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Volumn 12, Issue 1, 2008, Pages 93-101

Discovery of virulence factors of pathogenic bacteria

Author keywords

[No Author keywords available]

Indexed keywords

VIRULENCE FACTOR;

EID: 40849126450     PISSN: 13675931     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbpa.2008.01.023     Document Type: Review
Times cited : (193)

References (55)
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    • This is an excellent study solving the crystal structure of FhaC, a member of the Omp85 superfamily involved in the secretion of filamentous hemagglutinin (FHA) in Bordetella pertussis. The structure shows a 16-stranded β barrel that is occluded by an N-terminal α helix and an extracellular loop and two periplasmic POTRA domains structurally resembling those of YaeT.
    • Clantin B., Delattre A.S., Rucktooa P., Saint N., Meli A.C., Locht C., Jacob-Dubuisson F., and Villeret V. Structure of the membrane protein FhaC: a member of the Omp85-TpsB transporter superfamily. Science 317 (2007) 957-961. This is an excellent study solving the crystal structure of FhaC, a member of the Omp85 superfamily involved in the secretion of filamentous hemagglutinin (FHA) in Bordetella pertussis. The structure shows a 16-stranded β barrel that is occluded by an N-terminal α helix and an extracellular loop and two periplasmic POTRA domains structurally resembling those of YaeT.
    • (2007) Science , vol.317 , pp. 957-961
    • Clantin, B.1    Delattre, A.S.2    Rucktooa, P.3    Saint, N.4    Meli, A.C.5    Locht, C.6    Jacob-Dubuisson, F.7    Villeret, V.8
  • 53
    • 35448981857 scopus 로고    scopus 로고
    • Structural basis for evasion of IgA immunity by Staphylococcus aureus revealed in the complex of SSL7 with Fc of human IgA1
    • The authors report the X-ray crystal structure of protein kinase G (PknG) in complex with the inhibitor, AX20017. The structure of PknG consists of a central kinase domain that is flanked by N- and C-terminal rubredoxin and tetratrico-peptide repeat domains, respectively, and the rubredoxin domain is essential for the PknG activity.
    • Ramsland P.A., Willoughby N., Trist H.M., Farrugia W., Hogarth P.M., Fraser J.D., and Wines B.D. Structural basis for evasion of IgA immunity by Staphylococcus aureus revealed in the complex of SSL7 with Fc of human IgA1. Proc Natl Acad Sci U S A 104 (2007) 15051-15056. The authors report the X-ray crystal structure of protein kinase G (PknG) in complex with the inhibitor, AX20017. The structure of PknG consists of a central kinase domain that is flanked by N- and C-terminal rubredoxin and tetratrico-peptide repeat domains, respectively, and the rubredoxin domain is essential for the PknG activity.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 15051-15056
    • Ramsland, P.A.1    Willoughby, N.2    Trist, H.M.3    Farrugia, W.4    Hogarth, P.M.5    Fraser, J.D.6    Wines, B.D.7
  • 54
    • 33646180623 scopus 로고    scopus 로고
    • Solution structure of monomeric BsaL, the type III secretion needle protein of Burkholderia pseudomallei
    • Zhang L., Wang Y., Picking W.L., Picking W.D., and De Guzman R.N. Solution structure of monomeric BsaL, the type III secretion needle protein of Burkholderia pseudomallei. J Mol Biol 359 (2006) 322-330
    • (2006) J Mol Biol , vol.359 , pp. 322-330
    • Zhang, L.1    Wang, Y.2    Picking, W.L.3    Picking, W.D.4    De Guzman, R.N.5
  • 55
    • 33747872707 scopus 로고    scopus 로고
    • Type IV pilus structure by cryo-electron microscopy and crystallography: implications for pilus assembly and functions
    • The Type IV pilus (T4P) structure of N. gonorrhoeae was determined by quantitative fitting of a 2.3 Å full-length pilin crystal structure into a 12.5 Å resolution native T4P solved by cryo-electron microscopy.
    • Craig L., Volkmann N., Arvai A.S., Pique M.E., Yeager M., Egelman E.H., and Tainer J.A. Type IV pilus structure by cryo-electron microscopy and crystallography: implications for pilus assembly and functions. Mol Cell 23 (2006) 651-662. The Type IV pilus (T4P) structure of N. gonorrhoeae was determined by quantitative fitting of a 2.3 Å full-length pilin crystal structure into a 12.5 Å resolution native T4P solved by cryo-electron microscopy.
    • (2006) Mol Cell , vol.23 , pp. 651-662
    • Craig, L.1    Volkmann, N.2    Arvai, A.S.3    Pique, M.E.4    Yeager, M.5    Egelman, E.H.6    Tainer, J.A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.