메뉴 건너뛰기




Volumn 21, Issue 2, 2008, Pages 189-195

Neurophysiology and psychobiology of the placebo response

Author keywords

Brain imaging; Clinical trials; Depression; Neurophysiology; Pain; Placebo response

Indexed keywords

BRAIN RADIOGRAPHY; BRAIN SCINTISCANNING; CLINICAL STUDY; CONCEPTUAL FRAMEWORK; CONDITIONING; DEPRESSION; ETHICS; HUMAN; IMAGING; MEDICAL RESEARCH; NEUROPHYSIOLOGY; PAIN; PATIENT CARE; PLACEBO EFFECT; PSYCHOBIOLOGY; REVIEW; STATISTICAL ANALYSIS;

EID: 40349094461     PISSN: 09517367     EISSN: None     Source Type: Journal    
DOI: 10.1097/YCO.0b013e3282f50c36     Document Type: Review
Times cited : (28)

References (71)
  • 1
    • 20044378862 scopus 로고    scopus 로고
    • The placebo response in functional bowel disorders: Perspectives and putative mechanisms
    • Enck P, Klosterhalfen S. The placebo response in functional bowel disorders: perspectives and putative mechanisms. Neurogastroenterol Motil 2005; 17:325-331.
    • (2005) Neurogastroenterol Motil , vol.17 , pp. 325-331
    • Enck, P.1    Klosterhalfen, S.2
  • 2
    • 0037704429 scopus 로고    scopus 로고
    • Conscious expectation and unconscious conditioning in analgesic, motor, and hormonal placebo/nocebo responses
    • Benedetti F, Pollo A, Lopiano L, et al. Conscious expectation and unconscious conditioning in analgesic, motor, and hormonal placebo/nocebo responses. J Neurosci 2003; 23:4315-4323.
    • (2003) J Neurosci , vol.23 , pp. 4315-4323
    • Benedetti, F.1    Pollo, A.2    Lopiano, L.3
  • 3
    • 33846804457 scopus 로고    scopus 로고
    • Classical conditioning and expectancy in placebo hypoalgesia: A randomized controlled study in patients with atopic dermatitis and persons with healthy skin
    • Klinger R, Soost S, Flor H, Worm M. Classical conditioning and expectancy in placebo hypoalgesia: a randomized controlled study in patients with atopic dermatitis and persons with healthy skin. Pain 2007; 128:31-39.
    • (2007) Pain , vol.128 , pp. 31-39
    • Klinger, R.1    Soost, S.2    Flor, H.3    Worm, M.4
  • 4
    • 33746807812 scopus 로고    scopus 로고
    • How prior experience shapes placebo analgesia
    • Colloca L, Benedetti F. How prior experience shapes placebo analgesia. Pain 2006; 124:126-133.
    • (2006) Pain , vol.124 , pp. 126-133
    • Colloca, L.1    Benedetti, F.2
  • 5
    • 0036803108 scopus 로고    scopus 로고
    • A comparison of placebo effects in clinical analgesic trials versus studies of placebo analgesia
    • Vase L, Riley JL 3rd, Price DD. A comparison of placebo effects in clinical analgesic trials versus studies of placebo analgesia. Pain 2002; 99:443-452.
    • (2002) Pain , vol.99 , pp. 443-452
    • Vase, L.1    Riley 3rd, J.L.2    Price, D.D.3
  • 6
    • 8744229903 scopus 로고    scopus 로고
    • Long-term safety and efficacy of alosetron in women with severe diarrhea-predominant irritable bowel syndrome
    • Chey WD, Chey WY, Heath AT, et al. Long-term safety and efficacy of alosetron in women with severe diarrhea-predominant irritable bowel syndrome. Am J Gastroenterol 2004; 99:2185-2203.
    • (2004) Am J Gastroenterol , vol.99 , pp. 2185-2203
    • Chey, W.D.1    Chey, W.Y.2    Heath, A.T.3
  • 7
    • 0036500024 scopus 로고    scopus 로고
    • Placebo and opioid analgesia: Imaging a shared neuronal network
    • Petrovic P, Kalso E, Petersson KM, Ingvar M. Placebo and opioid analgesia: imaging a shared neuronal network. Science 2002; 295:1737-1740.
    • (2002) Science , vol.295 , pp. 1737-1740
    • Petrovic, P.1    Kalso, E.2    Petersson, K.M.3    Ingvar, M.4
  • 8
    • 1242352025 scopus 로고    scopus 로고
    • Placebo-induced changes in fMRI in the anticipation and experience of pain
    • Wager TD, Rittling JK, Smith EE, et al. Placebo-induced changes in fMRI in the anticipation and experience of pain. Science 2004; 303:1162-1167.
