-
1
-
-
33747197773
-
New treatment approaches in metastatic renal cell carcinoma
-
Sep;
-
Mancuso A, Sternberg CN. New treatment approaches in metastatic renal cell carcinoma. Curr Opin Urol 2006 Sep; 16 (5): 337-41
-
(2006)
Curr Opin Urol
, vol.16
, Issue.5
, pp. 337-341
-
-
Mancuso, A.1
Sternberg, C.N.2
-
2
-
-
33845578926
-
Kidney cancer therapy: New perspectives and avenues
-
Alexandrescu DT, Dasanu CA. Kidney cancer therapy: new perspectives and avenues. Expert Opin Pharmacother 2006; 7 (18): 2481-93
-
(2006)
Expert Opin Pharmacother
, vol.7
, Issue.18
, pp. 2481-2493
-
-
Alexandrescu, D.T.1
Dasanu, C.A.2
-
3
-
-
34250332941
-
Common and uncommon histologic subtypes of renal cell carcinoma: Imaging spectrum with pathologic correlation
-
Prasad SR, Humphrey PA, Catena JA, et al. Common and uncommon histologic subtypes of renal cell carcinoma: imaging spectrum with pathologic correlation. Radiographics 2006; 26 (6): 1795-810
-
(2006)
Radiographics
, vol.26
, Issue.6
, pp. 1795-1810
-
-
Prasad, S.R.1
Humphrey, P.A.2
Catena, J.A.3
-
4
-
-
33644840580
-
Targeted therapy for metastatic renal cell carcinoma
-
Mar 13;
-
Patel PH, Chaganti RS, Motzer RJ. Targeted therapy for metastatic renal cell carcinoma. Br J Cancer 2006 Mar 13; 94 (5): 614-9
-
(2006)
Br J Cancer
, vol.94
, Issue.5
, pp. 614-619
-
-
Patel, P.H.1
Chaganti, R.S.2
Motzer, R.J.3
-
5
-
-
33846369848
-
Anti-angiogenic therapy in the treatment of advanced renal cell cancer
-
Board RE, Feb;
-
Board RE, Thistlethwaite FC, Hawkins RE. Anti-angiogenic therapy in the treatment of advanced renal cell cancer. Cancer Treat Rev 2007 Feb; 33 (1): 1-8
-
(2007)
Cancer Treat Rev
, vol.33
, Issue.1
, pp. 1-8
-
-
Thistlethwaite, F.C.1
Hawkins, R.E.2
-
6
-
-
34249941592
-
Advanced renal cell carcinoma: Current and emerging management strategies
-
Escudier B. Advanced renal cell carcinoma: current and emerging management strategies. Drugs 2007; 67 (9): 1257-64
-
(2007)
Drugs
, vol.67
, Issue.9
, pp. 1257-1264
-
-
Escudier, B.1
-
7
-
-
33845342538
-
Targeted anti-cancer therapies for renal cancer
-
Amato RJ, Jac J. Targeted anti-cancer therapies for renal cancer. Drugs 2006; 66 (17): 2161-71
-
(2006)
Drugs
, vol.66
, Issue.17
, pp. 2161-2171
-
-
Amato, R.J.1
Jac, J.2
-
8
-
-
34047222738
-
Recent progress in the management of advanced renal cell carcinoma
-
Mar;
-
Garcia JA, Rini BI. Recent progress in the management of advanced renal cell carcinoma. CA Cancer J Clin 2007 Mar; 57 (2): 112-25
-
(2007)
CA Cancer J Clin
, vol.57
, Issue.2
, pp. 112-125
-
-
Garcia, J.A.1
Rini, B.I.2
-
9
-
-
40949131920
-
-
Canada AE, Kirkali Z. Current management of renal cell carcinoma and targeted therapy. Urol J 2006 Winter; 3 (1): 1-14
-
Canada AE, Kirkali Z. Current management of renal cell carcinoma and targeted therapy. Urol J 2006 Winter; 3 (1): 1-14
-
-
-
-
10
-
-
0037379172
-
Prediction of progression after radical nephrectomy for patients with clear cell renal cell carcinoma: A stratification tool for prospective clinical trials
-
Leibovich BC, Blute ML, Cheville JC, et al. Prediction of progression after radical nephrectomy for patients with clear cell renal cell carcinoma: a stratification tool for prospective clinical trials. Cancer 2003; 97 (7): 1663-71
-
(2003)
Cancer
, vol.97
, Issue.7
, pp. 1663-1671
-
-
Leibovich, B.C.1
Blute, M.L.2
Cheville, J.C.3
-
11
-
-
33947288597
-
Vascular endothelial growth factor-targeted therapy in renal cell carcinoma: Current status and future directions
-
Feb 15;
-
