메뉴 건너뛰기




Volumn 22, Issue 3, 2008, Pages 662-670

The role of acetaldehyde in mediating effects of alcohol on expression of endogenous opioid system genes in a neuroblastoma cell line

Author keywords

4 methylpyrazole; Ethanol; Gene expression; Opioid peptides receptors

Indexed keywords

4 METHYLPYRAZOLE; ACETALDEHYDE; ALCOHOL; KAPPA OPIATE RECEPTOR; OPIATE RECEPTOR; PRODYNORPHIN; PROENKEPHALIN; PROOPIOMELANOCORTIN;

EID: 40449142848     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.07-8346com     Document Type: Article
Times cited : (20)

References (61)
  • 3
    • 0035111309 scopus 로고    scopus 로고
    • Ethanol consumption and reward are decreased in mu-opiate receptor knockout mice
    • Hall, F. S., Sora, I., and Uhl, G. R. (2001) Ethanol consumption and reward are decreased in mu-opiate receptor knockout mice. Psychopharmacology (Berl.) 154, 43-49
    • (2001) Psychopharmacology (Berl.) , vol.154 , pp. 43-49
    • Hall, F.S.1    Sora, I.2    Uhl, G.R.3
  • 6
    • 10844263548 scopus 로고    scopus 로고
    • A polymorphism of the mu-opioid receptor gene (OPRM1) and sensitivity to the effects of alcohol in humans
    • Ray, L. A., and Hutchison, K. E. (2004) A polymorphism of the mu-opioid receptor gene (OPRM1) and sensitivity to the effects of alcohol in humans. Alcohol. Clin. Exp. Res. 28, 1789-1795
    • (2004) Alcohol. Clin. Exp. Res , vol.28 , pp. 1789-1795
    • Ray, L.A.1    Hutchison, K.E.2
  • 8
    • 0030007768 scopus 로고    scopus 로고
    • Lipid vs. protein theories of alcohol action in the nervous system
    • Peoples, R. W., Li, C., and Weight, F. F. (1996) Lipid vs. protein theories of alcohol action in the nervous system. Annu. Rev. Pharmacol. Toxicol. 36, 185-201
    • (1996) Annu. Rev. Pharmacol. Toxicol , vol.36 , pp. 185-201
    • Peoples, R.W.1    Li, C.2    Weight, F.F.3
  • 9
    • 0032479880 scopus 로고    scopus 로고
    • Ethanol and neurotransmitter interactions from molecular to integrative effects
    • Faingold, C. L., N'Gouemo, P., and Riaz, A. (1998) Ethanol and neurotransmitter interactions from molecular to integrative effects. Prog. Neurobiol. 55, 509-535
    • (1998) Prog. Neurobiol , vol.55 , pp. 509-535
    • Faingold, C.L.1    N'Gouemo, P.2    Riaz, A.3
  • 11
    • 0036130919 scopus 로고    scopus 로고
    • Ethanol stimulates cAMP-responsive element (CRE)-mediated transcription via CRE-binding protein and cAMP-dependent protein kinase
    • Asher, O., Cunningham, T. D., Yao, L., Gordon, A. S., Diamond, I. (2002) Ethanol stimulates cAMP-responsive element (CRE)-mediated transcription via CRE-binding protein and cAMP-dependent protein kinase. J. Pharmacol. Exp. Ther. 301, 66-70
    • (2002) J. Pharmacol. Exp. Ther , vol.301 , pp. 66-70
    • Asher, O.1    Cunningham, T.D.2    Yao, L.3    Gordon, A.S.4    Diamond, I.5
  • 12
    • 17644391694 scopus 로고    scopus 로고
    • Calcium-stimulated adenylyl cyclases are critical modulators of neuronal ethanol sensitivity
    • Maas, J. W. Jr., Vogt, S. K., Chan, G. C., Pineda, V. V., Storm, D. R., and Muglia, L. J. (2005) Calcium-stimulated adenylyl cyclases are critical modulators of neuronal ethanol sensitivity. J. Neurosci. 25, 4118-4126
    • (2005) J. Neurosci , vol.25 , pp. 4118-4126
    • Maas Jr., J.W.1    Vogt, S.K.2    Chan, G.C.3    Pineda, V.V.4    Storm, D.R.5    Muglia, L.J.6
  • 13
  • 14
    • 0031913690 scopus 로고    scopus 로고
