Early- and late-onset ventilator-associated pneumonia acquired in the intensive care unit: comparison of risk factors

Journal of Critical Care

Volumn 23, Issue 1, 2008, Pages 27-33

  Giard, Marine ^a,b   Lepape, Alain ^c   Allaouchiche, Bernard ^b   Guerin, Claude ^d   Lehot, Jean Jacques ^e   Robert, Marc Olivier ^d   Fournier, Gérard ^c   Jacques, Didier ^c   Chassard, Dominique ^f   Gueugniaud, Pierre Yves ^c   Artru, François ^g   Petit, Paul ^b   Robert, Dominique ^b   Mohammedi, Ismaël ^b   Girard, Raphaëlle ^c   Cêtre, Jean Charles ^d   Nicolle, Marie Christine ^d   Grando, Jacqueline ^e   Fabry, Jacques ^a,b   Vanhems, Philippe ^a,b  

^a UNIVERSITÉ LYON 1   (France)

^b EDOUARD HERRIOT HOSPITAL   (France)

^c CENTRE HOSPITALIER LYON SUD   (France)

^d CROIX ROUSSE HOSPITAL   (France)

^e LOUIS PRADEL HOSPITAL   (France)

^f HÔTEL DIEU   (France)

^g Pierre Wertheimer Hospital   (France)

Author keywords

Early and late onset; Epidemiology; Intensive care units; Nosocomial infection; Risk factors; Ventilator associated pneumonia

Indexed keywords

ADULT; AGED; ARTICLE; CENTRAL VENOUS CATHETER; COMPARATIVE STUDY; CONFIDENCE INTERVAL; CONTROLLED STUDY; DEVICE; FEMALE; HAZARD RATIO; HEALTH PROGRAM; HEALTH SURVEY; HOSPITAL ADMISSION; HOSPITAL INFECTION; HUMAN; INCIDENCE; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; RISK ASSESSMENT; RISK FACTOR; TIME SERIES ANALYSIS; VENTILATOR ASSOCIATED PNEUMONIA;

ADULT; AGED; ANTI-BACTERIAL AGENTS; CHI-SQUARE DISTRIBUTION; FEMALE; FRANCE; HUMANS; INCIDENCE; INTENSIVE CARE UNITS; MALE; MIDDLE AGED; PNEUMONIA, VENTILATOR-ASSOCIATED; POPULATION SURVEILLANCE; PROSPECTIVE STUDIES; RISK FACTORS; STATISTICS, NONPARAMETRIC;

EID: 40949118958     PISSN: 08839441     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcrc.2007.08.005     Document Type: Article

References (23)

1. Vincent J.L. Ventilator-associated pneumonia. J Hosp Infect 57 (2004) 272-280
2. Mehta R.M., and Niederman M.S. Nosocomial pneumonia. Curr Opin Infect Dis 15 (2002) 387-394
3. Chevret S., Hemmer M., Carlet J., et al. Incidence and risk factors of pneumonia acquired in intensive care units. Results from a multicenter prospective study on 996 patients. European Cooperative Group on Nosocomial Pneumonia. Intensive Care Med 19 (1993) 256-264
4. Cook D.J., Walter S.D., Cook R.J., et al. Incidence of and risk factors for ventilator-associated pneumonia in critically ill patients. Ann Intern Med 129 (1998) 433-440
5. Fagon J.Y., Chastre J., Vuagnat A., et al. Nosocomial pneumonia and mortality among patients in intensive care units. JAMA 275 (1996) 866-869
6. Mandelli M., Mosconi P., Langer M., et al. Is pneumonia developing in patients in intensive care always a typical "nosocomial" infection?. Lancet 2 (1986) 1094-1095
7. American Thoracic Society. Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med 171 (2005) 388-416
8. Moine P., Timsit J.F., De Lassence A., et al. Mortality associated with late-onset pneumonia in the intensive care unit: results of a multi-center cohort study. Intensive Care Med 28 (2002) 154-163
9. Akca O., Koltka K., Uzel S., et al. Risk factors for early-onset, ventilator-associated pneumonia in critical care patients: selected multiresistant versus nonresistant bacteria. Anesthesiology 93 (2000) 638-645
10. Ibrahim E.H., Ward S., Sherman G., et al. A comparative analysis of patients with early-onset vs late-onset nosocomial pneumonia in the ICU setting. Chest 117 (2000) 1434-1442
11. Kollef M.H., Silver P., Murphy D.M., et al. The effect of late-onset ventilator-associated pneumonia in determining patient mortality. Chest 108 (1995) 1655-1662
12. Nseir S., Di Pompeo C., Pronnier P., et al. Early and late nosocomial broncho-pulmonary diseases in intensive care. Comparative study of risk factors and of causing bacteria. Presse Med 32 (2003) 1111-1115
13. Heyland D.K., Cook D.J., Griffith L., et al. The attributable morbidity and mortality of ventilator-associated pneumonia in the critically ill patient. The Canadian Critical Trials Group. Am J Respir Crit Care Med 159 (1999) 1249-1256
14. Trouillet L., Chastre J., Vuagnat A., et al. Ventilator-associated pneumonia caused by potentially drug-resistant bacteria. Am J Respir Crit Care Med 157 (1998) 531-539
15. Chastre J., and Fagon J.Y. Ventilator-associated pneumonia. Am J Respir Crit Care Med 165 (2002) 867-903
16. Bert F., and Lambert-Zechovsky N. Bactéries isolées de prélèvements bronchopulmonaires protégés: variation en fonction de la durée de séjour préalable en réanimation. Pathol Biol 46 (1998) 380-384
17. Vanhems P., Lepape A., Savey A., et al. Nosocomial pulmonary infection by antimicrobial-resistant bacteria of patients hospitalized in intensive care units: risk factors and survival. J Hosp Infect 45 (2000) 98-106
18. Le Gall J.R., Lemeshow S., and Saulnier F. A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study. JAMA 270 (1993) 2957-2963
19. Savey A., Lepape A., Caillat-Vallet E., et al. Protocole de surveillance Réa Sud-Est (2004), Centre de Coordination de la Lutte contre les Infections Nosocomiales du Sud-Est, Lyon 14-15
20. Couty E., and Ménard J. 100 recommandations pour la surveillance et la prévention des infections nosocomiales. 2nd ed. (1999), Comité technique national des infections nosocomiales, Ministére de l'emploi et de la solidarité, Secrétariat d'Etat à la santé et à l'action sociale, Paris 12-15
21. In: Comité de l'antibiogramme, Société Française de Microbiologie, and Société Française de Microbiologie (Eds). Créteil (2005) 15-25
22. Rello J., Ausina V., Ricart M., et al. Impact of previous antimicrobial therapy on the etiology and outcome of ventilator-associated pneumonia. Chest 104 (1993) 1230-1235
23. Defouilloy C., Gérard A., Berche P., et al. Evaluation d'un stratégie thérapeutique utilisant l'association amoxicilline-acide clavulanique par voir veineuse avec relais oral dans les pneumopathies précoces du patient sous ventilation artificielle. Méd Mal Infect 31 (2001) 7-13