Rini BI. Vascular endothelial growth factor-targeted therapy in renal cell carcinoma: current status and future directions. Clin Cancer Res 2007 Feb 15; 13 (4): 1098-106
-
(2007)
Clin Cancer Res
, vol.13
, Issue.4
, pp. 1098-1106
-
-
Rini, B.I.1
-
12
-
-
40349090585
-
Targeted therapy for renal cell carcinoma: A new treatment paradigm
-
Jul;
-
Hutson TE. Targeted therapy for renal cell carcinoma: a new treatment paradigm. Proc (Bayl Univ Med Cent) 2007 Jul; 20 (3): 244-8
-
(2007)
Proc (Bayl Univ Med Cent)
, vol.20
, Issue.3
, pp. 244-248
-
-
Hutson, T.E.1
-
13
-
-
33646529427
-
The place of VEGF inhibition in the current management of renal cell carcinoma
-
May 8;
-
Nathan P, Chao D, Brock C, et al. The place of VEGF inhibition in the current management of renal cell carcinoma. Br J Cancer 2006 May 8; 94 (9): 1217-20
-
(2006)
Br J Cancer
, vol.94
, Issue.9
, pp. 1217-1220
-
-
Nathan, P.1
Chao, D.2
Brock, C.3
-
14
-
-
40949093240
-
-
Sutent 12.5 mg, 25 mg and 50 mg hard capsules. Summary of product characteristics. Sandwich: Pfizer Limited, 2007 Sep
-
Sutent 12.5 mg, 25 mg and 50 mg hard capsules. Summary of product characteristics. Sandwich: Pfizer Limited, 2007 Sep
-
-
-
-
15
-
-
40949094110
-
-
Sutent (sunitinib malate) capsules, oral [prescribing information]. New York: Pfizer Labs., 2007 Oct
-
Sutent (sunitinib malate) capsules, oral [prescribing information]. New York: Pfizer Labs., 2007 Oct
-
-
-
-
16
-
-
40949164786
-
-
Nexavar 200mg film-coated tablets. Summary of product characteristics. Newbury: Bayer plc, 2007 Oct
-
Nexavar 200mg film-coated tablets. Summary of product characteristics. Newbury: Bayer plc, 2007 Oct
-
-
-
-
17
-
-
40949083154
-
-
Nexavar (sorafenib) tablets 200 mg [prescribing information]. West Haven (CT): Bayer Pharmaceuticals Corporation, 2007 Oct
-
Nexavar (sorafenib) tablets 200 mg [prescribing information]. West Haven (CT): Bayer Pharmaceuticals Corporation, 2007 Oct
-
-
-
-
18
-
-
40949115581
-
-
ToriselTM Kit (temsirolimus) injection, for intravenous infusion only. Prescribing information. Philadelphia (PA): Wyeth Pharmaceuticals Inc., 2007 May
-
ToriselTM Kit (temsirolimus) injection, for intravenous infusion only. Prescribing information. Philadelphia (PA): Wyeth Pharmaceuticals Inc., 2007 May
-
-
-
-
19
-
-
33644998656
-
Bevacizumab: A review of its use in advanced colorectal cancer, breast cancer, and NSCLC
-
Lyseng-Williamson KA, Robinson DM. Bevacizumab: a review of its use in advanced colorectal cancer, breast cancer, and NSCLC. Am J Cancer 2006; 5 (1): 43-60
-
(2006)
Am J Cancer
, vol.5
, Issue.1
, pp. 43-60
-
-
Lyseng-Williamson, K.A.1
Robinson, D.M.2
-
20
-
-
15344340324
-
Bevacizumab: Antiangiogenic cancer therapy
-
Culy C. Bevacizumab: antiangiogenic cancer therapy. Drugs Today 2005; 41 (1): 23-36
-
(2005)
Drugs Today
, vol.41
, Issue.1
, pp. 23-36
-
-
Culy, C.1
-
21
-
-
40949090684
-
-
Avastin (bevacizumab). Prescribing information. San Francisco (CA): Genentech Inc., 2006 Oct
-
Avastin (bevacizumab). Prescribing information. San Francisco (CA): Genentech Inc., 2006 Oct
-
-
-
-
22
-
-
40949115582
-
-
Avastin 25 mg/mL concentrate for solution for infusion. Summary of product characteristics. Welwyn Garden City: Roche Products Limited, 2008
-
Avastin 25 mg/mL concentrate for solution for infusion. Summary of product characteristics. Welwyn Garden City: Roche Products Limited, 2008
-
-
-
-
24
-
-
34547918788
-
Bevacizumab: In first-line treatment of metastatic breast cancer
-
