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Volumn 32, Issue 3, 2008, Pages 407-412

Genetic variation of the adenylyl cyclase 3 (AC3) locus and its influence on type 2 diabetes and obesity susceptibility in Swedish men

Author keywords

Adenylyl cyclase 3; Association; Single nucleotide polymorphism; Type 2 diabetes

Indexed keywords

ADENYLYL CYCLASE 3 GENE; ADULT; ARTICLE; BODY MASS; CONTROLLED STUDY; DISEASE PREDISPOSITION; GENE; GENE LOCUS; GENETIC VARIABILITY; GENOTYPE; GLUCOSE TOLERANCE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 40949106075     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/sj.ijo.0803742     Document Type: Article
Times cited : (50)

References (22)
  • 1
    • 33748997922 scopus 로고    scopus 로고
    • Type 2 diabetes: A cocktail of genetic discovery
    • Freeman H, Cox RD. Type 2 diabetes: a cocktail of genetic discovery. Hum Mol Genet 2006; 15 (Suppl 2): R202-R209.
    • (2006) Hum Mol Genet , vol.15 , Issue.SUPPL. 2
    • Freeman, H.1    Cox, R.D.2
  • 2
    • 59849128464 scopus 로고    scopus 로고
    • Genetics of obesity in human
    • Farooqi IS, O'rahilly S. Genetics of obesity in human. Endocr Rev 2006; 361: 1095-1105.
    • (2006) Endocr Rev , vol.361 , pp. 1095-1105
    • Farooqi, I.S.1    O'rahilly, S.2
  • 3
    • 0035040818 scopus 로고    scopus 로고
    • Regulation and role of adenylyl cyclase isoforms
    • Hanoune J, Defer N. Regulation and role of adenylyl cyclase isoforms. Annu Rev Pharmacol Toxicol 2001; 41: 145-174.
    • (2001) Annu Rev Pharmacol Toxicol , vol.41 , pp. 145-174
    • Hanoune, J.1    Defer, N.2
  • 5
    • 0027246174 scopus 로고
    • Both somatostatin and insulin responses to glucose are impaired in the perfused pancreas of the spontaneously noninsulin-dependent diabetic GK (Goto-Kakizaki) rats
    • Abdel-Halim SM, Guenifi A, Efendic S, Ostenson CG. Both somatostatin and insulin responses to glucose are impaired in the perfused pancreas of the spontaneously noninsulin-dependent diabetic GK (Goto-Kakizaki) rats. Acta Physiol Scand 1993; 148: 219-226.
    • (1993) Acta Physiol Scand , vol.148 , pp. 219-226
    • Abdel-Halim, S.M.1    Guenifi, A.2    Efendic, S.3    Ostenson, C.G.4
  • 6
    • 0028144530 scopus 로고
    • Impact of diabetic inheritance on glucose tolerance and insulin secretion in spontaneously diabetic GK-Wistar rats
    • Abdel-Halim SM, Guenifi A, Luthman H, Grill V, Efendic S, Ostenson CG. Impact of diabetic inheritance on glucose tolerance and insulin secretion in spontaneously diabetic GK-Wistar rats. Diabetes 1994; 43: 281-288.
    • (1994) Diabetes , vol.43 , pp. 281-288
    • Abdel-Halim, S.M.1    Guenifi, A.2    Luthman, H.3    Grill, V.4    Efendic, S.5    Ostenson, C.G.6
  • 7
    • 0028839232 scopus 로고
    • A defective stimulus-secretion coupling rather than glucotoxicity mediates the impaired insulin secretion in the mildly diabetic F1 hybrids of GK-Wistar rats
    • Abdel-Halim SM, Ostenson CG, Andersson A, Jansson L, Efendic S. A defective stimulus-secretion coupling rather than glucotoxicity mediates the impaired insulin secretion in the mildly diabetic F1 hybrids of GK-Wistar rats. Diabetes 1995; 44: 1280-1284.
    • (1995) Diabetes , vol.44 , pp. 1280-1284
    • Abdel-Halim, S.M.1    Ostenson, C.G.2    Andersson, A.3    Jansson, L.4    Efendic, S.5
  • 8
    • 0031914387 scopus 로고    scopus 로고
    • Mutations in the promoter of adenylyl cyclase (AC)-III gene, overexpression of AC-III mRNA, and enhanced cAMP generation in islets from the spontaneously diabetic GK rat model of type 2 diabetes
