Myeloperoxidase enhances nitric oxide catabolism during myocardial ischemia and reperfusion

Free Radical Biology and Medicine

Volumn 37, Issue 6, 2004, Pages 902-911

  Baldus, Stephan ^a   Heitzer, Thomas ^a   Eiserich, Jason P ^b   Lau, Denise ^a   Mollnau, Hanke ^c   Ortak, Michelle ^a   Petri, Susan ^a   Goldmann, Britta ^a   Duchstein, Hans Jürgen ^a   Berger, Jürgen ^d   Helmchen, Udo ^a   Freeman, Bruce A ^e   Meinertz, Thomas ^a   Münzel, Thomas ^c  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^d UNIVERSITY OF HAMBURG   (Germany)

^e UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Endothelial dysfunction; Free radicals; Hydrogen peroxide; Myeloperoxidase; Myocardial infarction; Nitric oxide; Polymorphonuclear neutrophils; Reperfusion

Indexed keywords

ACETYLCHOLINE; HYDROGEN PEROXIDE; MYELOPEROXIDASE; NITRIC OXIDE;

ADULT; AGED; ARTICLE; BIOAVAILABILITY; CATABOLISM; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CORRELATION ANALYSIS; FEMALE; FOREARM BLOOD FLOW; HEART; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HUMAN; IMMUNOREACTIVITY; INFLAMMATION; INFORMATION PROCESSING; MALE; NEUTROPHIL; PRIORITY JOURNAL; VASCULAR DISEASE; VASOMOTOR REFLEX;

AGED; ANIMALS; ANTIGENS, CD31; CASE-CONTROL STUDIES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HEME; HUMANS; HYDROGEN PEROXIDE; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; MYOCARDIAL INFARCTION; MYOCARDIAL ISCHEMIA; MYOCARDIUM; NEUTROPHILS; NITRIC OXIDE; PEROXIDASE; RABBITS; REGIONAL BLOOD FLOW; REPERFUSION; REPERFUSION INJURY; TIME FACTORS;

ANIMALIA;

EID: 4043072706     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2004.06.003     Document Type: Article

References (34)

