Foot-and-mouth disease virus infection in young lambs: Pathogenesis and tissue tropism

Veterinary Microbiology

Volumn 127, Issue 3-4, 2008, Pages 258-274

  Ryan, Eoin ^a,b   Horsington, Jacquelyn ^a   Durand, Stephanie ^a   Brooks, Harriet ^b   Alexandersen, Soren ^c   Brownlie, Joe ^b   Zhang, Zhidong ^a  

^a INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

^b ROYAL VETERINARY COLLEGE   (United Kingdom)

^c TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

Foot and mouth disease virus; In situ hybridisation; Lamb; Pathogenesis; Sheep

Indexed keywords

VIRUS RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CATTLE; CONTROLLED STUDY; EPIDEMIC; EWE; FOOT AND MOUTH DISEASE; FOOT AND MOUTH DISEASE VIRUS; GENE LOCATION; HISTOPATHOLOGY; IN SITU HYBRIDIZATION; INOCULATION; LAMB; MORTALITY; MYOCARDITIS; NONHUMAN; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SHEEP; SWINE; TEMPERATURE MEASUREMENT; TISSUE SECTION; TONGUE; VIRUS PATHOGENESIS; VIRUS REPLICATION;

ANIMALS; ANIMALS, NEWBORN; ANTIBODIES, VIRAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FOOT-AND-MOUTH DISEASE; FOOT-AND-MOUTH DISEASE VIRUS; HEART; IN SITU HYBRIDIZATION; KINETICS; MUSCLE, SKELETAL; ORGAN SPECIFICITY; RANDOM ALLOCATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, VIRAL; SHEEP; SHEEP DISEASES; TROPISM; VIRAL LOAD; VIRUS REPLICATION;

BOS; FOOT-AND-MOUTH DISEASE VIRUS; FOOT-AND-MOUTH DISEASE VIRUS - TYPE O; OVIS ARIES; SUIDAE;

EID: 38649106737     PISSN: 03781135     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetmic.2007.08.029     Document Type: Article

References (24)

1. Alexandersen S., and Donaldson A.I. Further studies to quantify the dose of natural aerosols of foot-and-mouth disease virus for pigs. Epidemiol. Infect. 128 (2002) 313-323
2. Alexandersen S., Zhang Z., Donaldson A.I., and Garland A.J.M. The pathogenesis and diagnosis of foot-and-mouth disease. J. Comp. Pathol. 129 (2003) 1-36
3. Belsham G.J. Distinctive features of foot-and-mouth disease virus, a member of the picornavirus family; aspects of virus protein synthesis, protein processing and structure. Prog. Biophys. Mol. Biol. 60 (1993) 241-260
4. Burrows R. The persistence of foot-and-mouth disease virus in sheep. J. Hyg. (Camb.) 66 (1968) 633-640
5. Burrows R., Mann J.A., Garland A.J., Greig A., and Goodridge D. The pathogenesis of natural and simulated natural foot-and-mouth disease infection in cattle. J. Comp. Pathol. 91 (1981) 599-609
6. Donaldson A.I., Ferris N.P., and Wells G.A. Experimental foot-and-mouth disease in fattening pigs, sows and piglets in relation to outbreaks in the field. Vet. Rec. 115 (1984) 509-512
7. Ferris N.P., Kitching R.P., Oxtoby J.M., Philpot R.M., and Rendle R. Use of inactivated foot-and-mouth disease virus antigen in liquid-phase blocking ELISA. J. Virol. Methods 29 (1990) 33-41
8. Garcia-Mata E., Federer K.E., Pizzi I., and Aramburu H.G. Pathogenicity of foot and mouth disease virus in different species of unweaned animals. Rev. Vet. Milit. 2 (1954) 205-206
9. Garcia-Mata E., Federer K.E., Pizzi I., and Aramburu H.G. Pathogenicity of foot and mouth disease virus for new-born animals. Gac vet. 17 (1955) 57-64
10. Geering W.G. Foot and mouth disease in sheep. Aust. Vet. J. 43 (1967) 485-489
11. Horsington J., and Zhang Z. Analysis of foot-and-mouth disease virus replication using strand-specific quantitative RT-PCR. J. Virol. Methods 144 (2007) 149-155
12. Hughes G.J., Mioulet V., Kitching R.P., Woolhouse M.E., Alexandersen S., and Donaldson A.I. Foot-and-mouth disease virus infection of sheep: implications for diagnosis and control. Vet. Rec. 150 (2002) 724-727
13. Jubb K.V.F., Kennedy P.C., and Palmer N. Pathology of Domestic Animals. 4th ed. 2 (1993), Academic Press Inc., London 143
14. Khankishiev A.M., Gadshiev K.S., and Alekperov Y.G. Foot and mouth disease in new-born lambs. Veterinariya (Moscow) 35 (1958) 59-60
15. Knowles N.J., and Samuel A.R. Molecular epidemiology of foot-and-mouth disease virus. Virus Res. 91 (2003) 65-80
16. Littlejohn A. FMD in sheep-part 1. State Vet. J. 25 (1970) 3-12
17. Panisup A.S., Kalra D.S., and Chauhan H.V.S. Investigation of an outbreak of FMD in sheep. Haryana Agric. Univ. J. Res. 9 (1979) 111-114
18. Pay T.W.F. FMD in sheep and goats: a review. FMD Bull. 26 (1988) 2-13
19. Quan M., Murphy C.M., Zhang Z., and Alexandersen S. Determinants of early foot-and-mouth disease virus dynamics in pigs. J. Comp. Pathol. 131 (2004) 294-307
20. Reid H.W. FMD in a parturient sheep flock. Vet. Rec. 150 (2002) 791
21. Reid S.M., Ferris N.P., Hutchings G.H., Zhang Z.D., Belsham G.J., and Alexandersen S. Detection of all seven serotypes of foot-and-mouth disease virus by real-time, fluorogenic reverse transcription polymerase chain reaction assay. J. Virol. Methods 105 (2002) 67-80
22. Ryan E., Zhang Z., Brooks H.W., Horsington J., and Brownlie J. Foot-and-mouth disease virus crosses the placenta and causes death in fetal lambs. J. Comp. Pathol. 136 (2007) 256-265
23. Salyi G. Myocarditis in foot and mouth disease of young lambs. Allatorv-Lapok 62 (1939) 159-160
24. Thompson D., Muriel P., Russell D., Osborne P., Bromley A., Rowland M., Creigh-Tyte S., and Brown C. Economic costs of the foot and mouth disease outbreak in the United Kingdom in 2001. Rev. Sci. Technol. Off. Int. Epizoot. 21 (2002) 675-687