    • (2004) Science , vol.303 , pp. 1162-1167
    • Wager, T.D.1    Rittling, J.K.2    Smith, E.E.3
  • 9
    • 17844410396 scopus 로고    scopus 로고
    • Expectancy and belief modulate the neuronal substrates of pain treated by acupuncture
    • Pariente J, White P, Frackowiak RS, Lewith G. Expectancy and belief modulate the neuronal substrates of pain treated by acupuncture. Neuroimage 2005; 25:1161-1167.
    • (2005) Neuroimage , vol.25 , pp. 1161-1167
    • Pariente, J.1    White, P.2    Frackowiak, R.S.3    Lewith, G.4
  • 10
    • 23944464949 scopus 로고    scopus 로고
    • Placebo effects mediated by endogenous opioid activity on mu-opioid receptors
    • Zubieta JK, Bueller JA, Jackson LR, et al. Placebo effects mediated by endogenous opioid activity on mu-opioid receptors. J Neurosci 2005; 25:7754-7762.
    • (2005) J Neurosci , vol.25 , pp. 7754-7762
    • Zubieta, J.K.1    Bueller, J.A.2    Jackson, L.R.3
  • 11
    • 30544433435 scopus 로고    scopus 로고
    • Mechanisms of placebo analgesia: RACC recruitment of a subcortical antinociceptive network
    • Bingel U, Lorenz J, Schoell E, et al. Mechanisms of placebo analgesia: rACC recruitment of a subcortical antinociceptive network. Pain 2006; 120:8-15.
    • (2006) Pain , vol.120 , pp. 8-15
    • Bingel, U.1    Lorenz, J.2    Schoell, E.3
  • 12
    • 32544444712 scopus 로고    scopus 로고
    • Brain activity associated with expectancy-enhanced placebo analgesia as measured by functional magnetic resonance imaging
    • Kong J, Gollub RL, Rosman IS, et al. Brain activity associated with expectancy-enhanced placebo analgesia as measured by functional magnetic resonance imaging. J Neurosci 2006; 26:381-388.
    • (2006) J Neurosci , vol.26 , pp. 381-388
    • Kong, J.1    Gollub, R.L.2    Rosman, I.S.3
  • 13
    • 34547442316 scopus 로고    scopus 로고
    • Placebo effects on human μ-opioid activity during pain
    • This important paper identifies, by connectivity analysis of fMRI data, two major cortical networks that contribute to the placebo response in experimental pain: one that processes the noxious stimulus and one that is activated in anticipation of pain; both are based on m-opioid activity, but show individual variation
    • Wager TD, Scott DJ, Zubieta JK. Placebo effects on human μ-opioid activity during pain. Proc Natl Acad Sci U S A 2007; 104:11056-11061. This important paper identifies - by connectivity analysis of fMRI data - two major cortical networks that contribute to the placebo response in experimental pain: one that processes the noxious stimulus and one that is activated in anticipation of pain; both are based on m-opioid activity, but show individual variation.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 11056-11061
    • Wager, T.D.1    Scott, D.J.2    Zubieta, J.K.3
  • 14
    • 34249019013 scopus 로고    scopus 로고
    • Placebo analgesia: A PET study
    • Nemoto H, Nemoto Y, Toda H, et al. Placebo analgesia: a PET study. Exp Brain Res 2007; 179:655-664.
    • (2007) Exp Brain Res , vol.179 , pp. 655-664
    • Nemoto, H.1    Nemoto, Y.2    Toda, H.3
  • 15
    • 0035838997 scopus 로고    scopus 로고
    • Expectation and dopamine release: Mechanism of the placebo effect in Parkinson's disease
    • de la Fuente-Fernandez R, Ruth TJ, Sossi V, et al. Expectation and dopamine release: mechanism of the placebo effect in Parkinson's disease. Science 2001; 293:1164-1166.
    • (2001) Science , vol.293 , pp. 1164-1166
    • de la Fuente-Fernandez, R.1    Ruth, T.J.2    Sossi, V.3
  • 16
    • 0036356299 scopus 로고    scopus 로고
    • Changes in brain function of depressed subjects during treatment with placebo
    • Leuchter AF, Cook IA, Witte EA, et al. Changes in brain function of depressed subjects during treatment with placebo. Am J Psychiatry 2002; 159:122-129.
    • (2002) Am J Psychiatry , vol.159 , pp. 122-129
    • Leuchter, A.F.1    Cook, I.A.2    Witte, E.A.3
  • 17
    • 0036237860 scopus 로고    scopus 로고
    • The functional neuroanatomy of the placebo effect
    • Mayberg HS, Silva JA, Brannan SK, et al. The functional neuroanatomy of the placebo effect. Am J Psychiatry 2002; 159:728-737.
