메뉴 건너뛰기




Volumn , Issue 138, 2003, Pages 45-52

Glucagon-like peptide 1 (GLP-1): A promising approach and a novel treatment for patients with type 2 diabetes

Author keywords

[No Author keywords available]

Indexed keywords

ACARBOSE; ADRENALIN; ANTIDIABETIC AGENT; CJC 1131; DIPEPTIDYL PEPTIDASE IV; DIPEPTIDYL PEPTIDASE IV INHIBITOR; ENZYME INHIBITOR; EXENDIN 4; GLUCAGON; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 1 [7-36] AMIDE; GLUCAGON LIKE PEPTIDE 1 DERIVATIVE; GROWTH HORMONE; HEMOGLOBIN A1C; HYDROCORTISONE; INSULIN; LIRAGLUTIDE; METFORMIN; NORADRENALIN; SULFONYLUREA DERIVATIVE; UNCLASSIFIED DRUG;

EID: 4043048804     PISSN: 1368504X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (2)

References (43)
  • 1
    • 0026786570 scopus 로고
    • Gut hormones and diabetes mellitus
    • Creutzfeldt W, Nauck M. Gut hormones and diabetes mellitus. Diabetes/Metab Rev 1992; 8: 149-177.
    • (1992) Diabetes/Metab Rev , vol.8 , pp. 149-177
    • Creutzfeldt, W.1    Nauck, M.2
  • 2
    • 0027391607 scopus 로고
    • Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus
    • Nauck MA, Heimesaat MM, Ørskov C et al. Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus. J Clin Invest 1993; 91: 301-307.
    • (1993) J Clin Invest , vol.91 , pp. 301-307
    • Nauck, M.A.1    Heimesaat, M.M.2    Ørskov, C.3
  • 4
    • 0030613750 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 and its potential in the treatment of non-insulin-dependent diabetes mellitus
    • Nauck MA, Hoist JJ, Willms B. Glucagon-like peptide 1 and its potential in the treatment of non-insulin-dependent diabetes mellitus. Horm Metab Res 1997; 29: 411-416.
    • (1997) Horm Metab Res , vol.29 , pp. 411-416
    • Nauck, M.A.1    Hoist, J.J.2    Willms, B.3
  • 5
    • 0033175006 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 (GLP-1): An intestinal hormone, signalling nutritional abundance, with an unusual therapeutic potential
    • Hoist JJ. Glucagon-like peptide 1 (GLP-1): an intestinal hormone, signalling nutritional abundance, with an unusual therapeutic potential. Trends Endocrinol Metab 1999; 10: 229-235.
    • (1999) Trends Endocrinol Metab , vol.10 , pp. 229-235
    • Hoist, J.J.1
  • 6
    • 0023638829 scopus 로고
    • Glucagon-like peptide-1 [7-36]: A physiological incretin in man
    • Kreymann B, Williams G, Ghatei MA, Bloom SR. Glucagon-like peptide-1 [7-36]: a physiological incretin in man. Lancet 1987; 2: 1300-1304.
    • (1987) Lancet , vol.2 , pp. 1300-1304
    • Kreymann, B.1    Williams, G.2    Ghatei, M.A.3    Bloom, S.R.4
  • 7
    • 0027419106 scopus 로고
    • Additive insulinotropic effects of exogenous synthetic human gastric inhibitory polypeptide and glucagon-like peptide-1-(7-36) amide infused at near-physiological insulinotropic hormone and glucose concentrations
    • Nauck MA, Bartels E, Ørskov C, Ebert R, Creutzfeldt W. Additive insulinotropic effects of exogenous synthetic human gastric inhibitory polypeptide and glucagon-like peptide-1-(7-36) amide infused at near-physiological insulinotropic hormone and glucose concentrations. J Clin Endocrinol Metab 1993; 76: 912-917.
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 912-917
    • Nauck, M.A.1    Bartels, E.2    Ørskov, C.3    Ebert, R.4    Creutzfeldt, W.5
  • 8
    • 0036959991 scopus 로고    scopus 로고
    • Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemic clamp experiments in healthy volunteers
    • Nauck MA, Heimesaat MM, Behle K et al. Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemic clamp experiments in healthy volunteers. J Clin Endocrinol Metab 2002; 87: 1239-1246.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 1239-1246
    • Nauck, M.A.1    Heimesaat, M.M.2    Behle, K.3
  • 9
    • 0030667056 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans
    • Nauck MA, Niedereichholz U, Ettler R et al. Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans. Am J Physiol 1997; 273: E981-988.