    • Selective increases in phosphoinositide signaling activity and G protein levels in postmortem brain from subjects with schizophrenia or alcohol dependence
    • Jope, R. S., Song, L., Grimes, C. A., Pacheco, M. A., Dilley, G. E., Li, X., Meltzer, H. Y., Overholser, J. C., and Stockmeier, C. A. (1998) Selective increases in phosphoinositide signaling activity and G protein levels in postmortem brain from subjects with schizophrenia or alcohol dependence. J. Neurochem. 70, 763-771
    • (1998) J. Neurochem , vol.70 , pp. 763-771
    • Jope, R.S.1    Song, L.2    Grimes, C.A.3    Pacheco, M.A.4    Dilley, G.E.5    Li, X.6    Meltzer, H.Y.7    Overholser, J.C.8    Stockmeier, C.A.9
  • 15
    • 0030776897 scopus 로고    scopus 로고
    • Basic fibroblast growth factor-and platelet-derived growth factor-mediated cell proliferation in B104 neuroblastoma cells: Effect of ethanol on cell cycle kinetics
    • Luo, J., and Miller, M. W. (1997) Basic fibroblast growth factor-and platelet-derived growth factor-mediated cell proliferation in B104 neuroblastoma cells: effect of ethanol on cell cycle kinetics. Brain Res. 770, 139-150
    • (1997) Brain Res , vol.770 , pp. 139-150
    • Luo, J.1    Miller, M.W.2
  • 17
    • 0033981786 scopus 로고    scopus 로고
    • Characterization of promoter elements mediating ethanol regulation of hsc70 gene transcription
    • Wilke, N., Sganga, M. W., Gayer, G. G., Hsieh, K. P., and Miles, M. F. (2000) Characterization of promoter elements mediating ethanol regulation of hsc70 gene transcription. J. Pharmacol. Exp. Ther. 292, 173-180
    • (2000) J. Pharmacol. Exp. Ther , vol.292 , pp. 173-180
    • Wilke, N.1    Sganga, M.W.2    Gayer, G.G.3    Hsieh, K.P.4    Miles, M.F.5
  • 18
    • 0032437719 scopus 로고    scopus 로고
    • Prenatal ethanol exposure selectively reduces the mRNA encoding-1 thyroid hormone receptor in fetal rat brain
    • Scott, H., Sun, G., and Zoeller, R. (1998) Prenatal ethanol exposure selectively reduces the mRNA encoding-1 thyroid hormone receptor in fetal rat brain. Alcohol. Clin. Exp. Res. 22, 2111-2117
    • (1998) Alcohol. Clin. Exp. Res , vol.22 , pp. 2111-2117
    • Scott, H.1    Sun, G.2    Zoeller, R.3
  • 19
    • 0032998102 scopus 로고    scopus 로고
    • Chronic ethanol consumption leads to destabilization of rat liver β-galactoside 2,6-silayltransferase mRNA
    • Rao, M., and Lakshman, M. (1999) Chronic ethanol consumption leads to destabilization of rat liver β-galactoside 2,6-silayltransferase mRNA. Metabolism 48, 797-803
    • (1999) Metabolism , vol.48 , pp. 797-803
    • Rao, M.1    Lakshman, M.2
  • 20
    • 0031759872 scopus 로고    scopus 로고
    • Effects of ethanol on gene expression in rat bone: Transient dose-dependent changes in mRNA levels for matrix proteins, skeletal growth factors and cytokines are followed by reductions in bone formation
    • Turner, R., Wronski, T., Zhang, M., Kidder, L., Bloomfield, S., and Sibonga, J. (1998) Effects of ethanol on gene expression in rat bone: transient dose-dependent changes in mRNA levels for matrix proteins, skeletal growth factors and cytokines are followed by reductions in bone formation. Alcohol. Clin. Exp. Res. 22, 1591-1599
    • (1998) Alcohol. Clin. Exp. Res , vol.22 , pp. 1591-1599
    • Turner, R.1    Wronski, T.2    Zhang, M.3    Kidder, L.4    Bloomfield, S.5    Sibonga, J.6
  • 21
    • 0030727657 scopus 로고    scopus 로고
    • Ethanol down-regulates the transcription of microsomal triglyceride transfer protein gene