    • (2002) Am J Psychiatry , vol.159 , pp. 728-737
    • Mayberg, H.S.1    Silva, J.A.2    Brannan, S.K.3
  • 18
    • 15444378006 scopus 로고    scopus 로고
    • Neurophysiologic correlates of side effects in normal subjects randomized to venlafaxine or placebo
    • Hunter AM, Leuchter AF, Morgan ML, et al. Neurophysiologic correlates of side effects in normal subjects randomized to venlafaxine or placebo. Neuropsychopharmacology 2005; 30:792-799.
    • (2005) Neuropsychopharmacology , vol.30 , pp. 792-799
    • Hunter, A.M.1    Leuchter, A.F.2    Morgan, M.L.3
  • 19
    • 85047700106 scopus 로고    scopus 로고
    • Changes in brain function (quantitative EEG cordance) during placebo lead-in and treatment outcomes in clinical trials for major depression
    • Hunter AM, Leuchter AF, Morgan ML, Cook IA. Changes in brain function (quantitative EEG cordance) during placebo lead-in and treatment outcomes in clinical trials for major depression. Am J Psychiatry 2006; 163:1426-1432.
    • (2006) Am J Psychiatry , vol.163 , pp. 1426-1432
    • Hunter, A.M.1    Leuchter, A.F.2    Morgan, M.L.3    Cook, I.A.4
  • 20
    • 1942446313 scopus 로고    scopus 로고
    • The neural correlates of placebo effects: A disruption account
    • Lieberman MD, Jarcho JM, Berman S, et al. The neural correlates of placebo effects: a disruption account. Neuroimage 2004; 22:447-455.
    • (2004) Neuroimage , vol.22 , pp. 447-455
    • Lieberman, M.D.1    Jarcho, J.M.2    Berman, S.3
  • 21
    • 35448957971 scopus 로고    scopus 로고
    • Functional brain interactions that serve cognitive-affective processing during pain and placebo analgesia
    • This important paper investigated the brain processes of visceral nociceptive stimuli in female patients with IBS and shows that two placebo analgesia networks (one for nociceptive processing and one for affective processing) operate in a self-reinforcing feedback loop to maintain placebo analgesia
    • Craggs JG, Price DD, Verne GN, et al. Functional brain interactions that serve cognitive-affective processing during pain and placebo analgesia. Neuroimage 2007; 38:720-729. This important paper investigated the brain processes of visceral nociceptive stimuli in female patients with IBS and shows that two placebo analgesia networks (one for nociceptive processing and one for affective processing) operate in a self-reinforcing feedback loop to maintain placebo analgesia.
    • (2007) Neuroimage , vol.38 , pp. 720-729
    • Craggs, J.G.1    Price, D.D.2    Verne, G.N.3
  • 22
    • 20344407823 scopus 로고    scopus 로고
    • Placebo neural systems: Nitric oxide, morphine and the dopamine brain reward and motivation circuitries
    • Fricchione G, Stefano GB. Placebo neural systems: nitric oxide, morphine and the dopamine brain reward and motivation circuitries. Med Sci Monit 2005; 11:54-65.
    • (2005) Med Sci Monit , vol.11 , pp. 54-65
    • Fricchione, G.1    Stefano, G.B.2
  • 23
    • 21744454896 scopus 로고    scopus 로고
    • Placebos and painkillers: Is mind as real as matter?
    • Colloca L, Benedetti F. Placebos and painkillers: is mind as real as matter? Nat Rev Neurosci 2005; 6:545-552.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 545-552
    • Colloca, L.1    Benedetti, F.2
  • 24
    • 33947634053 scopus 로고    scopus 로고
    • Mind does really matter: Evidence from neuroimaging studies of emotional self-regulation, psychotherapy, and placebo effect
    • This review paper summarizes and links neuroimaging studies in the field of psychophysiology emotion, psychotherapy, and the placebo effect and proposes a translational concept of psycho-neural understanding
    • Beauregard M. Mind does really matter: evidence from neuroimaging studies of emotional self-regulation, psychotherapy, and placebo effect. Prog Neurobiol 2007; 81:218-236. This review paper summarizes and links neuroimaging studies in the field of psychophysiology (emotion), psychotherapy, and the placebo effect and proposes a translational concept of psycho-neural understanding
    • (2007) Prog Neurobiol , vol.81 , pp. 218-236
    • Beauregard, M.1
  • 25
    • 35348876625 scopus 로고    scopus 로고
    • Understanding the placebo effect: Contributions from neuroimaging
    • This review paper summarizes the current imaging literature of the placebo response specifically in Parkinson's disease and proposed the relevance of an endogenous striatum dopaminergic reward system
    • Lidstone SC, Stoessl AJ. Understanding the placebo effect: contributions from neuroimaging. Mol Imaging Biol 2007; 9:176-185. This review paper summarizes the current imaging literature of the placebo response specifically in Parkinson's disease and proposed the relevance of an endogenous striatum dopaminergic reward system.
