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Volumn 246, Issue 1, 2008, Pages 63-72

Dietary clofibrate stimulates the formation and size of estradiol-induced breast tumors in female August-Copenhagen Irish (ACI) rats

Author keywords

Breast cancer; Clofibrate (2 (4 chlorophenoxy) 2 methyl propanoic acid; Estradiol; ethyl ester)

Indexed keywords

CLOFIBRATE; ESTRADIOL; FATTY ACID; GLUCURONOSYLTRANSFERASE; LIVER ENZYME;

EID: 40249116627     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2007.12.025     Document Type: Article
Times cited : (5)

References (38)
  • 1
    • 0036309549 scopus 로고    scopus 로고
    • Catechol ortho-quinones: the electrophilic compounds that form depurinating DNA adducts and could initiate cancer and other diseases
    • Cavalieri E.L., Li K., Balu N., Saeed M., Devanesan P., Higginbotham S., Zhao J., Gross L.M., and Rogan E.G. Catechol ortho-quinones: the electrophilic compounds that form depurinating DNA adducts and could initiate cancer and other diseases. Carcinogenesis 23 (2002) 1071-1077
    • (2002) Carcinogenesis , vol.23 , pp. 1071-1077
    • Cavalieri, E.L.1    Li, K.2    Balu, N.3    Saeed, M.4    Devanesan, P.5    Higginbotham, S.6    Zhao, J.7    Gross, L.M.8    Rogan, E.G.9
  • 3
    • 33645993864 scopus 로고    scopus 로고
    • Quinone reductase induction as a biomarker for cancer chemoprotection
    • Cuendet M., Oteham C.P., Moon R.C., and Pezzuto J.M. Quinone reductase induction as a biomarker for cancer chemoprotection. J. Nat. Prod. 69 (2006) 460-463
    • (2006) J. Nat. Prod. , vol.69 , pp. 460-463
    • Cuendet, M.1    Oteham, C.P.2    Moon, R.C.3    Pezzuto, J.M.4
  • 6
    • 0034646213 scopus 로고    scopus 로고
    • Rat strain-specific actions of 17 beta-estradiol in the mammary gland: correlation between estrogen-induced lobuloalveolar hyperplasia and susceptibility to estrogen-induced mammary cancers
    • Harvell D.M., Strecker T.E., Tochacek M., Xie B., Pennington K.L., McComb R.D., Roy S.K., and Shull J.D. Rat strain-specific actions of 17 beta-estradiol in the mammary gland: correlation between estrogen-induced lobuloalveolar hyperplasia and susceptibility to estrogen-induced mammary cancers. Proc. Natl. Acad. Sci. U.S.A. 97 (2000) 2779-2784
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 2779-2784
    • Harvell, D.M.1    Strecker, T.E.2    Tochacek, M.3    Xie, B.4    Pennington, K.L.5    McComb, R.D.6    Roy, S.K.7    Shull, J.D.8
  • 7
    • 0013854955 scopus 로고
    • Nature of the hepatomegalic effect produced by ethyl-chlorophenoxy-isobutyrate in the rat
    • Hess R., Staubli W., and Riess W. Nature of the hepatomegalic effect produced by ethyl-chlorophenoxy-isobutyrate in the rat. Nature 208 (1965) 856-858
    • (1965) Nature , vol.208 , pp. 856-858
    • Hess, R.1    Staubli, W.2    Riess, W.3
  • 9
    • 0021885634 scopus 로고
    • The clearance and metabolism of estradiol-17 esters in the rat
    • Larner J.M., and Hochberg R.B. The clearance and metabolism of estradiol-17 esters in the rat. Endocrinology 117 (1985) 1209-1214
    • (1985) Endocrinology , vol.117 , pp. 1209-1214
    • Larner, J.M.1    Hochberg, R.B.2
  • 11
    • 11144221653 scopus 로고    scopus 로고
    • Prevention of solely estrogen-induced mammary tumors by Tamoxifen: evidence for estrogen receptor mediation
    • Li S.A., Weroha S.J., Tawfik O., and Li J.J. Prevention of solely estrogen-induced mammary tumors by Tamoxifen: evidence for estrogen receptor mediation. J. Endocrinol. 175 2 (2002) 297-305
    • (2002) J. Endocrinol. , vol.175 , Issue.2 , pp. 297-305
    • Li, S.A.1    Weroha, S.J.2    Tawfik, O.3    Li, J.J.4
  • 12
    • 33645890289 scopus 로고    scopus 로고
