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Volumn 262, Issue 2, 2008, Pages 164-172

Liposomal formulation of 5-fluorocytosine in suicide gene therapy with cytosine deaminase - for colorectal cancer

Author keywords

E. coli cytosine deaminase; Gene directed enzyme prodrug therapy; Liposomes

Indexed keywords

AMPHOTERICIN B LIPID COMPLEX; CHOLESTEROL; CYTOSINE DEAMINASE; DIPALMITOYLPHOSPHATIDYLCHOLINE; DOXORUBICIN; FLUCYTOSINE; LIPOSOME; PRODRUG; VIRUS VECTOR;

EID: 40649104944     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2007.12.006     Document Type: Article
Times cited : (18)

References (30)
  • 3
    • 0035181464 scopus 로고    scopus 로고
    • Strategies for enzyme/prodrug cancer therapy
    • Xu G., and McLeod H.L. Strategies for enzyme/prodrug cancer therapy. Clin. Cancer Res. 7 (2001) 3314-3324
    • (2001) Clin. Cancer Res. , vol.7 , pp. 3314-3324
    • Xu, G.1    McLeod, H.L.2
  • 4
    • 0028108469 scopus 로고
    • Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase
    • Huber B.E., Austin E.A., Richards C.A., Davis S.T., and Good S.S. Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase. Proc. Natl. Acad. Sci. USA 91 (1994) 8302-8306
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8302-8306
    • Huber, B.E.1    Austin, E.A.2    Richards, C.A.3    Davis, S.T.4    Good, S.S.5
  • 5
    • 0028297316 scopus 로고
    • Tumors expressing the cytosine deaminase suicide gene can be eliminated in vivo with 5-fluorocytosine and induce protective immunity to wild-type tumor
    • Mullen C.A., Coale M.M., Lowe R., and Blease R.M. Tumors expressing the cytosine deaminase suicide gene can be eliminated in vivo with 5-fluorocytosine and induce protective immunity to wild-type tumor. Cancer Res. 54 (1994) 1503-1506
    • (1994) Cancer Res. , vol.54 , pp. 1503-1506
    • Mullen, C.A.1    Coale, M.M.2    Lowe, R.3    Blease, R.M.4
  • 6
    • 0030767678 scopus 로고    scopus 로고
    • In vivo selective gene expression and therapy mediated by adenoviral vectors for human carcinoembryonic antigen-producing gastric carcinoma
    • Lan K.-H., Kanai F., Shiratori Y., Ohashi M., Tanaka T., Okudaira T., Yoshida Y., Hamada H., and Omata M. In vivo selective gene expression and therapy mediated by adenoviral vectors for human carcinoembryonic antigen-producing gastric carcinoma. Cancer Res. 57 (1997) 4279-4284
    • (1997) Cancer Res. , vol.57 , pp. 4279-4284
    • Lan, K.-H.1    Kanai, F.2    Shiratori, Y.3    Ohashi, M.4    Tanaka, T.5    Okudaira, T.6    Yoshida, Y.7    Hamada, H.8    Omata, M.9
  • 7
    • 0035881303 scopus 로고    scopus 로고
    • Carcinoembryonic antigen-specific suicide gene therapy of cytosine deaminase/5-fluorocytosine enhanced by the Cre/loxP system in the orthotopic gastric carcinoma model
    • Ueda K., Iwahashi M., Nakamori M., Nakamura M., Matsuura I., Yamaue H., and Tanimura H. Carcinoembryonic antigen-specific suicide gene therapy of cytosine deaminase/5-fluorocytosine enhanced by the Cre/loxP system in the orthotopic gastric carcinoma model. Cancer Res. 61 (2001) 6158-6162
    • (2001) Cancer Res. , vol.61 , pp. 6158-6162
    • Ueda, K.1    Iwahashi, M.2    Nakamori, M.3    Nakamura, M.4    Matsuura, I.5    Yamaue, H.6    Tanimura, H.7
  • 8
    • 6544264326 scopus 로고    scopus 로고
    • Effective and safe gene therapy for colorectal carcinoma using the cytosine deaminase gene directed by the carcinoembryonic antigen promoter
    • Cao G., Kuriyama S., Gao J., Kikukawa M., Cui L., Nakatani T., Zhang X., Tsujinoue H., Pan X., Fukui H., and Qi Z. Effective and safe gene therapy for colorectal carcinoma using the cytosine deaminase gene directed by the carcinoembryonic antigen promoter. Gene Ther. 6 (1999) 83-90
    • (1999) Gene Ther. , vol.6 , pp. 83-90
    • Cao, G.1    Kuriyama, S.2    Gao, J.3    Kikukawa, M.4    Cui, L.5    Nakatani, T.6    Zhang, X.7    Tsujinoue, H.8    Pan, X.9    Fukui, H.10    Qi, Z.11
