Optimizing selective cerebral perfusion: Deleterious effects of high perfusion pressures

Journal of Thoracic and Cardiovascular Surgery

Volumn 135, Issue 4, 2008, Pages 784-791

  Halstead, James C ^a   Meier, Matthias ^a   Wurm, Michael ^a   Zhang, Ning ^a   Spielvogel, David ^a   Weisz, Donald ^a   Bodian, Carol ^a   Griepp, Randall B ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MICROSPHERE; OXYGEN;

ANIMAL EXPERIMENT; ARTICLE; BRAIN BLOOD FLOW; BRAIN PERFUSION; CARDIOPULMONARY BYPASS; COGNITION; CONTROLLED STUDY; COOLING; EVOKED VISUAL RESPONSE; FEMALE; FLUORESCENCE; HEMATOCRIT; INTRACRANIAL PRESSURE; NONHUMAN; PERFUSION PRESSURE; PH; PIGLET; PRIORITY JOURNAL; SCORING SYSTEM; SWINE; VIDEOTAPE;

ANIMALS; BLOOD PRESSURE; BRAIN; CARDIOPULMONARY BYPASS; CEREBROVASCULAR CIRCULATION; FEMALE; HEMODYNAMICS; INTRACRANIAL HYPERTENSION; INTRACRANIAL PRESSURE; MENTAL DISORDERS; MODELS, ANIMAL; NERVOUS SYSTEM DISEASES; OXYGEN; PERFUSION; SWINE;

EID: 40949087563     PISSN: 00225223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jtcvs.2007.09.035     Document Type: Article

References (25)

