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Volumn 78, Issue 7, 2004, Pages 384-389

Kinetics of orally administered di(2-ethylhexyl) phthalate and its metabolite, mono(2-ethylhexyl) phthalate, in male pigs

Author keywords

Chromatography; Di(2 ethylhexyl) phthalate (DEHP); Oral administration; Pharmacokinetics; Sus scrofa domestica

Indexed keywords

PHTHALIC ACID 2 ETHYLHEXYL MONOESTER; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER;

EID: 4043111963     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-004-0558-z     Document Type: Article
Times cited : (33)

References (24)
  • 2
    • 0022560397 scopus 로고
    • Absorption, metabolism, and excretion of di(2-ethylhexyl) phthalate by rats and mice
    • Albro PW (1986) Absorption, metabolism, and excretion of di(2-ethylhexyl) phthalate by rats and mice. Environ Health Perspect 65:293-298
    • (1986) Environ Health Perspect , vol.65 , pp. 293-298
    • Albro, P.W.1
  • 5
    • 4043120723 scopus 로고
    • TSCATS: OTS 0206634, Doc. I.D. 878212716, 06-20-83, Eastman Kodak Co
    • 14Cdi(2- ethylhexyl) phthalate in the rat. TSCATS: OTS 0206634, Doc. I.D. 878212716, 06-20-83, Eastman Kodak Co
    • (1983) 14Cdi(2-ethylhexyl) Phthalate in the Rat
  • 6
    • 0020328899 scopus 로고
    • Autoradiographic study of orally administered di-(2-ethylhexyl) phthalate in the mouse
    • Gaunt IF, Butterworth KR (1982) Autoradiographic study of orally administered di-(2-ethylhexyl) phthalate in the mouse. Food Chem Toxicol 20:215-217
    • (1982) Food Chem Toxicol , vol.20 , pp. 215-217
    • Gaunt, I.F.1    Butterworth, K.R.2
  • 7
    • 0034523473 scopus 로고    scopus 로고
    • Perinatal exposure to the phthalates DEHP, BBP, and DINP, but not DEP, DMP, or DOTP, alter sexual differentiation of the male rat
    • Gray LE, Ostby J, Furr J, Price M, Veeramachaneni DNR, Parks L (2000) Perinatal exposure to the phthalates DEHP, BBP, and DINP, but not DEP, DMP, or DOTP, alter sexual differentiation of the male rat. Toxicol Sci 58:350-365
    • (2000) Toxicol Sci , vol.58 , pp. 350-365
    • Gray, L.E.1    Ostby, J.2    Furr, J.3    Price, M.4    Veeramachaneni, D.N.R.5    Parks, L.6
  • 8
    • 0019136120 scopus 로고
    • Comparative distribution, excretion and metabolism of di-(2-ethylhexyl) phthalate in rats, dogs and miniature pigs
    • Ikeda GJ, Sapienza PP, Couvillion JL, Farber TM, van Loon EJ (1980) Comparative distribution, excretion and metabolism of di-(2-ethylhexyl) phthalate in rats, dogs and miniature pigs. Food Cosmet Toxicol 18:637-642
    • (1980) Food Cosmet Toxicol , vol.18 , pp. 637-642
    • Ikeda, G.J.1    Sapienza, P.P.2    Couvillion, J.L.3    Farber, T.M.4    Van Loon, E.J.5
  • 9
    • 0347877378 scopus 로고    scopus 로고
    • Di-2-ethylhexyl phthalate and di-n-butyl phthalate in the tissues of pigs and broiler chicks after their oral administration
    • Jarosová A, Gajdusková V, Raszyk J, Sevela K (1999) Di-2-ethylhexyl phthalate and di-n-butyl phthalate in the tissues of pigs and broiler chicks after their oral administration. Vet Med Czech 44:61-70
    • (1999) Vet Med Czech , vol.44 , pp. 61-70
