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Volumn 29, Issue 3, 2008, Pages 536-543

Jun D cooperates with p65 to activate the proximal κB site of the cyclin D1 promoter: Role of PI3K/PDK-1

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CYCLIN D1; DNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN C FOS; PROTEIN C JUN; PROTEIN P50; SMALL INTERFERING RNA; SYNAPTOTAGMIN I; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR JUND;

EID: 40949099918     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgm293     Document Type: Article
Times cited : (26)

References (47)
  • 1
    • 0032588186 scopus 로고    scopus 로고
    • NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1
    • Guttridge,D.C. et al. (1999) NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1. Mol. Cell Biol., 19, 5785-5799.
    • (1999) Mol. Cell Biol , vol.19 , pp. 5785-5799
    • Guttridge, D.C.1
  • 2
    • 0033520458 scopus 로고    scopus 로고
    • Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-kappaB-dependent pathway
    • Joyce,D. et al. (1999) Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-kappaB-dependent pathway. J. Biol. Chem., 274, 25245-25249.
    • (1999) J. Biol. Chem , vol.274 , pp. 25245-25249
    • Joyce, D.1
  • 3
    • 0036546501 scopus 로고    scopus 로고
    • NF-κB in cancer: From innocent bystander to major culprit
    • Karin,M. et al. (2002) NF-κB in cancer: From innocent bystander to major culprit. Nat. Rev. Cancer, 2, 301-310.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 301-310
    • Karin, M.1
  • 4
    • 0035797488 scopus 로고    scopus 로고
    • Murine embryonic fibroblasts lacking TC-PTP display delayed G1 phase through defective NF-kappaB activation
    • Ibarra-Sanchez,M.J. et al. (2001) Murine embryonic fibroblasts lacking TC-PTP display delayed G1 phase through defective NF-kappaB activation. Oncogene, 20, 4728-4739.
    • (2001) Oncogene , vol.20 , pp. 4728-4739
    • Ibarra-Sanchez, M.J.1
  • 5
    • 26844491712 scopus 로고    scopus 로고
    • Medroxyprogesterone acetate induces cell proliferation through up-regulation of cyclin D1 expression via phosphatidylinositol 3-kinase/Akt/nuclear factor-kappaB cascade in human breast cancer cells
    • Saitoh,M. et al. (2005) Medroxyprogesterone acetate induces cell proliferation through up-regulation of cyclin D1 expression via phosphatidylinositol 3-kinase/Akt/nuclear factor-kappaB cascade in human breast cancer cells. Endocrinology, 146, 4917-4925.
    • (2005) Endocrinology , vol.146 , pp. 4917-4925
    • Saitoh, M.1
  • 6
    • 0037675869 scopus 로고    scopus 로고
    • NF-kappa B-dependent induction of cyclin D1 by retinoblastoma protein (pRB) family proteins and tumor-derived pRB mutant
    • Takebayashi,T. et al. (2003) NF-kappa B-dependent induction of cyclin D1 by retinoblastoma protein (pRB) family proteins and tumor-derived pRB mutant. J. Biol. Chem., 278, 14897-14905.
    • (2003) J. Biol. Chem , vol.278 , pp. 14897-14905
    • Takebayashi, T.1
  • 7
    • 0024548862 scopus 로고
    • Regulation of liver growth: Protooncogenes and transforming growth factors
    • Fausto,N. et al. (1989) Regulation of liver growth: Protooncogenes and transforming growth factors. Lab. Invest., 60, 4-13.
    • (1989) Lab. Invest , vol.60 , pp. 4-13
    • Fausto, N.1
  • 8
    • 0030694249 scopus 로고    scopus 로고
    • Presence of distinct AP-1 dimers in normal and transformed rat hepatocytes under basal conditions and after epidermal growth factor stimulation
    • Nadori,F. et al. (1997) Presence of distinct AP-1 dimers in normal and transformed rat hepatocytes under basal conditions and after epidermal growth factor stimulation. Hepatology, 26, 1477-1483.
    • (1997) Hepatology , vol.26 , pp. 1477-1483
    • Nadori, F.1
  • 9
    • 0028970609 scopus 로고
    • Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions
    • Albanese,C. et al. (1995) Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions. J. Biol. Chem., 270, 23589-23597.
