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Volumn 294, Issue 1, 2008, Pages

Airway smooth muscle relaxation is impaired in mice lacking the p47 phox subunit of NAD(P)H oxidase

Author keywords

Airway responsiveness; Airways; Contractility; Reactive oxygen species

Indexed keywords

ACETYLCHOLINE; METHACHOLINE; OXIDOREDUCTASE; PROTEIN P47; PROTEIN SUBUNIT; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE; UNCLASSIFIED DRUG;

EID: 40749091714     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00384.2007     Document Type: Article
Times cited : (8)

References (51)
  • 1
    • 0033585122 scopus 로고    scopus 로고
    • Mechanism for phosphorylationinduced activation of the phagocyte NADPH oxidase protein p47(phox). Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain-mediated intramolecular interaction in p47(phox), thereby activating the oxidase
    • Ago T, Nunoi H, Ito T, Sumimoto H. Mechanism for phosphorylationinduced activation of the phagocyte NADPH oxidase protein p47(phox). Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain-mediated intramolecular interaction in p47(phox), thereby activating the oxidase. J Biol Chem 274: 33644-33653, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 33644-33653
    • Ago, T.1    Nunoi, H.2    Ito, T.3    Sumimoto, H.4
  • 2
    • 34248204113 scopus 로고    scopus 로고
    • An SS, Bai TR, Bates JH, Black JL, Brown RH, Brusasco V, Chitano P, Deng L, Dowell M, Eidelman DH, Fabry B, Fairbank NJ, Ford LE, Fredberg JJ, Gerthoffer WT, Gilbert SH, Gosens R, Gunst SJ, Halayko AJ, Ingram RH, Irvin CG, James AL, Janssen LJ, King GG, Knight DA, Lauzon AM, Lakser OJ, Ludwig MS, Lutchen KR, Maksym GN, Martin JG, Mauad T, McParland BE, Mijailovich SM, Mitchell HW, Mitchell RW, Mitzner W, Murphy TM, Pare PD, Pellegrino R, Sanderson MJ, Schellenberg RR, Seow CY, Silveira PS, Smith Solway J, Stephens NL, Sterk PJ, Stewart AG, Tang DD, Tepper RS, Tran T, Wang L. Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma. Eur Respir J 29: 834-860, 2007.
    • An SS, Bai TR, Bates JH, Black JL, Brown RH, Brusasco V, Chitano P, Deng L, Dowell M, Eidelman DH, Fabry B, Fairbank NJ, Ford LE, Fredberg JJ, Gerthoffer WT, Gilbert SH, Gosens R, Gunst SJ, Halayko AJ, Ingram RH, Irvin CG, James AL, Janssen LJ, King GG, Knight DA, Lauzon AM, Lakser OJ, Ludwig MS, Lutchen KR, Maksym GN, Martin JG, Mauad T, McParland BE, Mijailovich SM, Mitchell HW, Mitchell RW, Mitzner W, Murphy TM, Pare PD, Pellegrino R, Sanderson MJ, Schellenberg RR, Seow CY, Silveira PS, Smith PG, Solway J, Stephens NL, Sterk PJ, Stewart AG, Tang DD, Tepper RS, Tran T, Wang L. Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma. Eur Respir J 29: 834-860, 2007.
  • 3
    • 0030979811 scopus 로고    scopus 로고
    • Increased hydrogen peroxide and thiobarbituric acid-reactive products in expired breath condensate of asthmatic patients
    • Antczak A, Nowak D, Shariati B, Krol M, Piasecka G, Kurmanowska Z. Increased hydrogen peroxide and thiobarbituric acid-reactive products in expired breath condensate of asthmatic patients. Eur Respir J 10: 1235-1241, 1997.
    • (1997) Eur Respir J , vol.10 , pp. 1235-1241
    • Antczak, A.1    Nowak, D.2    Shariati, B.3    Krol, M.4    Piasecka, G.5    Kurmanowska, Z.6
  • 4
    • 0025977594 scopus 로고
    • Abnormalities in airway smooth muscle in fatal asthma. A comparison between trachea and bronchus
    • Bai TR. Abnormalities in airway smooth muscle in fatal asthma. A comparison between trachea and bronchus. Am Rev Respir Dis 143: 441-443, 1991.
