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Volumn 147, Issue 2, 2008, Pages 216-222

The functional polymorphism of the hemoglobin-binding protein haptoglobin influences susceptibility to idiopathic Parkinson's disease

Author keywords

Haptoglobin; Idiopathic Parkinson's disease; Iron; Polymorphism; Smoking status

Indexed keywords

HAPTOGLOBIN;

EID: 40349116885     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.30593     Document Type: Article
Times cited : (29)

References (56)
  • 1
    • 0034649437 scopus 로고    scopus 로고
    • Parkinson's disease and Parkinsonism in a longitudinal study: Two‐fold higher incidence in men. ILSA Working Group. Italian Longitudinal Study on Aging
    • Baldereschi M, Di Carlo A, Rocca WA, Vanni P, Maggi S, Perissinotto E, Grigoletto F, Amaducci L, Inzitari D. 2000. Parkinson's disease and Parkinsonism in a longitudinal study: Two‐fold higher incidence in men. ILSA Working Group. Italian Longitudinal Study on Aging. Neurology 55: 1358–1363.
    • (2000) Neurology , vol.55 , pp. 1358-1363
    • Baldereschi, M1    Di Carlo, A2    Rocca, WA3    Vanni, P4    Maggi, S5    Perissinotto, E6    Grigoletto, F7    Amaducci, L8    Inzitari, D9
  • 2
    • 0025644370 scopus 로고
    • Heterozygosity effects in studies of genetic markers and disease
    • Beckman L, Fröhlander N. 1990. Heterozygosity effects in studies of genetic markers and disease. Hum Hered 40: 322–329.
    • (1990) Hum Hered , vol.40 , pp. 322-329
    • Beckman, L1    Fröhlander, N2
  • 3
    • 0025824668 scopus 로고
    • Intranigral iron injection induces behavioural and biochemical “parkinsonism” in rats
    • Ben‐Shachar D, Youdim MB. 1991. Intranigral iron injection induces behavioural and biochemical “parkinsonism” in rats. J Neurochem 57: 2133–2135.
    • (1991) J Neurochem , vol.57 , pp. 2133-2135
    • Ben‐Shachar, D1    Youdim, MB2
  • 4
    • 17144460129 scopus 로고
    • Haptoglobin: The evolutionary product of duplication, unequal crossing over, and point mutation
    • Bowman BH, Kurosky A. 1982. Haptoglobin: The evolutionary product of duplication, unequal crossing over, and point mutation. Adv Hum Genet 12: 189–261, 453–454.
    • (1982) Adv Hum Genet , vol.12 , pp. 189-261
    • Bowman, BH1    Kurosky, A2
  • 5
    • 0021760449 scopus 로고
    • Evolution of haptoglobin: Comparison of complementary DNA encoding Hp alpha 1S and Hp alpha 2FS
    • Brune JL, Yang F, Barnett DR, Bowman BH. 1984. Evolution of haptoglobin: Comparison of complementary DNA encoding Hp alpha 1S and Hp alpha 2FS. Nucleic Acids Res 12: 4531–4538.
    • (1984) Nucleic Acids Res , vol.12 , pp. 4531-4538
    • Brune, JL1    Yang, F2    Barnett, DR3    Bowman, BH4
  • 6
    • 34748903283 scopus 로고    scopus 로고
    • Association of APOE with Parkinson disease age‐at‐onset in women
    • Buchanan DD, Silburn PA, Prince JA, Mellick GD. 2007. Association of APOE with Parkinson disease age‐at‐onset in women. Neurosci Lett 411: 185–188.
    • (2007) Neurosci Lett , vol.411 , pp. 185-188
    • Buchanan, DD1    Silburn, PA2    Prince, JA3    Mellick, GD4
  • 7
    • 0031842608 scopus 로고    scopus 로고
    • A genetic polymorphism of MAO‐B modifies the association of cigarette smoking and Parkinson's disease
    • Checkoway H, Franklin GM, Costa‐Mallen P, Smith‐Weller T, Dilley J, Swanson PD, Costa LG. 1998. A genetic polymorphism of MAO‐B modifies the association of cigarette smoking and Parkinson's disease. Neurology 50: 1458–1461.