    • (1995) J. Biol. Chem , vol.270 , pp. 23589-23597
    • Albanese, C.1
  • 10
    • 0031865948 scopus 로고    scopus 로고
    • Fos family members induce cell cycle entry by activating cyclin D1
    • Brown,J.R. et al. (1998) Fos family members induce cell cycle entry by activating cyclin D1. Mol. Cell Biol., 18, 5609-5619.
    • (1998) Mol. Cell Biol , vol.18 , pp. 5609-5619
    • Brown, J.R.1
  • 11
    • 0033607541 scopus 로고    scopus 로고
    • Activation of the cyclin D1 gene by the E1A-associated protein p300 through AP-1 inhibits cellular apoptosis
    • Albanese,C. et al. (1999) Activation of the cyclin D1 gene by the E1A-associated protein p300 through AP-1 inhibits cellular apoptosis. J. Biol. Chem., 274, 34186-34195.
    • (1999) J. Biol. Chem , vol.274 , pp. 34186-34195
    • Albanese, C.1
  • 12
    • 0033521651 scopus 로고    scopus 로고
    • c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms
    • Wisdom,R. et al. (1999) c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms. EMBO J., 18, 188-197.
    • (1999) EMBO J , vol.18 , pp. 188-197
    • Wisdom, R.1
  • 13
    • 0027224017 scopus 로고
    • Cross-coupling of the NF-kappa 8 p65 and Fos/Jun transcription factors produces potentiated biological function
    • Stein,B. et al. (1993) Cross-coupling of the NF-kappa 8 p65 and Fos/Jun transcription factors produces potentiated biological function. EMBO J., 12, 3879-3891.
    • (1993) EMBO J , vol.12 , pp. 3879-3891
    • Stein, B.1
  • 14
    • 0033600851 scopus 로고    scopus 로고
    • ERK MAP kinase links cytokine signals to activation of latent HIV-1 infection by stimulating a cooperative interaction of AP-1 and NF-kappaB
    • Yang,X. et al. (1999) ERK MAP kinase links cytokine signals to activation of latent HIV-1 infection by stimulating a cooperative interaction of AP-1 and NF-kappaB. J. Biol. Chem., 274, 27981-27988.
    • (1999) J. Biol. Chem , vol.274 , pp. 27981-27988
    • Yang, X.1
  • 15
    • 0035939840 scopus 로고    scopus 로고
    • Functional cooperation between JunD and NF-kappaB in rat hepatocytes
    • Rahmani,M. et al. (2001) Functional cooperation between JunD and NF-kappaB in rat hepatocytes. Oncogene, 20, 5132-5142.
    • (2001) Oncogene , vol.20 , pp. 5132-5142
    • Rahmani, M.1
  • 16
    • 34249336416 scopus 로고    scopus 로고
    • Physical and functional cooperation between AP-1 and beta-catenin for the regulation of TCF-dependent genes
    • Toualbi,K. et al. (2007) Physical and functional cooperation between AP-1 and beta-catenin for the regulation of TCF-dependent genes. Oncogene, 26, 3492-3502.
    • (2007) Oncogene , vol.26 , pp. 3492-3502
    • Toualbi, K.1
  • 17
    • 0035971146 scopus 로고    scopus 로고
    • Potentiation of Smad transactivation by Jun proteins during a combined treatment with epidermal growth factor and transforming growth factor-beta in rat hepatocytes. Role of phosphatidylinositol 3-kinase-induced AP-1 activation
    • Peron,P. et al. (2001) Potentiation of Smad transactivation by Jun proteins during a combined treatment with epidermal growth factor and transforming growth factor-beta in rat hepatocytes. Role of phosphatidylinositol 3-kinase-induced AP-1 activation. J. Biol. Chem. 276, 10524-10531.
    • (2001) J. Biol. Chem , vol.276 , pp. 10524-10531
    • Peron, P.1
  • 18
    • 10644224272 scopus 로고    scopus 로고
    • Induction of the RelB NF-kappaB subunit by the cytomegalovirus IE1 protein is mediated via Jun kinase and c-Jun/ Fra-2 AP-1 complexes
    • Wang,X. et al. (2005) Induction of the RelB NF-kappaB subunit by the cytomegalovirus IE1 protein is mediated via Jun kinase and c-Jun/ Fra-2 AP-1 complexes. J. Virol., 79, 95-105.
