Non-classical processes in surface hemostasis: Mechanisms for the poly-N-acetyl glucosamine-induced alteration of red blood cell morphology and surface prothrombogenicity

Biomedical Materials

Volumn 3, Issue 1, 2008, Pages

  Fischer, Thomas H ^a   Valeri, C Robert ^b   Smith, Carr J ^a   Scull, Christopher M ^a   Merricks, Elizabeth P ^a   Nichols, Timothy C ^a   Demcheva, Marina ^c   Vournakis, John N ^c  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b Nav Blood Res Lab   (United States)

^c Marine Polymer Technologies Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

N ACETYLGLUCOSAMINE; NANOFIBER; PHOSPHATIDYLSERINE; THROMBIN; HEMOSTATIC AGENT; POLY N ACETYL GLUCOSAMINE; POLY-N-ACETYL GLUCOSAMINE;

ARTICLE; BLOOD CLOTTING; CELL ACTIVATION; CELL INTERACTION; CELL ISOLATION; CELL STRUCTURE; CONTROLLED STUDY; DIATOM; ECHINOCYTE; ELECTRON MICROSCOPY; ELECTROPHORESIS; ERYTHROCYTE; HEMOSTASIS; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; SURFACE PROPERTY; THROMBOCYTE; THROMBOGENICITY; WESTERN BLOTTING; CELL ADHESION; CELL CULTURE; CHEMISTRY; CYTOLOGY; DRUG EFFECT; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; THROMBOSIS;

NITZSCHIA ALBA;

ACETYLGLUCOSAMINE; CELL ADHESION; CELLS, CULTURED; ERYTHROCYTES; HEMOSTASIS; HEMOSTATICS; HUMANS; SURFACE PROPERTIES; THROMBOSIS;

EID: 40549093613     PISSN: 17486041     EISSN: 1748605X     Source Type: Journal    
DOI: 10.1088/1748-6041/3/1/015009     Document Type: Article

References (49)