    • (1998) Neurology , vol.50 , pp. 1458-1461
    • Checkoway, H1    Franklin, GM2    Costa‐Mallen, P3    Smith‐Weller, T4    Dilley, J5    Swanson, PD6    Costa, LG7
  • 8
    • 0027399278 scopus 로고
    • Identification of haptoglobin as an angiogenic factor in sera from patients with systemic vasculitis
    • Cid MC, Derrick SG, Hoffman GS, Auerbach R, Fauci AS, Kleinman HK. 1993. Identification of haptoglobin as an angiogenic factor in sera from patients with systemic vasculitis. J Clin Invest 91: 977–985.
    • (1993) J Clin Invest , vol.91 , pp. 977-985
    • Cid, MC1    Derrick, SG2    Hoffman, GS3    Auerbach, R4    Fauci, AS5    Kleinman, HK6
  • 9
    • 0033804169 scopus 로고    scopus 로고
    • Molecular heterosis: A review
    • Comings DE, MacMurray JP. 2000. Molecular heterosis: A review. Mol Genet Metab 71: 19–31.
    • (2000) Mol Genet Metab , vol.71 , pp. 19-31
    • Comings, DE1    MacMurray, JP2
  • 11
    • 0023638828 scopus 로고
    • Increased nigral iron content in post‐mortem parkinsonian brain
    • Dexter DT, Wells FR, Agid F, Agid Y, Lees AJ, Jenner P, Marsden CD. 1987. Increased nigral iron content in post‐mortem parkinsonian brain. Lancet 2: 1219–1220.
    • (1987) Lancet , vol.2 , pp. 1219-1220
    • Dexter, DT1    Wells, FR2    Agid, F3    Agid, Y4    Lees, AJ5    Jenner, P6    Marsden, CD7
  • 12
    • 0014240538 scopus 로고
    • Studies in Parkinson's disease including X‐ray fluorescent spectroscopy of formalin‐fixed tissues
    • Earle KM. 1968. Studies in Parkinson's disease including X‐ray fluorescent spectroscopy of formalin‐fixed tissues. J Neuropathol Exp Neurol 27: 1–4.
    • (1968) J Neuropathol Exp Neurol , vol.27 , pp. 1-4
    • Earle, KM1
  • 13
    • 0024811603 scopus 로고
    • Haptoglobin groups in acute myocardial infarction
    • Fröhlander N, Johnsson O. 1989. Haptoglobin groups in acute myocardial infarction. Hum Hered 39: 345–350.
    • (1989) Hum Hered , vol.39 , pp. 345-350
    • Fröhlander, N1    Johnsson, O2
  • 14
    • 0024348133 scopus 로고
    • Association between haptoglobin groups and hereditary predisposition for bronchial asthma
    • Fröhlander N, Stjernberg N. 1989. Association between haptoglobin groups and hereditary predisposition for bronchial asthma. Hum Hered 39: 7–11.
    • (1989) Hum Hered , vol.39 , pp. 7-11
    • Fröhlander, N1    Stjernberg, N2
  • 15
    • 0028000825 scopus 로고
    • Altered brain metabolism of iron as a cause of neurodegenerative dieases?
    • Gerlach M, Ben‐Shachar D, Riederer P, Youdim MBH. 1994. Altered brain metabolism of iron as a cause of neurodegenerative dieases? J Neurochem 63: 793–807.
    • (1994) J Neurochem , vol.63 , pp. 793-807
    • Gerlach, M1    Ben‐Shachar, D2    Riederer, P3    Youdim, MBH4
  • 16
    • 11144353557 scopus 로고    scopus 로고
    • The relevance of iron in the pathogenesis of Parkinson's disease
    • Götz ME, Double K, Gerlach M, Youdim MBH, Riederer P. 2004. The relevance of iron in the pathogenesis of Parkinson's disease. Ann N Y Acad Sci 1012: 193–208.