    • (1991) Am Rev Respir Dis , vol.143 , pp. 441-443
    • Bai, T.R.1
  • 6
    • 0033956494 scopus 로고    scopus 로고
    • Effects of superoxide generating systems on muscle tone, cholinergic and NANC responses in cat airway
    • Bauer V, Nakajima T, Pucovsky V, Onoue H, Ito Y. Effects of superoxide generating systems on muscle tone, cholinergic and NANC responses in cat airway. J Auton Nerv Syst 79: 34-44, 2000.
    • (2000) J Auton Nerv Syst , vol.79 , pp. 34-44
    • Bauer, V.1    Nakajima, T.2    Pucovsky, V.3    Onoue, H.4    Ito, Y.5
  • 8
    • 0033538449 scopus 로고    scopus 로고
    • Requirement for reactive oxygen species in serum-induced and platelet-derived growth factor-induced growth of airway smooth muscle
    • Brar SS, Kennedy TP, Whorton AR, Murphy TM, Chitano P, Hoidal JR. Requirement for reactive oxygen species in serum-induced and platelet-derived growth factor-induced growth of airway smooth muscle. J Biol Chem 274: 20017-20026, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 20017-20026
    • Brar, S.S.1    Kennedy, T.P.2    Whorton, A.R.3    Murphy, T.M.4    Chitano, P.5    Hoidal, J.R.6
  • 10
    • 0036082336 scopus 로고    scopus 로고
    • Relaxation of guinea pig trachealis during electrical field stimulation increases with age
    • Chitano P, Cox CM, Murphy TM. Relaxation of guinea pig trachealis during electrical field stimulation increases with age. J Appl Physiol 92: 1835-1842, 2002.
    • (2002) J Appl Physiol , vol.92 , pp. 1835-1842
    • Chitano, P.1    Cox, C.M.2    Murphy, T.M.3
  • 11
    • 0034006633 scopus 로고    scopus 로고
    • Different ontogeny of rate of force generation and shortening velocity in guinea pig trachealis
    • Chitano P, Wang J, Cox CM, Stephens NL, Murphy TM. Different ontogeny of rate of force generation and shortening velocity in guinea pig trachealis. J Appl Physiol 88: 1338-1345, 2000.
    • (2000) J Appl Physiol , vol.88 , pp. 1338-1345
    • Chitano, P.1    Wang, J.2    Cox, C.M.3    Stephens, N.L.4    Murphy, T.M.5
  • 12
    • 35649003935 scopus 로고    scopus 로고
    • Three paradigms of airway smooth muscle hyperresponsiveness in young guinea pigs
    • Chitano P, Wang L, Murphy TM. Three paradigms of airway smooth muscle hyperresponsiveness in young guinea pigs. Can J Physiol Pharmacol 85: 715-726, 2007.
    • (2007) Can J Physiol Pharmacol , vol.85 , pp. 715-726
    • Chitano, P.1    Wang, L.2    Murphy, T.M.3
  • 16
    • 0029937469 scopus 로고    scopus 로고
    • Priming of circulating human eosinophils following late response to allergen challenge
    • Evans DJ, Lindsay MA, O'Connor BJ, Barnes PJ. Priming of circulating human eosinophils following late response to allergen challenge. Eur Respir J 9: 703-708, 1996.
    • (1996) Eur Respir J , vol.9 , pp. 703-708
    • Evans, D.J.1    Lindsay, M.A.2    O'Connor, B.J.3    Barnes, P.J.4
  • 17
    • 0035185240 scopus 로고    scopus 로고
    • Effects of growth factors and extracellular matrix on survival of human airway smooth muscle cells
    • Freyer AM, Johnson SR, Hall IP. Effects of growth factors and extracellular matrix on survival of human airway smooth muscle cells. Am J Respir Cell Mol Biol 25: 569-576, 2001.