    • Lin, M., Li, J., Wang, E., Princler, G., Kauffman, F., and Kung, H. (1997) Ethanol down-regulates the transcription of microsomal triglyceride transfer protein gene. FASEB J. 11, 1145-1152
    • (1997) FASEB J , vol.11 , pp. 1145-1152
    • Lin, M.1    Li, J.2    Wang, E.3    Princler, G.4    Kauffman, F.5    Kung, H.6
  • 22
    • 0029988704 scopus 로고    scopus 로고
    • Ethanol-induced alterations in post-translational processing, but not secretion of luteinizing hormone-releasing hormone in vitro
    • Uddin, S., Wilson, T., Emanuele, M., Williams, D., Kelley, M., and Emanuele, N. (1996) Ethanol-induced alterations in post-translational processing, but not secretion of luteinizing hormone-releasing hormone in vitro. Alcohol. Clin. Exp. Res. 20, 556-560
    • (1996) Alcohol. Clin. Exp. Res , vol.20 , pp. 556-560
    • Uddin, S.1    Wilson, T.2    Emanuele, M.3    Williams, D.4    Kelley, M.5    Emanuele, N.6
  • 23
    • 6044246091 scopus 로고    scopus 로고
    • Acetaldehyde: Deja vu du jour.
    • Deitrich, R. A. (2004) Acetaldehyde: deja vu du jour. J. Stud. Alcohol. 65, 557-572
    • (2004) J. Stud. Alcohol , vol.65 , pp. 557-572
    • Deitrich, R.A.1
  • 24
    • 1342306772 scopus 로고    scopus 로고
    • Is ethanol a pro-drug? The role of acetaldehyde in the central effects of ethanol. 2004
    • Quertemont, E., and Tambour, S. (2004) Is ethanol a pro-drug? The role of acetaldehyde in the central effects of ethanol. 2004 Trends Pharmacol. Sci. 25, 130-134
    • (2004) Trends Pharmacol. Sci , vol.25 , pp. 130-134
    • Quertemont, E.1    Tambour, S.2
  • 27
    • 0028902333 scopus 로고
    • Mechanisms of acetaldehyde-mediated growth inhibition: Delayed cell cycle progression and induction of apoptosis
    • Zimmerman, B. T., Crawford, D. G., Dahl, R., Simon, F., and Mapoles, J. (1995) Mechanisms of acetaldehyde-mediated growth inhibition: delayed cell cycle progression and induction of apoptosis. Alcohol. Clin. Exp. Res. 19, 434-440
    • (1995) Alcohol. Clin. Exp. Res , vol.19 , pp. 434-440
    • Zimmerman, B.T.1    Crawford, D.G.2    Dahl, R.3    Simon, F.4    Mapoles, J.5
  • 28
    • 0029043990 scopus 로고
    • Acetaldehyde: Genotoxicity and cytotoxicity in human lymphocytes
    • Singh, N. P., and Khan, A. (1995) Acetaldehyde: genotoxicity and cytotoxicity in human lymphocytes. Mutat. Res. 337, 9-17
    • (1995) Mutat. Res , vol.337 , pp. 9-17
    • Singh, N.P.1    Khan, A.2
  • 29
    • 0033519876 scopus 로고    scopus 로고
    • Acetaldehyde cytotoxicity in cultured rat astrocytes
    • Holownia, A., Ledig, M., Braszko, J. J., and Menez, J. F. (1999) Acetaldehyde cytotoxicity in cultured rat astrocytes. Brain Res. 833, 202-208
    • (1999) Brain Res , vol.833 , pp. 202-208
    • Holownia, A.1    Ledig, M.2    Braszko, J.J.3    Menez, J.F.4
  • 31
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl, M. W. (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 29, e45
    • (2001) Nucleic Acids Res , vol.29
    • Pfaffl, M.W.1
  • 32
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak, K. J., and Schmittgen, T. D. (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25, 402-408
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 33
    • 0035043217 scopus 로고    scopus 로고
    • Quantification of HER2/neu gene amplification by competitive PCR using fluorescent melting curve analysis
