didier ^a,b,g   Johanet, Catherine ^d,f   Saubamea, Bruno ^e   Tricottet, Viviane ^e   Duclos Vallee, Jean Charles ^a,b,g   Ballot, Eric ^a,b,d,g  

^a INSERM   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c INSTITUT ANDRÉ LWOFF   (France)

^d HÔPITAL SAINT ANTOINE   (France)

^e UNIVERSITÉ PARIS DESCARTES   (France)

^f SORBONNE UNIVERSITÉ   (France)

^g HÔPITAL PAUL BROUSSE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINASE; AUTOANTIBODY; AUTOANTIGEN; CELL ANTIBODY; CYTOKERATIN 18; CYTOKERATIN 8; HEAT SHOCK PROTEIN 60; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; LIVER ENZYME; MEMBRANE ANTIGEN; VALOSIN CONTAINING PROTEIN; MEMBRANE PROTEIN;

ADOLESCENT; ADULT; AGED; ALCOHOL LIVER DISEASE; ANTIBODY SPECIFICITY; ANTIGEN DETECTION; ANTIGEN SPECIFICITY; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNE HEPATITIS; BLOOD DONOR; CELL MEMBRANE; CHRONIC HEPATITIS; CHRONIC LIVER DISEASE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HEPATITIS C; HUMAN; IMMUNOBLOTTING; IMMUNOELECTRON MICROSCOPY; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOREACTIVITY; ION TRAP MASS SPECTROMETRY; LIVER CELL; MAJOR CLINICAL STUDY; MALE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEOMICS; RHEUMATOID ARTHRITIS; SCHOOL CHILD; SERUM; SYSTEMIC DISEASE; SYSTEMIC LUPUS ERYTHEMATOSUS; TWO DIMENSIONAL ELECTROPHORESIS; WESTERN BLOTTING; BLOOD; CHILD; IMMUNOLOGY; ISOLATION AND PURIFICATION; MIDDLE AGED;

ADOLESCENT; ADULT; AGED; AUTOANTIBODIES; AUTOANTIGENS; CELL MEMBRANE; CHILD; FEMALE; HEPATITIS, AUTOIMMUNE; HEPATOCYTES; HUMANS; IMMUNOBLOTTING; MALE; MEMBRANE PROTEINS; MIDDLE AGED; PROTEOMICS;

EID: 40949149443     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.22149     Document Type: Article

References (53)

