-
1
-
-
0018691139
-
Pulmonary hypertension, "plexogenic pulmonary arteriopathy" and the appetite depressant drug aminorex: Post or propter
-
Gurtner H. Pulmonary hypertension, "plexogenic pulmonary arteriopathy" and the appetite depressant drug aminorex: post or propter. Bull Eur Physiopath Res 1979; 15: 897-923.
-
(1979)
Bull Eur Physiopath Res
, vol.15
, pp. 897-923
-
-
Gurtner, H.1
-
2
-
-
0015665898
-
Epidemiologische untersuchungen zum zusammenhang zwischen appetitzueglere innahme und primaer vasculaer pulmonaler hypertonie. [Epidemiologic studies on the relation between use of appetite depressants and primary vascular pulmonary hypertension.]
-
Greiser E. Epidemiologische untersuchungen zum zusammenhang zwischen appetitzueglere innahme und primaer vasculaer pulmonaler hypertonie. [Epidemiologic studies on the relation between use of appetite depressants and primary vascular pulmonary hypertension.] Internist 1973; 14: 437-442.
-
(1973)
Internist
, vol.14
, pp. 437-442
-
-
Greiser, E.1
-
3
-
-
9444287592
-
Appetite-suppressant drugs and the risk of primary pulmonary hypertension
-
Abenhaim L, Moride Y, Brenot F, et al. Appetite-suppressant drugs and the risk of primary pulmonary hypertension. N Engl J Med 1996; 335: 609-616.
-
(1996)
N Engl J Med
, vol.335
, pp. 609-616
-
-
Abenhaim, L.1
Moride, Y.2
Brenot, F.3
-
4
-
-
40649100110
-
Pulmonary arterial hypertension associated with fenfluramine exposure: Report of 109 cases
-
Souza R, Humbert M, Sztrymf B, et al. Pulmonary arterial hypertension associated with fenfluramine exposure: report of 109 cases. Eur Respir J 2008; 31: 343-348.
-
(2008)
Eur Respir J
, vol.31
, pp. 343-348
-
-
Souza, R.1
Humbert, M.2
Sztrymf, B.3
-
5
-
-
0033623296
-
Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-b family
-
Thompson J, Machado R, Pauciulo M, et al. Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-b family. J Med Genet 2003; 37: 741-745.
-
(2003)
J Med Genet
, vol.37
, pp. 741-745
-
-
Thompson, J.1
Machado, R.2
Pauciulo, M.3
-
6
-
-
0031551969
-
Cardiac valuvulopathy associated with exposure to fenfluramine or dexfenfluramine: US Department of Health and Human Services interim public health recommendations, November 1997
-
From the Centers for Disease Control and Prevention
-
From the Centers for Disease Control and Prevention. Cardiac valuvulopathy associated with exposure to fenfluramine or dexfenfluramine: US Department of Health and Human Services interim public health recommendations, November 1997. JAMA 1997; 278: 1729-1731.
-
(1997)
JAMA
, vol.278
, pp. 1729-1731
-
-
-
7
-
-
20144389923
-
Long-term serotonin administration induces heart valve disease in rats
-
Gustafsson B, Tømmerås K, Nordrum I, et al. Long-term serotonin administration induces heart valve disease in rats. Circulation 2005; 111: 1517-1522.
-
(2005)
Circulation
, vol.111
, pp. 1517-1522
-
-
Gustafsson, B.1
Tømmerås, K.2
Nordrum, I.3
-
8
-
-
0033989494
-
Possible role of valvular serotonin 5-HT(2B) receptors in the cardiopathy associated with fenfluramine
-
Fitzgerald L, Burn T, Brown B, et al. Possible role of valvular serotonin 5-HT(2B) receptors in the cardiopathy associated with fenfluramine. Mol Pharmacol 2000; 57: 75-81.
