Development and validation of a liquid chromatography-tandem mass spectrometric assay for pitavastatin and its lactone in human plasma and urine

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 865, Issue 1-2, 2008, Pages 127-132

  Tian, Lei ^a   Huang, Yiling ^a   Jia, Youhong ^a   Hua, Lu ^a   Li, Yishi ^a  

^a FUWAI HOSPITAL   (China)

Author keywords

Liquid chromatography; Pitavastatin; Pitavastatin lactone; Tandem mass spectrometry

Indexed keywords

LACTONE; PITAVASTATIN; PITAVASTATIN LACTONE; TANDEM MASS SPECTROMETRY;

BODY FLUIDS; ELECTROSPRAY IONIZATION; EXTRACTION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PLASMA (HUMAN);

DRUG PRODUCTS;

ACETIC ACID; METHANOL; PITAVASTATIN; PITAVASTATIN LACTONE; UNCLASSIFIED DRUG; WATER;

ACCURACY; ARTICLE; BLOOD LEVEL; CALIBRATION; CONCENTRATION (PARAMETERS); DRUG DETERMINATION; DRUG MONITORING; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MULTIPLE REACTION MONITORING; PRIORITY JOURNAL; RACEMIZATION; SENSITIVITY AND SPECIFICITY; STANDARD; TANDEM MASS SPECTROMETRY; URINE LEVEL;

CHROMATOGRAPHY, LIQUID; HUMANS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; LACTONES; QUINOLINES; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 40949128200     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2008.02.017     Document Type: Article

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