Expression of protein gene product 9.5, tyrosine hydroxylase and serotonin in the pineal gland of rats with streptozotocin-induced diabetes

Neuroscience Research

Volumn 60, Issue 3, 2008, Pages 233-243

  Tsai, Mang Hung ^a   Wei, I Hua ^a   Jiang Shieh, Ya Fen ^b   Jou, Ming Jia ^a   Ko, Miau Hwa ^a   Chen, Hui Min ^c   Wu, Ching Hsiang ^d  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c School of Medicine   (Taiwan)

^d NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

Author keywords

Diabetes; Immunohistochemistry; Morphometric; PGP 9.5; Pineal; Serotonin; Tyrosine hydroxylase

Indexed keywords

GENE PRODUCT; MELATONIN; NORADRENALIN; SEROTONIN; STREPTOZOCIN; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASEMENT MEMBRANE; BIOSYNTHESIS; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC NEUROPATHY; ENZYME ACTIVITY; FEMALE; HORMONE ACTION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; NONHUMAN; PINEAL BODY; PINEALOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SCHWANN CELL; SYMPATHETIC INNERVATION;

ANIMALS; BIOLOGICAL MARKERS; DIABETES MELLITUS, EXPERIMENTAL; FEMALE; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY, ELECTRON; NERVE FIBERS, UNMYELINATED; PINEAL GLAND; RATS; RATS, WISTAR; SEROTONIN; SYMPATHETIC NERVOUS SYSTEM; TYROSINE 3-MONOOXYGENASE; UBIQUITIN THIOLESTERASE;

EID: 40649119459     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neures.2007.11.003     Document Type: Article

References (42)