-
(2000)
Mol Pharmacol
, vol.57
, pp. 75-81
-
-
Fitzgerald, L.1
Burn, T.2
Brown, B.3
-
9
-
-
33644865941
-
Deficiency of the 5-hydroxytryptamine transporter gene leads to cardiac fibrosis and valvulopathy in mice
-
Mekontso-Dessap A, Brouri F, Pascal O, et al. Deficiency of the 5-hydroxytryptamine transporter gene leads to cardiac fibrosis and valvulopathy in mice. Circulation 2006; 113: 81-89.
-
(2006)
Circulation
, vol.113
, pp. 81-89
-
-
Mekontso-Dessap, A.1
Brouri, F.2
Pascal, O.3
-
10
-
-
0028018831
-
Effects of chronic treatment with dexfenfluramine on serotonin in rat blood, brain and lung tissue
-
Celada P, Martín F, Artigas F. Effects of chronic treatment with dexfenfluramine on serotonin in rat blood, brain and lung tissue. Life Sci 1994; 55: 1237-1243.
-
(1994)
Life Sci
, vol.55
, pp. 1237-1243
-
-
Celada, P.1
Martín, F.2
Artigas, F.3
-
11
-
-
0031956562
-
Effect of dexfenfluarmine treatment in rats exposed to acute and chronic hypoxia
-
Eddahibi S, Raffestin B, Launay J, Sitbon M, Adnot S. Effect of dexfenfluarmine treatment in rats exposed to acute and chronic hypoxia. Am J Respir Crit Care Med 1998; 157: 1111-1119.
-
(1998)
Am J Respir Crit Care Med
, vol.157
, pp. 1111-1119
-
-
Eddahibi, S.1
Raffestin, B.2
Launay, J.3
Sitbon, M.4
Adnot, S.5
-
12
-
-
33745947405
-
Amphetamine analogs increase plasma serotonin: Implications for cardiac and pulmonary disease
-
Zolkowska D, Rothman R, Baumann M. Amphetamine analogs increase plasma serotonin: implications for cardiac and pulmonary disease. J Pharmacol Exp Ther 2006; 318: 604-610.
-
(2006)
J Pharmacol Exp Ther
, vol.318
, pp. 604-610
-
-
Zolkowska, D.1
Rothman, R.2
Baumann, M.3
-
13
-
-
20344365090
-
Serotonin transporter inhibition prevents and reverses monocrotaline-induced pulmonary hypertension in rats
-
Guignabert C, Raffestin B, Benferhat R, et al. Serotonin transporter inhibition prevents and reverses monocrotaline-induced pulmonary hypertension in rats. Circulation 2005; 111: 2812-2819.
-
(2005)
Circulation
, vol.111
, pp. 2812-2819
-
-
Guignabert, C.1
Raffestin, B.2
Benferhat, R.3
-
14
-
-
33745915236
-
Selective serotonin reuptake inhibitor use and outcomes in pulmonary arterial hypertension
-
Kawut S, Horn E, Berekashvili K, et al. Selective serotonin reuptake inhibitor use and outcomes in pulmonary arterial hypertension. Pulm Pharmacol Ther 2006; 19: 370-374.
-
(2006)
Pulm Pharmacol Ther
, vol.19
, pp. 370-374
-
-
Kawut, S.1
Horn, E.2
Berekashvili, K.3
-
15
-
-
1542440233
-
The effect of the anorectic agent, d-fenfluramine, and its primary metabolite, d-norfenfluramine, on intact human platelet serotonin uptake and efflux
-
Johnson G, Leis L, Dunlop P, Weir E. The effect of the anorectic agent, d-fenfluramine, and its primary metabolite, d-norfenfluramine, on intact human platelet serotonin uptake and efflux. J Thromb Haemost 2003; 1: 2663-2668.
-
(2003)
J Thromb Haemost
, vol.1
, pp. 2663-2668
-
-
Johnson, G.1
Leis, L.2
Dunlop, P.3
Weir, E.4
-
16
-
-
0029033224
-
Increased plasma serotonin in primary pulmonary hypertension
-
Herve P, Launay J, Scrobohaci M, et al. Increased plasma serotonin in primary pulmonary hypertension. Am J Med 1995; 99: 249-254.
