Determination of rimantadine in rat plasma by liquid chromatography/electrospray mass spectrometry and its application in a pharmacokinetic study

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 864, Issue 1-2, 2008, Pages 123-128

  Xu, Meijuan ^a   Ju, Wenzheng ^a   Xia, Xiaoyan ^a   Tan, Hengshan ^b   Chen, Min ^a   Zhang, Jun ^a   Xiong, Ningning ^a   Jiang, Meng ^a   Chen, Lei ^a   Gong, Lixiu ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b NANJING GENERAL HOSPITAL OF NANJING MILITARY COMMAND   (China)

Author keywords

Amantadine; LC MS; Pharmacokinetic study; Rimantadine

Indexed keywords

ELECTROSPRAY IONIZATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHARMACOKINETICS; RATS;

CHROMATOGRAPHIC SEPARATION; RAT PLASMA;

BIOASSAY;

RIMANTADINE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG HALF LIFE; DRUG STABILITY; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; LIQUID CHROMATOGRAPHY; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIVIRAL AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; FEMALE; QUALITY CONTROL; RATS; RATS, SPRAGUE-DAWLEY; RIMANTADINE; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

RATTUS;

EID: 40849135368     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2008.01.053     Document Type: Article

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