Characterization of IgG autoantibodies to extracellular matrix protein 1 in lichen sclerosus

Clinical and Experimental Dermatology

Volumn 29, Issue 5, 2004, Pages 499-504

  Chan, I ^a   Oyama, N ^a   Neill, S M ^a   Wojnarowska, F ^b   Black, M M ^a   McGrath, J A ^a,c  

^a ST THOMAS HOSPITAL   (United Kingdom)

^b CHURCHILL HOSPITAL   (United Kingdom)

^c ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; BACTERIAL PROTEIN; EXTRACELLULAR MATRIX PROTEIN 1; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G2; RECOMBINANT PROTEIN; SCLEROPROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; AMINO TERMINAL SEQUENCE; ARTICLE; AUTOIMMUNE DISEASE; CARBOXY TERMINAL SEQUENCE; FEMALE; HUMAN; HUMORAL IMMUNITY; IMMUNOBLOTTING; LICHEN SCLEROSUS ET ATROPHICUS; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROTEIN DOMAIN;

ADULT; AGED; AGED, 80 AND OVER; AUTOANTIBODIES; EPITOPES; EXTRACELLULAR MATRIX PROTEINS; FEMALE; HUMANS; IMMUNOBLOTTING; IMMUNOGLOBULIN G; LICHEN SCLEROSUS ET ATROPHICUS; MIDDLE AGED; RECOMBINANT PROTEINS;

EID: 4043168304     PISSN: 03076938     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2230.2004.01573.x     Document Type: Article

References (33)