    • (2004) Ann N Y Acad Sci , vol.1012 , pp. 193-208
    • Götz, ME1    Double, K2    Gerlach, M3    Youdim, MBH4    Riederer, P5
  • 17
    • 0024427198 scopus 로고
    • A simple and efficient non‐organic procedure for the isolation of genomic DNA from blood
    • Grimberg J, Nawoschik S, Belluscio L, McKee R, Turck A, Eisenberg A. 1989. A simple and efficient non‐organic procedure for the isolation of genomic DNA from blood. Nucleic Acids Res 17: 8390.
    • (1989) Nucleic Acids Res , vol.17 , pp. 8390
    • Grimberg, J1    Nawoschik, S2    Belluscio, L3    McKee, R4    Turck, A5    Eisenberg, A6
  • 18
    • 0034796353 scopus 로고    scopus 로고
    • Role of free radicals in the neurodegenerative diseases: Therapeutic implications for antioxidant treatment
    • Halliwell B. 2001. Role of free radicals in the neurodegenerative diseases: Therapeutic implications for antioxidant treatment. Drugs Aging 18: 685–716.
    • (2001) Drugs Aging , vol.18 , pp. 685-716
    • Halliwell, B1
  • 19
    • 0019467841 scopus 로고
    • Haptoglobin. A novel mode of biosynthesis of a liver secretory glycoprotein
    • Haugen TH, Hanley JM, Heath EC. 1981. Haptoglobin. A novel mode of biosynthesis of a liver secretory glycoprotein. J Biol Chem 256: 1055–1057.
    • (1981) J Biol Chem , vol.256 , pp. 1055-1057
    • Haugen, TH1    Hanley, JM2    Heath, EC3
  • 20
    • 14744284712 scopus 로고    scopus 로고
    • Multiple mechanisms of cytokine action in neurodegenerative and psychiatric states:neurochemical and molecular substrates
    • Hayley S, Anisman H. 2005. Multiple mechanisms of cytokine action in neurodegenerative and psychiatric states:neurochemical and molecular substrates. Curr Pharm Des 11: 947–962.
    • (2005) Curr Pharm Des , vol.11 , pp. 947-962
    • Hayley, S1    Anisman, H2
  • 21
    • 0036714747 scopus 로고    scopus 로고
    • A meta‐analysis of coffee drinking, cigarette smoking, and the risk of Parkinson's disease
    • Hernan MA, Takkouche B, Caamano‐Isorna F, Gestal‐Otero JJ. 2002. A meta‐analysis of coffee drinking, cigarette smoking, and the risk of Parkinson's disease. Ann Neurol 52: 276–284.
    • (2002) Ann Neurol , vol.52 , pp. 276-284
    • Hernan, MA1    Takkouche, B2    Caamano‐Isorna, F3    Gestal‐Otero, JJ4
  • 22
    • 0001699857 scopus 로고
    • The effect of haptoglobin‐polymer size on hemoglobin binding capacity
    • Javid J. 1965. The effect of haptoglobin‐polymer size on hemoglobin binding capacity. Vox Sang 10: 320–325.
    • (1965) Vox Sang , vol.10 , pp. 320-325
    • Javid, J1
  • 24
    • 0029084620 scopus 로고
    • Protein analysis of human maculae in relation to age‐related maculopathy
    • Kliffen M, de Jong PT, Luider TM. 1995. Protein analysis of human maculae in relation to age‐related maculopathy. Lab Invest 73: 267–272.
    • (1995) Lab Invest , vol.73 , pp. 267-272
    • Kliffen, M1    de Jong, PT2    Luider, TM3
  • 25
    • 0036720551 scopus 로고    scopus 로고
    • Genotyping of the common haptoglobin Hp 1/2 polymorphism based on PCR
    • Koch W, Latz W, Eichinger M, Roguin A, Levy AP, Schömig, Kastrati A. 2002. Genotyping of the common haptoglobin Hp 1/2 polymorphism based on PCR. Clin Chem 48: 1377–1382.