    • Lyon, E., Millson, A., Lowery, M. C., Woods, R., and Wittwer, C. T. (2001) Quantification of HER2/neu gene amplification by competitive PCR using fluorescent melting curve analysis. Clin. Chem. 47, 844-851
    • (2001) Clin. Chem , vol.47 , pp. 844-851
    • Lyon, E.1    Millson, A.2    Lowery, M.C.3    Woods, R.4    Wittwer, C.T.5
  • 34
    • 0037449456 scopus 로고    scopus 로고
    • Ethanol differently affects stress protein and HERG K+ channel expression in SH-SY5Y cells
    • Muhlbauer, E., and Rommelspacher, H. (2003) Ethanol differently affects stress protein and HERG K+ channel expression in SH-SY5Y cells. Eur. J. Pharmacol. 459, 121-129
    • (2003) Eur. J. Pharmacol , vol.459 , pp. 121-129
    • Muhlbauer, E.1    Rommelspacher, H.2
  • 35
    • 0037329682 scopus 로고    scopus 로고
    • Alcoholism: Allostasis and beyond
    • Koob, G. F. (2003) Alcoholism: allostasis and beyond. Alcohol. Clin. Exp. Res. 27, 232-243
    • (2003) Alcohol. Clin. Exp. Res , vol.27 , pp. 232-243
    • Koob, G.F.1
  • 36
    • 2442658861 scopus 로고    scopus 로고
    • Opioids and alcoholism
    • Oswald, L. M., and Wand, G. S. (2004) Opioids and alcoholism. Physiol. Behav. 81, 339-358
    • (2004) Physiol. Behav , vol.81 , pp. 339-358
    • Oswald, L.M.1    Wand, G.S.2
  • 37
    • 0037135151 scopus 로고    scopus 로고
    • Orphanin FQ/nociceptin and mu-opioid receptor mRNA levels in human SH-SY5Y neuroblastoma cells: Effects of activating the cAMP-PKA signal transduction pathway
    • Wallington, C. L., Peters, D. M., Gelb, C. R., and Peterfreund, R. A. (2002) Orphanin FQ/nociceptin and mu-opioid receptor mRNA levels in human SH-SY5Y neuroblastoma cells: effects of activating the cAMP-PKA signal transduction pathway. Brain Res. 944, 73-81
    • (2002) Brain Res , vol.944 , pp. 73-81
    • Wallington, C.L.1    Peters, D.M.2    Gelb, C.R.3    Peterfreund, R.A.4
  • 38
    • 0036168649 scopus 로고    scopus 로고
    • Ethanol, acetaldehyde, acetate, and lactate levels after alcohol intake in white men and women: Effect of 4-methylpyrazole
    • Sarkola, T., Iles, M. R., Kohlenberg-Mueller, K., and Eriksson, C. J. (2002) Ethanol, acetaldehyde, acetate, and lactate levels after alcohol intake in white men and women: effect of 4-methylpyrazole. Alcohol. Clin. Exp. Res. 26, 239-245
    • (2002) Alcohol. Clin. Exp. Res , vol.26 , pp. 239-245
    • Sarkola, T.1    Iles, M.R.2    Kohlenberg-Mueller, K.3    Eriksson, C.J.4
  • 39
    • 0028329284 scopus 로고
    • Alcohol consumption and alcohol pharmacokinetics: Interactions within the normal population
    • Whitfield, J. B., and Martin, N. G. (1994) Alcohol consumption and alcohol pharmacokinetics: interactions within the normal population. Alcohol. Clin. Exp. Res. 18, 238-243
    • (1994) Alcohol. Clin. Exp. Res , vol.18 , pp. 238-243
    • Whitfield, J.B.1    Martin, N.G.2
  • 40
    • 0021214355 scopus 로고
    • Enhanced activity of the endorphinergic system in the anterior and neurointermediate lobe of the pituitary gland after chronic treatment with ethanol liquid diet
    • Seizinger, B. R., Bovermann, K., Hollt, V., and Herz, A. (1984) Enhanced activity of the endorphinergic system in the anterior and neurointermediate lobe of the pituitary gland after chronic treatment with ethanol liquid diet. J. Pharmacol. Exp. Ther. 230, 455-461
    • (1984) J. Pharmacol. Exp. Ther , vol.230 , pp. 455-461
    • Seizinger, B.R.1    Bovermann, K.2    Hollt, V.3    Herz, A.4
  • 41
    • 0023903651 scopus 로고
