Reversal of multidrug resistance of gastric cancer cells by downregulation of CIAPIN1 with CIAPIN1 siRNA

Molecular Biology

Volumn 42, Issue 1, 2008, Pages 91-97

  Li, X ^a   Fan, R ^a   Zou, X ^a   Hong, L ^a   Gao, L ^a   Jin, H ^a   Du, R ^a   He, L ^a   Xia, L ^a   Fan, D ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; CIAPIN1; Gastric cancer; Multidrug resistance; RNAi

Indexed keywords

EUKARYOTA;

EID: 40849088081     PISSN: 00268933     EISSN: 16083245     Source Type: Journal    
DOI: 10.1007/s11008-008-1013-7     Document Type: Article

References (20)

1. Lage H., Perlitz C., Abel R. 2001. Enhanced expression of human ABC-transporter tap is associated with cellular resistance to mitoxantrone. FEBS Lett. 503, 179-184.
2. Litman T., Druley T.E., Stein W.D., Bates S.E. 2001. From MDR to MXR: New understanding of multidrug resistance systems, their properties and clinical significance. Cell. Mol. Life Sci. 58, 931-935.
3. Fan K.C., Fan D.M., Cheng L.F., Li C. 2000. Expression of multidrug resistance-related markers in gastric cancer. Anticancer Res. 20, 4809-4814.
4. Kim W.J., Kakehi Y., Wu W.J., et al. 1996. Expression of multidrug resistance-related genes (mdrl, MRP, GST-pi and DNA topoisomerase II) in urothelial cancers. Br. J. Urol. 78, 361-368.
5. Lavie Y., Fiucci G., Liscovitch M. 2001. Upregulation of caveolin in multidrug resistant cancer cells: functional implications. Adv. Drug. Deliv. Rev. 49, 317-323.
6. Fan D., Zhang X., Chen X. 2005. Bird's-eye view on gastric cancer research of the past 25 years. J. Gastroenterol. Hepatol. 20, 360-365.
7. Shibayama H., Takai E., Matsumura I., et al. 2004. Identification of a cytokine-induced antiapoptotic molecule anamorsin essential for definitive hematopoiesis. J. Exp. Med. 4, 581-592.
8. Zhao Y., You H., Liu F., et al. 2002. Differentially expressed gene profiles between multidrug resistant gastric adenocarcinoma cells and their parental cells. Cancer Lett. 185, 211-218.
9. Hao Z., Li X., Qiao T., et al. 2006. CIAPIN1 confers multidrug resistance by upregulating the expression of MDR-1 and MRP-1 in gastric cancer cells. Cancer Biol. Ther. 5, 261-266.
10. Cai X.J., Fan D.M., Zhang X.Y. 1994. Establishment and biological characteristics of MDR human gastric cancer cell line. Chin. J. Clin. Oncol. 2, 67-71.
11. Hao Z., Qiao T., Jin X., et al. 2005. Preparation and characterization of a specific monoclonal antibody against CIAPIN1. Hybridoma. 24, 141-145.
12. Shi Y., Zhai H., Wang X. 2002. Multidrug-resistance-associated protein MGr1-Ag is identical to the human 37-kDa laminin receptor precursor. Cell. Mol. Life Sci. 59, 1577-1583.
13. Guo C., Ding J., Yao L., et al. 2005. Tumor suppressor gene Runx3 sensitizes gastric cancer cells to chemotherapeutic drugs by downregulating Bcl-2, MDR-1 and MRP-1. Int. J. Cancer. 116, 155-160.
14. Perkins C.L., Fang G., Kim C.N., Bhalla K.N. 2000. The role of Apaf-1, caspase-9, and bid proteins in etoposideor paclitaxel-induced mitochondrial events during apoptosis. Cancer Res. 60, 1645-1653.
15. Hao Z., Li X., Qiao T., et al. 2006. Subcellular localization of CIAPIN1. J. Histochem. Cytochem. 54, 1437-1444.
16. Labialle S., Gayet L., Marthinet E., et al. 2002. Transcriptional regulators of the human multidrug resistance 1 gene, recent views. Biochem. Pharmacol. 64, 943-948.
17. Potocnik U., Glavac M.R., Golouh R., Glavac D. 2001. The role of P glycoprotein (MDR1) polymorphisms and mutations in colorectal cancer. Pflugers Arch. 442, R182-R183.
18. Igney F.H., Krammer P.H. 2002. Death and anti-death: Tumour resistance to apoptosis. Nat. Rev. Cancer. 2, 277-288.
19. Sattler M., Liang H., Nettesheim D. 1997. Structure of Bcl-xL-Bak peptide complex: Recognition between regulators of apoptosis. Science. 275, 983-986.
20. Reed J.C. 1999. Dysregulation of apoptosis in cancer. J. Clin. Oncol. 17, 2941-2953.