    • Abdel-Halim SM, Guenifi A, He B, Yang B, Mustafa M, Hojeberg B et al. Mutations in the promoter of adenylyl cyclase (AC)-III gene, overexpression of AC-III mRNA, and enhanced cAMP generation in islets from the spontaneously diabetic GK rat model of type 2 diabetes. Diabetes 1998; 47: 498-504.
    • (1998) Diabetes , vol.47 , pp. 498-504
    • Abdel-Halim, S.M.1    Guenifi, A.2    He, B.3    Yang, B.4    Mustafa, M.5    Hojeberg, B.6
  • 9
    • 0029900592 scopus 로고    scopus 로고
    • Impaired coupling of glucose signal to the exocytotic machinery in diabetic GK rats: A defect ameliorated by cAMP
    • Abdel-Halim SM, Guenifi A, Khan A, Larsson O, Berggren PO, Ostenson CG et al. Impaired coupling of glucose signal to the exocytotic machinery in diabetic GK rats: a defect ameliorated by cAMP. Diabetes 1996; 45: 934-940.
    • (1996) Diabetes , vol.45 , pp. 934-940
    • Abdel-Halim, S.M.1    Guenifi, A.2    Khan, A.3    Larsson, O.4    Berggren, P.O.5    Ostenson, C.G.6
  • 10
    • 0028222256 scopus 로고
    • Liver β-adrenergic receptors, G proteins, and adenylyl cyclase activity in obesity-diabetes syndromes
    • Begin-Heick N. Liver β-adrenergic receptors, G proteins, and adenylyl cyclase activity in obesity-diabetes syndromes. Am J Physiol 1994; 94: C1664-C1672.
    • (1994) Am J Physiol , vol.94
    • Begin-Heick, N.1
  • 12
    • 0032932340 scopus 로고    scopus 로고
    • Family history of diabetes in middle-aged Swedish men is a gender unrelated factor, which is associated with insulinopenia in newly diagnosed diabetic subjects
    • Grill V, Persson G, Carlsson S, Norman A, Alvarsson M, Ostensson CG et al. Family history of diabetes in middle-aged Swedish men is a gender unrelated factor, which is associated with insulinopenia in newly diagnosed diabetic subjects. Diabetologia 1999; 42: 15-23.
    • (1999) Diabetologia , vol.42 , pp. 15-23
    • Grill, V.1    Persson, G.2    Carlsson, S.3    Norman, A.4    Alvarsson, M.5    Ostensson, C.G.6
  • 13
    • 0042167252 scopus 로고    scopus 로고
    • Work stress and low sense of coherence is associated with type 2 diabetes in middle-aged Swedish women
    • Agardh EE, Ahlbom A, Andersson T, Efendic S, Grill V, Hallqvist J et al. Work stress and low sense of coherence is associated with type 2 diabetes in middle-aged Swedish women. Diabetes care 2003; 5: 719-724.
    • (2003) Diabetes care , vol.5 , pp. 719-724
    • Agardh, E.E.1    Ahlbom, A.2    Andersson, T.3    Efendic, S.4    Grill, V.5    Hallqvist, J.6
  • 14
    • 0031851293 scopus 로고    scopus 로고
    • Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation
    • Alberti KG, Zimmet P. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabetic Med 1998; 15: 539.
    • (1998) Diabetic Med , vol.15 , pp. 539
    • Alberti, K.G.1    Zimmet, P.2
  • 15
    • 0028222256 scopus 로고
    • Liver β-adrenergic receptors, G proteins, and adenylyl cyclase activity in obesity-diabetes syndromes
    • Begin-Heick N. Liver β-adrenergic receptors, G proteins, and adenylyl cyclase activity in obesity-diabetes syndromes. Am J Physiol 1994; 94: C1664-C1672.
    • (1994) Am J Physiol , vol.94
    • Begin-Heick, N.1
  • 16
    • 0027164996 scopus 로고
    • Functional expression of the rat glucagon-like peptide-I receptor, evidence for coupling to both adenylyl cyclase and phospholipase-C
    • Wheeler MB, Lu M, Dillon JS, Leng XH, Chen C, Boyd III AE. Functional expression of the rat glucagon-like peptide-I receptor, evidence for coupling to both adenylyl cyclase and phospholipase-C. Endocrinology 1993; 133: 57-62.
    • (1993) Endocrinology , vol.133 , pp. 57-62
    • Wheeler, M.B.1    Lu, M.2    Dillon, J.S.3    Leng, X.H.4    Chen, C.5    Boyd III, A.E.6