    • (2002) Clin Chem , vol.48 , pp. 1377-1382
    • Koch, W1    Latz, W2    Eichinger, M3    Roguin, A4    Levy, AP5    Schömig6    Kastrati, A7
  • 29
    • 0029854812 scopus 로고    scopus 로고
    • Biological and clinical significance of haptoglobin polymorphism in humans
    • Langlois MR, Delanghe JR. 1996. Biological and clinical significance of haptoglobin polymorphism in humans. Clin Chem 42: 1589–1600.
    • (1996) Clin Chem , vol.42 , pp. 1589-1600
    • Langlois, MR1    Delanghe, JR2
  • 31
    • 0021288584 scopus 로고
    • Duplication within the haptoglobin Hp2 gene
    • Maeda N, Yang F, Barnett DR, Bowman BH, Smithies O. 1984. Duplication within the haptoglobin Hp 2 gene. Nature 309: 131–135.
    • (1984) Nature , vol.309 , pp. 131-135
    • Maeda, N1    Yang, F2    Barnett, DR3    Bowman, BH4    Smithies, O5
  • 32
    • 29744442267 scopus 로고    scopus 로고
    • Gene expression profiling of sporadic Parkinson's disease substantia nigra pars compacta reveals impairment of ubiquitin‐proteasome subunits, SKP1A, aldehyde dehydrogenase, and chaperone HSC‐70
    • Mandel S, Grunblatt E, Riederer P, Amariglio N, Hirsch JJ, Rechavi G, Youdim MBH. 2005. Gene expression profiling of sporadic Parkinson's disease substantia nigra pars compacta reveals impairment of ubiquitin‐proteasome subunits, SKP1A, aldehyde dehydrogenase, and chaperone HSC‐70. Ann N Y Acad Sci 1053: 356–375.
    • (2005) Ann N Y Acad Sci , vol.1053 , pp. 356-375
    • Mandel, S1    Grunblatt, E2    Riederer, P3    Amariglio, N4    Hirsch, JJ5    Rechavi, G6    Youdim, MBH7
  • 34
    • 0025678674 scopus 로고
    • Hemoglobin binding with haptoglobin: Delineation of the haptoglobin binding site on the alpha‐chain of human hemoglobin
    • McCormick DJ, Atassi MZ. 1990. Hemoglobin binding with haptoglobin: Delineation of the haptoglobin binding site on the alpha‐chain of human hemoglobin. J Protein Chem 9: 735–742.
    • (1990) J Protein Chem , vol.9 , pp. 735-742
    • McCormick, DJ1    Atassi, MZ2
  • 35
    • 0021601416 scopus 로고
    • Localization of the haptoglobin alpha and beta genes (HPA and HPB) to human chromosome 16q22 by in situ hybridization
    • McGill JR, Yang F, Baldwin WD, Brune JL, Barnett DR, Bowman BH, Moore CM. 1984. Localization of the haptoglobin alpha and beta genes (HPA and HPB) to human chromosome 16q22 by in situ hybridization. Cytogenet Cell Genet 38: 155–157.
    • (1984) Cytogenet Cell Genet , vol.38 , pp. 155-157
    • McGill, JR1    Yang, F2    Baldwin, WD3    Brune, JL4    Barnett, DR5    Bowman, BH6    Moore, CM7
  • 36
  • 37
    • 33750330754 scopus 로고    scopus 로고
    • CYP450, genetics and Parkinson's disease: Gene × environment interactions hold the key
    • Mellick GD. 2006. CYP450, genetics and Parkinson's disease: Gene × environment interactions hold the key. J Neural Transm Suppl (70:) 159–165.
    • (2006) J Neural Transm Suppl , vol.70 , pp. 159-165
    • Mellick, GD1
  • 38
    • 0030582991 scopus 로고    scopus 로고
    • Interleukin (IL)‐1 beta, IL‐2, IL‐4, IL‐6 and transforming growth factor‐alpha levels are elevated in ventricular cerebrospinal fluid in juvenile parkinsonism and Parkinson's disease
    • Mogi M, Harada M, Narabayashi H, Inagaki H, Minami M, Nagatsu T. 1996. Interleukin (IL)‐1 beta, IL‐2, IL‐4, IL‐6 and transforming growth factor‐alpha levels are elevated in ventricular cerebrospinal fluid in juvenile parkinsonism and Parkinson's disease. Neurosci Lett 211: 13–16.