    • (1997) Am J Physiol , vol.273
    • Nauck, M.A.1    Niedereichholz, U.2    Ettler, R.3
  • 10
    • 0035115950 scopus 로고    scopus 로고
    • Glucagon-like peptide-1. Gastrointestinal function and possible mechanism of action
    • Wettergren A. Glucagon-like peptide-1. Gastrointestinal function and possible mechanism of action. Dan Med Bull 2001; 48: 19-28.
    • (2001) Dan Med Bull , vol.48 , pp. 19-28
    • Wettergren, A.1
  • 11
    • 0032005005 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 promotes satiety and suppresses energy intake in humans
    • Flint A, Raben A, Astrup A, Hoist JJ. Glucagon-like peptide-1 promotes satiety and suppresses energy intake in humans. J Clin Invest 1998; 101: 515-520.
    • (1998) J Clin Invest , vol.101 , pp. 515-520
    • Flint, A.1    Raben, A.2    Astrup, A.3    Hoist, J.J.4
  • 12
    • 0032966882 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 promotes satiety and reduces food intake in patients with diabetes mellitus type 2
    • Gutzwiller JP, Drewe J, Goke B et al. Glucagon-like peptide-1 promotes satiety and reduces food intake in patients with diabetes mellitus type 2. Am J Physiol 1999; 276: R1541-1544.
    • (1999) Am J Physiol , vol.276
    • Gutzwiller, J.P.1    Drewe, J.2    Goke, B.3
  • 13
    • 0034032317 scopus 로고    scopus 로고
    • Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas
    • Stoffers DA, Kieffer TJ, Hussain MA et al. Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas. Diabetes 2000; 49: 741-748.
    • (2000) Diabetes , vol.49 , pp. 741-748
    • Stoffers, D.A.1    Kieffer, T.J.2    Hussain, M.A.3
  • 14
    • 0035084164 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 induces differentiation of islet duodenal homeobox-1-positive pancreatic ductal cells into insulin-secreting cells
    • Hui H, Wright C, Perfetti R. Glucagon-like peptide 1 induces differentiation of islet duodenal homeobox-1-positive pancreatic ductal cells into insulin-secreting cells. Diabetes 2001; 50: 785-796.
    • (2001) Diabetes , vol.50 , pp. 785-796
    • Hui, H.1    Wright, C.2    Perfetti, R.3
  • 15
    • 0023916553 scopus 로고
    • Abnormal patterns of insulin secretion in non-insulin-dependent diabetes mellitus
    • Polonsky KS, Given BD, Hirsch LJ et al. Abnormal patterns of insulin secretion in non-insulin-dependent diabetes mellitus. N Engl J Med 1988; 318: 1231-1239.
    • (1988) N Engl J Med , vol.318 , pp. 1231-1239
    • Polonsky, K.S.1    Given, B.D.2    Hirsch, L.J.3
  • 16
    • 4043113025 scopus 로고
    • Abnormal glucagon secretion in type 2 (noninsulin-dependent) diabetes mellitus: Causes and consequences
    • Creutzfeldt W, Lefèbvre P, editors. Berlin, Heidelberg: Springer Verlag
    • Gerich JE. Abnormal glucagon secretion in type 2 (noninsulin-dependent) diabetes mellitus: Causes and consequences. In: Creutzfeldt W, Lefèbvre P, editors. Diabetes mellitus: Pathophysiology and therapy. Berlin, Heidelberg: Springer Verlag; 1989: pp. 127-133.
    • (1989) Diabetes Mellitus: Pathophysiology and Therapy , pp. 127-133
    • Gerich, J.E.1
  • 17
    • 0028917432 scopus 로고
    • Weight gain as a risk factor for clinical diabetes mellitus in women
    • Colditz GA, Willett WC, Rotnitzky A, Manson JE. Weight gain as a risk factor for clinical diabetes mellitus in women. Ann Intern Med 1995; 122: 481-486.
    • (1995) Ann Intern Med , vol.122 , pp. 481-486
    • Colditz, G.A.1    Willett, W.C.2    Rotnitzky, A.3    Manson, J.E.4
  • 18
    • 4043149581 scopus 로고
    • Islet cell populations in obese subjects and Type 2 (non-insulin- dependent) diabetic patients
    • Rahier JRD, Ibrahim M, Channaoui K. Islet cell populations in obese subjects and Type 2 (non-insulin-dependent) diabetic patients (abstract). Diabetologia 1989; 32 (Suppl. 1): 532 A.