Scott LJ. Bevacizumab: in first-line treatment of metastatic breast cancer. Drugs 2007; 67 (12): 1793-9
-
(2007)
Drugs
, vol.67
, Issue.12
, pp. 1793-1799
-
-
Scott, L.J.1
-
25
-
-
4544270422
-
Bevacizumab: In the treatment of colorectal cancer
-
Croom KF, Foster RH. Bevacizumab: in the treatment of colorectal cancer. Am J Cancer 2004; 3 (3): 187-94
-
(2004)
Am J Cancer
, vol.3
, Issue.3
, pp. 187-194
-
-
Croom, K.F.1
Foster, R.H.2
-
26
-
-
0030856731
-
Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders
-
Oct 15;
-
Presta LG, Chen H, O'Connor SJ, et al. Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders. Cancer Res 1997 Oct 15; 57 (20): 4593-9
-
(1997)
Cancer Res
, vol.57
, Issue.20
, pp. 4593-4599
-
-
Presta, L.G.1
Chen, H.2
O'Connor, S.J.3
-
27
-
-
20044375603
-
Biological activity of bevacizumab, a humanized anti-VEGF antibody in vitro
-
Wang Y, Fei D, Vanderlaan M, et al. Biological activity of bevacizumab, a humanized anti-VEGF antibody in vitro. Angiogenesis 2004; 7 (4): 335-45
-
(2004)
Angiogenesis
, vol.7
, Issue.4
, pp. 335-345
-
-
Wang, Y.1
Fei, D.2
Vanderlaan, M.3
-
28
-
-
0027197245
-
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
-
Apr 29;
-
Kim KJ, Li B, Winer J, et al. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 1993 Apr 29; 362 (6423): 841-4
-
(1993)
Nature
, vol.362
, Issue.6423
, pp. 841-844
-
-
Kim, K.J.1
Li, B.2
Winer, J.3
-
29
-
-
0035253739
-
Phase I safety and pharmacokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer
-
Gordon MS, Margolin K, Talpaz M, et al. Phase I safety and pharmacokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer. J Clin Oncol 2001; 19 (3): 843-50
-
(2001)
J Clin Oncol
, vol.19
, Issue.3
, pp. 843-850
-
-
Gordon, M.S.1
Margolin, K.2
Talpaz, M.3
-
30
-
-
0035253586
-
Phase 1b trial of intravenous recombinant humanized monoclonal antibody to vascular endothelial growth factor in combination with chemotherapy in patients with advanced cancer: Pharmacologic and long-term safety data
-
Margolin K, Gordon MS, Holmgren E, et al. Phase 1b trial of intravenous recombinant humanized monoclonal antibody to vascular endothelial growth factor in combination with chemotherapy in patients with advanced cancer: pharmacologic and long-term safety data. J Clin Oncol 2001; 19 (3): 851-6
-
(2001)
J Clin Oncol
, vol.19
, Issue.3
, pp. 851-856
-
-
Margolin, K.1
Gordon, M.S.2
Holmgren, E.3
-
31
-
-
0010775027
-
Pharmacokinetics (PK) of bevacizumab (BV) in colorectal cancer (CRC) [abstract no. PI-98]
-
Feb;
-
Gaudrealt J, Lieberman G, Kabbinavar F, et al. Pharmacokinetics (PK) of bevacizumab (BV) in colorectal cancer (CRC) [abstract no. PI-98]. Clin Pharmacol Ther 2001 Feb; 69 (2): P25
-
(2001)
Clin Pharmacol Ther
, vol.69
, Issue.2
-
-
Gaudrealt, J.1
Lieberman, G.2
Kabbinavar, F.3
-
32
-
-
40949136246
-
-
discussion [online, Available from URL:, Accessed 2007 Nov 30
-
European Medicines Agency. Avastin European Public Assessment Report: scientific discussion [online]. Available from URL: http://www.emea.europa.eu/ humandocs/PDFs/EPAR/avastin/17199204en6.pdf [Accessed 2007 Nov 30]
-
Avastin European Public Assessment Report: Scientific
-
-
-
34
-
-
35648938219
-
Randomized phase II study of erlotinib combined with bevacizumab compared with bevacizumab alone in metastatic renal cell cancer
-
Oct 10;
-
Bukowski RM, Kabbinavar FF, Figlin RA, et al. Randomized phase II study of erlotinib combined with bevacizumab compared with bevacizumab alone in metastatic renal cell cancer. J Clin Oncol 2007 Oct 10; 25 (29): 4536-41