  • 9
    • 0038011874 scopus 로고    scopus 로고
    • Emerging role of liposomal drug carrier systems in cancer chemotherapy
    • Gabizon A. Emerging role of liposomal drug carrier systems in cancer chemotherapy. Liposome Res. 13 (2003) 17-20
    • (2003) Liposome Res. , vol.13 , pp. 17-20
    • Gabizon, A.1
  • 10
    • 0036907725 scopus 로고    scopus 로고
    • Liposomally targeted cytotoxic drugs for the treatment of cancer
    • Harrington K.J., Syrigos K.N., and Vile R.G. Liposomally targeted cytotoxic drugs for the treatment of cancer. J. Pharm. Pharmacol. 54 (2002) 1573-1600
    • (2002) J. Pharm. Pharmacol. , vol.54 , pp. 1573-1600
    • Harrington, K.J.1    Syrigos, K.N.2    Vile, R.G.3
  • 11
    • 0025789143 scopus 로고
    • Pharmacokinetics of stealth versus conventional liposomes: effect of dose
    • Allen T.M., and Hansen C. Pharmacokinetics of stealth versus conventional liposomes: effect of dose. Biochim. Biophys. Acta 1068 (1991) 133-141
    • (1991) Biochim. Biophys. Acta , vol.1068 , pp. 133-141
    • Allen, T.M.1    Hansen, C.2
  • 13
    • 0029150245 scopus 로고
    • Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size
    • Yuan F., Dellian M., Fukumura D., Leuning M., Berk D.A., Torchilin V.P., and Jain R.K. Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size. Cancer Res. 55 (1995) 3752-3756
    • (1995) Cancer Res. , vol.55 , pp. 3752-3756
    • Yuan, F.1    Dellian, M.2    Fukumura, D.3    Leuning, M.4    Berk, D.A.5    Torchilin, V.P.6    Jain, R.K.7
  • 14
    • 0037427945 scopus 로고    scopus 로고
    • The influence of repeated injections on pharmacokinetics and biodistribution of different types of sterically stabilized immunoliposomes
    • Bendas G., Rothe U., Scherphof G.L., and Kamps J.A. The influence of repeated injections on pharmacokinetics and biodistribution of different types of sterically stabilized immunoliposomes. Biochim. Biophys. Acta 1609 (2003) 63-70
    • (2003) Biochim. Biophys. Acta , vol.1609 , pp. 63-70
    • Bendas, G.1    Rothe, U.2    Scherphof, G.L.3    Kamps, J.A.4
  • 15
    • 14144250911 scopus 로고    scopus 로고
    • Recent advances with liposomes as pharmaceutical carriers
    • Torchilin V.P. Recent advances with liposomes as pharmaceutical carriers. Nat. Rev. Drug Discov. 4 (2005) 145-160
    • (2005) Nat. Rev. Drug Discov. , vol.4 , pp. 145-160
    • Torchilin, V.P.1
  • 16
    • 0033802643 scopus 로고    scopus 로고
    • Pegylated liposomal doxorubicin (doxil): reduced clinical cardiotoxicity in patients reaching or exceeding cumulative doses of 500 mg/ml
    • Safra T., Muggia F., Jeffers S., Tsao-Wei D.D., Groshen S., Lyass O., Henderson R., Berry G., and Gabizon A. Pegylated liposomal doxorubicin (doxil): reduced clinical cardiotoxicity in patients reaching or exceeding cumulative doses of 500 mg/ml. Ann. Oncol. 11 (2000) 1029-1033
    • (2000) Ann. Oncol. , vol.11 , pp. 1029-1033
    • Safra, T.1    Muggia, F.2    Jeffers, S.3    Tsao-Wei, D.D.4    Groshen, S.5    Lyass, O.6    Henderson, R.7    Berry, G.8    Gabizon, A.9
  • 17
    • 0036177170 scopus 로고    scopus 로고
    • Liposomal amphotericin B versus conventional amphotericin B in the empirical treatment of persistently febrile neutropenic patients
    • Cagnoni P.J. Liposomal amphotericin B versus conventional amphotericin B in the empirical treatment of persistently febrile neutropenic patients. J. Antimicrob. Chemother. 49 (2002) 81-86
    • (2002) J. Antimicrob. Chemother. , vol.49 , pp. 81-86
    • Cagnoni, P.J.1
  • 21
    • 0034823252 scopus 로고    scopus 로고
    • Transcriptional regulation in cancer gene therapy
    • Haviv Y.S., and Blackwell J. Transcriptional regulation in cancer gene therapy. Isr. Med. Assoc. J. 3 (2001) 517-522
    • (2001) Isr. Med. Assoc. J. , vol.3 , pp. 517-522
    • Haviv, Y.S.1    Blackwell, J.2
  • 22
    • 0033214971 scopus 로고    scopus 로고