    • (2001) Am J Respir Cell Mol Biol , vol.25 , pp. 569-576
    • Freyer, A.M.1    Johnson, S.R.2    Hall, I.P.3
  • 18
    • 0027048411 scopus 로고
    • Mechanism of H2O2-induced modulation of airway smooth muscle
    • Gupta JB, Prasad K. Mechanism of H2O2-induced modulation of airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 263: L714-L722, 1992.
    • (1992) Am J Physiol Lung Cell Mol Physiol , vol.263
    • Gupta, J.B.1    Prasad, K.2
  • 19
    • 0042366348 scopus 로고    scopus 로고
    • Reactive oxygen species and matrix remodeling in diabetic kidney
    • Ha H, Lee HB. Reactive oxygen species and matrix remodeling in diabetic kidney. J Am Soc Nephrol 14: S246-S249, 2003.
    • (2003) J Am Soc Nephrol , vol.14
    • Ha, H.1    Lee, H.B.2
  • 20
    • 0035686459 scopus 로고    scopus 로고
    • Reactive oxygen species as mediators in asthma
    • Henricks PA, Nijkamp FP. Reactive oxygen species as mediators in asthma. Pulm Pharmacol Ther 14: 409-420, 2001.
    • (2001) Pulm Pharmacol Ther , vol.14 , pp. 409-420
    • Henricks, P.A.1    Nijkamp, F.P.2
  • 21
    • 0035194165 scopus 로고    scopus 로고
    • Reactive oxygen species and cell signaling
    • Hoidal JR. Reactive oxygen species and cell signaling. Am J Respir Cell Mol Biol 25: 661-663, 2001.
    • (2001) Am J Respir Cell Mol Biol , vol.25 , pp. 661-663
    • Hoidal, J.R.1
  • 22
    • 0028984840 scopus 로고
    • The p47phox mouse knock-out model of chronic granulomatous disease
    • Jackson SH, Gallin JI, Holland SM. The p47phox mouse knock-out model of chronic granulomatous disease. J Exp Med 182: 751-758, 1995.
    • (1995) J Exp Med , vol.182 , pp. 751-758
    • Jackson, S.H.1    Gallin, J.I.2    Holland, S.M.3
  • 23
    • 34447572685 scopus 로고    scopus 로고
    • Clinical relevance of airway remodelling in airway diseases
    • James AL, Wenzel S. Clinical relevance of airway remodelling in airway diseases. Eur Respir J 30: 134-155, 2007.
    • (2007) Eur Respir J , vol.30 , pp. 134-155
    • James, A.L.1    Wenzel, S.2
  • 24
    • 0026715083 scopus 로고
    • Enhanced production of oxygen radicals in nocturnal asthma
    • Jarjour NN, Busse WW, Calhoun WJ. Enhanced production of oxygen radicals in nocturnal asthma. Am Rev Respir Dis 146: 905-911, 1992.
    • (1992) Am Rev Respir Dis , vol.146 , pp. 905-911
    • Jarjour, N.N.1    Busse, W.W.2    Calhoun, W.J.3
  • 25
    • 0028018792 scopus 로고
    • Enhanced production of oxygen radicals in asthma
    • Jarjour NN, Calhoun WJ. Enhanced production of oxygen radicals in asthma. J Lab Clin Med 123: 131-136, 1994.
    • (1994) J Lab Clin Med , vol.123 , pp. 131-136
    • Jarjour, N.N.1    Calhoun, W.J.2
  • 28
    • 22944438413 scopus 로고    scopus 로고
    • Production and degradation of oxygen metabolites during inflammatory states in the human lung
    • Kinnula VL. Production and degradation of oxygen metabolites during inflammatory states in the human lung. Curr Drug Targets Inflamm Allergy 4: 465-470, 2005.
    • (2005) Curr Drug Targets Inflamm Allergy , vol.4 , pp. 465-470
    • Kinnula, V.L.1
  • 29
    • 0029051473 scopus 로고
    • Generation and disposal of reactive oxygen metabolites in the lung
    • Kinnula VL, Crapo JD, Raivio KO. Generation and disposal of reactive oxygen metabolites in the lung. Lab Invest 73: 3-19, 1995.