    • (2007) Mol Imaging Biol , vol.9 , pp. 176-185
    • Lidstone, S.C.1    Stoessl, A.J.2
  • 26
    • 34547883489 scopus 로고    scopus 로고
    • Brain mechanisms underlying the placebo effect in neurological disorders
    • Cavanna AE, Strigaro G, Monaco F. Brain mechanisms underlying the placebo effect in neurological disorders. Funct Neurol 2007; 22:89-94.
    • (2007) Funct Neurol , vol.22 , pp. 89-94
    • Cavanna, A.E.1    Strigaro, G.2    Monaco, F.3
  • 27
    • 13844253844 scopus 로고    scopus 로고
    • Association of striatal dopamine D2/D3 receptor binding potential with pain but not tactile sensitivity or placebo analgesia
    • Martikainen IK, Hagelberg N, Mansikka H, et al. Association of striatal dopamine D2/D3 receptor binding potential with pain but not tactile sensitivity or placebo analgesia. Neurosci Lett 2005; 376:149-153.
    • (2005) Neurosci Lett , vol.376 , pp. 149-153
    • Martikainen, I.K.1    Hagelberg, N.2    Mansikka, H.3
  • 28
    • 35748956751 scopus 로고    scopus 로고
    • Revelation of a personal placebo response: Its effects on mood, attitudes and future placebo responding
    • Chung SK, Price DD, Verne GN, Robinson ME. Revelation of a personal placebo response: its effects on mood, attitudes and future placebo responding. Pain 2007; 132:281-288.
    • (2007) Pain , vol.132 , pp. 281-288
    • Chung, S.K.1    Price, D.D.2    Verne, G.N.3    Robinson, M.E.4
  • 29
    • 34447255415 scopus 로고    scopus 로고
    • Scott DJ, Stohler CS, Egnatuk CM, et al. Individual differences in reward responding explain placebo-induced expectations and effects. Neuron 2007; 55:325-336. This important paper associates placebo analgesia as measured by PET dopamine binding with individual responsiveness to a monetary reward game (in an fMRI paradigm) to allow assessment of individual variation in placebo analgesia formation.
    • Scott DJ, Stohler CS, Egnatuk CM, et al. Individual differences in reward responding explain placebo-induced expectations and effects. Neuron 2007; 55:325-336. This important paper associates placebo analgesia as measured by PET dopamine binding with individual responsiveness to a monetary reward game (in an fMRI paradigm) to allow assessment of individual variation in placebo analgesia formation.
  • 30
    • 29144516421 scopus 로고    scopus 로고
    • Belief or need? Accounting for individual variations in the neurochemistry of the placebo effect
    • Zubieta JK, Yau WY, Scott DJ, Stohler CS. Belief or need? Accounting for individual variations in the neurochemistry of the placebo effect. Brain Behav Immun 2006; 20:15-26.
    • (2006) Brain Behav Immun , vol.20 , pp. 15-26
    • Zubieta, J.K.1    Yau, W.Y.2    Scott, D.J.3    Stohler, C.S.4
  • 31
    • 32544436540 scopus 로고    scopus 로고
    • Placebo-induced changes in spinal cord pain processing
    • Matre D, Casey KL, Knardahl S. Placebo-induced changes in spinal cord pain processing. J Neurosci 2006; 26:559-563.
    • (2006) J Neurosci , vol.26 , pp. 559-563
    • Matre, D.1    Casey, K.L.2    Knardahl, S.3
  • 32
    • 34247610442 scopus 로고    scopus 로고
    • Placebo analgesia is not due to compliance or habituation: EEG and behavioural evidence
    • Watson A, El-Deredy W, Vogt BA, Jones AK. Placebo analgesia is not due to compliance or habituation: EEG and behavioural evidence. Neuroreport 2007; 18:771-775.
    • (2007) Neuroreport , vol.18 , pp. 771-775
    • Watson, A.1    El-Deredy, W.2    Vogt, B.A.3    Jones, A.K.4
  • 33
    • 0031775604 scopus 로고    scopus 로고
    • Gender differences in pain perception and patterns of cerebral activation during noxious heat stimulation in humans
    • Paulson PE, Minoshima S, Morrow TJ, Casey KL. Gender differences in pain perception and patterns of cerebral activation during noxious heat stimulation in humans. Pain 1998; 76:223-229.
    • (1998) Pain , vol.76 , pp. 223-229
    • Paulson, P.E.1    Minoshima, S.2    Morrow, T.J.3    Casey, K.L.4
  • 34
    • 0034210451 scopus 로고    scopus 로고
    • Gender differences in regional brain response to visceral pressure in IBS patients
    • Berman S, Munakata J, Naliboff BD, et al. Gender differences in regional brain response to visceral pressure in IBS patients. Eur J Pain 2000; 4:157-172.