    • (1996) Neurosci Lett , vol.211 , pp. 13-16
    • Mogi, M1    Harada, M2    Narabayashi, H3    Inagaki, H4    Minami, M5    Nagatsu, T6
  • 39
    • 0014329393 scopus 로고
    • Association between response to typhoid vaccination and known genetic markers
    • Nevo S, Sutton H. 1979. Association between response to typhoid vaccination and known genetic markers. Am J Hum Genet 20: 461–469.
    • (1979) Am J Hum Genet , vol.20 , pp. 461-469
    • Nevo, S1    Sutton, H2
  • 40
    • 0034663039 scopus 로고    scopus 로고
    • The A53T α‐synuclein mutation increases iron‐dependent aggregation and toxicity
    • Ostrerova‐Golts N, Petrucelli L, Hardy J, Lee JM, Farer M, Wolozin B. 2000. The A53T α‐synuclein mutation increases iron‐dependent aggregation and toxicity. J Neurosci 20: 6048–6054.
    • (2000) J Neurosci , vol.20 , pp. 6048-6054
    • Ostrerova‐Golts, N1    Petrucelli, L2    Hardy, J3    Lee, JM4    Farer, M5    Wolozin, B6
  • 41
    • 3242710339 scopus 로고    scopus 로고
    • The influence of systemic inflammation on inflammation in the brain: Implications for chronic neurodegenerative disease
    • Perry VH. 2004. The influence of systemic inflammation on inflammation in the brain: Implications for chronic neurodegenerative disease. Brain Behav Immun 18: 407–413.
    • (2004) Brain Behav Immun , vol.18 , pp. 407-413
    • Perry, VH1
  • 42
    • 0347951196 scopus 로고    scopus 로고
    • Hemoglobin scavenger receptor CD163 mediates interleukin‐10 release and heme oxygenase‐1 synthesis: Antiinflammatory monocyte‐macrophage responses in vitro, in resolving skin blisters in vivo, and after cardiopulmonary bypass surgery
    • Philippidis P, Mason JC, Evans BJ, Nadra I, Taylor KM, Haskard DO, Landis RC. 2004. Hemoglobin scavenger receptor CD163 mediates interleukin‐10 release and heme oxygenase‐1 synthesis: Antiinflammatory monocyte‐macrophage responses in vitro, in resolving skin blisters in vivo, and after cardiopulmonary bypass surgery. Circ Res 94: 119–126.
    • (2004) Circ Res , vol.94 , pp. 119-126
    • Philippidis, P1    Mason, JC2    Evans, BJ3    Nadra, I4    Taylor, KM5    Haskard, DO6    Landis, RC7
  • 43
    • 4043177112 scopus 로고    scopus 로고
    • Haptoglobin phenotypes in health and disorders
    • Sadrzadeh SMH, Bozorgmehr J. 2004. Haptoglobin phenotypes in health and disorders. Am J Clin Pathol 121 (Suppl): S97–S104.
    • (2004) Am J Clin Pathol , vol.121 , Issue.Suppl , pp. S97-S104
    • Sadrzadeh, SMH1    Bozorgmehr, J2
  • 45
    • 0013137570 scopus 로고
    • Nature and metabolism of extracellular proteins, Vol 1, Molecular biology of human proteins
    • Schultze HE, Heremans JF. 1966. Nature and metabolism of extracellular proteins, Vol 1, Molecular biology of human proteins. Amsterdam: Elsevier. p 384–402.
    • (1966) , pp. 384-402
    • Schultze, HE1    Heremans, JF2
  • 46
    • 1642555537 scopus 로고    scopus 로고
    • Iron involvement in neural damage and microgliosis in models of neurodegenerative diseases
    • Shoham S, Youdim MBH. 2000. Iron involvement in neural damage and microgliosis in models of neurodegenerative diseases. Cell Mol Biol 46: 743–760.