    • Jarosová, A.1    Gajdusková, V.2    Raszyk, J.3    Sevela, K.4
  • 10
    • 0035083223 scopus 로고    scopus 로고
    • No background concentrations of di(2-ethylhexyl) phthalate and mono(2-ethylhexyl) phthalate in blood of rats
    • Kessler W, Phoka W, Csanády GA, Filser JG (2001) No background concentrations of di(2-ethylhexyl) phthalate and mono(2-ethylhexyl) phthalate in blood of rats. Arch Toxicol 75:62-64
    • (2001) Arch Toxicol , vol.75 , pp. 62-64
    • Kessler, W.1    Phoka, W.2    Csanády, G.A.3    Filser, J.G.4
  • 11
    • 0033030726 scopus 로고    scopus 로고
    • Quantitative evaluation of alternative mechanisms of blood and testes disposition of di(2-ethylhexyl) phthalate and mono(2-ethylhexyl) phthalate in rats
    • Keys DA, Wallace DG, Kepler TB, Conolly R (1999) Quantitative evaluation of alternative mechanisms of blood and testes disposition of di(2-ethylhexyl) phthalate and mono(2-ethylhexyl) phthalate in rats. Toxicol Sci 49:172-185
    • (1999) Toxicol Sci , vol.49 , pp. 172-185
    • Keys, D.A.1    Wallace, D.G.2    Kepler, T.B.3    Conolly, R.4
  • 12
    • 0035341453 scopus 로고    scopus 로고
    • Mono-(2-ethylhexyl) phthalate suppresses aromatase transcript levels and estradiol production in cultured rat granulosa cells
    • Lovekamp TN, Davis BJ (2001) Mono-(2-ethylhexyl) phthalate suppresses aromatase transcript levels and estradiol production in cultured rat granulosa cells. Toxicol Appl Pharmacol 172:217-224
    • (2001) Toxicol Appl Pharmacol , vol.172 , pp. 217-224
    • Lovekamp, T.N.1    Davis, B.J.2
  • 13
    • 0020395638 scopus 로고
    • Distribution and elimination of di-2-ethylhexyl phthalate (DEHP) and mono-2-ethylhexyl phthalate after a single oral administration of DEHP in rats
    • Oishi S, Hiraga K (1982) Distribution and elimination of di-2-ethylhexyl phthalate (DEHP) and mono-2-ethylhexyl phthalate after a single oral administration of DEHP in rats. Arch Toxicol 51:149-155
    • (1982) Arch Toxicol , vol.51 , pp. 149-155
    • Oishi, S.1    Hiraga, K.2
  • 14
    • 0022262335 scopus 로고
    • Effects of route of administration and repetitive dosing on the disposition of di(2-ethylhexyl) phthalate and its mono-de-esterified metabolite in rats
    • Pollack GM, Li RCK, Ermer JC, Shen DD (1985) Effects of route of administration and repetitive dosing on the disposition of di(2-ethylhexyl) phthalate and its mono-de-esterified metabolite in rats. Toxicol Appl Pharmacol 79:246-256
    • (1985) Toxicol Appl Pharmacol , vol.79 , pp. 246-256
    • Pollack, G.M.1    Li, R.C.K.2    Ermer, J.C.3    Shen, D.D.4
  • 15
    • 0030989774 scopus 로고    scopus 로고
    • Subchronic oral toxicity of di-n-octyl phthalate and di(2-ethylhexyl) phthalate in the rat
    • Poon R, Lecavalier P, Mueller R, Valli VE, Procter BG, Chu I (1997) Subchronic oral toxicity of di-n-octyl phthalate and di(2-ethylhexyl) phthalate in the rat. Food Chem Toxicol 35:225-239
    • (1997) Food Chem Toxicol , vol.35 , pp. 225-239
    • Poon, R.1    Lecavalier, P.2    Mueller, R.3    Valli, V.E.4    Procter, B.G.5    Chu, I.6
  • 17
    • 0022560399 scopus 로고
