Heterologous influenza vRNA segments with identical non-coding sequences stimulate viral RNA replication in trans

Virology Journal

Volumn 5, Issue , 2008, Pages

  Ng, Stella S F ^a   Li, Olive T W ^a   Cheung, Timothy K W ^a   Malik Peiris, J S ^a   Poon, Leo L M ^a  

^a THE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; SIALIDASE; UNTRANSLATED RNA; VIRUS PROTEIN; VIRUS RNA; NS PROTEIN, INFLUENZA VIRUS; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ARTICLE; INFLUENZA VIRUS A; NONHUMAN; NUCLEOTIDE SEQUENCE; RNA REPLICATION; RNA SEQUENCE; RNA SYNTHESIS; SEQUENCE ANALYSIS; TRANSCRIPTION INITIATION; VIRUS MUTANT; VIRUS RECOMBINANT; VIRUS REPLICATION; CELL LINE; CHEMISTRY; GENETIC TRANSCRIPTION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PHYSIOLOGY; VIRUS GENOME;

INFLUENZA A VIRUS;

3' UNTRANSLATED REGIONS; 5' UNTRANSLATED REGIONS; CELL LINE; GENOME, VIRAL; INFLUENZA A VIRUS; NEURAMINIDASE; RNA, MESSENGER; RNA, VIRAL; TRANSCRIPTION, GENETIC; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

EID: 40449116417     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/1743-422X-5-2     Document Type: Article

References (35)