1. Valeri C R, Crowley J P and Loscalzo J 1998 The red cell transfusion trigger: has a sin of commission now become a sin of omission? Transfusion 38 602-10
2. Valeri C R, Ellis A, Donahue K, Curran T and Pivacek L 1985 The viability of young and old baboon red cells stored in the liquid state at 4 C Prog. Clin. Biol. Res. 195 429-41
3. Gerrard J M, Docherty J C, Israels S J, Cheang M S, Bishop A J, Kobrinsky N L, Schroeder M L and Israels E D 1989 A reassessment of the bleeding time: association of age, hematocrit, platelet function, von Willebrand factor, and bleeding time thromboxane B2 with the length of the bleeding time Clin. Invest. Med. 12 165-71
4. Casati S, Passerini P, Campise M R, Graziani G, Cesana B, Perisic M and Ponticelli C 1987 Benefits and risks of protracted treatment with human recombinant erythropoietin in patients having haemodialysis Br. Med. J. (Clin. Res. Ed.) 295 1017-20
5. Tangelder G J, Teirlinck H C, Slaaf D W and Reneman R S 1985 Distribution of blood platelets flowing in arterioles Am. J. Physiol. 248 H318-23
6. Turitto V and Weiss H 1980 Red blood cells: their dual role in thrombosis formation Science 207 541-3
7. Peyrou V, Lormeau J C, Herault J P, Gaich C, Pfliegger A M and Herbert J M 1999 Contribution of erythrocytes to thrombin generation in whole blood Thromb. Haemost. 81 400-6
8. Saniabadi A R, Lowe G D, Madhok R, Spowart K, Shaw B, Barbenel J C and Forbes C D 1987 Red blood cells mediate spontaneous aggregation of platelets in whole blood Atherosclerosis 66 175-80
9. Santos M T, Valles J, Marcus A J, Safier L B, Broekman M J, Islam N, Ullman H L, Eiroa A M and Aznar J 1991 Enhancement of platelet reactivity and modulation of eicosanoid production by intact erythrocytes. A new approach to platelet activation and recruitment J. Clin. Invest. 87 571-80
10. Luthje J 1989 Extracellular adenine compounds, red blood cells and haemostasis: facts and hypotheses Blut 59 367-74
11. Iuliano L, Violi F, Pedersen J Z, Pratico D, Rotilio G and Balsano F 1992 Free radical-mediated platelet activation by hemoglobin released from red blood cells Arch. Biochem. Biophys. 299 220-4
12. Gladwin M T, Crawford J H and Patel R P 2004 The biochemistry of nitric oxide, nitrite, and hemoglobin: role in blood flow regulation Free Radical Biol. Med. 36 707-17
13. Valles J, Santos M T, Aznar J, Marcus A J, Martinez-Sales V, Portoles M, Broekman M J and Safier L B 1991 Erythrocytes metabolically enhance collagen-induced platelet responsiveness via increased thromboxane production, adenosine diphosphate release, and recruitment Blood 78 154-62
14. Bonomini M, Sirolli V, Merciaro G, Antidormi T, Di Liberato L, Brummer U, Papponetti M, Cappelli P, Di Gregorio P and Arduini A 2005 Red blood cells may contribute to hypercoagulability in uraemia via enhanced surface exposure of phosphatidylserine Nephrol. Dial. Transplant. 20 361-6
15. Setty B N, Rao A K and Stuart M J 2001 Thrombophilia in sickle cell disease: the red cell connection Blood 98 3228-33
16. Helley D, Eldor A, Girot R, Ducrocq R, Guillin M C and Bezeaud A 1996 Increased procoagulant activity of red blood cells from patients with homozygous sickle cell disease and beta-thalassemia Thromb. Haemost. 76 322-7
17. Zwaal R F and Schroit A J 1997 Pathophysiologic implications of membrane phospholipid asymmetry in blood cells Blood 89 1121-32
18. Vournakis J N, Demcheva M, Whitson A, Guirca R and Pariser E R 2004 Isolation, purification, and characterization of poly-N-acetyl glucosamine use as a hemostatic agent J. Trauma 57 S2-6
19. Fischer T H, Bode A P, Demcheva M and Vournakis J N 2007 Hemostatic properties of glucosamine-based materials J. Biomed. Mater. Res. A 80 167-74
20. Fischer T H, Connolly R, Thatte H S and Schwaitzberg S S 2004 Comparison of structural and hemostatic properties of the poly-N-acetyl glucosamine Syvek Patch with products containing chitosan Microsc. Res. Tech. 63 168-74
21. Fischer T H, Thatte H S, Nichols T C, Bender-Neal D E, Bellinger A D and Vournakis J N 2005 Synergistic platelet integrin signaling and factor XII activation in poly-N-acetyl glucosamine fiber-mediated hemostasis Biomaterials 26 5433-43
22. Valeri C R, Srey R, Tilahun D and Ragno G 2004 In vitro effects of poly-N-acetyl glucosamine on the activation of platelets in platelet-rich plasma with and without red blood cells J. Trauma 57 S22-5 discussion S25
23. Vroman L 1964 Effects of hydrophobic surfaces upon blood coagulation Thromb. Diath. Haemorrh. 10 455-93
24. Vroman L and Adams A L 1967 Possible involvement of fibrinogen and proteolysis in surface activation. A study with the recording ellipsometer Thromb. Diath. Haemorrh. 18 510-24
