Cytokines and pregnancy in rheumatic disease

Annals of the New York Academy of Sciences

Volumn 1069, Issue , 2006, Pages 353-363

  Østensen, Monika ^a   Förger, Frauke ^a   Villiger, Peter M ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

Cytokines; Hormones; Pregnancy; Rheumatic disease; Th2 immune response

Indexed keywords

CYTOKINE; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; TUMOR NECROSIS FACTOR RECEPTOR;

ANKYLOSING SPONDYLITIS; AUTOIMMUNE DISEASE; CELL FUNCTION; CELLULAR DISTRIBUTION; CONFERENCE PAPER; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; FEMALE; HUMAN; IMMUNE RESPONSE; NEUROENDOCRINE SYSTEM; PREGNANCY; PREGNANCY DISORDER; RHEUMATIC DISEASE; RHEUMATOID ARTHRITIS; SYSTEMIC LUPUS ERYTHEMATOSUS; TH1 CELL; TH2 CELL;

EID: 33745634096     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1351.033     Document Type: Conference Paper

References (43)

1. WEGMANN, T.G., H. LIN, L. GUILBERT & T.R. MOSMANN. 1993. Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a Th2 phenomenon? Immunol. Today 14: 353-356.
2. CHAOUAT, G., E. MENU, D.A. CLARK, et al. 1990. Control of fetal survival in CBA x DBA/2 mice by lymphokine therapy. J. Reprod. Fertil. 89: 447-458.
3. CHAOUAT, G., N. LEDÉE-BATAILLE, S. DUBANCHET, et al. 2004. Th1/Th2 paradigm in pregnancy: paradigm lost? Int. Arch. Allergy Immunol. 139: 93-119.
4. ASHKAR, A.A., J.P. Di SANTO & B.A. CROY. 2000. Interferon gamma contributes to initiation of uterine vascular modification, decidual integrity, and uterine natural killer cell maturation during normal murine pregnancy. J. exp. Med. 192: 259-270.
5. FUKUSHIMA, K., S. MIYAMOTO, K. TSUKIMORI, et al. 2005. Tumor necrosis factor and vascular endothelial growth factor induce endothelial integrin repertories, regulating endovascular differentiation and apoptosis in a human extravillous trophoblast cell line. Biol. Reprod. 73: 172-179.
6. OPSJON, S.L., N.C. WATHEN, S. TINGULSTAD, et al. 1993. Tumor necrosis factor, interleukin 1, and interleukin-6 in normal human pregnancy. Am. J. Obstet. Gynecol. 69: 397-404.
7. HEBISCH, G., P.M. NEUMAIER-WAGNER, R. HUCH & U. VON MANDACH. 2004. Maternal serum interleukin-1 beta, -6 & -8 levels and potential determinants in pregnancy and peripartum. J. Perinat. Med. 32: 475-480.
8. VEITH, G.L. & G.E. RICE. 1999. Interferon gamma expression during human preg-nancy and in association of labour. Gynecol. Obstet. Invest. 48: 163-167.
9. RUSSWURM, G.P., A.M. MACKLER, O.R. FAGOAGA, et al. 1997. Soluble human leukocyte antigens, interleukin-6, and interferon-gamma during pregnancy. Am. J. Reprod. Immunol. 38: 256-262.
10. MAKHSEED, M., R. RAGHUPATHY, F. Azizieh, et al. 2000. Circulating cytokines and CD30 in normal human pregnancy and recurrent spontaneous abortions. Hum. Reprod. 15: 2011-2017.
11. ELLIS, J., U.B. WENNERHOLM, A. BENGTSSON, et al. 2001. Levels of dimethylarginines and cytokines in mild and severe preeclampsia. Acta. Obstet. Gynecol. Scand. 80: 602-608.
12. AUSTGULEN, R., E. LIEN, N.B. LIABAKK, et al. 1994. Increased levels of cytokines and cytokine activity modifiers in normal pregnancy. Eur. J. Obstet. Gynecol. Reprod. Biol. 57: 149-155.