1. Orthomyxoviridae: The viruses and their replication. RF Lamb RM Krug, Fields virology Philadelphia: Lippincott-Raven Publishers, Knipe DM, Howley PH, 3 1996 353 1395
2. Characterization of the polyadenylation signal of influenza virus RNA. X Li P Palese, J Virol 1994 68 1245 1249 7507179
3. Polyadenylation sites for influenza virus mRNA. JS Robertson M Schubert RA Lazzarini, J Virol 1981 38 157 163 7241649
4. Direct evidence that the poly(A) tail of influenza A virus mRNA is synthesized by reiterative copying of a U track in the virion RNA template. LL Poon DC Pritlove E Fodor GG Brownlee, J Virol 1999 73 3473 3476 10074205
5. Influenza A virus RNA polymerase has the ability to stutter at the polyadenylation site of a viral RNA template during RNA replication. H Zheng HA Lee P Palese A Garcia-Sastre, J Virol 1999 73 5240 5243 10233995
6. Orthomyxovirus replication, transcription, and polyadenylation. G Neumann GG Brownlee E Fodor Y Kawaoka, Curr Top Microbiol Immunol 2004 283 121 143 15298169
7. Different de novo initiation strategies are used by influenza virus RNA polymerase on its cRNA and viral RNA promoters during viral RNA replication. T Deng FT Vreede GG Brownlee, J Virol 2006 80 2337 2348 16474140 10.1128/JVI.80.5.2337-2348.2006
8. Increased amounts of the influenza virus nucleoprotein do not promote higher levels of viral genome replication. AE Mullin RM Dalton MJ Amorim D Elton P Digard, J Gen Virol 2004 85 3689 3698 10.1099/vir.0.80518-0 15557242
9. Influenza virion-derived viral ribonucleoproteins synthesize both mRNA and cRNA in vitro. FT Vreede GG Brownlee, J Virol 2007 81 2196 2204 17166911 10.1128/JVI.02187-06
10. Model suggesting that replication of influenza virus is regulated by stabilization of replicative intermediates. FT Vreede TE Jung GG Brownlee, J Virol 2004 78 9568 9572 15308750 10.1128/JVI.78.17.9568-9572.2004
11. The 3' and 5'-terminal sequences of influenza A, B and C virus RNA segments are highly conserved and show partial inverted complementarity. U Desselberger VR Racaniello JJ Zazra P Palese, Gene 1980 8 315 328 10.1016/0378-1119(80)90007-4 7358274
12. The influenza virus panhandle is involved in the initiation of transcription. E Fodor DC Pritlove GG Brownlee, J Virol 1994 68 4092 4096 8189550
13. Sequence-specific binding of the influenza virus RNA polymerase to sequences located at the 5' ends of the viral RNAs. LS Tiley M Hagen JT Matthews M Krystal, J Virol 1994 68 5108 5116 8035510
14. Recombinant influenza virus polymerase: requirement of both 5' and 3' viral ends for endonuclease activity. M Hagen TD Chung JA Butcher M Krystal, J Virol 1994 68 1509 1515 8107213
15. Activation of influenza virus RNA polymerase by the 5' and 3' terminal duplex of genomic RNA. MT Lee K Klumpp P Digard L Tiley, Nucleic Acids Res 2003 31 1624 1632 12626703 10.1093/nar/gkg253
16. Promoter elements in the influenza vRNA terminal structure. R Flick G Neumann E Hoffmann E Neumeier G Hobom, RNA 1996 2 1046 1057 8849780
17. Characterization of the RNA-fork model of virion RNA in the initiation of transcription in influenza A virus. E Fodor DC Pritlove GG Brownlee, J Virol 1995 69 4012 4019 7769659
18. Efficient generation and growth of influenza virus A/PR/8/34 from eight cDNA fragments. E de Wit MI Spronken TM Bestebroer GF Rimmelzwaan AD Osterhaus RA Fouchier, Virus Res 2004 103 155 161 10.1016/j.virusres.2004.02.028 15163504
19. The position 4 nucleotide at the 3' end of the influenza virus neuraminidase vRNA is involved in temporal regulation of transcription and replication of neuraminidase RNAs and affects the repertoire of influenza virus surface antigens. KH Lee BL Seong, J Gen Virol 1998 79 1923 1934 9714240
20. The generation of recombinant influenza A viruses expressing a PB2 fusion protein requires the conservation of a packaging signal overlapping the coding and noncoding regions at the 5' end of the PB2 segment. E Dos Santos Afonso N Escriou I Leclercq S van der Werf N Naffakh, Virology 2005 341 34 46 10.1016/j.virol.2005.06.040 16084555
21. Importance of both the coding and the segment-specific noncoding regions of the influenza A virus NS segment for its efficient incorporation into virions. K Fujii Y Fujii T Noda Y Muramoto T Watanabe A Takada H Goto T Horimoto Y Kawaoka, J Virol 2005 79 3766 3774 15731270 10.1128/JVI.79.6.3766-3774.2005
22. Selective incorporation of influenza virus RNA segments into virions. Y Fujii H Goto T Watanabe T Yoshida Y Kawaoka, Proc Natl Acad Sci USA 2003 100 2002 2007 12574509 10.1073/pnas.0437772100
23. cis-Acting packaging signals in the influenza virus PB1, PB2, and PA genomic RNA segments. Y Liang Y Hong TG Parslow, J Virol 2005 79 10348 10355 16051827 10.1128/JVI.79.16.10348-10355.2005
24. Exploitation of nucleic acid packaging signals to generate a novel influenza virus-based vector stably expressing two foreign genes. T Watanabe S Watanabe T Noda Y Fujii Y Kawaoka, J Virol 2003 77 10575 10583 12970442 10.1128/JVI.77.19.10575-10583.2003
25. Mutations in the nonconserved noncoding sequences of the influenza A virus segments affect viral vRNA formation. M Bergmann T Muster, Virus Res 1996 44 23 31 10.1016/0168-1702(96)01335-4 8873410
26. An influenza A virus containing influenza B virus 5' and 3' noncoding regions on the neuraminidase gene is attenuated in mice. T Muster EK Subbarao M Enami BR Murphy P Palese, Proc Natl Acad Sci USA 1991 88 5177 5181 2052599 10.1073/pnas.88.12.5177
27. Nonconserved nucleotides at the 3' and 5' ends of an influenza A virus RNA play an important role in viral RNA replication. H Zheng P Palese A Garcia-Sastre, Virology 1996 217 242 251 10.1006/viro.1996.0111 8599209
28. A DNA transfection system for generation of influenza A virus from eight plasmids. E Hoffmann G Neumann Y Kawaoka G Hobom RG Webster, Proc Natl Acad Sci USA 2000 97 6108 6113 10801978 10.1073/pnas.100133697
29. The RNA polymerase of influenza virus, bound to the 5' end of virion RNA, acts in cis to polyadenylate mRNA. LL Poon DC Pritlove J Sharps GG Brownlee, J Virol 1998 72 8214 8219 9733864
30. Transcription of the influenza virus genome. AJ Hay B Lomniczi AR Bellamy JJ Skehel, Virology 1977 83 337 355 10.1016/0042-6822(77)90179-9 929980
31. Mutational analysis of influenza A virus nucleoprotein: identification of mutations that affect RNA replication. I Mena E Jambrina C Albo B Perales J Ortin M Arrese D Vallejo A Portela, J Virol 1999 73 1186 1194 9882320
32. Surprising function of the three influenza viral polymerase proteins: selective protection of viral mRNAs against the cap-snatching reaction catalyzed by the same polymerase proteins. SR Shih RM Krug, Virology 1996 226 430 435 10.1006/viro.1996.0673 8955065
33. Temperature sensitive influenza A virus genome replication results from low thermal stability of polymerase-cRNA complexes. RM Dalton AE Mullin MJ Amorim E Medcalf LS Tiley P Digard, Virol J 2006 3 58 16934156 10.1186/1743-422X-3-58
34. Alternative base pairs attenuate influenza A virus when introduced into the duplex region of the conserved viral RNA promoter of either the NS or the PA gene. AP Catchpole LJ Mingay E Fodor GG Brownlee, J Gen Virol 2003 84 507 515 10.1099/vir.0.18795-0 12604800
35. Universal primer set for the full-length amplification of all influenza A viruses. E Hoffmann J Stech Y Guan RG Webster DR Perez, Arch Virol 2001 146 2275 2289 10.1007/s007050170002 11811679