25. Cole D J et al 1999 A pilot study evaluating the efficacy of a fully acetylated poly-N-acetyl glucosamine membrane formulation as a topical hemostatic agent Surgery 126 510-7
26. Vournakis J N, Demcheva M, Whitson A B, Finkielsztein S and Connolly R J 2003 The RDH bandage: hemostasis and survival in a lethal aortotomy hemorrhage model J. Surg. Res. 113 1-5
27. Nader R G, Garcia J C, Drushal K and Pesek T 2002 Clinical evaluation of SyvekPatch in patients undergoing interventional, EPS and diagnostic cardiac catheterization procedures J. Invasive Cardiol. 14 305-7
28. Fischer T H, Robbins M E, Bode A P, Nichols T C, Bellinger D E and Schoenfisch M H 2004 Evidence that rehydrated, lyophilized red blood cells are sufficiently deformable for normal microcirculation transit Microsc. Res. Tech. 65 62-71
29. Sanders W E, Read M S, Reddick R L, Garris J B and Brinkhous K M 1988 Thrombotic thrombocytopenia with von Willebrand factor deficiency induced by botrocetin. An animal model Lab. Invest. 59 443-52
30. Laemmli U K 1970 Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 680-5
31. Khodadad J K and Weinstein R S 1983 The band 3-rich membrane of llama erythrocytes: studies on cell shape and the organization of membrane proteins J. Membr. Biol. 72 161-71
32. Hoefner D M, Blank M E, Davis B M and Diedrich D F 1994 Band 3 antagonists, p-azidobenzylphlorizin and DIDS, mediate erythrocyte shape and flexibility changes as characterized by digital image morphometry and microfiltration J. Membr. Biol. 141 91-100
33. Tachev K D, Danov K D and Kralchevsky P A 2004 On the mechanism of stomatocyte-echinocyte transformations of red blood cells: experiment and theoretical model Colloids Surf. B Biointerfaces 34 123-40
34. Wong P 1999 A basis of echinocytosis and stomatocytosis in the disc-sphere transformations of the erythrocyte J. Theor. Biol. 196 343-61
35. Mohandas N, Winardi R, Knowles D, Leung A, Parra M, George E, Conboy J and Chasis J 1992 Molecular basis for membrane rigidity of hereditary ovalocytosis. A novel mechanism involving the cytoplasmic domain of band 3 J. Clin. Invest. 89 686-92
36. Mohandas N and Chasis J A 1993 Red blood cell deformability, membrane material properties and shape: regulation by transmembrane, skeletal and cytosolic proteins and lipids Semin. Hematol. 30 171-92
37. Yasin Z, Witting S, Palascak M B, Joiner C H, Rucknagel D L and Franco R S 2003 Phosphatidylserine externalization in sickle red blood cells: associations with cell age, density, and hemoglobin F Blood 102 365-70
38. Reardon D M, Seymour C A, Cox T M, Pinder J C, Schofield A E and Tanner M J 1993 Hereditary ovalocytosis with compensated haemolysis Br. J. Haematol. 85 197-9
39. Dhermy D, Garbarz M, Lecomte M C, Feo C, Bournier O, Chaveroche I, Gautero H, Galand C and Boivin P 1986 Hereditary elliptocytosis: clinical, morphological and biochemical studies of 38 cases Nouv. Rev. Fr. Hematol. 28 129-40
40. Ratnoff O D and Rosenblum J M 1958 Role of Hageman factor in the initiation of clotting by glass; evidence that glass frees Hageman factor from inhibition Am. J. Med. 25 160-8
41. Vroman L, Adams A L, Fischer G C and Munoz P C 1980 Interaction of high molecular weight kininogen, factor XII, and fibrinogen in plasma at interfaces Blood 55 156-9
42. Scarborough D E, Mason R G, Dalldorf F G and Brinkhous K M 1969 Morphologic manifestations of blood-solid interfacial reactions. A scanning and transmission electron microscopic study Lab. Invest. 20 164-9
43. Barr H 1941 The stickiness of platelets Lancet 238 609-10
44. Banerjee T and Kuypers F A 2004 Reactive oxygen species and phosphatidylserine externalization in murine sickle red cells Br. J. Haematol. 124 391-402
45. Zhou Q, Zhao J, Stout J G, Luhm R A, Wiedmer T and Sims P J 1997 Molecular cloning of human plasma membrane phospholipid scramblase. A protein mediating transbilayer movement of plasma membrane phospholipids J. Biol. Chem. 272 18240-4
46. Andrews D A, Yang L and Low P S 2002 Phorbol ester stimulates a protein kinase C-mediated agatoxin-TK- sensitive calcium permeability pathway in human red blood cells Blood 100 3392-9
47. Connolly R J 2004 Application of the poly-N-acetyl glucosamine-derived rapid deployment hemostat trauma dressing in severe/lethal Swine hemorrhage trauma models J. Trauma 57 S26-8
48. King D R, Cohn S M and Proctor K G 2004 Modified rapid deployment hemostat bandage terminates bleeding in coagulopathic patients with severe visceral injuries J. Trauma 57 756-9
49. Najjar S F, Healey N A, Healey C M, McGarry T, Khan B, Thatte H S and Khuri S F 2004 Evaluation of poly-N-acetyl glucosamine as a hemostatic agent in patients undergoing cardiac catheterization: a double-blind, randomized study J. Trauma 57 S38-41