    • (2000) Eur J Pain , vol.4 , pp. 157-172
    • Berman, S.1    Munakata, J.2    Naliboff, B.D.3
  • 35
    • 2442665089 scopus 로고    scopus 로고
    • Affective picture perception: Gender differences in visual cortex?
    • Sabatinelli D, Flaisch T, Bradley MM, et al. Affective picture perception: gender differences in visual cortex? Neuroreport 2004; 15:1109-1112.
    • (2004) Neuroreport , vol.15 , pp. 1109-1112
    • Sabatinelli, D.1    Flaisch, T.2    Bradley, M.M.3
  • 36
    • 33748374244 scopus 로고    scopus 로고
    • There are differences in cerebral activation between females in distinct menstrual phases during viewing of erotic stimuli: A fMRI study
    • Gizewski ER, Krause E, Karama S, et al. There are differences in cerebral activation between females in distinct menstrual phases during viewing of erotic stimuli: a fMRI study. Exp Brain Res 2006; 174:101-108.
    • (2006) Exp Brain Res , vol.174 , pp. 101-108
    • Gizewski, E.R.1    Krause, E.2    Karama, S.3
  • 37
    • 33745283389 scopus 로고    scopus 로고
    • Cognitive and emotional factors in placebo analgesia
    • Flaten MA, Aslaksen PM, Finset A, et al. Cognitive and emotional factors in placebo analgesia. J Psychosom Res 2006; 61:81-89.
    • (2006) J Psychosom Res , vol.61 , pp. 81-89
    • Flaten, M.A.1    Aslaksen, P.M.2    Finset, A.3
  • 38
    • 5644220631 scopus 로고    scopus 로고
    • The effects of experimenter characteristics on pain reports in women and men
    • Kallai I, Barke A, Voss U. The effects of experimenter characteristics on pain reports in women and men. Pain 2004; 112:142-147.
    • (2004) Pain , vol.112 , pp. 142-147
    • Kallai, I.1    Barke, A.2    Voss, U.3
  • 39
    • 0345167992 scopus 로고    scopus 로고
    • The placebo needle, is it a valid and convincing placebo for use in acupuncture trials? A randomised, single-blind, cross-over pilot trial
    • White P, Lewith G, Hopwood V, Prescott P. The placebo needle, is it a valid and convincing placebo for use in acupuncture trials? A randomised, single-blind, cross-over pilot trial. Pain 2003; 106:401-409.
    • (2003) Pain , vol.106 , pp. 401-409
    • White, P.1    Lewith, G.2    Hopwood, V.3    Prescott, P.4
  • 40
    • 27744489898 scopus 로고    scopus 로고
    • The effects of ethnicity and gender on motion sickness susceptibility
    • Klosterhalfen S, Kellermann S, Pan F, et al. The effects of ethnicity and gender on motion sickness susceptibility. Aviat Space Environ Med 2005; 76:1051-1057.
    • (2005) Aviat Space Environ Med , vol.76 , pp. 1051-1057
    • Klosterhalfen, S.1    Kellermann, S.2    Pan, F.3
  • 41
    • 40349095396 scopus 로고    scopus 로고
    • Women respond to conditioning, and men to suggestion of nausea
    • Klosterhalfen S, Kellermann S, Braun S, et al. Women respond to conditioning, and men to suggestion of nausea. Gastroeenterology 2007; 132:A133f.
    • (2007) Gastroeenterology , vol.132
    • Klosterhalfen, S.1    Kellermann, S.2    Braun, S.3
  • 42
    • 33750319479 scopus 로고    scopus 로고
    • Gender and race as determinants of nausea induced by circular vection
    • Klosterhalfen S, Pan F, Kellermann S, Enck P. Gender and race as determinants of nausea induced by circular vection. Gender Med 2006; 3:236-242.
    • (2006) Gender Med , vol.3 , pp. 236-242
    • Klosterhalfen, S.1    Pan, F.2    Kellermann, S.3    Enck, P.4
  • 43
    • 34848851621 scopus 로고    scopus 로고
    • Effects of instructions on responses to the nicotine patch: A laboratory study
    • Fucito LM, Juliano LM. Effects of instructions on responses to the nicotine patch: a laboratory study. Psychopharmacology (Berl) 2007; 194:475-483.
    • (2007) Psychopharmacology (Berl) , vol.194 , pp. 475-483
    • Fucito, L.M.1    Juliano, L.M.2
  • 44
    • 33746097841 scopus 로고    scopus 로고
    • The effects of manipulating expectations through placebo and nocebo administration on gastric tachyarrhythmia and motion-induced nausea
    • Levine ME, Stern RM, Koch KL. The effects of manipulating expectations through placebo and nocebo administration on gastric tachyarrhythmia and motion-induced nausea. Psychosom Med 2006; 68:478-486.