    • (1989) Diabetologia , vol.32 , Issue.SUPPL. 1
    • Rahier, J.R.D.1    Ibrahim, M.2    Channaoui, K.3
  • 19
    • 0037219411 scopus 로고    scopus 로고
    • Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes
    • Butler AE, Janson J, Bonner-Weir S et al. Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes. Diabetes 2003; 52: 102-110.
    • (2003) Diabetes , vol.52 , pp. 102-110
    • Butler, A.E.1    Janson, J.2    Bonner-Weir, S.3
  • 21
    • 0037045845 scopus 로고    scopus 로고
    • Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: A parallel-group study
    • Zander M, Madsbad S, Madsen JL, Hoist JJ. Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: a parallel-group study. Lancet 2002; 359: 824-830.
    • (2002) Lancet , vol.359 , pp. 824-830
    • Zander, M.1    Madsbad, S.2    Madsen, J.L.3    Hoist, J.J.4
  • 22
    • 0027248866 scopus 로고
    • Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients
    • Nauck MA, Kleine N, Ørskov C et al. Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients. Diabetologia 1993; 36: 741-744.
    • (1993) Diabetologia , vol.36 , pp. 741-744
    • Nauck, M.A.1    Kleine, N.2    Ørskov, C.3
  • 23
    • 0030068620 scopus 로고    scopus 로고
    • Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: Effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients
    • Willms B, Werner J, Holst JJ et al. Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients. J Clin Endocrinol Metab 1996; 81: 327-332.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 327-332
    • Willms, B.1    Werner, J.2    Holst, J.J.3
  • 24
    • 0029954211 scopus 로고    scopus 로고
    • Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide 1(7-36) amide in type 1 diabetic patients
    • Creutzfeldt WO, Kleine N, Willms B et al. Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide 1(7-36) amide in type 1 diabetic patients. Diabetes Care 1996; 19: 580-586.
    • (1996) Diabetes Care , vol.19 , pp. 580-586
    • Creutzfeldt, W.O.1    Kleine, N.2    Willms, B.3
  • 25
    • 0031033531 scopus 로고    scopus 로고
    • Near-normalization of diurnal glucose concentrations by continuous administration of glucagon-like peptide 1 (GLP-1) in subjects with NIDDM
    • Rachman J, Gribble FM, Levy JC, Turner RC. Near-normalization of diurnal glucose concentrations by continuous administration of glucagon-like peptide 1 (GLP-1) in subjects with NIDDM. Diabetologia 1997; 40: 205-211.
    • (1997) Diabetologia , vol.40 , pp. 205-211
    • Rachman, J.1    Gribble, F.M.2    Levy, J.C.3    Turner, R.C.4
  • 26
    • 0035432607 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 infusion must be maintained for 24 h/day to obtain acceptable glycemia in type 2 diabetic patients who are poorly controlled on sulphonylurea treatment
    • Larsen J, Hylleberg B, Ng K, Damsbo P. Glucagon-like peptide-1 infusion must be maintained for 24 h/day to obtain acceptable glycemia in type 2 diabetic patients who are poorly controlled on sulphonylurea treatment. Diabetes Care 2001; 24: 1416-1421.
    • (2001) Diabetes Care , vol.24 , pp. 1416-1421
    • Larsen, J.1    Hylleberg, B.2    Ng, K.3    Damsbo, P.4
  • 27
    • 0029074964 scopus 로고
    • Pharmacokinetic, insulinotropic, and glucagonostatic static properties of GLP-1 [7-36 amide] after subcutaneous injection in healthy volunteers. Dose-response-relationships
    • Ritzel R, Ørskov C, Hoist JJ, Nauck MA. Pharmacokinetic, insulinotropic, and glucagonostatic static properties of GLP-1 [7-36 amide] after subcutaneous injection in healthy volunteers. Dose-response-relationships. Diabetologia 1995; 38: 720-725.
    • (1995) Diabetologia , vol.38 , pp. 720-725
    • Ritzel, R.1    Ørskov, C.2    Hoist, J.J.3    Nauck, M.A.4
  • 28
    • 0028803336 scopus 로고
    • Both subcutaneously and intravenously administered glucagon-like peptide 1 are rapidly degraded from the NH2-terminus in type 2-diabetic patients and in healthy subjects
    • Deacon CF, Nauck MA, Toft-Nielsen M et al. Both subcutaneously and intravenously administered glucagon-like peptide 1 are rapidly degraded from the NH2-terminus in type 2-diabetic patients and in healthy subjects. Diabetes 1995; 44: 1126-1131.