1. Verma S., Fedak P.W., Weisel R.D., Butany J., Rao V., Maitland A., Li R.K., Dhillon B., Yau T.M. Fundamentals of reperfusion injury for the clinical cardiologist. Circulation. 105:2002;2332-2336
2. Carden D.L., Granger D.N. Pathophysiology of ischemia-reperfusion injury. J. Pathol. 190:2000;255-266
3. Granger D.N. Ischemia-reperfusion: mechanisms of microvascular dysfunction and the influence of risk factors for cardiovascular disease. Microcirculation. 6:1999;167-178
4. Rezkalla S.H., Kloner R.A. No-reflow phenomenon. Circulation. 105:2002;656-662
5. Lefer A.M., Tsao P.S., Ma X.L. Shock- and ischemia-induced mechanisms of impairment of endothelium-mediated vasodilation. Chest. 100:1991;160S-163S
6. Aslan M., Ryan T.M., Adler B., Townes T.M., Parks D.A., Thompson J.A., Tousson A., Gladwin M.T., Patel R.P., Tarpey M.M., Batinic-Haberle I., White C.R., Freeman B.A. Oxygen radical inhibition of nitric oxide-dependent vascular function in sickle cell disease. Proc. Natl. Acad. Sci. USA. 98:2001;15215-15220
7. Babior B.M. Phagocytes and oxidative stress. Am. J. Med. 109:2000;33-44
8. Kurose I., Argenbright L.W., Wolf R., Lianxi L., Granger D.N. Ischemia/reperfusion-induced microvascular dysfunction: role of oxidants and lipid mediators. Am. J. Physiol. 272:1997;H2976-H2982
9. Daugherty A., Dunn J.L., Rateri D.L., Heinecke J.W. Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions. J. Clin. Invest. 94:1994;437-444
10. Sugiyama S., Okada Y., Sukhova G.K., Virmani R., Heinecke J.W. Libby, P. Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes. Am. J. Pathol. 158:2001;879-891
11. Baldus S., Eiserich J.P., Mani A., Castro L., Figueroa M., Chumley P., Ma W., Tousson A., White C.R., Bullard D.C., Brennan M.L., Lusis A.J., Moore K.P., Freeman B.A. Endothelial transcytosis of myeloperoxidase confers specificity to vascular ECM proteins as targets of tyrosine nitration. J. Clin. Invest. 108:2001;1759-1770
12. Eiserich J.P., Baldus S., Brennan M.L., Ma W., Zhang C., Tousson A., Castro L., Lusis A.J., Nauseef W.M., White C.R., Freeman B.A. Myeloperoxidase, a leukocyte-derived vascular NO oxidase. Science. 296:2002;2391-2394
13. Abu-Soud H.M., Hazen S.L. Nitric oxide is a physiological substrate for mammalian peroxidases. J. Biol. Chem. 275:2000;37524-37532
14. Baldus S., Eiserich J.P., Brennan M.L., Jackson R.M., Alexander C.B., Freeman B.A. Spatial mapping of pulmonary and vascular nitrotyrosine reveals the pivotal role of myeloperoxidase as a catalyst for tyrosine nitration in inflammatory diseases. Free Radic. Biol. Med. 33:2002;1010
15. Heitzer T., Yla-Herttuala S., Luoma J., Kurz S., Munzel T., Just H., Olschewski M., Drexler H. Cigarette smoking potentiates endothelial dysfunction of forearm resistance vessels in patients with hypercholesterolemia. Role of oxidized LDL. Circulation. 93:1996;1346-1353
16. Heitzer T., Just H., Munzel T. Antioxidant vitamin C improves endothelial dysfunction in chronic smokers. Circulation. 94:1996;6-9
17. Heitzer T., Ollmann I., Koke K., Meinertz T., Munzel T. Platelet glycoprotein IIb/IIIa receptor blockade improves vascular nitric oxide bioavailability in patients with coronary artery disease. Circulation. 108:2003;536-541
18. Jordan J.E., Zhao Z.Q., Vinten-Johansen J. The role of neutrophils in myocardial ischemia-reperfusion injury. Cardiovasc. Res. 43:1999;860-878
19. 2/halide system in human atherosclerotic lesions: colocalization of myeloperoxidase and hypochlorite-modified proteins. Eur. J. Biochem. 267:2000;4495-4503
20. Byun J., Henderson J.P., Mueller D.M., Heinecke J.W. 8-Nitro-2′- deoxyguanosine, a specific marker of oxidation by reactive nitrogen species, is generated by the myeloperoxidase/hydrogen peroxide/nitrite system of activated human phagocytes. Biochemistry. 38:1999;2590-2600
21. Hazen S.L., Zhang R., Shen Z., Wu W., Podrez E.A., MacPherson J.C., Schmitt D., Mitra S.N., Mukhopadhyay C., Chen Y., Cohen P.A., Hoff H.F., Abu-Soud H.M. Formation of nitric oxide-derived oxidants by myeloperoxidase in monocytes: pathways for monocyte-mediated protein nitration and lipid peroxidation in vivo. Circ. Res. 85:1999;950-958
22. Liu P., Xu B., Forman L.J., Carsia R., Hock C.E. L-NAME enhances microcirculatory congestion and cardiomyocyte apoptosis during myocardial ischemia-reperfusion in rats. Shock. 17:2002;185-192
23. Ozaki M., Kawashima S., Yamashita T., Hirase T., Ohashi Y., Inoue N., Hirata K., Yokoyama M. Overexpression of endothelial nitric oxide synthase attenuates cardiac hypertrophy induced by chronic isoproterenol infusion. Circ. J. 66:2002;851-856
24. Stangl V., Rodiger O., Frank T.M., Bohm M., Stangl K., Baumann G., Felix S.B. Influence of polymorphonuclear leukocytes and plasma on coronary vasomotion after ischemia. Ann. Thorac. Surg. 68:1999;442-446
25. Sheridan B.C., McIntyre R.C., Agrafojo J., Meldrum D.R., Meng X., Fullerton D.A. Neutrophil depletion attenuates endotoxin-induced dysfunction of cGMP-mediated pulmonary vasorelaxation. Am. J. Physiol. 271:1996;L820-L828
26. Eiserich J.P., Butler J., van der Vliet A., Cross C.E., Halliwell B. Nitric oxide rapidly scavenges tyrosine and tryptophan radicals. Biochem. J. 310(Pt 3):1995;745-749
27. Griendling K.K., Sorescu D., Ushio-Fukai M. NAD(P)H oxidase: role in cardiovascular biology and disease. Circ. Res. 86:2000;494-501
28. Naruko T., Ueda M., Haze K., van der Wal A.C., van der Loos C.M., Itoh A., Komatsu R., Ikura Y., Ogami M., Shimada Y., Ehara S., Yoshiyama M., Takeuchi K., Yoshikawa J., Becker A.E. Neutrophil infiltration of culprit lesions in acute coronary syndromes. Circulation. 106:2002;2894-2900
29. Ross R. Atherosclerosis - an inflammatory disease. N. Engl. J. Med. 340:1999;115-126
30. Zhang R., Brennan M.L., Fu X., Aviles R.J., Pearce G.L., Penn M.S., Topol E.J., Sprecher D.L., Hazen S.L. Association between myeloperoxidase levels and risk of coronary artery disease. JAMA. 286:2001;2136-2142
31. Buffon A., Biasucci L.M., Liuzzo G., D'Onofrio G., Crea F., Maseri A. Widespread coronary inflammation in unstable angina. N. Engl. J. Med. 347:2002;5-12
32. Shen K., DeLano F.A., Zweifach B.W., Schmid-Schonbein G.W. Circulating leukocyte counts, activation, and degranulation in Dahl hypertensive rats. Circ. Res. 76:1995;276-283
33. Baldus S., Heeschen C., Meinertz T., Zeiher A.M., Eiserich J.P., Munzel T., Simoons M.L., Hamm C.W. Myeloperoxidase serum levels predict risk in patients with acute coronary syndromes. Circulation. 108(12):2003;1440-1445
34. Brennan M.L., Penn M.S., Van Lente F., Nambi V., Shishehbor M.H., Aviles R.J., Goormastic M., Pepoy M.L., McErlean E.S., Topol E.J., Nissen S.E., Hazen S.L. Prognostic value of myeloperoxidase in patients with chest pain. N. Engl. J. Med. 349:2003;1595-1604