1. Anderson L.C., Suleiman A.H., and Garrett J.R. Morphological effects of diabetes on the granular ducts and acini of the rat submandibular gland. Microsc. Res. Tech. 27 (1994) 61-70
2. Appenzeller O., and Richardson Jr. E.P. The sympathetic chain in patients with diabetic and alcoholic polyneuropathy. Neurology 16 (1966) 1205-1209
3. Aughsteen A.A., Khair A.M., and Suleiman A.A. Quantitative morphometric study of the skeletal muscles of normal and streptozotocin-diabetic rats. JOP 7 (2006) 382-389
4. Barber M., Kasturi B., Austin M.E., Patel K.P., MohanKumar S.M., and MohanKumar P.S. Diabetes-induced neuroendocrine changes in rats: role of brain monoamines, insulin and leptin. Brain Res. 964 (2003) 128-135
5. Bitar M., Koulu M., Rapoport S.I., and Linnoila M. Diabetes-induced alteration in brain monoamine metabolism in rats. J. Pharmacol. Exp. Ther. 236 (1986) 432-437
6. Champney T.H., Holtorf A.P., Craft C.M., and Reiter R.J. Hormonal modulation of pineal melatonin synthesis in rats and Syrian hamsters: effects of streptozotocin-induced diabetes and insulin injections. Comp. Biochem. Physiol. A 83 (1986) 391-395
7. Changrani N.R., Chonkar A., Adeghate E., and Singh J. Effects of streptozotocin- induced type 1 diabetes mellitus on total protein concentrations and cation contents in the isolated pancreas, parotid, submandibular and lacrimal glands of rats. Ann. N.Y. Acad. Sci. 1084 (2006) 503-519
8. Cutler L.S., Pinney H.E., Christian C., and Russotto S.B. Ultrastructural studies of the rat submandibular gland in streptozotocin-induced diabetes mellitus. Virchows Arch. A: Pathol. Anat. Histol. 382 (1979) 301-311
9. Duchen L.W., Anjorin A., Watkins P.J., and Mackay J.D. Pathology of autonomic neuropathy in diabetes mellitus. Ann. Intern. Med. 92 (1980) 301-303
10. Ewing D.J., and Clarke B.F. Diabetic autonomic neuropathy: present insights and future prospects. Diabetes Care 9 (1986) 648-665
11. Gallyas F., Görcs T., and Merchenthaler I. High-grade intensification of the end product of the diaminobenzidine reaction for peroxidase histochemistry. J. Histochem. Cytochem. 30 (1982) 183-191
12. Goldman B.D., and Nelson R.J. Melatonin and seasonality in mammals. In: Yu H.S., and Reiter R.J. (Eds). Melatonin: Biosynthesis, Physiological Effects and Clinical Applications (1993), CRC, Boca Raton pp. 225-252
13. Gundersen H.J.G., and Jensson E.B. The efficiency of systematic sampling in stereology and in prediction. J. Microsc. 147 (1987) 229-263
14. Hasegawa Y., Suehiro A., Higasa S., Namba M., and Kakishita E. Enhancing effect of advanced glycation end products on serotonin-induced platelet aggregation in patients with diabetes mellitus. Thromb. Res. 107 (2002) 319-323
15. Ivy G.O., Kitani K., and Ihara Y. Anomalous accumulation of tau and ubiquitin immunoreactivities in rat brain caused by inhibition in normal aging: a clue to PHF pathogensis?. Brain Res. 498 (1989) 360-365
16. Jiang-Shieh Y.F., Wu C.H., Chien H.F., Wei I.H., Chang M.L., Shieh J.Y., and Wen C.Y. Reactive changes of interstitial glia and pinealocytes in the rat pineal gland challenged with cell wall components from gram-positive and -negative bacteria. J. Pineal Res. 38 (2005) 17-26
17. Lackvić Z., Šalković M., Kuci Z., and Relja M. Effect of long-lasting diabetes mellitus on rat and human brain monoamines. J. Neurochem. 54 (1990) 143-147
18. Lauria G., McArthur J.C., Hauer P.E., Griffin J.W., and Cornblath D.R. Neuropathological alterations in diabetic truncal neuropathy: evaluation by skin biopsy. J. Neurol. Neurosurg. Psychiatry 65 (1998) 762-766
19. Liu C., and Shu C. Morphological studies of the adrenal zona glomerulosa cells and the thyroid and pituitary glands in streptozotocin-induced experimental diabetic rats. Zhonghua Bing Li Xue Za Zhi 25 (1996) 358-360
20. Mackenzie R.G., and Trulson M.E. Effects of insulin and streptozotocin-induced diabetes on brain tryptophan and serotonin metabolism in rats. J. Neurochem. 30 (1978) 205-211
21. Mastsushima S., and Reiter R.J. Fine structural features of adrenergic nerve fibers and ending in the pineal gland of the rat, ground squirrel and chinchilla. Am. J. Anat. 148 (1977) 463-477
22. Mooradian A.D. Diabetic complications of the central nervous system. Endocr. Rev. 9 (1988) 346-356
23. Neff N.H., Barrett R.E., and Costa E. Kinetic and fluorescent histochemical analysis of the serotonin compartments in rat pineal gland. Eur. J. Pharmacol. 5 (1969) 348-356
24. Noorafshan A. Volume-weighted mean volume of the submandibular gland acini in male and female diabetic rats. Micron 37 (2006) 613-616
25. O'Brien I.A., Lewin I.G., O'Hare J.P., Arendt J., and Corrall R.J. Abnormal circadian rhythm of melatonin in diabetic autonomic neuropathy. Clin. Endocrinol. (Oxf.) 24 (1986) 359-364
26. Pang S.F., Tang F., and Tang P.L. Alloxan-induced diabetes and the pineal gland: differential effects on the levels of pineal N-acetylserotonin, pineal melatonin and serum melatonin. J. Pineal Res. 2 (1985) 79-85
27. Peschke E., Frese T., Chankiewitz E., Peschke D., Preiss U., Schneyer U., Spessert R., and Muhlbauer F. Diabetic Goto Kakizaki rats as well as type 2 diabetic patients show a decreased diurnal serum melatonin level and an increased pancreatic melatonin-receptor status. J. Pineal Res. 40 (2006) 135-143
28. Pittenger G.L., Ray M., Burcus N.I., McNulty P., Basta B., and Vinik A.I. Intraepidermal nerve fibers are indicators of small-fiber neuropathy in both diabetic and nondiabetic patients. Diabetes Care 27 (2004) 1974-1979
29. Redecker P., Cetin Y., and Korf H.W. Differential immunocytochemical localization of calretinin in the pineal gland of three mammalian species. J. Neurocytol. 25 (1996) 9-18
30. Reiter R.J. Pineal melatonin: cell biology of its synthesis and of its physiological interaction. Endocr. Rev. 12 (1991) 151-180
31. Rode J., Dhillon A.P., Doran J.F., Jackson P., and Thompson R.J. PGP 9.5: a new marker for human neuroendocrine tumors. Histopathology 9 (1985) 147-158
32. Romeo H.E., Weihe E., Müller S., and Vollrath L. Protein gene product (PGP 9.5) immunoreactivity in nerve fibers and pinealocytes of guinea-pig pineal gland: interrelationship with tyrosine-hydroxylase and neuropeptide-Y-immunoreactive nerve fibers. Cell Tissue Res. 271 (1993) 477-484
33. Russell J.W., Sullivan K.A., Windebank A.J., Herrmann D.N., and Feldman E.L. Neurons undergo apoptosis in animal and cell culture models of diabetes. Neurobiol. Dis. 6 (1999) 347-363
34. Schmidt R.E. Neuronal preservation in the sympathetic ganglia of rats with chronic streptozotocin-induced diabetes. Brain Res. 921 (2001) 256-259
35. Schmidt R.E., and Cogswell B.E. Tyrosine hydroxylase activity in sympathetic nervous system of rats with streptozotocin-induced diabetes. Diabetes 38 (1989) 959-968
36. Semra Y.K., Smith N.C., and Lincoln J. Comparative effects of high glucose on different adult sympathetic neurons in culture. Neuroreport 15 (2004) 2321-2325
37. Sidenius P., and Jakobsen J. Axonal transport in early experimental diabetes. Brain Res. 173 (1979) 315-330
38. Takahara H., Fujimura M., Taniguchi S., Hayashi N., Nakamurs T., and Fujimiya M. Changes in serotonin levels and 5-HT receptor activity in duodenum of streptozotocin-diabetic rats. Am. J. Physiol. Gastrointest. Liver Physiol. 281 (2001) G798-G808
39. Thompson R.J., Doran J.F., Jackson P., Dhillon A.P., and Rode J. PGP 9.5: a new marker for vertebrate neurons and neuroendocrine cells. Brain Res. 278 (1983) 224-228
40. Vinik A.I., Erbas T., Stansberry K.B., and Pittenger G.L. Small fiber neuropathy and neurovascular disturbances in diabetes mellitus. Exp. Clin. Endocrinol. Diabetes 109 Suppl. 2 (2001) S451-S473
41. West M.J., Solmianka L., and Gundersen H.J.G. Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator. Anat. Rec. 231 (1991) 482-497
42. Wilkinson K.D., Lee K.M., Deshpande S., Duerksen-Hughes P., Boss J.M., and Pohl J. The neuron-specific protein PGP 9.5 is an ubiquitin carboxyl-terminal hydrolase. Science 246 (1989) 670-673