Foot-and-Mouth Disease Virus Infection in Fetal Lambs: Tissue Tropism and Cytokine Response

Journal of Comparative Pathology

Volumn 138, Issue 2-3, 2008, Pages 108-120

  Ryan, E ^a   Horsington, J ^a   Brownlie, J ^b   Zhang, Z ^a  

^a INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

^b ROYAL VETERINARY COLLEGE   (United Kingdom)

Author keywords

cytokines; fetus; foot and mouth disease virus; sheep

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; CYTOKINE; GAMMA INTERFERON; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INTERLEUKIN 1ALPHA; MESSENGER RNA; RNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FETUS; FETUS DEATH; FOOT AND MOUTH DISEASE; FOOT AND MOUTH DISEASE VIRUS; GENE EXPRESSION; GENETIC TRANSCRIPTION; HEART MUSCLE; IMMUNE RESPONSE; IN SITU HYBRIDIZATION; INTRAUTERINE INFECTION; LAMB; NONHUMAN; PATHOGENESIS; PLACENTAL TRANSFER; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; SHEEP; SKELETAL MUSCLE; VIRUS DETECTION; VIRUS VIRULENCE;

ANIMALS; ANIMALS, NEWBORN; CYTOKINES; DISEASE MODELS, ANIMAL; DISEASE TRANSMISSION, VERTICAL; FEMALE; FETAL DISEASES; FETUS; FOOT-AND-MOUTH DISEASE; FOOT-AND-MOUTH DISEASE VIRUS; GENE EXPRESSION REGULATION, VIRAL; HEART; IN SITU HYBRIDIZATION; MUSCLE, SKELETAL; MYOCARDIUM; PREGNANCY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, VIRAL; SHEEP; SHEEP DISEASES; TRANSCRIPTION, GENETIC; VIRAL LOAD; VIRUS REPLICATION;

FOOT-AND-MOUTH DISEASE VIRUS; OVIS; OVIS ARIES;

EID: 40849139079     PISSN: 00219975     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcpa.2007.12.001     Document Type: Article

References (27)