    • (2006) Psychosom Med , vol.68 , pp. 478-486
    • Levine, M.E.1    Stern, R.M.2    Koch, K.L.3
  • 46
    • 1242284494 scopus 로고    scopus 로고
    • Placebo treatment is effective differently in different diseases - but is it also harmless? A brief synopsis
    • Weihrauch TR. Placebo treatment is effective differently in different diseases - but is it also harmless? A brief synopsis. Sci Eng Ethics 2004; 10:151-155.
    • (2004) Sci Eng Ethics , vol.10 , pp. 151-155
    • Weihrauch, T.R.1
  • 47
    • 31344471005 scopus 로고    scopus 로고
    • Medication-attributed adverse effects in placebo groups: Implications for assessment of adverse effects
    • Rief W, Avorn J, Barsky AJ. Medication-attributed adverse effects in placebo groups: implications for assessment of adverse effects. Arch Intern Med 2006; 166:155-160.
    • (2006) Arch Intern Med , vol.166 , pp. 155-160
    • Rief, W.1    Avorn, J.2    Barsky, A.J.3
  • 48
    • 34250204872 scopus 로고    scopus 로고
    • When words are painful: Unraveling the mechanisms of the nocebo effect
    • This important paper is the first comprehensive review on the nocebo phenomenon and postulates similar mechanisms (expectations, conditioning) for both
    • Benedetti F, Lanotte M, Lopiano L, Colloca L. When words are painful: unraveling the mechanisms of the nocebo effect. Neuroscience 2007; 147:260-271. This important paper is the first comprehensive review on the nocebo phenomenon and postulates similar mechanisms (expectations, conditioning) for both.
    • (2007) Neuroscience , vol.147 , pp. 260-271
    • Benedetti, F.1    Lanotte, M.2    Lopiano, L.3    Colloca, L.4
  • 49
    • 32944461856 scopus 로고    scopus 로고
    • Loss of expectation-related mechanisms in Alzheimer's disease makes analgesic therapies less effective
    • Benedetti F, Arduino C, Costa S, et al. Loss of expectation-related mechanisms in Alzheimer's disease makes analgesic therapies less effective. Pain 2006; 121:133-144.
    • (2006) Pain , vol.121 , pp. 133-144
    • Benedetti, F.1    Arduino, C.2    Costa, S.3
  • 50
    • 33751085385 scopus 로고    scopus 로고
    • The biochemical and neuroendocrine bases of the hyperalgesic nocebo effect
    • Benedetti F, Amanzio M, Vighetti S, Asteggiano G. The biochemical and neuroendocrine bases of the hyperalgesic nocebo effect. J Neurosci 2006; 26:12014-12022.
    • (2006) J Neurosci , vol.26 , pp. 12014-12022
    • Benedetti, F.1    Amanzio, M.2    Vighetti, S.3    Asteggiano, G.4
  • 51
    • 20044379425 scopus 로고    scopus 로고
    • The placebo effect in irritable bowel syndrometrials: A meta-analysis
    • Patel SM, Stason WB, Legedza A, et al. The placebo effect in irritable bowel syndrometrials: a meta-analysis. Neurogastroenterol Motil 2005; 17:332-340.
    • (2005) Neurogastroenterol Motil , vol.17 , pp. 332-340
    • Patel, S.M.1    Stason, W.B.2    Legedza, A.3
  • 52
    • 17644374537 scopus 로고    scopus 로고
    • Defining the predictors of the placebo response in irritable bowel syndrome
    • Pitz M, Cheang M, Bernstein CN. Defining the predictors of the placebo response in irritable bowel syndrome. Clin Gastroenterol Hepatol 2005; 3:237-247.
    • (2005) Clin Gastroenterol Hepatol , vol.3 , pp. 237-247
    • Pitz, M.1    Cheang, M.2    Bernstein, C.N.3
  • 53
    • 34447517730 scopus 로고    scopus 로고
    • Dorn SD, Kaptchuk TJ, Park JB, et al. A meta-analysis of the placebo response in complementary and alternative medicine trials of irritable bowel syndrome. Neurogastroenterol Motil 2007; 19:630-637. This metaanalysis reports that complementary and alternative medicine studies in IBS report a placebo response of similar size (40%) to conventional drug studies.
    • Dorn SD, Kaptchuk TJ, Park JB, et al. A meta-analysis of the placebo response in complementary and alternative medicine trials of irritable bowel syndrome. Neurogastroenterol Motil 2007; 19:630-637. This metaanalysis reports that complementary and alternative medicine studies in IBS report a placebo response of similar size (40%) to conventional drug studies.