1. Meffert JJ, Davis BM, Grimwood RE. Liehen sclerosus. J Am Acad Dermatol 1995; 32: 393-416.
2. Powell JJ, Wojnarowska F. Lichen sclerosus. Lancet 1999; 353: 1777-83.
3. Tasker GL, Wojnarowska F. Lichen sclerosus. Clin Exp Dermatol 2003; 28: 128-33.
4. Meyrick-Thomas RH, Ridley CM, McGibbon DH et al. Liehen sclerosus et atrophicus and autoimmunity - a study of 350 women. Br J Dermatol 1998; 118: 41-6.
5. Wallace HJ. Lichen sclerosus et atrophicus. Trans St Johns Hosp Dermatol Soc 1971; 57: 9-30.
6. Ramrakha-Jones VS, Paul M, McHenry P et al. Nail dystrophy due to lichen sclerosus? Clin Exp Dermatol 2001; 26: 507-9.
7. Kossard S, Cornish N. Localised lichen sclerosus with nail loss. Australas J Dermatol 1998; 39: 119-20.
8. Neill SM, Tatnall FM, Cox NH. Guidelines for the management of lichen sclerosus. Br J Dermatol 2002; 147: 640-9.
9. Powell J, Wojnarowska F, Winsey S et al. Lichen sclerosus premenarche: autoimmunity and immunogenetics. Br J Dermatol 2000; 42: 481-4.
10. Azurdia RM, Luzzi GA, Byren I et al. Lichen sclerosus in adult men: a study of HLA associations and susceptibility to autoimmune disease. Br J Dermatol 1999; 140: 79-83.
11. Harrington CI, Dunsmore IR. An investigation into the incidence of auto-immune disorders in patients with lichen sclerosus and atrophicus. Br J Dermatol 1981; 104: 563-6.
12. Marren P, Dean D, Charnock M et al. The basement membrane zone in lichen sclerosus: an immunohistochemical study. Br J Dermatol 1997; 136: 508-14.
13. Howard A, Dean D, Cooper S et al. Circulating basement membrane zone antibodies are found in lichen sclerosus of the vulva. Aus J Dermatol 2004; 45: 12-5.
14. Oyama N, Chan I, Neill SM et al. Autoantibodies to extracellular matrix protein 1 in lichen sclerosus. Lancet 2003; 362: 118-23.
15. Hamada T. Lipoid proteinosis. Clin Exp Dermatol 2002; 27: 624-9.
16. Chan I. The role of extracellular matrix protein 1 in human skin. Clin Exp Dermatol 2004; 29: 52-6.
17. Mongiat M, Fu J, Oldershaw R et al. Perlecan protein core interacts with extracellular matrix protein 1 (ECM1), a glycoprotein involved in bone formation and angiogenesis. J Biol Chem 2003; 278: 17491-9.
18. Chan LS, Vanderlugt CJ, Hashimoto T et al. Epitope spreading: lessons from autoimmune skin diseases. J Invest Dermatol 1998; 110: 103-9.
19. Powell AM, Black MM. Epitope spreading, protection from pathogens, but propagation of autoimmunity? Clin Exp Dermatol 2001; 26: 427-33.
20. Skaria M, Jaunin F, Hunziker T et al. IgG autoantibodies from bullous pemphigoid patients recognize multiple antigenic reactive sites located predominantly within the B and C subdomains of the COOH-terminus of BP230. J Invest Dermatol 2000; 114: 998-1004.
21. Bonifacio E, Scirpoli M, Kredel K et al. Early autoantibody responses in prediabetes are IgG1 dominated and suggest antigen-specific regulation. J Immunol 1999; 163: 525-32.
22. Cook AD, Mackay IR, Cicuttini FM et al. IgG subclasses of antibodies to type II collagen in rheumatoid arthritis differ from those in systemic lupus erythematosus and other connective tissue diseases. J Rheumatol 1997; 24: 2090-6.
23. Kohno Y, Kijima M, Yamaguchi F et al. Comparison of the IgG subclass distribution of anti-thyroid peroxidase antibodies in healthy subjects with that in patients with chronic thyroiditis. Endocr J 1993; 40: 317-21.
24. Miyata M, Sato Y, Kasukawa R. IgG1 subclass specificity for IgG rheumatoid factors in patients with rheumatoid arthritis. J Rheumatol 1999; 26: 1436-8.
25. Outschoorn I, Rowley MJ, Cook AD et al. Subclasses of immunoglobulins and autoantibodies in autoimmune diseases. Clin Immunol Immunopathol 1993; 66: 59-66.
26. Chimanovitch I, Schmidt E, Messer G et al. IgG1 and IgG3 are the major immunoglobulin subclasses targeting epitopes within the NC16A domain of BP180 in pemphigoid gestationis. J Invest Dermatol 1999; 113: 140-2.
27. Hsu R, Lazarova Z, Yee C, Yancey KB. Noncomplement fixing, IgG4 autoantibodies predominate in patients with anti-epiligrin cicatricial pemphigoid. J Invest Dermatol 1997; 109: 557-61.
28. Jones CC, Hamilton RG, Jordon RE. Subclass distribution of human IgG autoantibodies in pemphigus. J Clin Immunol 1998; 8: 43-9.
29. Laffitte E, Skaria M, Jaunin F et al. Autoantibodies to the extracellular and intracellular domain of bullous pemphigoid 180, the putative key autoantigen in bullous pemphigoid, belong predominantly to the IgG1 and IgG4 subclasses. Br J Dermatol 2001; 144: 760-8.
30. Samarkos M, Davies KA, Gordon C et al. IgG subclass distribution of antibodies against β2-GP1 and cardiolipin in patients with systemic lupus erythematosus and primary antiphospholipid syndrome, and their clinical associations. Rheumatology 2001; 40: 1026-32.
31. Zuniga R, Markowitz GS, Arkachaisri T et al. Identification of IgG subclasses and C-reactive protein in lupus nephritis: The relationship between the composition of immune deposits and FC receptor type IIA alleles. Arthritis Rheum 2003; 48: 460-70.
32. Halpern GM. Critical evaluation of the clinical relevance of the IgG subclasses assays. Allerg Immunol 1993; 25: 10-8.
33. Romagnani S. Induction of TH1 and TH2 responses: a key role for the 'natural' immune response? Immunol Today 1992; 13: 379-81.