    • Effects of ethanol treatment and withdrawal on the biosynthesis and processing of pro-opiomelanocortin by the rat neurointermediate lobe
    • Gianoulakis, C., Hutchison, W. D., and Kalant, H. (1988) Effects of ethanol treatment and withdrawal on the biosynthesis and processing of pro-opiomelanocortin by the rat neurointermediate lobe. Endocrinology 122, 817-825
    • (1988) Endocrinology , vol.122 , pp. 817-825
    • Gianoulakis, C.1    Hutchison, W.D.2    Kalant, H.3
  • 43
    • 0022658373 scopus 로고
    • Ethanol exposure decreases pituitary corticotropin-releasing factor binding, adenylate cyclase activity, proopiomelanocortin biosynthesis and plasma β-endorphin levels in the rat
    • Dave, J. R., Eiden, L. E., Karanian, J. W., and Eskay, R. L. (1986) Ethanol exposure decreases pituitary corticotropin-releasing factor binding, adenylate cyclase activity, proopiomelanocortin biosynthesis and plasma β-endorphin levels in the rat. Endocrinology 118, 280-286
    • (1986) Endocrinology , vol.118 , pp. 280-286
    • Dave, J.R.1    Eiden, L.E.2    Karanian, J.W.3    Eskay, R.L.4
  • 44
    • 0029026776 scopus 로고
    • Effects of voluntary ethanol ingestion on the POMC gene expression in the rat pituitary and on the plasma beta-endorphin content
    • Winkler, A., Roske, I., Furkert, J., Fickel, J., and Melzig, M. F. (1995) Effects of voluntary ethanol ingestion on the POMC gene expression in the rat pituitary and on the plasma beta-endorphin content. Alcohol Alcohol. 30, 231-238
    • (1995) Alcohol Alcohol , vol.30 , pp. 231-238
    • Winkler, A.1    Roske, I.2    Furkert, J.3    Fickel, J.4    Melzig, M.F.5
  • 45
    • 1642337210 scopus 로고    scopus 로고
    • Chronic ethanol consumption impairs the circadian rhythm of pro-opiomelanocortin and period genes mRNA expression in the hypothalamus of the male rat
    • Chen, C. P., Kuhn, P., Advis, J. P., and Sarkar, D. K. (2004) Chronic ethanol consumption impairs the circadian rhythm of pro-opiomelanocortin and period genes mRNA expression in the hypothalamus of the male rat. J. Neurochem. 88, 1547-1554
    • (2004) J. Neurochem , vol.88 , pp. 1547-1554
    • Chen, C.P.1    Kuhn, P.2    Advis, J.P.3    Sarkar, D.K.4
  • 46
    • 0033777377 scopus 로고    scopus 로고
    • Reduced hypothalamic POMC and anterior pituitary CRF1 receptor mRNA levels after acute, but not chronic, daily "binge" intragastric alcohol administration
    • Zhou, Y., Franck, J., Spangler, R., Maggos, C. E., Ho, A., and Kreek, M. J. (2000) Reduced hypothalamic POMC and anterior pituitary CRF1 receptor mRNA levels after acute, but not chronic, daily "binge" intragastric alcohol administration. Alcohol. Clin. Exp. Res. 24, 1575-1582
    • (2000) Alcohol. Clin. Exp. Res , vol.24 , pp. 1575-1582
    • Zhou, Y.1    Franck, J.2    Spangler, R.3    Maggos, C.E.4    Ho, A.5    Kreek, M.J.6
  • 47
    • 0027481155 scopus 로고
    • Chronic ethanol increases proopiomelanocortin gene expression in the rat hypothalamus
    • Gianoulakis, C., and Angelogianni, P. (1993) Chronic ethanol increases proopiomelanocortin gene expression in the rat hypothalamus. Neuroendocrinology 57, 106-114
    • (1993) Neuroendocrinology , vol.57 , pp. 106-114
    • Gianoulakis, C.1    Angelogianni, P.2
  • 48
    • 0036118017 scopus 로고    scopus 로고
    • Chronic daily ethanol and withdrawal: 3. Forebrain pro-opiomelanocortin gene expression and implications for dependence, relapse, and deprivation effect