  • 54
    • 40349090415 scopus 로고    scopus 로고
    • Fulda S, Wetter TC. Where dopamine meets opioids: a meta-analysis of the placebo effect in RLS treatment studies. Brain 2007; 11 October [Epub ahead of print]. This metaanalysis reports that the magnitude of the placebo response in restless-leg syndrome across 24 randomized controlled trials is 40%, but varies with outcomes chosen.
    • Fulda S, Wetter TC. Where dopamine meets opioids: a meta-analysis of the placebo effect in RLS treatment studies. Brain 2007; 11 October [Epub ahead of print]. This metaanalysis reports that the magnitude of the placebo response in restless-leg syndrome across 24 randomized controlled trials is 40%, but varies with outcomes chosen.
  • 55
    • 34548584073 scopus 로고    scopus 로고
    • Sysko R, Walsh BT. A systematic review of placebo response in studies of bipolar mania. J Clin Psychiatry 2007; 68:1213-1217. This systematic review reports the placebo response rates in bipolar mania and depression to be around 30% across 21 placebo-controlled studies.
    • Sysko R, Walsh BT. A systematic review of placebo response in studies of bipolar mania. J Clin Psychiatry 2007; 68:1213-1217. This systematic review reports the placebo response rates in bipolar mania and depression to be around 30% across 21 placebo-controlled studies.
  • 56
    • 35748971487 scopus 로고    scopus 로고
    • Placebo response in the prophylaxis of migraine: A meta-analysis
    • Macedo A, Banos JE, Farre M. Placebo response in the prophylaxis of migraine: a meta-analysis. Eur J Pain 2008; 12:68-75.
    • (2008) Eur J Pain , vol.12 , pp. 68-75
    • Macedo, A.1    Banos, J.E.2    Farre, M.3
  • 57
    • 0037051872 scopus 로고    scopus 로고
    • Placebo response in studies of major depression: Variable, substantial, and growing
    • Walsh BT, Seidman SN, Sysko R, Gould M. Placebo response in studies of major depression: variable, substantial, and growing. JAMA 2002; 287:1840-1847.
    • (2002) JAMA , vol.287 , pp. 1840-1847
    • Walsh, B.T.1    Seidman, S.N.2    Sysko, R.3    Gould, M.4
  • 58
    • 33644818564 scopus 로고    scopus 로고
    • A meta-analysis of the placebo response in acute migraine and how this response may be influenced by some of the characteristics of clinical trials
    • Macedo A, Farré M, Baños JE. A meta-analysis of the placebo response in acute migraine and how this response may be influenced by some of the characteristics of clinical trials. Eur J Clin Pharmacol 2006; 62:161-172.
    • (2006) Eur J Clin Pharmacol , vol.62 , pp. 161-172
    • Macedo, A.1    Farré, M.2    Baños, J.E.3
  • 59
    • 33846245890 scopus 로고    scopus 로고
    • Why do clinical trials fail? The problem of measurement error in clinical trials: Time to test new paradigms?
    • Kobak KA, Kane JM, Thase ME, Nierenberg AA. Why do clinical trials fail? The problem of measurement error in clinical trials: time to test new paradigms? J Clin Psychopharmacol 2007; 27:1-5.
    • (2007) J Clin Psychopharmacol , vol.27 , pp. 1-5
    • Kobak, K.A.1    Kane, J.M.2    Thase, M.E.3    Nierenberg, A.A.4
  • 60
    • 34547202143 scopus 로고    scopus 로고
    • Gøtzsche PC, Hróbjartsson A, Maric K, Tendal B. Data extraction errors in meta-analyses that use standardized mean differences. JAMA 2007; 298:430-437. This important meta-metaanalysis reports data extraction errors in the range of up to 70% (in seven of 10 metaanalyses included).
    • Gøtzsche PC, Hróbjartsson A, Maric K, Tendal B. Data extraction errors in meta-analyses that use standardized mean differences. JAMA 2007; 298:430-437. This important meta-metaanalysis reports data extraction errors in the range of up to 70% (in seven of 10 metaanalyses included).
  • 61
    • 0342902205 scopus 로고    scopus 로고
    • Is the placebo powerless? An analysis of clinical trials comparing placebo with no treatment
    • Hró bjartsson A, Gøtzsche PC. Is the placebo powerless? An analysis of clinical trials comparing placebo with no treatment. N Engl J Med 2001; 344:1594-1602.
    • (2001) N Engl J Med , vol.344 , pp. 1594-1602
    • Hró bjartsson, A.1    Gøtzsche, P.C.2
  • 62
    • 3242887419 scopus 로고    scopus 로고
    • Is the placebo powerless? Update of a systematic review with 52 new randomized trials comparing placebo with no treatment
    • Hróbjartsson A, Gøtzsche PC. Is the placebo powerless? Update of a systematic review with 52 new randomized trials comparing placebo with no treatment. J Intern Med 2004; 256:91-100.