1. Czaja AJ. Autoantibodies in autoimmune liver disease. Adv Clin Chem 2005;40:127-164.
2. Zeniya M. Autoantibodies to hepatocyte plasma membrane antigens in autoimmune hepatitis: old and new subjects; what do we need? J Gastroenterol 2000;35:252-253.
3. Al-Khalidi JA, Czaja AJ. Current concepts in the diagnosis, pathogenesis, and treatment of autoimmune hepatitis. Mayo Clin Proc 2001;76:1237-1252.
4. Yamauchi K, Yamaguchi N, Furukawa T, Takatsu K, Nakanishi T, Ishida K, et al. A murine model of acute liver injury induced by human monoclonal autoantibody. HEPATOLOGY 2005;42:149-155.
5. Mizutani T, Shinoda M, Tanaka Y, Kuno T, Hattori A, Usui T, et al. Autoantibodies against CYP2D6 and other drug-metabolizing enzymes in autoimmune hepatitis type 2. Drug Metab Rev 2005;37:235-252.
6. Sasaki M, Yamauchi K, Tokushige K, Isono E, Komatsu T, Zeniya M, et al. Clinical significance of autoantibody to hepatocyte membrane antigen in type 1 autoimmune hepatitis. Am J Gastroenterol 2001;96:846-851.
7. Toda G, Ikeda Y, Kashiwagi M, Iwamori M, Oka H. Hepatocyte plasma membrane glycosphingolipid reactive with sera from patients with autoimmune chronic active hepatitis: its identification as sulfatide. HEPATOLOGY 1990;12:664-670.
8. Tokushige K, Hasegawa K, Hirose S, Shirai T, Yamauchi K, Obata H. Liver cell-membrane specific antibodies in autoimmune hepatitis patients detected by flow cytometry. Int Hepatol Commun 1993;1:41-47.
9. Swanson NR, Reed WD, Yarred LJ, Shilkin KB, Joske RA. Autoantibodies to isolated human hepatocyte plasma membranes in chronic active hepatitis. II. Specificity of antibodies. HEPATOLOGY 1990;11:613-621.
10. Hopf U, Jahn HU, Moller B, Stemerowicz R, Wittenbrink C, Klein R, et al. Liver membrane antibodies (LMA) recognize a 26-kD protein on the hepatocellular surface. Clin Exp Immunol 1990;79:54-61.
11. Matsuo I, Ikuno N, Omagari K, Kinoshita H, Oka M, Yamaguchi H, et al. Autoimmune reactivity of sera to hepatocyte plasma membrane in type 1 autoimmune hepatitis. J Gastroenterol 2000;35:226-234.
12. Humphery-Smith I, Cordwell SJ, Blackstock WP. Proteome research: complementarity and limitations with respect to the RNA and DNA worlds. Electrophoresis 1997;18:1217-1242.
13. Verrills NM. Clinical proteomics: present and future prospects. Clin Biochem Rev 2006;27:99-116.
14. Dotzlaw H, Eggert M, Neeck G, Schulz M. Spots, blots, peaks and chips: proteomic approaches in autoimmune diseases. Curr Pharm Des 2006;12: 3699-3706.
15. Ballot E, Bruneel A, Labas V, Johanet C. Identification of rat targets of anti-soluble liver antigen autoantibodies by serologic proteome analysis. Clin Chem 2003;49:634-643.
16. Canelle L, Bousquet J, Pionneau C, Deneux L, Imam-Sghiouar N, Caron M, et al. An efficient proteomics-based approach for the screening of autoantibodies. J Immunol Methods 2005;299:77-89.
17. Alvarez F, Berg PA, Bianchi FB, Bianchi L, Burroughs AK, Cancado EL, et al. International Autoimmune Hepatitis Group Report: review of criteria for diagnosis of autoimmune hepatitis. J Hepatol 1999;31:929-938.
18. Hubbard AL, Wall DA, Ma A. Isolation of rat hepatocyte plasma membranes. I. Presence of the three major domains. J Cell Biol 1983;96:217-229.
19. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:680-685.
20. Gorg A, Weiss W, Dunn MJ. Current two-dimensional electrophoresis technology for proteomics. Proteomics 2004;4:3665-3685.
21. Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Biotechnology 1992;24:145-149.
22. Shevchenko A, Wilm M, Vorm O, Mann M. Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal Chem 1996;68: 850-858.
23. Ducret A, Van Oostveen I, Eng JK, Yates JR 3rd, Aebersold R. High throughput protein characterization by automated reverse-phase chromatography/electrospray tandem mass spectrometry. Protein Sci 1998;7:706-719.
24. Kimura M, Tatsumi KI, Tada H, Ikemoto M, Fukuda Y, Kaneko A, et al. Enzyme immunoassay for autoantibodies to human liver-type arginase and its clinical application. Clin Chem 2000;46:112-117.
25. Castell M. Cytoskeletal autoantibodies. In Peter JB, Shoenfeld Y, eds. Autoantibodies, 1st ed. Netherlands: Elsevier; 1996:217-226.
26. Kerner MJ, Naylor DJ, Ishihama Y, Maier T, Chang HC, Stines AP, et al. Proteome-wide analysis of chaperonin-dependent protein folding in Escherichia coli. Cell 2005;122:209-220.
27. Ballar P, Shen Y, Yang H, Fang S. The role of a novel p97/valosin-containing protein-interacting motif of gp78 in endoplasmic reticulum-associated degradation. J Biol Chem 2006;281:35359-35368.
28. Prince T, Shao J, Matts RL, Hartson SD. Evidence for chaperone heterocomplexes containing both Hsp90 and VCP. Biochem Biophys Res Commun 2005;331:1331-1337.