-
(1995)
Am J Med
, vol.99
, pp. 249-254
-
-
Herve, P.1
Launay, J.2
Scrobohaci, M.3
-
17
-
-
33847688879
-
Effect of tryptophan hydroxylase 1 deficiency on the development of hypoxia-induced pulmonary hypertension
-
Morecroft I, Dempsie Y, Bader M, et al. Effect of tryptophan hydroxylase 1 deficiency on the development of hypoxia-induced pulmonary hypertension. Hypertension 2007; 49: 232-236.
-
(2007)
Hypertension
, vol.49
, pp. 232-236
-
-
Morecroft, I.1
Dempsie, Y.2
Bader, M.3
-
18
-
-
35348842184
-
Tryptophan hydroxylase 1 knockout and tryptophan hydroxylase 2 polymorphism: Effects on hypoxic pulmonary hypertension in mice
-
Izikki M, Hanoun N, Marcos E, et al. Tryptophan hydroxylase 1 knockout and tryptophan hydroxylase 2 polymorphism: effects on hypoxic pulmonary hypertension in mice. Am J Physiol 2007; 293: L1045-L1052.
-
(2007)
Am J Physiol
, vol.293
-
-
Izikki, M.1
Hanoun, N.2
Marcos, E.3
-
19
-
-
0032971293
-
Induction of serotonin transporter by hypoxia in pulmonary vascular smooth muscle cells. Relationship with the mitogenic action of serotonin
-
Eddahibi S, Fabre V, Boni C, et al. Induction of serotonin transporter by hypoxia in pulmonary vascular smooth muscle cells. Relationship with the mitogenic action of serotonin. Circ Res 1999; 84: 329-336.
-
(1999)
Circ Res
, vol.84
, pp. 329-336
-
-
Eddahibi, S.1
Fabre, V.2
Boni, C.3
-
20
-
-
0034096980
-
Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene
-
Eddahibi S, Hanoun N, Lanfumey L, et al. Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene. J Clin Invest 2000; 105: 1555-1562.
-
(2000)
J Clin Invest
, vol.105
, pp. 1555-1562
-
-
Eddahibi, S.1
Hanoun, N.2
Lanfumey, L.3
-
21
-
-
2442519344
-
Over-expression of the 5-hydroxytryptamine transporter gene: Effect on pulmonary haemodynamics and hypoxia-induced pulmonary hypertension
-
MacLean M, Deuchar G, Hicks M, et al. Over-expression of the 5-hydroxytryptamine transporter gene: effect on pulmonary haemodynamics and hypoxia-induced pulmonary hypertension. Circulation 2004; 109: 2150-2155.
-
(2004)
Circulation
, vol.109
, pp. 2150-2155
-
-
MacLean, M.1
Deuchar, G.2
Hicks, M.3
-
22
-
-
0028158826
-
Serotonin produces both hyperplasia and hypertrophy of bovine pulmonary artery smooth muscle cells in culture
-
Lee S, Weng W, Lanzillo J, Fanburg B. Serotonin produces both hyperplasia and hypertrophy of bovine pulmonary artery smooth muscle cells in culture. Am J Physiol 1994; 266: L46-L52.
-
(1994)
Am J Physiol
, vol.266
-
-
Lee, S.1
Weng, W.2
Lanzillo, J.3
Fanburg, B.4
-
23
-
-
0033600538
-
Aminorex, fenfluramine and chlorphentermine are serotonin transporter substrates. Implications for primary pulmonary hypertension
-
Rothman R, Ayestas M, Dersch C, Baumann M. Aminorex, fenfluramine and chlorphentermine are serotonin transporter substrates. Implications for primary pulmonary hypertension. Circulation 1999; 100: 869-875.