    • (2004) J Intern Med , vol.256 , pp. 91-100
    • Hróbjartsson, A.1    Gøtzsche, P.C.2
  • 63
    • 40349100969 scopus 로고    scopus 로고
    • Meissner KI, Distel H, Mitzdorf U. Evidence for placebo effects on physical but not on biochemical outcome parameters: a review of clinical trials. BMC Med (in press).
    • Meissner KI, Distel H, Mitzdorf U. Evidence for placebo effects on physical but not on biochemical outcome parameters: a review of clinical trials. BMC Med (in press).
  • 64
    • 33847667607 scopus 로고    scopus 로고
    • The impact of patient expectations on outcomes in four randomized controlled trials of acupuncture in patients with chronic pain
    • Linde K, Witt CM, Streng A, et al. The impact of patient expectations on outcomes in four randomized controlled trials of acupuncture in patients with chronic pain. Pain 2007; 128:264-271.
    • (2007) Pain , vol.128 , pp. 264-271
    • Linde, K.1    Witt, C.M.2    Streng, A.3
  • 65
    • 32944461856 scopus 로고    scopus 로고
    • Loss of expectation-related mechanisms in Alzheimer's disease makes analgesic therapies less effective
    • Benedetti F, Arduino C, Costa S, et al. Loss of expectation-related mechanisms in Alzheimer's disease makes analgesic therapies less effective. Pain 2006; 121:133-144.
    • (2006) Pain , vol.121 , pp. 133-144
    • Benedetti, F.1    Arduino, C.2    Costa, S.3
  • 66
    • 34848893958 scopus 로고    scopus 로고
    • Placebo response in Parkinson trials using patient diaries: Sites do matter
    • Ondo WG. Placebo response in Parkinson trials using patient diaries: sites do matter. Clin Neuropharmacol 2007; 30:301-304.
    • (2007) Clin Neuropharmacol , vol.30 , pp. 301-304
    • Ondo, W.G.1
  • 67
    • 33645084271 scopus 로고    scopus 로고
    • Predictors of the placebo response in functional dyspepsia
    • Talley NJ, Locke GR, Lahr BD, et al. Predictors of the placebo response in functional dyspepsia. Aliment Pharmacol Ther 2006; 23:923-936.
    • (2006) Aliment Pharmacol Ther , vol.23 , pp. 923-936
    • Talley, N.J.1    Locke, G.R.2    Lahr, B.D.3
  • 68
    • 40349084697 scopus 로고    scopus 로고
    • Placebo response in a functional dyspepsia drug trial: Reanalysed
    • Enck P, Vinson B, Malfertheiner P, Klosterhalfen S. Placebo response in a functional dyspepsia drug trial: reanalysed. Gut 2007; 56 (Suppl. III):A8.
    • (2007) Gut , vol.56 , Issue.SUPPL. III
    • Enck, P.1    Vinson, B.2    Malfertheiner, P.3    Klosterhalfen, S.4
  • 69
    • 2942530936 scopus 로고    scopus 로고
    • Worsening of depressive symptoms prior to randomization in clinical trials: A possible screen for placebo responders?
    • Evans KR, Sills T, Wunderlich GR, McDonald HP. Worsening of depressive symptoms prior to randomization in clinical trials: a possible screen for placebo responders? J Psychiatr Res 2004; 38:437-444.
    • (2004) J Psychiatr Res , vol.38 , pp. 437-444
    • Evans, K.R.1    Sills, T.2    Wunderlich, G.R.3    McDonald, H.P.4
  • 70
    • 33845619513 scopus 로고    scopus 로고
    • Which factors predict placebo response in anxiety disorders and major depression? An analysis of placebo-controlled studies of escitalopram
    • Stein DJ, Baldwin DS, Dolberg OT, et al. Which factors predict placebo response in anxiety disorders and major depression? An analysis of placebo-controlled studies of escitalopram. J Clin Psychiatry 2006; 67:1741-1746.
    • (2006) J Clin Psychiatry , vol.67 , pp. 1741-1746
    • Stein, D.J.1    Baldwin, D.S.2    Dolberg, O.T.3
  • 71
    • 33645759446 scopus 로고    scopus 로고
    • Identifying baseline characteristics of placebo responders versus nonresponders in randomized double-blind trials of refractory partial-onset seizures
    • Niklson I, Edrich P, Verdru P. Identifying baseline characteristics of placebo responders versus nonresponders in randomized double-blind trials of refractory partial-onset seizures. Epileptic Disord 2006; 8:37-44.
    • (2006) Epileptic Disord , vol.8 , pp. 37-44
    • Niklson, I.1    Edrich, P.2    Verdru, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.