Orphanin FQ/nociceptin and μ-opioid receptor mRNA levels in human SH-SY5Y neuroblastoma cells: Effects of activating the cAMP-PKA signal transduction pathway

Brain Research

Volumn 944, Issue 1-2, 2002, Pages 73-81

  Wallington, Cara Louise ^a   Peters, Dawn M ^a   Gelb, Carol R ^a   Peterfreund, Robert A ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Opioid receptor; cAMP; mRNA; Orphanin FQ nociceptin receptor; Protein kinase A; SH SY5Y neuroblastoma cell

Indexed keywords

4 (3 BUTOXY 4 METHOXYBENZYL) 2 IMIDAZOLIDINONE; CHOLERA TOXIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; DIDEOXYFORSKOLIN; FORSKOLIN; FORSKOLIN DERIVATIVE; ISOBUTYLMETHYLXANTHINE; MESSENGER RNA; MU OPIATE RECEPTOR; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; NOCICEPTIN; NOCICEPTIN RECEPTOR; PHOSPHODIESTERASE INHIBITOR; PROTEIN SYNTHESIS INHIBITOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; VASOACTIVE INTESTINAL POLYPEPTIDE;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYBRIDIZATION; INCUBATION TIME; MOLECULAR PROBE; MONOLAYER CULTURE; NEUROBLASTOMA; NEUROBLASTOMA CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; SIGNAL TRANSDUCTION;

ANALGESICS, OPIOID; CENTRAL NERVOUS SYSTEM; CHOLERA TOXIN; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOWN-REGULATION; DRUG TOLERANCE; ENZYME INHIBITORS; FORSKOLIN; GENE EXPRESSION REGULATION; HUMANS; NEUROBLASTOMA; OLIGONUCLEOTIDE PROBES; PROTEIN SYNTHESIS INHIBITORS; RECEPTORS, OPIOID; RECEPTORS, OPIOID, MU; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; UP-REGULATION; VASOACTIVE INTESTINAL PEPTIDE;

EID: 0037135151     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(02)02720-8     Document Type: Article

References (38)

1. Calcium regulation of vasoactive intestinal polypeptide mRNA abundance in SH-SY5Y human neuroblastoma cells
2. Genomic structure of the mouse δ-opioid receptor gene
3. Retinoic acid-induced increase in δ-opioid receptor and N-methyl-D-aspartate receptor mRNA levels in neuroblastoma×glioma (NG108-15) cells
4. Inducible expression of N-methyl-D-aspartate receptor, and δ and μ opioid receptor messenger RNAs and protein in the human NT2-N cell line
5. Regulation of δ-opioid receptor mRNA levels by receptor-mediated and direct activation of the adenylyl cyclase-protein kinase A pathway
6. Activation of type II adenylyl cyclase by the cloned μ-opioid receptor: Coupling to multiple G proteins
7. Demonstration of K3-opioid receptors in the SH-SY5Y human neuroblastoma cell line
8. Opioid tolerance: The clinical perspective
9. 2+ in the SH-SY5Y human neuroblastoma cell line
10. 1 ganglioside-regulated opioid receptor functions
11. International Union of Pharmacology. XII. Classification of opioid receptors
12. Regulation of μ-opioid receptor mRNA levels by activation of protein kinase C in human SH-SY5Y neuroblastoma cells
13. Opiate tolerance and dependence: Receptors. G-Proteins and antiopiates
14. μ-Opioid receptor internalization: Opiate drugs have differential effects on a conserved endocytic mechanism in vitro and in the mammalian brain
15. Molecular cloning and functional analysis of the rat μ-opioid receptor gene promoter
16. Opioid receptors
17. Regulation of opioid receptor activities
18. Cloning and characterization of the promoter region of the mouse μ opioid receptor gene
19. Reduction of morphine abstinence in mice with a mutation in the gene encoding CREB
20. The association of neuropathic pain, morphine tolerance and dependence, and the translocation of protein kinase C
21. 1 receptor
22. Protein kinase C regulates adenosine A2a receptor mRNA expression in SH-SY5Y cells
23. Progesterone increases levels of μ-opioid receptor mRNA in the preoptic area and arcuate nucleus of ovariectomized, estradiol-treated female rats
24. Spinal opioid μ receptor expression in lumbar spinal cord of rats following nerve injury
25. Molecular mechanisms of agonist-induced desensitization of the cloned mouse κ-opioid receptor
26. Characterization of the cloned human μ-opioid receptor
27. Opiate receptors
28. The interleukin-1b-mediated regulation of proenkephalin and opioid receptor messenger RNA in primary astrocyte enriched cultures
29. Interleukin-1β-mediated regulation of μ-opioid receptor mRNA in primary astrocyte enriched cultures
30. Role of cAMP-dependent protein kinase (PKA) in opioid agonist-induced μ-opioid receptor downregulation and tolerance in mice
31. Interleukin-1 induces the expression of μ-opioid receptors in endothelial cells
32. Protein kinase A maintains cellular tolerance to μ-opioid receptor agonists in hypothalamic neurosecretory cells with chronic morphine treatment: Convergence on a common pathway with estrogen in modulating μ-opioid receptor/effector coupling
33. The human μ-opioid receptor gene: 5′ regulatory and intronic sequences
34. Regulation of mouse δ-opioid receptor gene transcription: Involvement of the transcription factors AP-1 and AP-2
35. Chronic fentanyl treatments induce the upregulation of μ-opioid receptor mRNA in rat pheochromocytoma cells
36. μ-Opiate receptor downregulation by morphine and upregulation by naloxone in SH-SY5Y human neuroblastoma cells
37. Differential μ-opiate receptor phosphorylation and desensitization induced by agonists and phorbol esters
38. Downregulation of μ-opioid receptors in rat and monkey dorsal root ganglion neurons and spinal cord after peripheral axotomy