1. Di Eusanio M., Schepens M.A., Morshuis W.J., Dossche K.M., Di Bartolomeo R., Pacini D., et al. Brain protection using selective antegrade cerebral perfusion: a multicenter study. Ann Thorac Surg 76 (2003) 1181-1188
2. Strauch J.T., Spielvogel D., Lauten A., Galla J.D., Lansman S.L., McMurtry K., et al. Technical advances in total aortic arch replacement. Ann Thorac Surg 77 (2004) 581-589
3. Lassen N.A. Cerebral blood flow and oxygen consumption in man. Physiol Rev 39 (1959) 183-238
4. Strauch J.T., Spielvogel D., Haldenwang P.L., Zhang N., Weisz D., Bodian C.A., et al. Impact of hypothermic selective cerebral perfusion compared with hypothermic cardiopulmonary bypass on cerebral hemodynamics and metabolism. Eur J Cardiothorac Surg 24 (2003) 807-816
5. Mutch W.A., Sutton I.R., Teskey J.M., Cheang M.S., and Thomson I.R. Cerebral pressure-flow relationship during cardiopulmonary bypass in the dog at normothermia and moderate hypothermia. J Cereb Blood Flow Metab 14 (1994) 510-518
6. Sungurtekin H., Boston U.S., Orszulak T.A., and Cook D.J. Effect of cerebral embolization on regional autoregulation during cardiopulmonary bypass in dogs. Ann Thorac Surg 69 (2000) 1130-1134
7. Baumbach G.L., and Heistad D.D. Cerebral circulation in chronic arterial hypertension. Hypertension 12 (1988) 89-95
8. Howard R., Trend P., and Russell R.W. Clinical features of ischemia in cerebral arterial border zones after periods of reduced cerebral blood flow. Arch Neurol 44 (1987) 934-940
9. O'Dwyer C., Prough D.S., and Johnston W.E. Determinants of cerebral perfusion during cardiopulmonary bypass. J Cardiothorac Vasc Anesth 10 (1996) 54-64
10. Halstead J.C., Spielvogel D., Meier D.M., Weisz D., Bodian C., Zhang N., et al. Optimal pH strategy for selective cerebral perfusion. Eur J Cardiothorac Surg 28 (2005) 266-273
11. Hagl C., Tatton N.A., Weisz D.J., Zhang N., Spielvogel D., Shiang H.H., et al. Cyclosporine A as a potential neuroprotective agent: a study of prolonged hypothermic circulatory arrest in a chronic porcine model. Eur J Cardiothorac Surg 19 (2001) 756-764
12. Strauch J.T., Spielvogel D., Haldenwang P.L., Zhang N., Weisz D., Bodian C.A., et al. Cooling to 10 degrees C and treatment with cyclosporine A improve cerebral recovery following prolonged hypothermic circulatory arrest in a chronic porcine model. Eur J Cardiothorac Surg 27 (2005) 74-80
13. Hagl C., Khaladj N., Weisz D.J., Zhang N., Guo L.J., Bodian C.A., et al. Impact of high intracranial pressure on neurophysiological recovery and behavior in a chronic porcine model of hypothermic circulatory arrest. Eur J Cardiothorac Surg 22 (2002) 510-516
14. Lee J.G., Hudetz A.G., Smith J.J., Hillard C.J., Bosnjak Z.J., and Kampine J.P. The effects of halothane and isoflurane on cerebrocortical microcirculation and autoregulation as assessed by laser-Doppler flowmetry. Anesth Analg 79 (1994) 58-65
15. 2. Anesth Analg 66 (1987) 825-832
16. van der Linden J., Priddy R., Ekroth R., Lincoln C., Pugsley W., Scallan M., et al. Cerebral perfusion and metabolism during profound hypothermia in children. A study of middle cerebral artery ultrasonic variables and cerebral extraction of oxygen. J Thorac Cardiovasc Surg 102 (1991) 103-114
17. Govier A.V., Reves J.G., McKay R.D., Karp R.B., Zorn G.L., Morawetz R.B., et al. Factors and their influence on regional cerebral blood flow during nonpulsatile cardiopulmonary bypass. Ann Thorac Surg 38 (1984) 592-600
18. Plochl W., Cook D.J., Orszulak T.A., and Daly R.C. Critical cerebral perfusion pressure during tepid heart operations in dogs. Ann Thorac Surg 66 (1998) 118-124
19. Schwartz A.E., Sandhu A.A., Kaplon R.J., Young W.L., Jonassen A.E., Adams D.C., et al. Cerebral blood flow is determined by arterial pressure and not cardiopulmonary bypass flow rate. Ann Thorac Surg 60 (1995) 165-170
20. Tanaka J., Shiki K., Asou T., Yasui H., and Tokunaga K. Cerebral autoregulation during deep hypothermic nonpulsatile cardiopulmonary bypass with selective cerebral perfusion in dogs. J Thorac Cardiovasc Surg 95 (1988) 124-132
21. Ohkura K., Kazui T., Yamamoto S., Yamashita K., Terada H., Washiyama N., et al. Comparison of pH management during antegrade selective cerebral perfusion in canine models with old cerebral infarction. J Thorac Cardiovasc Surg 128 (2004) 378-385
22. Tanaka H., Kazui T., Sato H., Inoue N., Yamada O., and Komatsu S. Experimental study on the optimum flow rate and pressure for selective cerebral perfusion. Ann Thorac Surg 59 (1995) 651-657
23. Philpott J.M., Eskew T.D., Sun Y.S., Dennis K.J., Foreman B.H., Fairbrother S.N., et al. A paradox of cerebral hyperperfusion in the face of cerebral hypotension: the effect of perfusion pressure on cerebral blood flow and metabolism during normothermic cardiopulmonary bypass. J Surg Res 77 (1998) 141-149
24. Bozzao L., Fantozzi L.M., Bastianello S., Bozzao A., and Fieschi C. Early collateral blood supply and late parenchymal brain damage in patients with middle cerebral artery occlusion. Stroke 20 (1989) 735-740
25. Dirnagl U., and Pulsinelli W. Autoregulation of cerebral blood flow in experimental focal brain ischemia. J Cereb Blood Flow Metab 10 (1990) 327-336