    • (1995) Lab Invest , vol.73 , pp. 3-19
    • Kinnula, V.L.1    Crapo, J.D.2    Raivio, K.O.3
  • 30
    • 24644516323 scopus 로고    scopus 로고
    • Airway smooth muscle: A modulator of airway remodeling in asthma
    • quiz 496
    • Lazaar AL, Panettieri RA Jr. Airway smooth muscle: a modulator of airway remodeling in asthma. J Allergy Clin Immunol 116: 488-495; quiz 496, 2005.
    • (2005) J Allergy Clin Immunol , vol.116 , pp. 488-495
    • Lazaar, A.L.1    Panettieri Jr., R.A.2
  • 31
    • 0037040157 scopus 로고    scopus 로고
    • Essential role of the NADPH oxidase subunit p47(phox) in endothelial cell superoxide production in response to phorbol ester and tumor necrosis factor-alpha
    • Li JM, Mullen AM, Yun S, Wientjes F, Brouns GY, Thrasher AJ, Shah AM. Essential role of the NADPH oxidase subunit p47(phox) in endothelial cell superoxide production in response to phorbol ester and tumor necrosis factor-alpha. Circ Res 90: 143-150, 2002.
    • (2002) Circ Res , vol.90 , pp. 143-150
    • Li, J.M.1    Mullen, A.M.2    Yun, S.3    Wientjes, F.4    Brouns, G.Y.5    Thrasher, A.J.6    Shah, A.M.7
  • 34
    • 0030940510 scopus 로고    scopus 로고
    • Enhanced host defense after gene transfer in the murine p47phox-deficient model of chronic granulomatous disease
    • Mardiney M 3rd, Jackson SH, Spratt SK, Li F, Holland SM, Malech HL. Enhanced host defense after gene transfer in the murine p47phox-deficient model of chronic granulomatous disease. Blood 89: 2268-2275, 1997.
    • (1997) Blood , vol.89 , pp. 2268-2275
    • Mardiney 3rd, M.1    Jackson, S.H.2    Spratt, S.K.3    Li, F.4    Holland, S.M.5    Malech, H.L.6
  • 35
    • 26244444476 scopus 로고    scopus 로고
    • Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases
    • Martyn KD, Frederick LM, von Loehneysen K, Dinauer MC, Knaus UG. Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases. Cell Signal 18: 69-82, 2006.
    • (2006) Cell Signal , vol.18 , pp. 69-82
    • Martyn, K.D.1    Frederick, L.M.2    von Loehneysen, K.3    Dinauer, M.C.4    Knaus, U.G.5
  • 36
    • 0031029702 scopus 로고    scopus 로고
    • Role of oxidants in microbial pathophysiology
    • Miller RA, Britigan BE. Role of oxidants in microbial pathophysiology. Clin Microbiol Rev 10: 1-18, 1997.
    • (1997) Clin Microbiol Rev , vol.10 , pp. 1-18
    • Miller, R.A.1    Britigan, B.E.2
  • 37
    • 0023571611 scopus 로고
    • Local parasympathetic mechanisms for ragweed-sensitized canine trachealis hyperresponsiveness
    • Mitchell RW, Kroeger EA, Kepron W, Stephens NL. Local parasympathetic mechanisms for ragweed-sensitized canine trachealis hyperresponsiveness. J Pharmacol Exp Ther 243: 907-914, 1987.
    • (1987) J Pharmacol Exp Ther , vol.243 , pp. 907-914
    • Mitchell, R.W.1    Kroeger, E.A.2    Kepron, W.3    Stephens, N.L.4
  • 38
    • 33748925185 scopus 로고    scopus 로고
    • Bronchial thermoplasty in asthma
    • Mitzner W. Bronchial thermoplasty in asthma. Allergol Int 55: 225-234, 2006.
    • (2006) Allergol Int , vol.55 , pp. 225-234
    • Mitzner, W.1
  • 39
    • 0036708902 scopus 로고    scopus 로고
    • Antioxidants and oxidants regulated signal transduction pathways
    • Owuor ED, Kong AN. Antioxidants and oxidants regulated signal transduction pathways. Biochem Pharmacol 64: 765-770, 2002.