    • Phenobarbital treatment inhibits the formation of estradiol-dependent mammary tumors in the August-Copenhagen Irish rat
    • Mesia-Vela S., Sanchez R.I., Reuhl K.R., Conney A.H., and Kauffman F.C. Phenobarbital treatment inhibits the formation of estradiol-dependent mammary tumors in the August-Copenhagen Irish rat. J. Pharmacol. Exp. Ther. 317 2 (2006) 590-597
    • (2006) J. Pharmacol. Exp. Ther. , vol.317 , Issue.2 , pp. 590-597
    • Mesia-Vela, S.1    Sanchez, R.I.2    Reuhl, K.R.3    Conney, A.H.4    Kauffman, F.C.5
  • 13
    • 2942729478 scopus 로고    scopus 로고
    • Dietary clofibrate inhibits induction of hepatic antioxidant enzymes by chronic estradiol in female ACI rats
    • Mesia-Vela S., Sanchez R.I., Reuhl K.R., Conney A.H., and Kauffman F.C. Dietary clofibrate inhibits induction of hepatic antioxidant enzymes by chronic estradiol in female ACI rats. Toxicology 200 2/3 (2004) 103-111
    • (2004) Toxicology , vol.200 , Issue.2-3 , pp. 103-111
    • Mesia-Vela, S.1    Sanchez, R.I.2    Reuhl, K.R.3    Conney, A.H.4    Kauffman, F.C.5
  • 14
    • 0036045456 scopus 로고    scopus 로고
    • Catechol estrogen formation in liver microsomes from female ACI and Sprague-Dawley rats: comparison of 2- and 4-hydroxylation revisited
    • Mesia-Vela S., Sanchez R.I., Li J.J., Li S.A., Conney A.H., and Kauffman F.C. Catechol estrogen formation in liver microsomes from female ACI and Sprague-Dawley rats: comparison of 2- and 4-hydroxylation revisited. Carcinogenesis 23 8 (2002) 1369-1372
    • (2002) Carcinogenesis , vol.23 , Issue.8 , pp. 1369-1372
    • Mesia-Vela, S.1    Sanchez, R.I.2    Li, J.J.3    Li, S.A.4    Conney, A.H.5    Kauffman, F.C.6
  • 16
    • 40249094699 scopus 로고    scopus 로고
    • Protective roles of quinone reductase and tamoxifen against estrogen-induced mammary tumorigenesis
    • Montano M.M., Chaplin L.J., Deng H., Mesia-Vela S., Gaikwad N., Zahid M., and Rogan E. Protective roles of quinone reductase and tamoxifen against estrogen-induced mammary tumorigenesis. Oncogene (2006) 1-4
    • (2006) Oncogene , pp. 1-4
    • Montano, M.M.1    Chaplin, L.J.2    Deng, H.3    Mesia-Vela, S.4    Gaikwad, N.5    Zahid, M.6    Rogan, E.7
  • 17
    • 0031864194 scopus 로고    scopus 로고
    • Effect of the peroxisome proliferator ciprofibrate on lipid peroxidation and 8-hydroxydeoxyguanosine formation in transgenic mice with elevated hepatic catalase activity
    • Nilakantan V., Apear B.T., and Glauert H.P. Effect of the peroxisome proliferator ciprofibrate on lipid peroxidation and 8-hydroxydeoxyguanosine formation in transgenic mice with elevated hepatic catalase activity. Free Radic. Biol. Med. 24 9 (1998) 1430-1436
    • (1998) Free Radic. Biol. Med. , vol.24 , Issue.9 , pp. 1430-1436
    • Nilakantan, V.1    Apear, B.T.2    Glauert, H.P.3
  • 18
    • 0035068679 scopus 로고    scopus 로고
    • Effects of peroxisome proliferators on antioxidant enzymes and antioxidant vitamins in rats and hamsters
    • O'Brien M.L., Twaroski T.P., Cunningham M.L., Glauert H.P., and Spear B.T. Effects of peroxisome proliferators on antioxidant enzymes and antioxidant vitamins in rats and hamsters. Toxicol. Sci. 60 (2001) 271-278
    • (2001) Toxicol. Sci. , vol.60 , pp. 271-278
    • O'Brien, M.L.1    Twaroski, T.P.2    Cunningham, M.L.3    Glauert, H.P.4    Spear, B.T.5
  • 19
    • 0035451601 scopus 로고    scopus 로고
    • Mechanism of clofibrate hepatotoxicity: mitochondrial damage and oxidative stress in hepatocytes
    • Qu B., Li O.T., Wong K.P., Tan T.M., and Halliwell B. Mechanism of clofibrate hepatotoxicity: mitochondrial damage and oxidative stress in hepatocytes. Free Radic. Biol. Med. 31 5 (2001) 659-669
    • (2001) Free Radic. Biol. Med. , vol.31 , Issue.5 , pp. 659-669
    • Qu, B.1    Li, O.T.2    Wong, K.P.3    Tan, T.M.4    Halliwell, B.5