    • (2005) J. Virol , vol.79 , pp. 95-105
    • Wang, X.1
  • 19
    • 0033618410 scopus 로고    scopus 로고
    • Multiple ras effector pathways contribute to G(1) cell cycle progression
    • Gille,H. et al. (1999) Multiple ras effector pathways contribute to G(1) cell cycle progression. J. Biol. Chem., 274, 22033-22040.
    • (1999) J. Biol. Chem , vol.274 , pp. 22033-22040
    • Gille, H.1
  • 20
    • 0033519453 scopus 로고    scopus 로고
    • Induction of NF-kappaB by the Akt/PKB kinase
    • Kane,L.P. et al. (1999) Induction of NF-kappaB by the Akt/PKB kinase. Curr. Biol., 9, 601-604.
    • (1999) Curr. Biol , vol.9 , pp. 601-604
    • Kane, L.P.1
  • 21
    • 0032911889 scopus 로고    scopus 로고
    • Cyclin D1 expression mediated by phosphatidylinositol 3-kinase through mTOR-p70(S6K)-independent signaling in growth factor-stimulated NIH 3T3 fibroblasts
    • Takuwa,N. et al. (1999) Cyclin D1 expression mediated by phosphatidylinositol 3-kinase through mTOR-p70(S6K)-independent signaling in growth factor-stimulated NIH 3T3 fibroblasts. Mol. Cell Biol., 19, 1346-1358.
    • (1999) Mol. Cell Biol , vol.19 , pp. 1346-1358
    • Takuwa, N.1
  • 22
    • 0036288517 scopus 로고    scopus 로고
    • Differential regulation of cyclins D1 and D3 in hepatocyte proliferation
    • Rickheim,D.G. et al. (2002) Differential regulation of cyclins D1 and D3 in hepatocyte proliferation. Hepatology, 36, 30-38.
    • (2002) Hepatology , vol.36 , pp. 30-38
    • Rickheim, D.G.1
  • 23
    • 33745821637 scopus 로고    scopus 로고
    • Phosphoinositide-dependent kinase 1 targets protein kinase A in a pathway that regulates interleukin 4
    • Nirula,A. et al. (2006) Phosphoinositide-dependent kinase 1 targets protein kinase A in a pathway that regulates interleukin 4. J. Exp. Med., 203, 1733-1744.
    • (2006) J. Exp. Med , vol.203 , pp. 1733-1744
    • Nirula, A.1
  • 24
    • 0030614504 scopus 로고    scopus 로고
    • Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator
    • Perkins,N.D. et al. (1997) Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator. Science, 275, 523-527.
    • (1997) Science , vol.275 , pp. 523-527
    • Perkins, N.D.1
  • 25
    • 0030914691 scopus 로고    scopus 로고
    • CREB-binding protein/p300 are transcriptional coactivators of p65
    • Gerritsen,M.E. et al. (1997) CREB-binding protein/p300 are transcriptional coactivators of p65. Proc. Natl Acad. Sci. USA, 94, 2927-2932.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 2927-2932
    • Gerritsen, M.E.1
  • 26
    • 0032039076 scopus 로고    scopus 로고
    • Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300
    • Zhong,H. et al. (1998) Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300. Mol. Cell, 1, 661-671.
    • (1998) Mol. Cell , vol.1 , pp. 661-671
    • Zhong, H.1
  • 27
    • 0032771498 scopus 로고    scopus 로고
    • Transcriptional activation by NF-kappaB requires multiple coactivators
    • Sheppard,K.A. et al. (1999) Transcriptional activation by NF-kappaB requires multiple coactivators. Mol. Cell Biol., 19 6367-6378.
    • (1999) Mol. Cell Biol , vol.19 , pp. 6367-6378
    • Sheppard, K.A.1
  • 28
    • 0034802887 scopus 로고    scopus 로고
    • The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression
    • Ashburner,B.P. et al. (2001) The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression. Mol. Cell Biol., 21, 7065-7077.
    • (2001) Mol. Cell Biol , vol.21 , pp. 7065-7077
    • Ashburner, B.P.1
  • 29
    • 0036203419 scopus 로고    scopus 로고
    • The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1
    • Zhong,H. et al. (2002) The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1. Mol. Cell, 9, 625-636.
    • (2002) Mol. Cell , vol.9 , pp. 625-636
    • Zhong, H.1
  • 30
    • 0034724681 scopus 로고    scopus 로고
    • Silencing mediator of retinoic acid and thyroid hormone receptors, as a novel transcriptional corepressor molecule of activating protein-1, nuclear factor-kappaB, and serum response factor
    • Lee,S.K. et al. (2000) Silencing mediator of retinoic acid and thyroid hormone receptors, as a novel transcriptional corepressor molecule of activating protein-1, nuclear factor-kappaB, and serum response factor. J. Biol. Chem., 275, 12470-12474.
