Cellulose membrane supported peptide arrays for deciphering protein-protein interaction sites: The case of PIN, a protein with multiple natural partners

Molecular Diversity

Volumn 8, Issue 3, 2004, Pages 281-290

  Lajoix, Anne Dominique ^a   Gross, René ^a   Aknin, Cindy ^a   Dietz, Samuel ^a   Granier, Claude ^a   Laune, Daniel ^a  

^a F   (France)

Author keywords

peptide array; PIN; spot technique

Indexed keywords

DYNEIN ADENOSINE TRIPHOSPHATASE; GEPHYRIN; MYOSIN V; NITRIC OXIDE SYNTHASE; TRANSCRIPTION FACTOR;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; HYDROPHOBICITY; MOLECULAR DYNAMICS; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROTEIN INTERACTION; RAT;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELLULOSE; DYNEIN ATPASE; INDICATORS AND REAGENTS; MOLECULAR SEQUENCE DATA; MYOSIN TYPE V; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; PEPTIDE FRAGMENTS; PEPTIDE LIBRARY; PROTEIN ARRAY ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEINS; RATS;

EID: 4043144340     PISSN: 13811991     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:MODI.0000036242.01129.27     Document Type: Article

References (35)

1. Mendelsohn, A. R. and Brent, R., Protein interaction methods - Toward an endgame, Science, 284 (1999) 1948-1950.
2. MacBeath, G., Protein microarrays and proteomics, Nat. Genet., 32 Suppl. (2002) 526-532.
3. Frank, R., Spot synthesis: An easy technique for the positionally addressable, parallel chemical synthesis on a membrane support, Tetrahedron, 48 (1992) 9217-9232.
4. Reineke, U., Volkmer-Engert, R. and Schneider-Mergener, J., Applications of peptide arrays prepared by the SPOT-technology, Curr. Opin. Biotechnol., 12 (2001) 59-64.
5. O'Neil, K. T. and DeGrado, W. F., How calmodulin binds its targets: Sequence independent recognition of amphiphilic alpha-helices, Trends Biochem. Sci., 15 (1990) 59-64.
6. Jaffrey, S. R. and Snyder, S. H., PIN: An associated protein inhibitor of neuronal nitric oxide synthase, Science, 274 (1996) 774-777.
7. King, S. M., Barbarese, E., Dillman, J. F., Patel-King, R. S., Carson, J. H. and Poster, K. K., Brain cytoplasmic and flagellar outer arm dyneins share a highly conserved Mr 8,000 light chain, J. Biol. Chem., 271 (1996) 19358-19366.
8. King, S. M. and Patel-King, R. S., The M(r) = 8,000 and 11,000 outer arm dynein light chains from Chlamydomonas flagella have cytoplasmic homologues, J. Biol. Chem., 270 (1995) 11445-11452.
9. Benashski, S. E., Harrison, A., Patel-King, R. S. and King, S. M., Dimerization of the highly conserved light chain shared by dynein and myosin V, J. Biol. Chem., 272 (1997) 20929-20935.
10. Espindola, F. S., Suter, D. M., Partata, L. B., Cao, T., Wolenski, J. S., Cheney, R. E., King, S. M. and Mooseker, M. S., The light chain composition of chicken brain myosin-Va: Calmodulin, myosin-II essential light chains, and 8-kDa dynein light chain/PIN, Cell Motil. Cytoskeleton, 47 (2000) 269-281.
11. Puthalakath, H., Huang, D. C., O'Reilly, L. A., King, S. M. and Strasser, A., The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex, Mol. Cell, 3 (1999) 287-296.
12. Crepieux, P., Kwon, H., Leclerc, N., Spencer, W., Richard, S., Lin, R. and Hiscott, J., I kappaB alpha physically interacts with a cytoskeleton- associated protein through its signal response domain, Mol. Cell. Biol. 17 (1997) 7375-7385.
13. Haraguchi, K., Satoh, K., Yanai, H., Hamada, F., Kawabuchi, M. and Akiyama, T., The hDLG-associated protein DAP interacts with dynein light chain and neuronal nitric oxide synthase, Genes Cells, 5 (2000) 905-911.
14. Naisbitt, S., Valtschanoff, J., Allison, D. W., Sala, C., Kim, E., Craig, A. M., Weinberg, R. J. and Sheng, M., Interaction of the postsynaptic density-95/guanylate kinase domain-associated protein complex with a light chain of myosin-V and dynein, J. Neurosci., 20 (2000) 4524-4534.
15. Herzig, R. P., Andersson, U. and Scarpulla, R. C., Dynein light chain interacts with NRF-1 and EWG, structurally and functionally related transcription factors from humans and drosophila, J. Cell Sci., 113 Pt 23 (2000) 4263-4273.