1. Alexandersen S., and Donaldson A.I. Further studies to quantify the dose of natural aerosols of foot-and-mouth disease virus for pigs. Epidemiology and Infection 128 (2002) 313-323
2. Alexandersen S., Zhang Z., Donaldson A.I., and Garland A.J.M. The pathogenesis and diagnosis of foot-and-mouth disease. Journal of Comparative Pathology 129 (2003) 1-36
3. Barnett P.V., Keel P., Reid S., Armstrong R.M., Statham R.J., Voyce C., Aggarwal N., and Cox S.J. Evidence that high potency foot-and-mouth disease vaccine inhibits local virus replication and prevents the "carrier" state in sheep. Vaccine 22 (2004) 1221-1232
4. Belsham G.J. Distinctive features of foot-and-mouth disease virus, a member of the picornavirus family; aspects of virus protein synthesis, protein processing and structure. Progress in Biophysics and Molecular Biology 60 (1993) 241-260
5. Brown C.C., Chinsangaram J., and Grubman M.J. Type I interferon production in cattle infected with 2 strains of foot-and-mouth disease virus, as determined by in situ hybridization. Canadian Journal of Veterinary Research 64 (2000) 130-133
6. Brown C.C., Olander H.J., and Meyer R.F. Pathogenesis of foot-and-mouth disease in swine, studied by in situ hybridization. Journal of Comparative Pathology 113 (1995) 51-58
7. Cahill R.N., Kimpton W.G., Washington E.A., and Walker I.D. Origin and development of the gamma delta T-cell system in sheep: a critical role for the thymus in the generation of TcR diversity and tissue tropism. Seminars in Immunology 8 (1996) 351-360
8. Chinsangaram J., Piccone M.E., and Grubman M.J. Ability of foot-and-mouth disease virus to form plaques in cell culture is associated with suppression of alpha/beta interferon. Journal of Virology 73 (1999) 9891-9898
9. Donaldson A.I., Ferris N.P., and Wells G.A. Experimental foot-and-mouth disease in fattening pigs, sows and piglets in relation to outbreaks in the field. Veterinary Record 115 (1984) 509-512
10. Entrican G. Immune regulation during pregnancy and host-pathogen interactions in infectious abortion. Journal of Comparative Pathology 126 (2002) 79-94
11. Horsington J., and Zhang Z. Analysis of foot-and-mouth disease virus replication using strand-specific quantitative RT-PCR. Journal of Virological Methods 144 (2007) 149-155
12. Hughes G.J., Kitching R.P., and Woolhouse M.E. Dose-dependent responses of sheep inoculated intranasally with a type O foot-and-mouth disease virus. Journal of Comparative Pathology 127 (2002) 22-29
13. Ikegami M., Moss T.J., Kallapur S.G., Mulrooney N., Kramer B.W., Nitsos I., Bachurski C.J., Newnham J.P., and Jobe A.H. Minimal lung and systemic responses to TNF-alpha in preterm sheep. American Journal of Physiology. Lung Cellular and Molecular Physiology 285 (2003) L121-L129
14. Kitching R.P., and Hughes G.J. Clinical variation in foot and mouth disease: sheep and goats. Revue Scientifique et Technique de L'Office International des Épizooties 21 (2002) 505-512
15. Ku B.K., Kim S.B., Moon O.K., Lee S.J., Lee J.H., Lyoo Y.S., Kim H.J., and Sur J.H. Role of apoptosis in the pathogenesis of Asian and South American foot-and-mouth disease viruses in swine. Journal of Veterinary Medical Science 67 (2005) 1081-1088
16. de Los Santos T., de Avila Botton S., Weiblen R., and Grubman M.J. The leader proteinase of foot-and-mouth disease virus inhibits the induction of beta interferon mRNA and blocks the host innate immune response. Journal of Virology 80 (2006) 1906-1914
17. McCullagh P. The failure of a combination of thyroid and thymus allografts to prevent the development of autoimmunity in thyroidectomized foetal lambs. Journal of Autoimmunity 6 (1993) 51-62
18. Mulrooney N., Jobe A.H., and Ikegami M. Lung inflammatory responses to intratracheal interleukin-1alpha in ventilated preterm lambs. Pediatric Research 55 (2004) 682-687
19. Prato Murphy M.L., Forsyth M.A., Belsham G.J., and Salt J.S. Localization of foot-and-mouth disease virus RNA by in situ hybridization within bovine tissues. Virus Research 62 (1999) 67-76
20. Rahman A.N., Snibson K.J., Lee C.S., and Meeusen E.N. Effects of implantation and early pregnancy on the expression of cytokines and vascular surface molecules in the sheep endometrium. Journal of Reproductive Immunology 64 (2004) 45-58
21. Ryan E., Zhang Z., Brooks H.W., Horsington J., and Brownlie J. Foot-and-mouth disease virus crosses the placenta and causes death in fetal lambs. Journal of Comparative Pathology 136 (2007) 256-265
22. Ryan, E., Horsington, J., Durand, S., Brooks, H.W., Alexandersen, S., Brownlie, J. and Zhang, Z. Foot-and-mouth disease virus infection in young lambs: pathogenesis and tissue tropism. Veterinary Microbiology, in press. doi:10.1016/j.vetmic.2007.08.029.
23. Saito S. Cytokine network at the feto-maternal interface. Journal of Reproductive Immunology 47 (2000) 87-103
24. Sosenko I.R., Kallapur S.G., Nitsos I., Moss T.J., Newnham J.P., Ikegami M., and Jobe A.H. IL-1alpha causes lung inflammation and maturation by direct effects on preterm fetal lamb lungs. Pediatric Research 60 (2006) 294-298
25. Thompson D., Muriel P., Russell D., Osborne P., Bromley A., Rowland M., Creigh-Tyte S., and Brown C. Economic costs of the foot and mouth disease outbreak in the United Kingdom in 2001. Revue Scientifique et Technique de L'Office International des Épizooties 21 (2002) 675-687
26. Zhang Z., Bashiruddin J.B., Doel C., Horsington J., Durand S., and Alexandersen S. Cytokine and Toll-like receptor mRNAs in the nasal-associated lymphoid tissues of cattle during foot-and-mouth disease virus infection. Journal of Comparative Pathology 134 (2006) 56-62
27. Zhang Z., and Kitching P. A sensitive method for the detection of foot and mouth disease virus by in situ hybridisation using biotin-labelled oligodeoxynucleotides and tyramide signal amplification. Journal of Virological Methods 88 (2000) 187-192