    • (2000) J. Biol. Chem , vol.275 , pp. 12470-12474
    • Lee, S.K.1
  • 31
    • 33645234941 scopus 로고    scopus 로고
    • PI3-kinase and PDK-1 regulate HDAC1-mediated transcriptional repression of transcription factor NF-kappaB
    • Choi,Y.S. et al. (2005) PI3-kinase and PDK-1 regulate HDAC1-mediated transcriptional repression of transcription factor NF-kappaB. Mol. Cell, 20, 241-246.
    • (2005) Mol. Cell , vol.20 , pp. 241-246
    • Choi, Y.S.1
  • 32
    • 0036535072 scopus 로고    scopus 로고
    • An alternative model of H ferritin promoter transactivation by c-Jun
    • Faniello,M.C. et al. (2002) An alternative model of H ferritin promoter transactivation by c-Jun. Biochem. J., 363, 53-58.
    • (2002) Biochem. J , vol.363 , pp. 53-58
    • Faniello, M.C.1
  • 33
    • 33644698998 scopus 로고    scopus 로고
    • Recruitment of nuclear factor Y to the inverted CCAAT element (ICE) by c-Jun and E1A stimulates basal transcription of the bone sialoprotein gene in osteosarcoma cells
    • Su,M. et al. (2005) Recruitment of nuclear factor Y to the inverted CCAAT element (ICE) by c-Jun and E1A stimulates basal transcription of the bone sialoprotein gene in osteosarcoma cells. J. Biol. Chem., 280, 38365-38375.
    • (2005) J. Biol. Chem , vol.280 , pp. 38365-38375
    • Su, M.1
  • 34
    • 0035953395 scopus 로고    scopus 로고
    • Induction of the AP-1 members c-Jun and JunB by TGF-beta/Smad suppresses early Smad-driven gene activation
    • Verrecchia,F. et al. (2001) Induction of the AP-1 members c-Jun and JunB by TGF-beta/Smad suppresses early Smad-driven gene activation. Oncogene 20, 2205-2211.
    • (2001) Oncogene , vol.20 , pp. 2205-2211
    • Verrecchia, F.1
  • 35
    • 0035816647 scopus 로고    scopus 로고
    • C-Jun binds the N-terminus of humn TAF(II)250 to depress RNA polymerase II transcription in vitro
    • Lively,T.N. et al. (2001) C-Jun binds the N-terminus of humn TAF(II)250 to depress RNA polymerase II transcription in vitro. J. Biol. Chem., 276, 25582-25588.
    • (2001) J. Biol. Chem , vol.276 , pp. 25582-25588
    • Lively, T.N.1
  • 36
    • 2942739039 scopus 로고    scopus 로고
    • The basic leucine zipper domain of c-Jun functions in transcriptional activation through interaction with the N terminus of human TATA-binding protein-associated factor-1 (human TAF(II)250)
    • Lively,T.N. et al. (2004) The basic leucine zipper domain of c-Jun functions in transcriptional activation through interaction with the N terminus of human TATA-binding protein-associated factor-1 (human TAF(II)250). J. Biol. Chem., 279, 26257-26265.
    • (2004) J. Biol. Chem , vol.279 , pp. 26257-26265
    • Lively, T.N.1
  • 37
    • 0028315894 scopus 로고
    • Inducible regulatory elements in the human cyclin D1 promoter
    • Herber,B. et al. (1994) Inducible regulatory elements in the human cyclin D1 promoter. Oncogene, 9, 2105-2107.
    • (1994) Oncogene , vol.9 , pp. 2105-2107
    • Herber, B.1
  • 38
    • 0036098552 scopus 로고    scopus 로고
    • AP-1 as a regulator of cell life and death
    • Shaulian,E. et al. (2002) AP-1 as a regulator of cell life and death. Nat. Cell Biol., 4, E131-E136.
    • (2002) Nat. Cell Biol , vol.4
    • Shaulian, E.1
  • 39
    • 0034637556 scopus 로고    scopus 로고
    • Activation of NF-kappa B by bradykinin through a Galpha(q)- and Gbeta gamma-dependent pathway that involves phosphoinositide kiinase and Akt
    • Xie,P. et al. (2000) Activation of NF-kappa B by bradykinin through a Galpha(q)- and Gbeta gamma-dependent pathway that involves phosphoinositide kiinase and Akt. J. Biol. Chem., 275, 24907-24914.