-
(1999)
Circulation
, vol.100
, pp. 869-875
-
-
Rothman, R.1
Ayestas, M.2
Dersch, C.3
Baumann, M.4
-
24
-
-
0035347399
-
Dexfenfluramine as a mitogen signals through the formation of superoxide anion
-
Lee S, Wang W, Fanburg B. Dexfenfluramine as a mitogen signals through the formation of superoxide anion. FASEB J 2001; 15: 1324-1325.
-
(2001)
FASEB J
, vol.15
, pp. 1324-1325
-
-
Lee, S.1
Wang, W.2
Fanburg, B.3
-
25
-
-
0034776773
-
Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension
-
Eddahibi S, Humbert M, Fadel E, et al. Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension. J Clin Invest 2001; 108: 1141-1150.
-
(2001)
J Clin Invest
, vol.108
, pp. 1141-1150
-
-
Eddahibi, S.1
Humbert, M.2
Fadel, E.3
-
26
-
-
33646201514
-
Cross talk between endothelial and smooth muscle cells in pulmonary hypertension: Critical role for serotonin-induced smooth muscle hyperplasia
-
Eddahibi S, Guignaber C, Barlier-Mur A, et al. Cross talk between endothelial and smooth muscle cells in pulmonary hypertension: critical role for serotonin-induced smooth muscle hyperplasia. Circulation 2006; 113: 1857-1864.
-
(2006)
Circulation
, vol.113
, pp. 1857-1864
-
-
Eddahibi, S.1
Guignaber, C.2
Barlier-Mur, A.3
-
27
-
-
30144440754
-
Serotonin transporter and receptors in various forms of human pulmonary hypertension
-
Marcos E, Fadel E, Sanchez O, et al. Serotonin transporter and receptors in various forms of human pulmonary hypertension. Chest 2005; 128: Suppl. 6, 552S-553S.
-
(2005)
Chest
, vol.128
, Issue.SUPPL. 6
-
-
Marcos, E.1
Fadel, E.2
Sanchez, O.3
-
28
-
-
0036799278
-
Function of the serotonin 5-hydroxytryptamine 2B receptor in pulmonary hypertension
-
Launay J, Hervé P, Peoc'h K, et al. Function of the serotonin 5-hydroxytryptamine 2B receptor in pulmonary hypertension. Nat Med 2002; 8: 1129-1135.
-
(2002)
Nat Med
, vol.8
, pp. 1129-1135
-
-
Launay, J.1
Hervé, P.2
Peoc'h, K.3
-
29
-
-
4644248958
-
Rho kinase-induced nuclear translocation of ERK1/ERK2 in smooth muscle cell mitogenesis caused by serotonin
-
Liu Y, Suzuki Y, Day R, Fanburg B. Rho kinase-induced nuclear translocation of ERK1/ERK2 in smooth muscle cell mitogenesis caused by serotonin. Circ Res 2004; 95: 579-586.
-
(2004)
Circ Res
, vol.95
, pp. 579-586
-
-
Liu, Y.1
Suzuki, Y.2
Day, R.3
Fanburg, B.4
-
30
-
-
0029825291
-
Anorexic agents aminorex, fenfluramine, and dexfenfluramine inhibit potassium current in rat pulmonary vascular smooth muscle and cause pulmonary vasoconstriction
-
Weir E, Reeve H, Huang J, et al. Anorexic agents aminorex, fenfluramine, and dexfenfluramine inhibit potassium current in rat pulmonary vascular smooth muscle and cause pulmonary vasoconstriction. Circulation 1996; 94: 2216-2220.
-
(1996)
Circulation
, vol.94
, pp. 2216-2220
-
-
Weir, E.1
Reeve, H.2
Huang, J.3
-
31
-
-
1242306799
-
Nordexfenfluramine causes more severe pulmonary vasoconstriction than dexfenfluramine
-
Hong Z, Olschewski A, Reeve H, Nelson D, Hong F, Weir E. Nordexfenfluramine causes more severe pulmonary vasoconstriction than dexfenfluramine. Am J Physiol 2003; 286: L531-L538.
