Stem cells on the brain

Archives of Neurology

Volumn 65, Issue 3, 2008, Pages 311-315

  Knoepfler, Paul S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NERVE PROTEIN; PROTEIN MICROCEPHALIN 1; PROTEIN MICROCEPHALIN 2; PROTEIN MICROCEPHALIN 3; PROTEIN MICROCEPHALIN 4; PROTEIN MICROCEPHALIN 5; PROTEIN MICROCEPHALIN 6; UNCLASSIFIED DRUG;

BRAIN GROWTH; BRAIN SIZE; CHROMATIN; CHROMOSOME ANALYSIS; GENE EXPRESSION; GENE MUTATION; HUMAN; MICROCEPHALY; MUTATIONAL ANALYSIS; NEURAL STEM CELL; NONHUMAN; ONCOGENE C MYB; PREMATURE CHROMOSOME CONDENSATION; PRIORITY JOURNAL; REVIEW;

BRAIN; BRAIN DISEASES; CELL DIFFERENTIATION; HUMANS; NEURONS; STEM CELLS;

EID: 40849102468     PISSN: 00039942     EISSN: 15383687     Source Type: Journal    
DOI: 10.1001/archneur.65.3.311     Document Type: Review

References (17)

1. Tang BL. Molecular genetic determinants of human brain size. Biochem Biophys Res Commun. 2006;345(3):911-916.
2. Jackson AP, McHale DP, Campbell DA, et al. Primary autosomal recessive microcephaly (MCPH1) maps to chromosome 8p22-pter. Am J Hum Genet. 1998;63(2):541-546.
3. Neitzel H, Neumann LM, Schindler D, et al. Premature chromosome condensation in humans associated with microcephaly and mental retardation: a novel autosomal recessive condition. Am J Hum Genet. 2002;70(4):1015- 1022.
4. Trimborn M, Bell SM, Felix C, et al. Mutations in microcephalin cause aberrant regulation of chromosome condensation. Am J Hum Genet. 2004;75(2):261-266.
5. Glover JN, Williams RS, Lee MS. Interactions between BRCT repeats and phosphoproteins: tangled up in two. Trends Biochem Sci. 2004;29(11):579-585.
6. Alderton GK, Galbiati L, Griffith E, et al. Regulation of mitotic entry by microcephalin and its overlap with ATR signalling. Nat Cell Biol. 2006;8(7):725-733.
7. O'Driscoll M, Ruiz-Perez VL, Woods CG, Jeggo PA, Goodship JA. A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome. Nat Genet. 2003;33(4):497-501.
8. Bond J, Roberts E, Springell K, et al. A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size [published correction appears in Nat Genet. 2005;37(5):555]. Nat Genet. 2005;37(4):353-355.
9. Eisenman RN. Deconstructing myc. Genes Dev. 2001;15(16):2023-2030.
10. Kohl NE, Kanda N, Schreck RR, et al. Transposition and amplification of oncogene-related sequences in human neuroblastomas. Cell. 1983;35(2, pt 1):359-367.
11. Lee WH, Murphree AL, Benedict WF. Expression and amplification of the N-myc gene in primary retinoblastoma. Nature. 1984;309(5967):458-460.
12. Tomlinson FH, Jenkins RB, Scheithauer BW, et al. Aggressive medulloblastoma with high-level N-myc amplification. Mayo Clin Proc. 1994;69(4):359-365.
13. Knoepfler PS, Cheng PF, Eisenman RN. N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation. Genes Dev. 2002;16(20):2699-2712.
14. Stanton BR, Perkins AS, Tessarollo L, Sassoon DA, Parada LF. Loss of N-myc function results in embryonic lethality and failure of the epithelial component of the embryo to develop. Genes Dev. 1992;6(12A):2235-2247.
15. Knoepfler PS, Zhang XY, Cheng PF, Gafken PR, McMahon SB, Eisenman RN. Myc influences global chromatin structure. EMBO J. 2006;25(12):2723-2734.
16. van Bokhoven H, Celli J, van Reeuwijk J, et al. MYCN haploinsufficiency is associated with reduced brain size and intestinal atresias in Feingold syndrome. Nat Genet. 2005;37(5):465-467.
17. Tészás A, Meijer R, Scheffer H, et al. Expanding the clinical spectrum of MYCN-related Feingold syndrome. Am J Med Genet A. 2006;140(20):2254-2256.