13. KUPFERMINC, M.J., A.M. PEACEMAN, D. ADERKA, et al. 1995. Soluble tumor necrosis factor receptors in maternal plasma and second-trimester amniotic fluid. Am. J. Obstet. Gynecol. 173: 900-905.
14. KUPFERMINC, M.J., A.M. PEACEMAN, D. ADERKA, et al. 1996. Soluble tumor necrosis factor receptors and interleukin-6 levels in patients with severe preeclampsia. Obstet. Gynecol. 88: 420-427.
15. BAHAR, A.M., H.W. GHALIB, R.A. MOOSA, et al. 2003. Maternal serum interleukin-6, interleukin-8, tumor necrosis factor-α and interferon-γ in preterm labor. Acta. Obstet. Gynecol. Scand. 82: 543-549.
16. FASOULIOTIS, S.J., S.D. SPANDORFER, S.S. WITTKIN, et al. 2004. Maternal serum levels of interferon-gamma and interleukin-2 soluble receptor-alpha predict the outcome of early IVF pregnancies. Hum. Reprod. 19: 1357-1363.
17. LIN, H., T.R. MOSMANN, L. GUILBERT, et al. 1993. Synthesis of T helper 2-type cytokines at the maternal-fetal interface. J. Immunol. 151: 4562-4572.
18. CADET, P., P.L. RADY, S.K. TRYING, et al. 1995. Interleukin messenger ribonucleic acid in human placenta: implications of a role for interleukin-10 in fetal allograft protection. Am. J. Obstet. Gynecol. 173: 25-29.
19. BENNETT, W.A., S. LAGOO-DEENADAYLAN, N.S. WHITWORTH, et al. 1999. First trimester human chorionic villi express both immunoregulatory and inflammatory cytokines: a role for interleukin 10 in regulating the cytokine network of pregnancy. Am. J. Reprod. Immunol. 41: 70-78.
20. RUSSELL, A.S., C. JOHNSTON, C. CHEW & W.P. MAKSYMOWYCH. 1997. Evidence for reduced Th1 function in normal pregnancy: a hypothesis for the remission of rheumatroid arthritis. J. Rheumatol. 24: 1045-1050.
21. EKERFELT, C., L. MATTHIESEN, G. BERG & J. ERNERUDH 1997. Paternal leukocytes selectively increase secretion of IL-4 in peripheral blood during normal pregnancies: demonstrated by a novel one-way MLC measuring cytokine secretion. Am. J. Reprod. Immunol. 38: 320-326.
22. EKERFELT, C., L. MATTHIESEN, G. BERG & J. ERNERUDH. 1998. Increased numbers of circulating interferon-gamma- and interleukin-4-secreting cells during normal pregnancy. Am. J. Reprod. Immunol. 39: 362-367.
23. TRANCHOT-DIALLO, J., G. GRAS, F. PARNET-MATHIEU, et al. 1997. Modulations of cytokine expression in pregnant women. Am. J. Reprod. Immunol. 37: 215-226.
24. PICCINI, M.P., C. SCALETTI, E. MAGGI & S. ROMAGNANI. 2000. Role of hormone-controlled Th1- and Th2-type cytokines in successful pregnancy. J. Neuroimmunol. 109: 30-33.
25. TAGAWA, N., Y. HIDAKA, T. TAKANO, et al. 2004. Serum concentrations of androstenediol and androstenediol sulfate, and their relation to cytokine production during and after normal pregnancy. Steroids 69: 675-680.
26. TAGAWA, N., Y. HIDAKA, T. TAKANO, et al. 2004. Serum concentrations of dehydroepiandrosterone and dehydroepiandrosterone sulfate and their relation to cytokine production during and after normal pregnancy. Clin. Chim. Acta. 340: 187-193.
27. ELENKOV, I.J., R.L. WILDER, V.K. BAKALOV, et al. 2001. IL-12, TNF-alpha, and hormonal changes during late pregnancy and early postpartum: implications for autoimmune disease activity during these times. J. Clin. Endocrinol. Metab. 86: 4933-4938.