    • (2000) J. Biol. Chem , vol.275 , pp. 24907-24914
    • Xie, P.1
  • 40
    • 28844449987 scopus 로고    scopus 로고
    • 3-Phosphoinositide-dependent protein kinase-1-mediated IkappaB kinase beta (IkkB) phosphorylation activates NF-kappaB signaling
    • Tanaka,H. et al. (2005) 3-Phosphoinositide-dependent protein kinase-1-mediated IkappaB kinase beta (IkkB) phosphorylation activates NF-kappaB signaling. J. Biol. Chem., 280, 40965-40973.
    • (2005) J. Biol. Chem , vol.280 , pp. 40965-40973
    • Tanaka, H.1
  • 41
    • 0038819943 scopus 로고    scopus 로고
    • Ineffectiveness of histone deacetylase inhibitors to induce apoptosis involves the transcriptional activation of NF-kappa B through the Akt pathway
    • Mayo,M.W. et al. (2003) Ineffectiveness of histone deacetylase inhibitors to induce apoptosis involves the transcriptional activation of NF-kappa B through the Akt pathway. J. Biol. Chem., 278, 18980-18989.
    • (2003) J. Biol. Chem , vol.278 , pp. 18980-18989
    • Mayo, M.W.1
  • 42
    • 33746380872 scopus 로고    scopus 로고
    • Involvement of HDAC1 and the PI3K/PKC signaling pathways in NF-kappaB activation by the HDAC inhibitor apicidin
    • Kim,Y.K. et al. (2006) Involvement of HDAC1 and the PI3K/PKC signaling pathways in NF-kappaB activation by the HDAC inhibitor apicidin. Biochem. Biophys. Res. Commun., 347, 1088-1093.
    • (2006) Biochem. Biophys. Res. Commun , vol.347 , pp. 1088-1093
    • Kim, Y.K.1
  • 43
    • 0037033032 scopus 로고    scopus 로고
    • Phosphorylation of the catalytic subunit of protein kinase A. Autophosphorylation versus phosphorylation by phosphoinositide-dependent kinase-1
    • Moore,M.J. et al. (2002) Phosphorylation of the catalytic subunit of protein kinase A. Autophosphorylation versus phosphorylation by phosphoinositide-dependent kinase-1. J. Biol. Chem., 277, 47878-47884.
    • (2002) J. Biol. Chem , vol.277 , pp. 47878-47884
    • Moore, M.J.1
  • 44
    • 35348858953 scopus 로고    scopus 로고
    • Regulation of hepatitis B virus replication by phosphatidylinositol 3-kinase-AKT signal transduction pathway
    • Guo,H. et al. (2007) Regulation of hepatitis B virus replication by phosphatidylinositol 3-kinase-AKT signal transduction pathway. J. Virol, 81, 10072-10080.
    • (2007) J. Virol , vol.81 , pp. 10072-10080
    • Guo, H.1
  • 45
    • 33846463379 scopus 로고    scopus 로고
    • Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets
    • Boyault,S. et al. (2007) Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets. Hepatology, 45, 42-52.
    • (2007) Hepatology , vol.45 , pp. 42-52
    • Boyault, S.1
  • 46
    • 0035988849 scopus 로고    scopus 로고
    • Activation of NF-kappa B, AP-1 and STAT transcription factors is a frequent and early event in human hepatocellular carcinomas
    • Liu,P. et al. (2002) Activation of NF-kappa B, AP-1 and STAT transcription factors is a frequent and early event in human hepatocellular carcinomas. J. Hepatol., 37, 63-71.
    • (2002) J. Hepatol , vol.37 , pp. 63-71
    • Liu, P.1
  • 47
    • 23044433651 scopus 로고    scopus 로고
    • Protein kinase p-JNK is correlated with the activation of AP-1 and its associated Jun family proteins in hepatocellular carcinoma
    • Guo,L. et al. (2005) Protein kinase p-JNK is correlated with the activation of AP-1 and its associated Jun family proteins in hepatocellular carcinoma. Life Sci., 77, 1869-1878.
    • (2005) Life Sci , vol.77 , pp. 1869-1878
    • Guo, L.1


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