    • Rasmussen, D. D., Boldt, B. M., Wilkinson, C. W., and Mitton, D. R. (2002) Chronic daily ethanol and withdrawal: 3. Forebrain pro-opiomelanocortin gene expression and implications for dependence, relapse, and deprivation effect. Alcohol. Clin. Exp. Res. 26, 535-546
    • (2002) Alcohol. Clin. Exp. Res , vol.26 , pp. 535-546
    • Rasmussen, D.D.1    Boldt, B.M.2    Wilkinson, C.W.3    Mitton, D.R.4
  • 49
    • 17444398159 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide and corticotropin-releasing hormone increase beta-endorphin release and proopiomelanocortin messenger RNA levels in primary cultures of hypothalamic cells: Effects of acute and chronic ethanol treatment
    • Poplawski, M. M., Boyadjieva, N., and Sarkar, D. K. (2005) Vasoactive intestinal peptide and corticotropin-releasing hormone increase beta-endorphin release and proopiomelanocortin messenger RNA levels in primary cultures of hypothalamic cells: effects of acute and chronic ethanol treatment. Alcohol. Clin. Exp. Res. 29, 648-655
    • (2005) Alcohol. Clin. Exp. Res , vol.29 , pp. 648-655
    • Poplawski, M.M.1    Boyadjieva, N.2    Sarkar, D.K.3
  • 50
    • 20144379546 scopus 로고    scopus 로고
    • Alteration of kappa-opioid receptor system expression in distinct brain regions of a genetic model of enhanced ethanol withdrawal severity
    • Beadles-Bohling, A. S., and Wiren, K. M. (2005) Alteration of kappa-opioid receptor system expression in distinct brain regions of a genetic model of enhanced ethanol withdrawal severity. Brain Res. 1046, 77-89
    • (2005) Brain Res , vol.1046 , pp. 77-89
    • Beadles-Bohling, A.S.1    Wiren, K.M.2
  • 51
    • 0034863007 scopus 로고    scopus 로고
    • Alterations in central preproenkephalin mRNA expression after chronic free-choice ethanol consumption by fawn-hooded rats
    • Cowen, M. S., and Lawrence, A. J. (2001) Alterations in central preproenkephalin mRNA expression after chronic free-choice ethanol consumption by fawn-hooded rats. Alcohol. Clin. Exp. Res. 25, 1126-1133
    • (2001) Alcohol. Clin. Exp. Res , vol.25 , pp. 1126-1133
    • Cowen, M.S.1    Lawrence, A.J.2
  • 52
    • 0028062829 scopus 로고
    • Differences between alcohol-preferring (AA) and alcohol-avoiding (ANA) rats in the prodynorphin and proenkephalin systems
    • Nylander, I., Hyytia, P., Forsander, O., and Terenius, L. (1994) Differences between alcohol-preferring (AA) and alcohol-avoiding (ANA) rats in the prodynorphin and proenkephalin systems. Alcohol. Clin. Exp. Res. 18, 1272-1279
    • (1994) Alcohol. Clin. Exp. Res , vol.18 , pp. 1272-1279
    • Nylander, I.1    Hyytia, P.2    Forsander, O.3    Terenius, L.4
  • 53
    • 12544256888 scopus 로고    scopus 로고
    • Alcohol and gene expression in the central nervous system
    • Worst, T. J., and Vrana, K. E. (2005) Alcohol and gene expression in the central nervous system. Alcohol Alcohol. 40, 63-75
    • (2005) Alcohol Alcohol , vol.40 , pp. 63-75
    • Worst, T.J.1    Vrana, K.E.2
  • 54
    • 0032870007 scopus 로고    scopus 로고
    • Downregulation of kappa opioid receptor mRNA levels by chronic ethanol and repetitive cocaine in rat ventral tegmentum and nucleus accumbens
    • Rosin, A., Lindholm, S., Franck, J., and Georgieva, J. (1999) Downregulation of kappa opioid receptor mRNA levels by chronic ethanol and repetitive cocaine in rat ventral tegmentum and nucleus accumbens. J. Neurosci. Lett. 275, 1-4
    • (1999) J. Neurosci. Lett , vol.275 , pp. 1-4