    • (2000) Cell Mol Biol , vol.46 , pp. 743-760
    • Shoham, S1    Youdim, MBH2
  • 47
    • 0345582990 scopus 로고
    • Zone electrophoresis in starch gels: Group variations in the serum proteins of normal human adults
    • Smithies O. 1955. Zone electrophoresis in starch gels: Group variations in the serum proteins of normal human adults. Biochem J 61: 629–641.
    • (1955) Biochem J , vol.61 , pp. 629-641
    • Smithies, O1
  • 48
    • 4644234505 scopus 로고    scopus 로고
    • VEGF: Once regarded as a specific angiogenic factor, now implicated in neuroprotection
    • Storkebaum E, Lambrechts D, Carmeliet P. 2004. VEGF: Once regarded as a specific angiogenic factor, now implicated in neuroprotection. BioEssays 26: 943–954.
    • (2004) BioEssays , vol.26 , pp. 943-954
    • Storkebaum, E1    Lambrechts, D2    Carmeliet, P3
  • 50
    • 33645921304 scopus 로고    scopus 로고
    • Regulation of surface CD163 expression and cellular effects of receptor mediated hemoglobin–haptoglobin uptake on human monocytes and macrophages
    • Ugocsai P, Barlage S, Dada A, Schmitz G. 2006. Regulation of surface CD163 expression and cellular effects of receptor mediated hemoglobin–haptoglobin uptake on human monocytes and macrophages. Cytometry A 69: 203–205.
    • (2006) Cytometry A , vol.69 , pp. 203-205
    • Ugocsai, P1    Barlage, S2    Dada, A3    Schmitz, G4
  • 52
    • 0021760884 scopus 로고
    • Characterization of human haptoglobin cDNAs coding for alpha 2FS beta and alpha 1S beta variants
    • Van der Straten A, Herzog A, Cabezon T, Bollen A. 1984. Characterization of human haptoglobin cDNAs coding for alpha 2FS beta and alpha 1S beta variants. FEBS Lett 168: 103–107.
    • (1984) FEBS Lett , vol.168 , pp. 103-107
    • Van der Straten, A1    Herzog, A2    Cabezon, T3    Bollen, A4
  • 53
    • 2942542718 scopus 로고    scopus 로고
    • Haptoglobin polymorphisms and iron homeostasis in health and in disease
    • Van Vlierberghe H, Langlois M, Delanghe J. 2004. Haptoglobin polymorphisms and iron homeostasis in health and in disease. Clin Chim Acta 345: 35–42.
    • (2004) Clin Chim Acta , vol.345 , pp. 35-42
    • Van Vlierberghe, H1    Langlois, M2    Delanghe, J3
  • 55
    • 0025736680 scopus 로고
    • Iron in brain function and dysfunction with emphasis on Parkinson's disease
    • Youdim MB, Ben‐Shachar D, Riederer P. 1991. Iron in brain function and dysfunction with emphasis on Parkinson's disease. Eur Neurol 31 (Suppl 1): S34–S40.
    • (1991) Eur Neurol , vol.31 , Issue.Suppl 1 , pp. S34-S40
    • Youdim, MB1    Ben‐Shachar, D2    Riederer, P3
  • 56
    • 1842608744 scopus 로고    scopus 로고
    • Iron out iron in Parkinson's disease and other neurodegenerative diseases with iron chelators: A lesson from 6‐hydroxydopamine and iron chelators desferal and VK‐28
    • Youdim MB, Stephenson G, Ben Shachar D. 2004. Iron out iron in Parkinson's disease and other neurodegenerative diseases with iron chelators: A lesson from 6‐hydroxydopamine and iron chelators desferal and VK‐28. Ann NY Acad Sci 1012: 306–326.
    • (2004) Ann NY Acad Sci , vol.1012 , pp. 306-326
    • Youdim, MB1    Stephenson, G2    Ben Shachar, D3


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