-
(2007)
J Clin Oncol
, vol.25
, Issue.29
, pp. 4536-4541
-
-
Bukowski, R.M.1
Kabbinavar, F.F.2
Figlin, R.A.3
-
35
-
-
0042343801
-
A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
-
Jul 31;
-
Yang JC, Haworth L, Sherry RM, et al. A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer. N Engl J Med 2003 Jul 31; 349 (5): 427-34
-
(2003)
N Engl J Med
, vol.349
, Issue.5
, pp. 427-434
-
-
Yang, J.C.1
Haworth, L.2
Sherry, R.M.3
-
36
-
-
30944452354
-
Treatment of metastatic renal cell carcinoma with a combination of bevacizumab and erlotinib
-
Nov 1;
-
Hainsworth JD, Sosman JA, Spigel DR, et al. Treatment of metastatic renal cell carcinoma with a combination of bevacizumab and erlotinib. J Clin Oncol 2005 Nov 1; 23 (31): 7889-96
-
(2005)
J Clin Oncol
, vol.23
, Issue.31
, pp. 7889-7896
-
-
Hainsworth, J.D.1
Sosman, J.A.2
Spigel, D.R.3
-
37
-
-
37349080670
-
Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: A randomised, double-blind phase III trial
-
Dec 22;
-
Escudier B, Pluzanska A, Koralewski P, et al. Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial. Lancet 2007 Dec 22; 370 (9605): 2103-11
-
(2007)
Lancet
, vol.370
, Issue.9605
, pp. 2103-2111
-
-
Escudier, B.1
Pluzanska, A.2
Koralewski, P.3
-
38
-
-
1942470411
-
Cancer and Leukemia Group B 90206: A randomized phase III trial of interferon-alpha or interferon-alpha plus anti-vascular endothelial growth factor antibody (bevacizumab) in metastatic renal cell carcinoma
-
Apr 15;
-
Rini BI, Halabi S, Taylor J, et al. Cancer and Leukemia Group B 90206: a randomized phase III trial of interferon-alpha or interferon-alpha plus anti-vascular endothelial growth factor antibody (bevacizumab) in metastatic renal cell carcinoma. Clin Cancer Res 2004 Apr 15; 10 (8): 2584-6
-
(2004)
Clin Cancer Res
, vol.10
, Issue.8
, pp. 2584-2586
-
-
Rini, B.I.1
Halabi, S.2
Taylor, J.3
-
39
-
-
40949131919
-
-
Phase III randomized study of interferon alfa-2b with or without bevacizumab in patients with advanced renal cell carcinoma. Identifier: NCT00072046 [online]. Available from URL: http://clinicaltrials.gov/ct/show/ NCT00072046 [Accessed 2008 Feb 27]
-
Phase III randomized study of interferon alfa-2b with or without bevacizumab in patients with advanced renal cell carcinoma. Identifier: NCT00072046 [online]. Available from URL: http://clinicaltrials.gov/ct/show/ NCT00072046 [Accessed 2008 Feb 27]
-
-
-
-
40
-
-
40949118629
-
-
Escudier B, Koralewski P, Pluzanska A, et al. A randomized, controlled, double-blind phase III study (AVOREN) of bevacizumab/interferon-alpha-2a vs placebo/interferon-alpha-2a as first-line therapy in metastatic renal cell carcinoma [abstract no. 3]. J Clin Oncol 2007 Jun 20; 25 (18S Pt I): 2s-5. Plus oral presentation at the 2007 American Society of Clinical Oncology Annual Meeting; 2007 Jun 1
-
Escudier B, Koralewski P, Pluzanska A, et al. A randomized, controlled, double-blind phase III study (AVOREN) of bevacizumab/interferon-alpha-2a vs placebo/interferon-alpha-2a as first-line therapy in metastatic renal cell carcinoma [abstract no. 3]. J Clin Oncol 2007 Jun 20; 25 (18S Pt I): 2s-5. Plus oral presentation at the 2007 American Society of Clinical Oncology Annual Meeting; 2007 Jun 1
-
-
-
-
41
-
-
40949157663
-
-
Bracarda S, Koralewski P, Pluzanska A, et al. Bevacizumab/interferon- alpha2a provides a progression-free survival benefit in all prespecified patient sub-groups as first-line treatment of metastatic renal cell carcinoma (AVOREN) [abstract no. 4008]. EJC Supplements 2007 Sep; 5 (4): 281-2. Plus poster presented at the 2007 European Cancer Conference; 2007 Sep 23-27; Barcelona