    • Rosin, A.1    Lindholm, S.2    Franck, J.3    Georgieva, J.4
  • 55
    • 0026490942 scopus 로고
    • Modification of proteins and other biological molecules by acetaldehyde: Adduct structure and functional significance
    • Nicholls, R., de Jersey, J., Worrall, S., and Wilce, P. (1992) Modification of proteins and other biological molecules by acetaldehyde: adduct structure and functional significance. International J. Biochem. 24, 1899-1906
    • (1992) International J. Biochem , vol.24 , pp. 1899-1906
    • Nicholls, R.1    de Jersey, J.2    Worrall, S.3    Wilce, P.4
  • 56
    • 20044365114 scopus 로고    scopus 로고
    • Impact of ethanol and acetaldehyde on DNA and cell viability of cultured neurones
    • Lamarche, F., Gonthier, B., Signorini, N., Eysseric, H., and Barret, L. (2004) Impact of ethanol and acetaldehyde on DNA and cell viability of cultured neurones. Cell Biol. Toxicol. 20, 361-374
    • (2004) Cell Biol. Toxicol , vol.20 , pp. 361-374
    • Lamarche, F.1    Gonthier, B.2    Signorini, N.3    Eysseric, H.4    Barret, L.5
  • 57
    • 0023463235 scopus 로고
    • Effects of alcohol and acetaldehyde on metabolism and function of neurotransmitter systems in cerebral cortical neurons in primary culture
    • Kuriyama, K., Ohkuma, S., Tomono, S., and Hirouchi, M. (1987) Effects of alcohol and acetaldehyde on metabolism and function of neurotransmitter systems in cerebral cortical neurons in primary culture. Alcohol. Alcohol. Suppl. 1, 685-689
    • (1987) Alcohol. Alcohol. Suppl , vol.1 , pp. 685-689
    • Kuriyama, K.1    Ohkuma, S.2    Tomono, S.3    Hirouchi, M.4
  • 58
    • 0030916621 scopus 로고    scopus 로고
    • Forskolin delays the ethanol-induced desensitization of hypothalamic beta-endorphin neurons in primary cultures
    • Boyadjieva, N., Reddy, B. V., and Sarkar, D. K. (1997) Forskolin delays the ethanol-induced desensitization of hypothalamic beta-endorphin neurons in primary cultures. Alcohol. Clin. Exp. Res. 21, 477-482
    • (1997) Alcohol. Clin. Exp. Res , vol.21 , pp. 477-482
    • Boyadjieva, N.1    Reddy, B.V.2    Sarkar, D.K.3
  • 59
    • 0028598240 scopus 로고
    • Comparison of the effects of alcohol and acetaldehyde on proopiomelanocortin mRNA levels and beta-endorphin secretion from hypothalamic neurons in primary cultures
    • Pastorcic, M., Boyadjieva, N., and Sarkar, D. K. (1994) Comparison of the effects of alcohol and acetaldehyde on proopiomelanocortin mRNA levels and beta-endorphin secretion from hypothalamic neurons in primary cultures. Mol. Cell Neurosci. 5, 580-586
    • (1994) Mol. Cell Neurosci , vol.5 , pp. 580-586
    • Pastorcic, M.1    Boyadjieva, N.2    Sarkar, D.K.3
  • 60
    • 0030047302 scopus 로고    scopus 로고
    • Acetaldehyde-induced growth inhibition in cultured rat astroglial cells
    • Holownia, A., Ledig, M., Mapoles, J., and Menez, J. F. (1996) Acetaldehyde-induced growth inhibition in cultured rat astroglial cells. Alcohol 13, 93-97
    • (1996) Alcohol , vol.13 , pp. 93-97
    • Holownia, A.1    Ledig, M.2    Mapoles, J.3    Menez, J.F.4
  • 61
    • 0030901249 scopus 로고    scopus 로고
    • Ethanol-induced cell death in cultured rat astroglia
    • Holownia, A., Ledig, M., and Menez, J. F. (1997) Ethanol-induced cell death in cultured rat astroglia. Neurotoxicol. Teratol. 19, 141-146
    • (1997) Neurotoxicol. Teratol , vol.19 , pp. 141-146
    • Holownia, A.1    Ledig, M.2    Menez, J.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.