    • Comparative pharmacokinetics and sub-acute toxicity of di(2-ethylhexyl) phthalate (DEHP) in rats and marmosets: Extrapolation of effects in rodents to man
    • Rhodes C, Orton TC, Pratt IS, Batten PL, Bratt H, Jackson SJ, Elcombe CR (1986) Comparative pharmacokinetics and sub-acute toxicity of di(2-ethylhexyl) phthalate (DEHP) in rats and marmosets: extrapolation of effects in rodents to man. Environ Health Perspect 65:299-308
    • (1986) Environ Health Perspect , vol.65 , pp. 299-308
    • Rhodes, C.1    Orton, T.C.2    Pratt, I.S.3    Batten, P.L.4    Bratt, H.5    Jackson, S.J.6    Elcombe, C.R.7
  • 18
    • 0031704495 scopus 로고    scopus 로고
    • Hazard and risk assessment of chemical mixtures using the toxic equivalency factor approach
    • Safe SH (1998) Hazard and risk assessment of chemical mixtures using the toxic equivalency factor approach. Environ Health Perspect 106 [Suppl 4]:1051-1058
    • (1998) Environ Health Perspect , vol.106 , Issue.4 SUPPL. , pp. 1051-1058
    • Safe, S.H.1
  • 19
    • 0021823729 scopus 로고
    • Secretion and metabolism of di-(2-ethylhexyl) phthalate in man
    • Schmid P, Schlatter C (1985) Secretion and metabolism of di-(2-ethylhexyl) phthalate in man. Xenobiotika 15:251-256
    • (1985) Xenobiotika , vol.15 , pp. 251-256
    • Schmid, P.1    Schlatter, C.2
  • 21
    • 0022500653 scopus 로고
    • Effects of di-(2-ethylhexyl) phthalate and five of its metabolites on rat testis in vivo and in vitro
    • Sjöberg P, Bondesson U, Gray TJB, Plöen L (1986) Effects of di-(2-ethylhexyl) phthalate and five of its metabolites on rat testis in vivo and in vitro. Acta Pharmacol Toxicol 58:225-233
    • (1986) Acta Pharmacol Toxicol , vol.58 , pp. 225-233
    • Sjöberg, P.1    Bondesson, U.2    Gray, T.J.B.3    Plöen, L.4
  • 22
    • 0016741585 scopus 로고
    • Biochemical studies on phthalic esters. I. Elimination, distribution and metabolism of di-(2-ethylhexyl) phthalate in rats
    • Tanaka A, Adachi T, Takahashi T, Yamaha T (1975) Biochemical studies on phthalic esters. I. Elimination, distribution and metabolism of di-(2-ethylhexyl) phthalate in rats. Toxicology 4:253-264
    • (1975) Toxicology , vol.4 , pp. 253-264
    • Tanaka, A.1    Adachi, T.2    Takahashi, T.3    Yamaha, T.4
  • 23
    • 0022227665 scopus 로고
    • Disposition of orally administered di-(2-ethylhexyl) phthalate and mono-(2-ethylhexyl) phthalate in the rat
    • Teirlynck OA, Belpaire F (1985) Disposition of orally administered di-(2-ethylhexyl) phthalate and mono-(2-ethylhexyl) phthalate in the rat. Arch Toxicol 57:226-230
    • (1985) Arch Toxicol , vol.57 , pp. 226-230
    • Teirlynck, O.A.1    Belpaire, F.2
  • 24
    • 0019307438 scopus 로고
    • Absorption and metabolism of three phthalate diesters by the rat small intestine
    • White RD, Carter DE, Earnest D, Mueller J (1980) Absorption and metabolism of three phthalate diesters by the rat small intestine. Food Cosmet Toxicol 18:383-386
    • (1980) Food Cosmet Toxicol , vol.18 , pp. 383-386
    • White, R.D.1    Carter, D.E.2    Earnest, D.3    Mueller, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.