  • 17
    • 17144374043 scopus 로고    scopus 로고
    • The recombinant rat glucagon-like peptide-1 receptor, expressed in an alpha-cell line, is coupled to adenylyl cyclase activation and intracellular calcium release
    • Dillon JS, Lu M, Bowen S, Homan LL. The recombinant rat glucagon-like peptide-1 receptor, expressed in an alpha-cell line, is coupled to adenylyl cyclase activation and intracellular calcium release. Exp Clin Endocrinol Diabetes 2005; 113: 182-189.
    • (2005) Exp Clin Endocrinol Diabetes , vol.113 , pp. 182-189
    • Dillon, J.S.1    Lu, M.2    Bowen, S.3    Homan, L.L.4
  • 18
    • 0037437729 scopus 로고    scopus 로고
    • Cooperative enhancement of insulinotropic action of GLP-1 by acetylcholine uncovers paradoxical inhibitory effect of beta cell muscarinic receptor activation on adenylate cyclase activity
    • Miguel JC, Abdel-Wahab YH, Green BD, Mathias PC, Flatt PR. Cooperative enhancement of insulinotropic action of GLP-1 by acetylcholine uncovers paradoxical inhibitory effect of beta cell muscarinic receptor activation on adenylate cyclase activity. Biochem Pharmacol 2003; 65: 283-292.
    • (2003) Biochem Pharmacol , vol.65 , pp. 283-292
    • Miguel, J.C.1    Abdel-Wahab, Y.H.2    Green, B.D.3    Mathias, P.C.4    Flatt, P.R.5
  • 19
    • 33750314863 scopus 로고    scopus 로고
    • Modulation of cyclic nucleotides and cyclic nucleotide phosphodiesterases in pancreatic islet β-cells and intestinal L-cells as targets for treating diabetes mellitus
    • Furman B, Pyne N. Modulation of cyclic nucleotides and cyclic nucleotide phosphodiesterases in pancreatic islet β-cells and intestinal L-cells as targets for treating diabetes mellitus. Curr Opin Invest Drugs 2006; 7: 898-905.
    • (2006) Curr Opin Invest Drugs , vol.7 , pp. 898-905
    • Furman, B.1    Pyne, N.2
  • 20
    • 0037299115 scopus 로고    scopus 로고
    • Effects of the novel (pro3) GIP antagonist and exendin (9-39) amide on GIP- and GLP-1-induced cyclic AMP generation, insulin secretion and postprandial insulin release in obese diabetic (ob/ob) mice: Evidence that GIP is the major physiological incretin
    • Gault VA, O'Harte FP, Harriott P, Mooney MH, Green BD, Flatt PR. Effects of the novel (pro3) GIP antagonist and exendin (9-39) amide on GIP- and GLP-1-induced cyclic AMP generation, insulin secretion and postprandial insulin release in obese diabetic (ob/ob) mice: evidence that GIP is the major physiological incretin. Diabetologia 2003; 46: 222-230.
    • (2003) Diabetologia , vol.46 , pp. 222-230
    • Gault, V.A.1    O'Harte, F.P.2    Harriott, P.3    Mooney, M.H.4    Green, B.D.5    Flatt, P.R.6
  • 21
    • 0014803946 scopus 로고
    • Catecholamines and metabolism of human adipose tissue. 3. Comparison between the regulation of lipolysis in omental and subcutaneous adipose tissue
    • Efendic S. Catecholamines and metabolism of human adipose tissue. 3. Comparison between the regulation of lipolysis in omental and subcutaneous adipose tissue. Acta Med Scand 1970; 187: 477-483.
    • (1970) Acta Med Scand , vol.187 , pp. 477-483
    • Efendic, S.1
  • 22
    • 4544357340 scopus 로고    scopus 로고
    • Learning new tricks from old dogs: Beta-adrenergic receptors teach new lessons on firing up adipose tissue metabolism
    • Collins S, Cao W, Robidoux J. Learning new tricks from old dogs: beta-adrenergic receptors teach new lessons on firing up adipose tissue metabolism. Mol Endocrinol 2004; 18: 2123-2131.
    • (2004) Mol Endocrinol , vol.18 , pp. 2123-2131
    • Collins, S.1    Cao, W.2    Robidoux, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.