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Volumn 5, Issue , 2007, Pages 213-242

The medicinal chemistry of the DATA and DAPY series of HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs)

(2)  Heeres, Jan a   Lewi, Paul J a  

a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 40449097507     PISSN: 10758593     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1075-8593(06)05006-4     Document Type: Review
Times cited : (25)

References (26)
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    • E. Arnold, K. Das, A.D. Clark Jr., S.H. Hughes, X-ray crystal structure of R147681 (TMC120) complexed with HIV-1 reverse transcriptase, Personal communication, CABM Rutgers University, New Jersey, 1999
    • E. Arnold, K. Das, A.D. Clark Jr., S.H. Hughes, X-ray crystal structure of R147681 (TMC120) complexed with HIV-1 reverse transcriptase, Personal communication, CABM Rutgers University, New Jersey, 1999
  • 4
    • 15444380338 scopus 로고    scopus 로고
    • From 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1- j k](1,4)benzodiazepin-2-(1H)-one (TIBO) to etravirine (TMC125): Fifteen years of research on non-nucleoside inhibitors of HIV-1 reverse transcriptase
    • De Corte B.L. From 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1- j k](1,4)benzodiazepin-2-(1H)-one (TIBO) to etravirine (TMC125): Fifteen years of research on non-nucleoside inhibitors of HIV-1 reverse transcriptase. J. Med. Chem. 48 (2005) 1689-1696
    • (2005) J. Med. Chem. , vol.48 , pp. 1689-1696
    • De Corte, B.L.1
  • 9
    • 48349095488 scopus 로고    scopus 로고
    • F. Goebel, A. Yakovlev, A. Pozniak, E. Vinogradova, P. Lewi, G. Boogaerts, R. Hoetelmans, M.-P. de Béthune, M. Peeters, B. Woodfall, TMC278: Potent anti-HIV activity in antiretroviral therapy-naïve patients. Abstract 160. Conf. Retrovirus Opportun. Infect., Boston, 22-25 February 2005
    • F. Goebel, A. Yakovlev, A. Pozniak, E. Vinogradova, P. Lewi, G. Boogaerts, R. Hoetelmans, M.-P. de Béthune, M. Peeters, B. Woodfall, TMC278: Potent anti-HIV activity in antiretroviral therapy-naïve patients. Abstract 160. Conf. Retrovirus Opportun. Infect., Boston, 22-25 February 2005
  • 12
    • 48349118941 scopus 로고    scopus 로고
    • Y. Ivanov, A. Lisitsa, I. Karuzina, A.I. Archakov, Atomic force microscopy of aggregates of R278474 (TMC278), Personal communication, Institute of Biomedical Chemistry, Russ. Acad. Sc., Moscow, 2004
    • Y. Ivanov, A. Lisitsa, I. Karuzina, A.I. Archakov, Atomic force microscopy of aggregates of R278474 (TMC278), Personal communication, Institute of Biomedical Chemistry, Russ. Acad. Sc., Moscow, 2004
  • 14
    • 0026693137 scopus 로고
    • Crystal structure at 3.5 Å resolution of HIV-1 reverse transcriptase complexed with an inhibitor
    • Kohlstaedt L.A., Wang J., Friedman J.M., Rice P.A., and Steitz T.A. Crystal structure at 3.5 Å resolution of HIV-1 reverse transcriptase complexed with an inhibitor. Science 256 (1992) 1783-1790
    • (1992) Science , vol.256 , pp. 1783-1790
    • Kohlstaedt, L.A.1    Wang, J.2    Friedman, J.M.3    Rice, P.A.4    Steitz, T.A.5
  • 24
    • 4644252952 scopus 로고    scopus 로고
    • A series of diaryltriazines and diarylpyrimidines are highly potent nonnucleoside reverse transcriptase inhibitors with possible applications as microbicides
    • Van Herrewege Y., Vanham G., Michiels J., Fransen K., Kestens L., Andries K., Janssen P., and Lewi P. A series of diaryltriazines and diarylpyrimidines are highly potent nonnucleoside reverse transcriptase inhibitors with possible applications as microbicides. Antimicrob. Agents Chemother. 48 (2004) 3684-3689
    • (2004) Antimicrob. Agents Chemother. , vol.48 , pp. 3684-3689
    • Van Herrewege, Y.1    Vanham, G.2    Michiels, J.3    Fransen, K.4    Kestens, L.5    Andries, K.6    Janssen, P.7    Lewi, P.8
  • 25
    • 15444366107 scopus 로고    scopus 로고
    • Concentration and pH dependent aggregation of hydrophobic drug molecules and relevance to oral bioavailability
    • Volovik Frenkel Y., Clark Jr. A.D., Das K., Wang Y.-H., Lewi P.J., Janssen P.A.J., and Arnold E. Concentration and pH dependent aggregation of hydrophobic drug molecules and relevance to oral bioavailability. J. Med. Chem. 48 (2005) 1974-1983
    • (2005) J. Med. Chem. , vol.48 , pp. 1974-1983
    • Volovik Frenkel, Y.1    Clark Jr., A.D.2    Das, K.3    Wang, Y.-H.4    Lewi, P.J.5    Janssen, P.A.J.6    Arnold, E.7
  • 26
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    • Y.-H. Wang, Y. Volovik Frenkel, E. Arnold, Electron microscopy of aggregates of R147681 (TMC120), Personal communication, CABM Rutgers Univ. and Univ. Med. Dentistry, New Jersey, 2003
    • Y.-H. Wang, Y. Volovik Frenkel, E. Arnold, Electron microscopy of aggregates of R147681 (TMC120), Personal communication, CABM Rutgers Univ. and Univ. Med. Dentistry, New Jersey, 2003


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.