16. Fuhrmann, J. C., Kins, S., Rostaing, P., El Far, O., Kirsch, J., Sheng, M., Triller, A., Betz, H. and Kneussel, M., Gephyrin interacts with Dynein light chains 1 and 2, components of motor protein complexes, J. Neurosci., 22 (2002) 5393-5402.
17. Schnorrer, F., Bohmann, K. and Nusslein-Volhard, C., The molecular motor dynein is involved in targeting swallow and bicoid RNA to the anterior pole of Drosophila oocytes, Nat. Cell Biol., 2 (2000) 185-190.
18. Jacob, Y., Badrane, H., Ceccaldi, P. E. and Tordo, N., Cytoplasmic dynein LC8 interacts with lyssavirus phosphoprotein, J. Virol., 74 (2000) 10217-10222.
19. Raux, H., Flamand, A. and Blondel, D., Interaction of the rabies virus P protein with the LC8 dynein light chain, J. Virol., 74 (2000) 10212-10216.
20. Dick, T., Ray, K., Salz, H. K. and Chia, W., Cytoplasmic dynein (ddlc1) mutations cause morphogenetic defects and apoptotic cell death in Drosophila melanogaster, Mol. Cell. Biol., 16 (1996) 1966-1977.
21. Chang, Y. W., Jakobi, R., McGinty, A., Foschi, M., Dunn, M. J. and Sorokin, A., Cyclooxygenase 2 promotes cell survival by stimulation of dynein light chain expression and inhibition of neuronal nitric oxide synthase activity, Mol. Cell. Biol., 20 (2000) 8571-8579.
22. Liang, J., Jaffrey, S. R., Guo, W., Snyder, S. H. and Clardy, J., Structure of the PIN/LC8 dimer with a bound peptide, Nat. Struct. Biol., 6 (1999) 735-740.
23. Fan, J., Zhang, Q., Tochio, H., Li, M. and Zhang, M., Structural basis of diverse sequence-dependent target recognition by the 8 kDa dynein light chain, J. Mol. Biol., 306 (2001) 97-108.
24. Barbar, E., Hare, M., Makokha, M., Barany, G. and Woodward, C., Dimerization and folding of LC8, a highly conserved light chain of cytoplasmic dynein, Biochemistry, 40 (2001) 9734-9742.
25. Tochio, H., Ohki, S., Zhang, Q., Li, M. and Zhang, M., Solution structure of a protein inhibitor of neuronal nitric oxide synthase, Nat. Struct. Biol., 5 (1998) 965-969.
26. Laune, D., Molina, F., Ferrieres, G., Villard, S., Bes, C., Rieunier, F., Chardes, T. and Granier, C., Application of the Spot method to the identification of peptides and amino acids from the antibody paratope that contribute to antigen binding, J. Immunol. Methods, 267 (2002) 53-70.
27. Lo, K. W., Naisbitt, S., Fan, J. S., Sheng, M. and Zhang, M., The 8-kDa dynein light chain binds to its targets via a conserved (K/R)XTQT motif, J. Biol. Chem., 276 (2001) 14059-14066.
28. Rodriguez-Crespo, I., Yelamos, B., Roncal, F., Albar, J. P., Ortiz de Montellano, P. R. and Gavilanes, F., Identification of novel cellular proteins that bind to the LC8 dynein light chain using a pepscan technique, FEBS Lett., 503 (2001) 135-141.
29. Schneider, T. D. and Stephens, R. M., Sequence logos: A new way to display consensus sequences, Nucleic Acids Res., 18 (1990) 6097-6100.
30. Schwikowski, B., Uetz, P. and Fields, S., A network of protein-protein interactions in yeast, Nat. Biotechnol., 18 (2000) 1257-1261.
31. McCarty, J. S., Rudiger, S., Schonfeld, H. J., Schneider-Mergener, J., Nakahigashi, K., Yura, T. and Bukau, B., Regulatory region C of the E. coli heat shock transcription factor, sigma32, constitutes a DnaK binding site and is conserved among eubacteria, J. Mol. Biol., 256 (1996) 829-837.
32. Ferrieres, G., Pugniere, M., Mani, J. C., Villard, S., Laprade, M., Doutre, P., Pau, B. and Granier, C., Systematic mapping of regions of human cardiac troponin I involved in binding to cardiac troponin C: N- and C-terminal low affinity contributing regions, FEBS Lett., 479 (2000) 99-105.
33. Kramer, A., Keitel, T., Winkler, K., Stocklein, W., Hohne, W. and Schneider-Mergener, J., Molecular basis for the binding promiscuity of an anti-p24 (HIV-1) monoclonal antibody, Cell, 91 (1997) 799-809.
34. Borras, E., Martin, R., Judkowski, V., Shukaliak, J., Zhao, Y., Rubio-Godoy, V., Valmori, D., Wilson, D., Simon, R., Houghten, R. and Pinilla, C., Findings on T cell specificity revealed by synthetic combinatorial libraries, J. Immunol. Methods, 267 (2002) 79-97.
35. Fan, J. S., Zhang, Q., Tochio, H. and Zhang, M., Backbone dynamics of the 8 kDa dynein light chain dimer reveals molecular basis of the protein's functional diversity, J. Biomol. NMR, 23 (2002) 103-114.