    • (1995) Diabetes , vol.44 , pp. 1126-1131
    • Deacon, C.F.1    Nauck, M.A.2    Toft-Nielsen, M.3
  • 29
    • 0031740718 scopus 로고    scopus 로고
    • Normalization of fasting glycaemia by intravenous GLP-1 ([7-36 amide] or [7-37]) in Type 2-diabetic patients
    • Nauck MA, Weber I, Bach I et al. Normalization of fasting glycaemia by intravenous GLP-1 ([7-36 amide] or [7-37]) in Type 2-diabetic patients. Diabetic Med 1998; 15: 937-945.
    • (1998) Diabetic Med , vol.15 , pp. 937-945
    • Nauck, M.A.1    Weber, I.2    Bach, I.3
  • 30
    • 0029907680 scopus 로고    scopus 로고
    • Effects of subcutaneous glucagon-like peptide 1 (GLP-1 [7-36 amide]) in patients with NIDDM
    • Nauck MA, Wollschläger D, Werner J et al. Effects of subcutaneous glucagon-like peptide 1 (GLP-1 [7-36 amide]) in patients with NIDDM. Diabetologia 1996; 39: 1546-1553.
    • (1996) Diabetologia , vol.39 , pp. 1546-1553
    • Nauck, M.A.1    Wollschläger, D.2    Werner, J.3
  • 31
    • 0001095690 scopus 로고    scopus 로고
    • Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients
    • Vilsboll T, Krarup T, Deacon CF, Madsbad S, Hoist JJ. Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients. Diabetes 2001; 50: 609-613.
    • (2001) Diabetes , vol.50 , pp. 609-613
    • Vilsboll, T.1    Krarup, T.2    Deacon, C.F.3    Madsbad, S.4    Hoist, J.J.5
  • 32
    • 0034880655 scopus 로고    scopus 로고
    • Determinants of the impaired secretion of glucagon-like peptide-1 in type 2 diabetic patients
    • Toft-Nielsen MB, Damholt MB, Madsbad S et al. Determinants of the impaired secretion of glucagon-like peptide-1 in type 2 diabetic patients. J Clin Endocrinol Metab 2001; 86: 3717-3723.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 3717-3723
    • Toft-Nielsen, M.B.1    Damholt, M.B.2    Madsbad, S.3
  • 33
    • 0036066641 scopus 로고    scopus 로고
    • Bedtime administration of NN2211, a long-acting GLP-1 derivative, substantially reduces fasting and postprandial glycemia in type 2 diabetes
    • Juhl CB, Hollingdal M, Sturis J et al. Bedtime administration of NN2211, a long-acting GLP-1 derivative, substantially reduces fasting and postprandial glycemia in type 2 diabetes. Diabetes 2002; 51: 424-429.
    • (2002) Diabetes , vol.51 , pp. 424-429
    • Juhl, C.B.1    Hollingdal, M.2    Sturis, J.3
  • 34
    • 0038527035 scopus 로고    scopus 로고
    • The long-acting GLP-1 derivative, NN2211, a new agent for the treatment of type 2 diabetes
    • Matthews D, Madsbad S, Schmilz O, Langendorf KW, Jakobsen G. The long-acting GLP-1 derivative, NN2211, a new agent for the treatment of type 2 diabetes (abstract). Diabetes 2002; 51 (Suppl. 2): A 84.
    • (2002) Diabetes , vol.51 , Issue.SUPPL. 2
    • Matthews, D.1    Madsbad, S.2    Schmilz, O.3    Langendorf, K.W.4    Jakobsen, G.5
  • 35
    • 0012980860 scopus 로고    scopus 로고
    • The long-acting GLP-1 agonist CJC 1131 exhibits high potency and extended pharmacokinetics in vivo
    • Bridon DP, Thibaudeau K, L'Archeveque BP et al. The long-acting GLP-1 agonist CJC 1131 exhibits high potency and extended pharmacokinetics in vivo (abstract). Diabetes 2002; 51 (Suppl. 2): A 93.
    • (2002) Diabetes , vol.51 , Issue.SUPPL. 2
    • Bridon, D.P.1    Thibaudeau, K.2    L'Archeveque, B.P.3
  • 36
    • 0010795476 scopus 로고    scopus 로고
    • Development and characterization of long-acting degradation resistant GLP-1-DAC compounds for the treatment of type 2 diabetes
    • Thibaudeau K, Smith DC, Jette L et al. Development and characterization of long-acting degradation resistant GLP-1-DAC compounds for the treatment of type 2 diabetes (abstract). Diabetes 2002; 50 (Suppl. 2): A 116.
