Neutrophil depletion attenuates endotoxin-induced dysfunction of cGMP- mediated pulmonary vasorelaxation

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 271, Issue 5 15-5, 1996, Pages

  Sheridan, Brett C ^a   Mcintyre, Robert C ^a   Agrafojo, Jeanette ^a   Meldrum, Daniel R ^a   Meng, Xianzhong ^a   Fullerton, David A ^a,b  

^a UNIVERSITY OF COLORADO   (United States)

^b NORTHWESTERN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

acute lung injury; endothelium; neutropenia; smooth muscle

Indexed keywords

ACETYLCHOLINE; CALCIMYCIN; CYCLIC GMP; GRANULOCYTE ANTIBODY; MYELOPEROXIDASE; NITROPRUSSIDE SODIUM; PHENYLEPHRINE; SALMONELLA ENDOTOXIN; VINBLASTINE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; LUNG INJURY; LUNG WEIGHT; MALE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; RAT; VASCULAR ENDOTHELIUM; VASODILATATION;

EID: 0029951289     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1996.271.5.l820     Document Type: Article

References (22)

1. Anderson, B. O., E. E. Moore, F. A. Moore, J. A. Leff, L. S. Terada, A. H. Harken, and J. E. Repine. Hypovolemic shock promotes neutrophil sequestration in lungs by a xanthine oxidase-related mechanism. J. Appl. Physiol. 71: 1862-1865, 1991.
2. Chang, S. W., C. O. Fedderson, P. M. Henson, and N. F. Voelkel. Platelet activating factor mediates hemodynamic changes and lung injury in endotoxin treated rats. J. Clin. Invest. 79: 1498-1509, 1987.
3. Cirelli, R. A., L. A. Carey, J. K. Fisher, D. L. Rosolia, T. H. Elsasser, T. J. Caperna, M. H. Gee, and K. H. Albertine. Endotoxin infusion in anesthetized sheep is associated with intrapulmonary sequestretion of leukocytes that immunohistochemically express tumor necrosis factor-α. J. Leukocyte Biol. 57: 820-826, 1995.
4. Dinh-Xuan, A. T., T. W. Higgenbottom, C. Clelland, J. Epke-Zaba, G. Cremona, A. Y. Butt, S. R. Large, F. C. Wells, and J. Wallwork. Impairment of endothelium-dependent pulmonary artery relaxation in chronic obstructive lung disease. N. Engl. J. Med. 324: 1539-1547, 1991.
5. Fullerton D. A., R. C. McIntyre, A. R. Hahn, J. Agrafojo, K. Koike, A. Banerjee, and A. H. Harken. Dysfunction of cGMP-mediated pulmonary vasorelaxation in endotoxin-induced acute lung injury. Am. J. Physiol. 268 (Lung Cell. Mol. Physiol. 12): L1029-L1035, 1995.
6. Gwitner, G. H., A. Knolblauch, A. L. Smith, H. Sies, and N. F. Adkinson. Oxidant- and lipid-induced pulmonary vasoconstriction mediated by arachidonic acid metabolites. J. Appl. Physiol. 55: 949-954, 1983.
7. Harlan J. M., L. A. Harker, M. A. Riedy, C. M. Gajdusek, A. M. Schwartz, and G. E. Striker. Lipopolysaccharide-mediated bovine pulmonary endothelial cell injury in vitro. Lab. Invest. 48: 269-274, 1983.
8. Haslett C., G. S. Worthen, P. C. Giclas, D. C. Morrison, J. E. Henson, and P. M. Henson. The pulmonary vascular sequestration of neutrophils in endotoxemia is initiated by an effect of endotoxin on the neutrophil in the rabbit. Am. Rev. Respir. Dis. 136: 9-18, 1987.
9. Heflin, A. C., and K. L. Brigham. Prevention by granulocyte depletion of increased vascular permeability of sheep lung following endotoxemia. J. Clin. Invest. 68: 1253-1260, 1981.
10. Hinson, J. M., Jr., A. A. Hutchinson, M. L. Ogletree, K. L. Brigham, and J. Snapper. Effect of granulocyte depletion on altered lung mechanics after endotoxemia in sheep. J. Appl. Physiol. 55: 92-99, 1983.
11. Huttemeier, P. C., W. D., Watkins, M. B. Peterson, and W. M. Zapol. Acute pulmonary hypertension and lung thromboxane release after endotoxin infusion in normal and leukopenic sheep. Circ. Res. 50: 688-694, 1982.
12. Ignarro, L. J. Biosynthesis and metabolism of endothelium-derived nitric oxide. Annu. Rev. Pharmacol. Toxicol. 30: 535-560, 1990.
13. Meyrick B. O., and K. L. Brigham. Acute effects of Escherichia coli endotoxin on the pulmonary microcirculation of anesthestized sheep. Lab. Invest. 48: 458-470, 1983.
14. Sibbald, W. J., N. A. Patterson, R. J. Holliday, R. A. Anderson T. R. Lobb, and J. H. Duff. Pulmonary hypertension in sepsis: measurement by the pulmonary arterial-pulmonary wedge pressure gradient and the influence of active and passive factors. Chest 73: 583-591, 1978.
15. Spath J.A., P. J. Sloane, M. H. Gee, and K. H. Albertine. Loss of endothelium-dependent vasodilation in the pulmonary vessels of sheep after prolonged endotoxin. J. Appl. Physiol. 76: 361-369, 1994.
16. Tate, R. M., and J. E. Repine. Neutrophils and the adult respiratory distress syndrome. Am. Rev. Respir. Dis. 128: 552-559, 1983.
17. Tate R. M., K. M. Vanbenthuysen, D. M. Shasby, I. F. McMurtry, and J. E. Repine. Oxygen radical mediated permeability edema and vasoconstriction in isolated perfused rabbit lungs. Am. Rev. Respir. Dis. 126: 802-806, 1982.
18. Vane J. R., E. E. Anggard, and R. M. Botting. Regulatory functions of the vascular endothelium. N. Engl. J. Med. 323: 27-36, 1990.
19. Verani, J., M. J. Bendelow, D. E. Sealey, S. L. Kunlel, D. E. Gannon, U. S. Ryan, and P. A. Ward. Tumor necrosis factor enhances susceptibility of vascular endothelial cells to neutrophil-mediated killing. Lab. Invest. 59: 292-295, 1988.
20. Walkins, D. W., P. C. Huttemeier, D. Kong, M. B. Peterson. Thromboxane and pulmonary hypertension following E. coli endotoxin infusion in sheep: effect of an imidazole derivative. Prostaglandins 23: 273-281, 1982.
21. Worthen, G. S., C. Haslett, A. J. Rees, R. S. Gumbay, J. E. Hensen, and P. M. Hensen. Neutrophil-mediated pulmonary vascular injury: synergistic effect of trace amounts of lipopolysaccharide and neutrophil stimuli on vascular permeability and neutrophil sequestration in the lung. Am. Rev. Respir. Dis. 136. 19-28, 1987.
22. Zapol, W. M., and M. T. Snider. Pulmonary hypertension in severe acute respiratory failure. N. Engl. J. Med. 296: 476-480, 1977.