Expression and clinical significance of epidermal growth factor receptor and type 1 insulin-like growth factor receptor in nasopharyngeal carcinoma

Annals of Otology, Rhinology and Laryngology

Volumn 117, Issue 3, 2008, Pages 192-200

  Yuan, Yulin ^a   Zhou, Xuhong ^b   Song, Jian ^a,c   Qiu, Xiaoping ^c   Li, Jun ^b   Ye, Linfeng ^b   Meng, Xiaoping ^a   Xia, Dong ^a  

^a WUHAN UNIVERSITY   (China)

^b ZHONGNAN HOSPITAL OF WUHAN UNIVERSITY   (China)

^c WUHAN UNIVERSITY   (China)

Author keywords

Epidermal growth factor receptor; Immunohistochemistry; Nasopharyngeal carcinoma; Real time quantitative polymerase chain reaction; Type 1 insulin like growth factor receptor; Western blot technique

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; SOMATOMEDIN C RECEPTOR;

APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER STAGING; CLINICAL FEATURE; CONTROLLED STUDY; CORRELATION COEFFICIENT; HUMAN; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; NASOPHARYNX CARCINOMA; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURVIVAL; WESTERN BLOTTING;

EID: 40949127033     PISSN: 00034894     EISSN: None     Source Type: Journal    
DOI: 10.1177/000348940811700306     Document Type: Article

References (21)

1. Chan J, Plich BZ, Kuo TT. Nasopharyngeal carcinoma. In: Barnes L, Eveson JW, Reichart P, Sidransky D, eds. WHO classification of tumors - pathology and genetics: head and neck tumors. Lyon, France: IARC Press, 2005:85-97.
2. Ayan I, Kaytan E, Ayan N. Childhood nasopharyngeal carcinoma: from biology to treatment. Lancet Oncol 2003;4:13-21.
3. Cammoun M, Hoerner V, Mourali N. Tumors of the nasopharynx in Tunisia. An anatomic and clinical study based on 143 cases. Cancer 1974;33:184-92.
4. Rodriguez-Galindo C, Wofford M, Castleberry RP, et al. Preradiation chemotherapy with methotrexate, cisplatin, 5-fluorouracil, and leucovorin for pediatric nasopharyngeal carcinoma. Cancer 2005;103:850-7.
5. Dannenberg AJ, Lippman SM, Mann JR, Subbaramaiah K, DuBois RN. Cyclooxygenase-2 and epidermal growth factor receptor: pharmacologic targets for chemoprevention. J Clin Oncol 2005;23:254-66.
6. Salomon DS, Brandt R, Ciardiello F, Normanno N. Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 1995;19:183-232.
7. Davies DE, Chamberlin SG. Targeting the epidermal growth factor receptor for therapy of carcinomas. Biochem Pharmacol 1996;51:1101-10.
8. Rusch V, Mendelsohn J, Dmitrovsky E. The epidermal growth factor receptor and its ligands as therapeutic targets in human tumors. Cytokine Growth Factor Rev 1996;7:133-41.
9. Grandis JR, Chakraborty A, Zeng Q, Melhem MF, Tweardy DJ. Downmodulation of TGF-alpha protein expression with antisense oligonucleotides inhibits proliferation of head and neck squamous carcinoma but not normal mucosal epithelial cells. J Cell Biochem 1998;69:55-62.
10. Baserga R. Oncogenes and the strategy of growth factors. Cell 1994;79:927-30.
11. Wang Y, Sun Y. Insulin-like growth factor receptor-1 as an anti-cancer target: blocking transformation and inducing apoptosis. Curr Cancer Drug Targets 2002;2:191-207.
12. Wang Z, Ruan YB, Guan Y, Liu SH. Expression of IGF-II in early experimental hepatocellular carcinomas and its significance in early diagnosis. World J Gastroenterol 2003;9:267-70.
13. Lu Y, Zi X, Pollak M. Molecular mechanisms underlying IGF-I-induced attenuation of the growth-inhibitory activity of trastuzumab (Herceptin) on SKBR3 breast cancer cells. Int J Cancer 2004;108:334-41.
14. Kuribayashi A, Kataoka K, Kurabayashi T, Miura M. Evidence that basal activity, but not transactivation, of the epidermal growth factor receptor tyrosine kinase is required for insulin-like growth factor I-induced activation of extracellular signal-regulated kinase in oral carcinoma cells. Endocrinology 2004;145:4976-84.
15. Zhang Q, Thomas SM, Lui VW, et al. Phosphorylation of TNF-alpha converting enzyme by gastrin-releasing peptide induces amphiregulin release and EGF receptor activation. Proc Natl Acad Sci U S A 2006;103:6901-6.
16. Ahmad T, Farnie G, Bundred NJ, Anderson NG. The mitogenic action of insulin-like growth factor I in normal human mammary epithelial cells requires the epidermal growth factor receptor tyrosine kinase. J Biol Chem 2004;279:1713-9.
17. Knowlden JM, Hutcheson IR, Barrow D, Gee JM, Nicholson RI. Insulin-like growth factor-1 receptor signaling in tamoxifen-resistant breast cancer: a supporting role to the epidermal growth factor receptor. Endocrinology 2005;146:4609-18.
18. Soo R, Putti T, Tao Q, et al. Overexpression of cyclooxygenase-2 in nasopharyngeal carcinoma and association with epidermal growth factor receptor expression. Arch Otolaryngol Head Neck Surg 2005;131:147-52.
19. Lu JC, Wei BQ, Chen WZ, et al. Staging of nasopharyngeal carcinoma investigated by magnetic resonance imaging. Radiother Oncol 2006;79:21-6.
20. Lee AW, Au JS, Teo PM, et al. Staging of nasopharyngeal carcinoma: suggestions for improving the current UICC/AJCC staging system. Clin Oncol (R Coll Radiol) 2004;16:269-76.
21. Vokes EE, Liebowitz DN, Weichselbaum RR. Nasopharyngeal carcinoma. Lancet 1997;350:1087-91.