-
Bracarda S, Koralewski P, Pluzanska A, et al. Bevacizumab/interferon- alpha2a provides a progression-free survival benefit in all prespecified patient sub-groups as first-line treatment of metastatic renal cell carcinoma (AVOREN) [abstract no. 4008]. EJC Supplements 2007 Sep; 5 (4): 281-2. Plus poster presented at the 2007 European Cancer Conference; 2007 Sep 23-27; Barcelona
-
-
-
-
42
-
-
40949134319
-
-
Melichar B, Koralewski P, Pluzanska A, et al. First-line bevacizumab improves progression-free survival with lower doses of interferon-alpha-2a in the treatment of patients with metastatic renal cell carcinoma (AVOREN) [abstract no. 4518]. EJC Supplements 2007 Sep; 5 (4): 304. Plus poster presented at the 2007 European Cancer Conference; 2007 Sep 23-27; Barcelona
-
Melichar B, Koralewski P, Pluzanska A, et al. First-line bevacizumab improves progression-free survival with lower doses of interferon-alpha-2a in the treatment of patients with metastatic renal cell carcinoma (AVOREN) [abstract no. 4518]. EJC Supplements 2007 Sep; 5 (4): 304. Plus poster presented at the 2007 European Cancer Conference; 2007 Sep 23-27; Barcelona
-
-
-
-
43
-
-
40949130113
-
-
Rini BI, Halabi S, Rosenberg JE, et al. CALGB 90206: a phase III trial of bevacizumab plus interferon-alpha versus interferon-alpha monotherapy in metastatic renal cell carcinoma [abstract no. 350]. Plus oral and poster presentations at the 2008 Genitourinary Cancers Symposium; 2008 Feb 14-16; San Francisco (CA) [online]. Available from URL: http://www.asco.org [Accessed 2008 Feb 27]
-
Rini BI, Halabi S, Rosenberg JE, et al. CALGB 90206: a phase III trial of bevacizumab plus interferon-alpha versus interferon-alpha monotherapy in metastatic renal cell carcinoma [abstract no. 350]. Plus oral and poster presentations at the 2008 Genitourinary Cancers Symposium; 2008 Feb 14-16; San Francisco (CA) [online]. Available from URL: http://www.asco.org [Accessed 2008 Feb 27]
-
-
-
-
46
-
-
34247849335
-
Target practice: Lessons from phase III trials with bevacizumab and vatalanib in the treatment of advanced colorectal cancer
-
Los M, Roodhart JML, Voest EE. Target practice: lessons from phase III trials with bevacizumab and vatalanib in the treatment of advanced colorectal cancer. Oncologist 2007; 12: 443-50
-
(2007)
Oncologist
, vol.12
, pp. 443-450
-
-
Los, M.1
Roodhart, J.M.L.2
Voest, E.E.3
-
47
-
-
40949100537
-
-
Feldman DR, Kondagunta GV, Ronnen EA, et al. Phase I trial of bevacizumab plus sunitinib in patients (pts) with metastatic renal cell carcinoma (mRCC). J Clin Oncol, 2007 ASCO Annual Meeting Proceedings 2007 Jun 20; 25 (18S Pt 1): 5099
-
Feldman DR, Kondagunta GV, Ronnen EA, et al. Phase I trial of bevacizumab plus sunitinib in patients (pts) with metastatic renal cell carcinoma (mRCC). J Clin Oncol, 2007 ASCO Annual Meeting Proceedings 2007 Jun 20; 25 (18S Pt 1): 5099
-
-
-
-
48
-
-
40949154440
-
-
Sosman JA, Flaherty K, Atkins MB. A phase I/II trial of sorafenib (S) with bevacizumab (B) in metastatic renal cell cancer (mRCC) patients (pts). J Clin Oncol, 2006 ASCO Annual Meeting Proceedings 2006 Jun 20; 24 (18S Pt 1): 3031
-
Sosman JA, Flaherty K, Atkins MB. A phase I/II trial of sorafenib (S) with bevacizumab (B) in metastatic renal cell cancer (mRCC) patients (pts). J Clin Oncol, 2006 ASCO Annual Meeting Proceedings 2006 Jun 20; 24 (18S Pt 1): 3031
-
-
-
|