29. Foster LJ, de Hoog CL, Zhang Y, Zhang Y, Xie X, Mootha VK, et al. A mammalian organelle map by protein correlation profiling. Cell 2006;125: 187-199.
30. Zhang L, Wang X, Peng X, Wei Y, Cao R, Liu Z, et al. Immunoaffinity purification of plasma membrane with secondary antibody superparamagnetic beads for proteomic analysis. J Proteome Res 2007;6:34-43.
31. Sostaric E, Georgiou AS, Wong CH, Watson PF, Holt WV, Fazeli A. Global profiling of surface plasma membrane proteome of oviductal epithelial cells. J Proteome Res 2006;5:3029-3037.
32. Lancaster GI, Febbraio MA. Exosome-dependent trafficking of HSP70: a novel secretory pathway for cellular stress proteins. J Biol Chem 2005;280: 23349-23355.
33. Shin BK, Wang H, Yim AM, Le Naour F, Brichory F, Jang JH, et al. Global profiling of the cell surface proteome of cancer cells uncovers an abundance of proteins with chaperone function. J Biol Chem 2003;278: 7607-7616.
34. Harada M, Kimura G, Nomoto K. Heat shock proteins and the antitumor T cell response. Biotherapy 1998;10:229-235.
35. Tanudji M, Hevi S, Chuck SL. Improperly folded green fluorescent protein is secreted via a non-classical pathway. J Cell Sci 2002;115:3849-3857.
36. Wells MJ, Hatton MW, Hewlett B, Podor TJ, Sheffield WP, Blajchman MA. Cytokeratin 18 is expressed on the hepatocyte plasma membrane surface and interacts with thrombin-antithrombin complexes. J Biol Chem 1997;272:28574- 28581.
37. Gonias SL, Hembrough TA, Sankovic M. Cytokeratin 8 functions as a major plasminogen receptor in select epithelial and carcinoma cells. Front Biosci 2001;6:D1403-D1411.
38. Bocharov AV, Vishnyakova TG, Baranova IN, Remaley AT, Patterson AP, Eggerman TL. Heat shock protein 60 is a high-affinity high-density lipoprotein binding protein. Biochem Biophys Res Commun 2000;277: 228-235.
39. Gehrmann M, Brunner M, Pfister K, Reichle A, Kremmer E, Multhoff G. Differential up-regulation of cytosolic and membrane-bound heat shock protein 70 in tumor cells by anti-inflammatory drugs. Clin Cancer Res 2004;10:3354-3364.
40. Kovar J, Stybrova H, Novak P, Ehrlichova M, Truksa J, Koc M, et al. Heat shock protein 90 recognized as an iron-binding protein associated with the plasma membrane of HeLa cells. Cell Physiol Biochem 2004;14:41-46.
41. Reyes-Del Valle J, Chavez-Salinas S, Medina F, Del Angel RM. Heat shock protein 90 and heat shock protein 70 are components of dengue virus receptor complex in human cells. J Virol 2005;79:4557-4567.
42. Triantafilou M, Triantafilou K. Heat-shock protein 70 and heat-shock protein 90 associate with Toll-like receptor 4 in response to bacterial lipopolysaccharide. Biochem Soc Trans. 2004;32:636-639.
43. Mafune N, Ideta N, Watabe H, Nagura H, Kobayashi K. Occurrence of cytotoxic autoantibody in rabbits by immunization with heterologous liver arginase: a possible implication in the mechanism of the autoimmune liver diseases. Clin Exp Immunol 1985;59:123-131.
44. Hubbard AL, Ma A. Isolation of rat hepatocyte plasma membranes. II. Identification of membrane-associated cytoskeletal proteins. J Cell Biol 1983;96:230-239.
45. Hajoui O, Martin S, Alvarez F. Study of antigenic sites on the asialoglycoprotein receptor recognized by autoantibodies. Clin Exp Immunol 1998; 113:339-345.
46. Whittingham S, Mackay IR. Smooth muscle antibodies. In: Peter JB, Shoenfeld Y, eds. Autoantibodies, 1st ed. Netherlands: Elsevier Sciences BV; 1996:767-773.
47. Morhsed SA, Parveen S, NishiokaM. Antibodies to cytoskeleton antigen in autoimmune liver diseases. In: Krawitt EL, Wiesner RH, Nishioka M, eds. Autoimmune liver diseases, 2nd ed. Netherlands: Elsevier Science B.V; 1998:217-256.
48. Shingai R, Maeda T, Onishi S, Yamamoto Y. Autoantibody against 70 kD heat shock protein in patients with autoimmune liver diseases. J Hepatol 1995;23:382-390.
49. Miyachi K, Hitano Y, Horigome T, Mimori T, Miyakawa H, Onozuka Y, et al. Autoantibodies from primary biliary cirrhosis patients with anti-p95c antibodies bind to recombinant p97/VCP and inhibit in vitro nuclear envelope assembly. Clin Exp Immunol. 2004;136:568-573.
50. Sherer Y, Shoenfeld Y. Idiotypic network dysregulation: a common etiopathogenesis of diverse autoimmune diseases. Appl Biochem Biotechnol 2000;83:155-162.
51. Brickman CM, Shoenfeld Y. The mosaic of autoimmunity. Scand J Clin Lab Invest 2001;235(Suppl):3-15.
52. Gilbert S, Loranger A, Marceau N. Keratins modulate c-Flip/extracellular signal-regulated kinase 1 and 2 antiapoptotic signaling in simple epithelial cells. Mol Cell Biol 2004;24:7072-7081.
53. Purcell AW, Todd A, Kinoshita G, Lynch TA, Keech CL, Gething MJ, et al. Association of stress proteins with autoantigens: a possible mechanism for triggering autoimmunity? Clin Exp Immunol 2003;132:193-200.