    • (2002) Biochem Pharmacol , vol.64 , pp. 765-770
    • Owuor, E.D.1    Kong, A.N.2
  • 40
    • 33646766449 scopus 로고    scopus 로고
    • Carvedilol inhibits platelet-derived growth factor-induced extracellular matrix synthesis by inhibiting cellular reactive oxygen species and mitogen-activated protein kinase activation
    • Park J, Ha H, Kim MS, Ahn HJ, Huh KH, Kim YS. Carvedilol inhibits platelet-derived growth factor-induced extracellular matrix synthesis by inhibiting cellular reactive oxygen species and mitogen-activated protein kinase activation. J Heart Lung Transplant 25: 683-689, 2006.
    • (2006) J Heart Lung Transplant , vol.25 , pp. 683-689
    • Park, J.1    Ha, H.2    Kim, M.S.3    Ahn, H.J.4    Huh, K.H.5    Kim, Y.S.6
  • 44
    • 0031761532 scopus 로고    scopus 로고
    • Structural and functional changes in the airway smooth muscle of asthmatic subjects
    • Seow CY, Schellenberg RR, Pare PD. Structural and functional changes in the airway smooth muscle of asthmatic subjects. Am J Respir Crit Care Med 158: S179-S186, 1998.
    • (1998) Am J Respir Crit Care Med , vol.158
    • Seow, C.Y.1    Schellenberg, R.R.2    Pare, P.D.3
  • 45
    • 40749134987 scopus 로고    scopus 로고
    • Shute J. Growth factor-extracellular matrix interactions in bronchial tissue in asthma. In: Airway remodeling, edited by Howarth P, Wilson JW, Bousquet J, Rak S, Pawels RA. New York: Marcel Dekker, 2001, p. 245-260.
    • Shute J. Growth factor-extracellular matrix interactions in bronchial tissue in asthma. In: Airway remodeling, edited by Howarth P, Wilson JW, Bousquet J, Rak S, Pawels RA. New York: Marcel Dekker, 2001, p. 245-260.
  • 46
    • 0030940524 scopus 로고    scopus 로고
    • Allergen challenge of passively sensitized human bronchi alters M2 and beta2 receptor function
    • Song P, Milanese M, Crimi E, Rehder K, Brusasco V. Allergen challenge of passively sensitized human bronchi alters M2 and beta2 receptor function. Am J Respir Crit Care Med 155: 1230-1234, 1997.
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 1230-1234
    • Song, P.1    Milanese, M.2    Crimi, E.3    Rehder, K.4    Brusasco, V.5
  • 48
    • 0037151116 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha increases airway smooth muscle oxidants production through a NADPH oxidase-like system to enhance myosin light chain phosphorylation and contractility
    • Thabut G, El-Benna J, Samb A, Corda S, Megret J, Leseche G, Vicaut E, Aubier M, Boczkowski J. Tumor necrosis factor-alpha increases airway smooth muscle oxidants production through a NADPH oxidase-like system to enhance myosin light chain phosphorylation and contractility. J Biol Chem 277: 22814-22821, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 22814-22821
    • Thabut, G.1    El-Benna, J.2    Samb, A.3    Corda, S.4    Megret, J.5    Leseche, G.6    Vicaut, E.7    Aubier, M.8    Boczkowski, J.9
  • 49
    • 0027977024 scopus 로고
    • A modified force-velocity equation for smooth muscle contraction
    • Wang J, Jiang H, Stephens NL. A modified force-velocity equation for smooth muscle contraction. J Appl Physiol 76: 253-258, 1994.
    • (1994) J Appl Physiol , vol.76 , pp. 253-258
    • Wang, J.1    Jiang, H.2    Stephens, N.L.3
  • 50
    • 0022597541 scopus 로고
    • Leukotriene-associated toxic oxygen metabolites induce airway hyperreactivity
    • Weiss EB, Bellino JR. Leukotriene-associated toxic oxygen metabolites induce airway hyperreactivity. Chest 89: 709-716, 1986.
    • (1986) Chest , vol.89 , pp. 709-716
    • Weiss, E.B.1    Bellino, J.R.2


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