    • Application of the Cre recombinase/loxP system further enhances antitumor effects in cell type-specific gene therapy against carcinoembryonic antigen-producing cancer
    • Kijima T., Osaki T., Nishino K., Kumagai T., Funakoshi T., Goto H., Tachibana I., Tanio Y., and Kishimoto T. Application of the Cre recombinase/loxP system further enhances antitumor effects in cell type-specific gene therapy against carcinoembryonic antigen-producing cancer. Cancer Res. 59 (1999) 4906-4911
    • (1999) Cancer Res. , vol.59 , pp. 4906-4911
    • Kijima, T.1    Osaki, T.2    Nishino, K.3    Kumagai, T.4    Funakoshi, T.5    Goto, H.6    Tachibana, I.7    Tanio, Y.8    Kishimoto, T.9
  • 23
    • 0033869563 scopus 로고    scopus 로고
    • Flucytosine: a review of its pharmacology, clinical indications, pharmacokinetics, toxicity and drug interactions
    • Vermes A., Guchelaar H.J., and Dankert J. Flucytosine: a review of its pharmacology, clinical indications, pharmacokinetics, toxicity and drug interactions. J. Antimicrob. Chemother. 46 (2000) 171-179
    • (2000) J. Antimicrob. Chemother. , vol.46 , pp. 171-179
    • Vermes, A.1    Guchelaar, H.J.2    Dankert, J.3
  • 25
    • 34547665645 scopus 로고    scopus 로고
    • High loading dose AmBisome is efficacious and well tolerated in the management of invasive fungal infection in hematology patients
    • McLintock L.A., Cook G., Holyoake T.L., Jones B.L., Kinsey S.E., and Jackson G.H. High loading dose AmBisome is efficacious and well tolerated in the management of invasive fungal infection in hematology patients. Haematologica 92 (2007) 572-573
    • (2007) Haematologica , vol.92 , pp. 572-573
    • McLintock, L.A.1    Cook, G.2    Holyoake, T.L.3    Jones, B.L.4    Kinsey, S.E.5    Jackson, G.H.6
  • 26
    • 34250891378 scopus 로고    scopus 로고
    • Reduced hepatic toxicity, enhanced cellular uptake and altered pharmacokinetics of stavudine loaded galactosylated liposomes
    • Garg M., Dutta T., and Jain N.K. Reduced hepatic toxicity, enhanced cellular uptake and altered pharmacokinetics of stavudine loaded galactosylated liposomes. Eur. J. Pharm. Biopharm. 67 (2007) 76-85
    • (2007) Eur. J. Pharm. Biopharm. , vol.67 , pp. 76-85
    • Garg, M.1    Dutta, T.2    Jain, N.K.3
  • 27
    • 36049008819 scopus 로고    scopus 로고
    • R. Suzuki, T. Takizawa, Y. Kuwata, M. Mutoh, N. Ishiguro, N. Utoguchi, A. Shinohara, M. Eriguchi, H. Yanagie, K. Maruyama, Effective anti-tumor activity of oxaliplatin encapsulated in transferrin-PEG-liposome, Int. J. Pharm., doi:10.1016/j.ijpharm.2007.06.010.
    • R. Suzuki, T. Takizawa, Y. Kuwata, M. Mutoh, N. Ishiguro, N. Utoguchi, A. Shinohara, M. Eriguchi, H. Yanagie, K. Maruyama, Effective anti-tumor activity of oxaliplatin encapsulated in transferrin-PEG-liposome, Int. J. Pharm., doi:10.1016/j.ijpharm.2007.06.010.
  • 28
    • 33644827912 scopus 로고    scopus 로고
    • RGD-based strategies for selective delivery of therapeutics and imaging agents to the tumour vasculature
    • Temming K., Schiffelers R.M., Molema G., and Kok R.J. RGD-based strategies for selective delivery of therapeutics and imaging agents to the tumour vasculature. Drug Resist. Updat. 8 (2005) 381-402
    • (2005) Drug Resist. Updat. , vol.8 , pp. 381-402
    • Temming, K.1    Schiffelers, R.M.2    Molema, G.3    Kok, R.J.4
  • 29
    • 0026459493 scopus 로고
    • Angiogenesis, microvascular architecture, microhemodynamics, and interstitial fluid pressure during early growth of human adenocarcinoma LS174T in SCID mice
    • Leunig M., Yuan F., Menger M.D., Boucher Y., and Goetz A.E. Angiogenesis, microvascular architecture, microhemodynamics, and interstitial fluid pressure during early growth of human adenocarcinoma LS174T in SCID mice. Cancer Res. 52 (1992) 6553-6560
    • (1992) Cancer Res. , vol.52 , pp. 6553-6560
    • Leunig, M.1    Yuan, F.2    Menger, M.D.3    Boucher, Y.4    Goetz, A.E.5


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