Impact of high intracranial pressure on neurophysiological recovery and behavior in a chronic porcine model of hypothermic circulatory arrest

European Journal of Cardio-thoracic Surgery

Volumn 22, Issue 4, 2002, Pages 510-516

  Hagl, Christian ^a,b   Khaladj, Nawid ^a   Weisz, Donald J ^a   Zhang, Ning ^a   Guo, Lan Jun ^a   Bodian, Carol A ^a   Spielvogel, David ^a   Griepp, Randall B ^a  

^a NEW YORK UNIVERSITY   (United States)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Cerebral edema; Cerebral protection; Great vessels; Hypothermic circulatory arrest; Intracranial pressure

Indexed keywords

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; BRAIN PROTECTION; CATHETER; CONFERENCE PAPER; CONTROLLED STUDY; CORRELATION ANALYSIS; ELECTROENCEPHALOGRAM; HEART ARREST; HEMODYNAMIC MONITORING; HYPOTHERMIA; INTRACRANIAL PRESSURE; NEUROPHYSIOLOGY; NONHUMAN; OUTCOMES RESEARCH; PARENCHYMA; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; REPERFUSION; STANDARDIZATION; STATISTICAL SIGNIFICANCE;

ANIMALS; BEHAVIOR, ANIMAL; ELECTROENCEPHALOGRAPHY; EVOKED POTENTIALS, SOMATOSENSORY; FEMALE; HEART ARREST, INDUCED; HEMODYNAMIC PROCESSES; INTRACRANIAL HYPERTENSION; MODELS, ANIMAL; REPERFUSION; SWINE; TIME FACTORS;

EID: 0036804418     PISSN: 10107940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1010-7940(02)00380-9     Document Type: Conference Paper

References (20)

1. Burrows F.A., Hillier S.C., McLeod M.E., Iron K.S., Taylor M.J. Anterior fontanel pressure and visual evoked potentials in neonates and infants undergoing profound hypothermic circulatory arrest. Anesthesiology. 73:1990;632-636.
2. van der Linden J. Cerebral hemodynamics after low-flow versus no-flow procedures. Ann Thorac Surg. 59:1995;1321-1325.
3. Jonassen A.E., Quaegebeur J.M., Young W.L. Cerebral blood flow velocity in pediatric patients is reduced after cardiopulmonary bypass with profound hypothermia. J Thorac Cardiovasc Surg. 110:1995;934-943.
4. Morgalla M.H., Mettenleiter H., Bitzer M., Fretschner R., Grote E.H. ICP measurement control: laboratory test of 7 types of intracranial pressure transducers. J Med Eng Technol. 23:1999;144-151.
5. Hagl C., Tatton N.A., Weisz D.J., Zhang N., Spielvogel D., Shiang H.H., Bodian C.A., Griepp R.B., Cyclosporine A. as a potential neuroprotective agent: a study of prolonged hypothermic circulatory arrest in a chronic porcine model. Eur J Cardio-thorac Surg. 19:2001;756-764.
6. Ergin M.A., Galla J.D., Lansman S.L., Quintana C., Bodian C., Griepp R.B. Hypothermic circulatory arrest in operations on the thoracic aorta. Determinants of operative mortality and neurologic outcome. J Thorac Cardiovasc Surg. 107:1994;788-789.
7. Reich D.L., Uysal S., Sliwinski M., Ergin M.A., Kahn R.A., Konstadt S.N., McCullough J., Hibbard M.R., Gordon W.A., Griepp R.B. Neuropsychologic outcome after deep hypothermic circulatory arrest in adults. J Thorac Cardiovasc Surg. 117:1999;156-163.
8. Ergin M.A., Uysal S., Reich D.L., Apaydin A., Lansman S.L., McCullough J.N., Griepp R.B. Temporary neurological dysfunction after deep hypothermic circulatory arrest: a clinical marker of long-term functional deficit. Ann Thorac Surg. 67:1999;1887-1894.
9. Hagl C., Ergin M.A., Galla J.D., Lansman S.L., McCullough J.N., Spielvogel D., Sfeir P., Bodian C.A., Griepp R.B. Neurologic outcome after ascending aorta-aortic arch operations: effect of brain protection technique in high-risk patients. J Thorac Cardiovasc Surg. 121:2001;1107-1121.
10. Juvonen T., Zhang N., Wolfe D., Weisz D.J., Bodian C.A., Shiang H.H., McCullough J.N., Griepp R.B. Retrograde cerebral perfusion enhances cerebral protection during prolonged hypothermic circulatory arrest: a study in a chronic porcine model. Ann Thorac Surg. 66:1998;38-50.
11. Ehrlich M.P., Hagl C., McCullough J., Zhang N., Shiang H.H., Bodian C., Griepp R.B. Retrograde cerebral perfusion provides negligible flow through brain capillaries in the pig. J Thorac Cardiovasc Surg. 122:2001;331-338.
12. Ehrlich M.P., McCullough J., Wolfe D., Zhang N., Shiang H., Weisz D., Bodian C., Griepp R.B. Cerebral effects of cold reperfusion after hypothermic circulatory arrest. J Thorac Cardiovasc Surg. 121:2001;923-931.
13. Tatton N.A., Hagl C., Nandor S., Insolia S., Spielvogel D., Griepp R.B. Apoptotic cell death in the hippocampus due to prolonged hypothermic circulatory arrest: comparison of cyclosporine A, cycloheximide on neuron survival. Eur J Cardio-thorac Surg. 19:2001;746-755.
14. Hagl C., Tatton N.A., Khaladj N., Zhang N., Nandor S., Insolia S., Weisz D.J., Spielvogel D., Griepp R.B. Involvement of apoptosis in neurological injury following hypothermic circulatory arrest: a new target for therapeutic interventions? Ann Thorac Surg. 72:2001;1457-1464.
15. Struber M., Cremer J.T., Gohrbandt B., Hagl C., Jankowski M., Volker B., Ruckoldt H., Martin M., Haverich A. Human cytokine responses to coronary artery bypass grafting with and without cardiopulmonary bypass. Ann Thorac Surg. 68:1999;1330-1335.
16. Guyton R.A. Textbook of medical physiology. 9th ed:1996.
17. Mezrow C.K., Gandsas A., Sadeghi A.M., Midulla P.S., Shiang H.H., Green R., Holzman I.R., Griepp R.B. Metabolic correlates of neurologic and behavioral injury after prolonged hypothermic circulatory arrest. J Thorac Cardiovasc Surg. 109:1995;959-975.
18. Griepp R.B., Ergin M.A., McCullough J.N., Nguyen K.H., Juvonen T., Chang N., Griepp E.B. Use of hypothermic circulatory arrest for cerebral protection during aortic surgery. J Card Surg. 12:1997;312-321.
19. Vath A., Meixensberger J., Dings J., Roosen K. Advanced neuromonitoring including cerebral tissue oxygenation and outcome after traumatic brain injury. Neurol Res. 23:2001;315-320.
20. Shin'oka T., Shum-Tim D., Jonas R.A., Lidov H.G., Laussen P.C., Miura T., du Plessis A. Higher hematocrit improves cerebral outcome after deep hypothermic circulatory arrest. J Thorac Cardiovasc Surg. 112:1996;1610-1621.