    • (2002) Diabetes , vol.50 , Issue.SUPPL. 2
    • Thibaudeau, K.1    Smith, D.C.2    Jette, L.3
  • 37
    • 0027184119 scopus 로고
    • Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells
    • Göke R, Fehmann HC, Linn T et al. Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells. J Biol Chem 1993; 268: 19650-19655.
    • (1993) J Biol Chem , vol.268 , pp. 19650-19655
    • Göke, R.1    Fehmann, H.C.2    Linn, T.3
  • 38
    • 0027425034 scopus 로고
    • Cloning and functional expression of the human islet GLP-1 receptor. Demonstration that exendin-4 is an agonist and exendin-(9-39) an antagonist of the receptor
    • Thorens B, Porret A, Buhler L et al. Cloning and functional expression of the human islet GLP-1 receptor. Demonstration that exendin-4 is an agonist and exendin-(9-39) an antagonist of the receptor. Diabetes 1993; 42: 1678-1682.
    • (1993) Diabetes , vol.42 , pp. 1678-1682
    • Thorens, B.1    Porret, A.2    Buhler, L.3
  • 39
    • 0038584690 scopus 로고    scopus 로고
    • Dose-response for inhibition of glucagon secretion and gastric emptying by synthetic exendin-4 (AC2993) in subjects with Type 2 diabetes
    • Kolterman O, Gottlieb A, Prickett K, Gaines E, Young A. Dose-response for inhibition of glucagon secretion and gastric emptying by synthetic exendin-4 (AC2993) in subjects with Type 2 diabetes (abstract). Diabetes 2000; 49 (Suppl. 1): A 114.
    • (2000) Diabetes , vol.49 , Issue.SUPPL. 1
    • Kolterman, O.1    Gottlieb, A.2    Prickett, K.3    Gaines, E.4    Young, A.5
  • 40
    • 0012306247 scopus 로고    scopus 로고
    • AC 2993 (synthetic exendin-4) added to existing metformin (MET) and/or sulfonylurea (SFU) treatment improved glycemic control in patients with type 2 diabetes (DM2) durign 28 days of treatment
    • Fineman MS, Bicsak T, Shen L et al. AC 2993 (synthetic exendin-4) added to existing metformin (MET) and/or sulfonylurea (SFU) treatment improved glycemic control in patients with type 2 diabetes (DM2) durign 28 days of treatment (abstract). Diabetes 2002; 51 (Suppl. 2): A 85.
    • (2002) Diabetes , vol.51 , Issue.SUPPL. 2
    • Fineman, M.S.1    Bicsak, T.2    Shen, L.3
  • 41
    • 0031916924 scopus 로고    scopus 로고
    • Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig
    • Deacon CF, Highes TE, Holst JJ. Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig. Diabetes 1998; 47: 764-769.
    • (1998) Diabetes , vol.47 , pp. 764-769
    • Deacon, C.F.1    Highes, T.E.2    Holst, J.J.3
  • 42
    • 0035403058 scopus 로고    scopus 로고
    • Dipeptidyl peptidase IV inhibition reduces the degradation and clearance of GIP and potentiates its insulinotropic and antihyperglycemic effects in anesthetized pigs
    • Deacon CF, Danielsen P, Klarskov L, Olesen M, Holst JJ. Dipeptidyl peptidase IV inhibition reduces the degradation and clearance of GIP and potentiates its insulinotropic and antihyperglycemic effects in anesthetized pigs. Diabetes 2001; 50: 1588-1597.
    • (2001) Diabetes , vol.50 , pp. 1588-1597
    • Deacon, C.F.1    Danielsen, P.2    Klarskov, L.3    Olesen, M.4    Holst, J.J.5
  • 43
    • 0036583164 scopus 로고    scopus 로고
    • Inhibition of dipeptidyl peptidase IV improves metabolic control over a 4-week study period in type 2 diabetes
    • Åhren B, Simonsson E, Larsson H et al. Inhibition of dipeptidyl peptidase IV improves metabolic control over a 4-week study period in type 2 diabetes. Diabetes Care 2002; 25: 869-875.
    • (2002) Diabetes Care , vol.25 , pp. 869-875
    • Åhren, B.1    Simonsson, E.2    Larsson, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.