28. ELENKOV, I.J., D.A. PAPANICOLAOU, R.L. WILDER & G.P. CHROUSOS. 1996. Modulatory effects of glucocorticoids and catecholamines on human interleukin-12 and interleukin-10 production: clinical implications. Proc. Assoc. Am. Physicians 108: 374-381.
29. SZEKERES-BARTHO, J., Z. FAUST & P. VARGA. 1995. The expression of a progesterone-induced immunomodulatory protein in pregnancy lymphocytes. Am. J. Reprod. Immunol. 34: 342-348.
30. SZEREDAY, L., P. VARGA & J. SZEKERES-BARTHO. 1997. Cytokine production by lymphocytes in pregnancy. Am. J. Reprod. Immunol. 38: 418-422.
31. PICCINI, M.P., M.G. GIUDIZI, R. BIAGIOTTI, et al. 1995. Progesterone favors the development of human T helper cells producing Th2-type cytokines and promotes both IL-4 production and membrane CD30 expression in established Th1 cell clones. J. Immunol. 155: 128-133.
32. CORREALE, J., M. ARIAS & W. GILMORE. 1998. Steroid hormone regulation of cytokine secretion by proteolipid protein-specific CD4+ T cell clones isolated from multiple sclerosis patients and normal control subjects. J. Immunol. 161: 3365-3374.
33. ØSTENSEN, M., L. FUHRER, R. MATHIEU, et al. 2004. A prospective study of pregnant patients with rheumatoid arthritis and ankylosing spondylitis using validated clinical instruments. Ann. Rheum. Dis. 63: 1212-1217.
34. GRAN, J.T. & M. ØSTENSEN. 1998. Spondylarthritides in females. Ballieres Clin. Rheumatol. 12: 695-715.
35. VAN ROON, J.A.G. & J.W.J. BIJLSMA. 2002. Th2 mediated regulation in RA and the spondylarthropathies. Ann. Rheum. Dis. 61: 951-954.
36. ØSTENSEN, M., F. FÖRGER, J. LEE NELSON, et al. 2005. Pregnancy in patients with rheumatic disease: anti-inflammatory cytokines increase in pregnancy and decrease post partum. Ann. Rheum. Dis. 64: 839-844.
37. WAIS, T., W. FIERZ, T. STOLL & P.M. VILLIGER. 2003. Subclinical disease activity in systemic lupus erythematosus: immunoinflammatory markers do not normalize in clinical remission. J. Rheumatol. 30: 2133-2139.
38. GERLI, R., C. LUNARDI, F. VINANTE, et al. 2001. Role of CD30+ T cells in rheumatoid arthritis: a counter-regulatory paradigm for Th1-driven diseases. Trends Immunol. 2: 72-77.
39. VANNIER, E., L.C. MILLER & C.A. DINARELLO. 1992. Coordinated antiinflammatory effects of interleukin-4: interleukin 4 suppresses interleukin 1 production but up-regulates gene expression and synthesis of interleukin 1 receptor antagonist. Proc. Natl. Acad. Sci. USA 89: 4076-4080.
40. JOYCE, D.A. & J.H. STEER. 1996. IL-4, IL-10 and IFN-γ have distinct, but interacting, effects of differentiation-induced changes in TNF-a and receptor release by cultured human monocytes. Cytokine 8: 49-57.
41. DORIA, A., A. GHIRADELLO, L. IACCARINO, et al. 2004. Pregnancy, cytokines, and disease activity in systemic lupus erythematosus. Arthritis Rheum. 51: 989-995.
42. MUNOZ-VALLE, J.F., M.M. VAZQUEZ-DEL, T. GARCIA-IGLESIAS, et al. 2003. T(H)1/T(H)2 cytokine profile, metalloprotease-9 activity and hormonal status in pregnant rheumatoid arthritis and systemic lupus erythematosus patients. Clin. Exp. Immunol. 131: 377-384.
43. ELENKOV, I.J. 1997. Does differential neuroendocrine control of cytokine production govern the expression of autoimmune diseases in pregnancy and the postpartum period? Mol. Med. Today 3: 379-383.