-
(2003)
Am J Physiol
, vol.286
-
-
Hong, Z.1
Olschewski, A.2
Reeve, H.3
Nelson, D.4
Hong, F.5
Weir, E.6
-
32
-
-
0035008770
-
Alterations in a redox oxygen sensing mechanism in chronic hypoxia
-
Reeve H, Michelakis E, Nelson D, Weir E, Archer S. Alterations in a redox oxygen sensing mechanism in chronic hypoxia. J Appl Physiol 2001; 90: 2249-2256.
-
(2001)
J Appl Physiol
, vol.90
, pp. 2249-2256
-
-
Reeve, H.1
Michelakis, E.2
Nelson, D.3
Weir, E.4
Archer, S.5
-
33
-
-
33745155785
-
An abnormal mitochondrial -HIF1a - Kv channel pathway disrupts oxygen-sensing and triggers pulmonary arterial hypertension (PAH) in fawn-hooded rats: Similarities to human PAH
-
Bonnet S, Michelakis E, Porter C, et al. An abnormal mitochondrial -HIF1a - Kv channel pathway disrupts oxygen-sensing and triggers pulmonary arterial hypertension (PAH) in fawn-hooded rats: similarities to human PAH. Circulation 2006; 113: 2630-2641.
-
(2006)
Circulation
, vol.113
, pp. 2630-2641
-
-
Bonnet, S.1
Michelakis, E.2
Porter, C.3
-
34
-
-
0032491187
-
+ channels in pulmonary artery smooth muscle cells of patients with primary pulmonary hypertension
-
+ channels in pulmonary artery smooth muscle cells of patients with primary pulmonary hypertension. Circulation 1998; 98: 1400-1406.
-
(1998)
Circulation
, vol.98
, pp. 1400-1406
-
-
Yuan, J.1
Aldinger, B.2
Juhaszova, M.3
-
36
-
-
6344285402
-
Increased release of serotonin from rat ileum due to dexfenfluramine
-
Rezaie-Majd S, Murar J, Nelson D, et al. Increased release of serotonin from rat ileum due to dexfenfluramine. Am J Physiol 2004; 287: R1209-R1213.
-
(2004)
Am J Physiol
, vol.287
-
-
Rezaie-Majd, S.1
Murar, J.2
Nelson, D.3
-
37
-
-
33744970745
-
Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension
-
Guignabert C, Izikki M, Tu L, et al. Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension. Circ Res 2006; 98: 1323-1330.
-
(2006)
Circ Res
, vol.98
, pp. 1323-1330
-
-
Guignabert, C.1
Izikki, M.2
Tu, L.3
-
38
-
-
33646145730
-
Serotonin inhibits voltage-gated K+ currents in pulmonary artery smooth muscle cells: Role of 5-HT2A receptors, caveolin-1 and Kv1.5 channel internalization
-
Cogolludo A, Moreno L, Lodi F, et al. Serotonin inhibits voltage-gated K+ currents in pulmonary artery smooth muscle cells: role of 5-HT2A receptors, caveolin-1 and Kv1.5 channel internalization. Circ Res 2006; 98: 931-938.
-
(2006)
Circ Res
, vol.98
, pp. 931-938
-
-
Cogolludo, A.1
Moreno, L.2
Lodi, F.3
-
39
-
-
33751087216
-
Bone morphogenetic protein-2 upregulates expression and function of voltage-gated K+ channels in human pulmonary artery smooth muscle cells
-
Fantozzi I, Platoshyn O, Wong A, et al. Bone morphogenetic protein-2 upregulates expression and function of voltage-gated K+ channels in human pulmonary artery smooth muscle cells. Am J Physiol 2006; 291: L993-L1004.
-
(2006)
Am J Physiol
, vol.291
-
-
Fantozzi, I.1
Platoshyn, O.2
Wong, A.3
|