  • 20
    • 0030478960 scopus 로고    scopus 로고
    • Hepatocarcinogenesis of peroxisome proliferators
    • Rao M.S., and Reddy J.K. Hepatocarcinogenesis of peroxisome proliferators. Ann. N.Y. Acad. Sci. 804 (1996) 573-587
    • (1996) Ann. N.Y. Acad. Sci. , vol.804 , pp. 573-587
    • Rao, M.S.1    Reddy, J.K.2
  • 21
    • 0021051308 scopus 로고
    • Carcinogenesis by hepatic peroxisome proliferators, evaluation of the risk of hypolipidemic drugs and industrial plasticizers to humans
    • Reddy J.K., and Lalwai N.D. Carcinogenesis by hepatic peroxisome proliferators, evaluation of the risk of hypolipidemic drugs and industrial plasticizers to humans. Crit. Rev. Toxicol. 12 (1983) 1-58
    • (1983) Crit. Rev. Toxicol. , vol.12 , pp. 1-58
    • Reddy, J.K.1    Lalwai, N.D.2
  • 22
    • 0018888058 scopus 로고
    • Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens
    • Reddy J.K., Azarnoff D.L., and Hignite C.E. Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens. Nature 283 (1980) 397-398
    • (1980) Nature , vol.283 , pp. 397-398
    • Reddy, J.K.1    Azarnoff, D.L.2    Hignite, C.E.3
  • 23
    • 0347480514 scopus 로고    scopus 로고
    • Induction of NADP(H) quinone oxidoreductase and glutathione S-transferase activities in livers of female August-Copenhagen Irish rats treated chronically with estradiol: comparison with the Sprague-Dawley rat
    • Sanchez R.I., Mesia-Vela S., and Kauffman F.C. Induction of NADP(H) quinone oxidoreductase and glutathione S-transferase activities in livers of female August-Copenhagen Irish rats treated chronically with estradiol: comparison with the Sprague-Dawley rat. J. Steroid Biochem. Mol. Biol. 87 2-3 (2003) 199-206
    • (2003) J. Steroid Biochem. Mol. Biol. , vol.87 , Issue.2-3 , pp. 199-206
    • Sanchez, R.I.1    Mesia-Vela, S.2    Kauffman, F.C.3
  • 24
    • 0032875359 scopus 로고    scopus 로고
    • Antitumor effects of bis(ethyl)polyamine analogs on mammary tumor development in FVB/NTgN (MMTVneu) transgenic mice
    • Shah N., Antony T., Haddad S., Amenta P., Shirahata A., Thomas T.J., and Thomas T. Antitumor effects of bis(ethyl)polyamine analogs on mammary tumor development in FVB/NTgN (MMTVneu) transgenic mice. Cancer Lett. 146 1 (1999) 15-23
    • (1999) Cancer Lett. , vol.146 , Issue.1 , pp. 15-23
    • Shah, N.1    Antony, T.2    Haddad, S.3    Amenta, P.4    Shirahata, A.5    Thomas, T.J.6    Thomas, T.7
  • 25
    • 0031419014 scopus 로고    scopus 로고
    • Ovary-intact, but not ovarectomized female ACI rats treated with 17b-estradiol develop mammary carcinomas
    • Shull J.D., Spady T.J., Snyder M.C., Johansson S.L., and Pennington K.L. Ovary-intact, but not ovarectomized female ACI rats treated with 17b-estradiol develop mammary carcinomas. Carcinogenesis 15 8 (1997) 1595-1601
    • (1997) Carcinogenesis , vol.15 , Issue.8 , pp. 1595-1601
    • Shull, J.D.1    Spady, T.J.2    Snyder, M.C.3    Johansson, S.L.4    Pennington, K.L.5
  • 26
    • 0033279004 scopus 로고    scopus 로고
    • Genetic bases of estrogen-induced pituitary growth in an intercross between the ACI and Copenhagen rat strains: dominant mendelian inheritance of the ACI phenotype
    • Spady T.J., Pennington K.L., McComb R.D., and Shull J.D. Genetic bases of estrogen-induced pituitary growth in an intercross between the ACI and Copenhagen rat strains: dominant mendelian inheritance of the ACI phenotype. Endocrinology 140 6 (1999) 2828-2835
    • (1999) Endocrinology , vol.140 , Issue.6 , pp. 2828-2835
    • Spady, T.J.1    Pennington, K.L.2    McComb, R.D.3    Shull, J.D.4
  • 27
    • 0018756733 scopus 로고
    • Neoplastic responses and correlated plasma prolactin levels in diethylstilbestrol-treated ACI and Spraque-Dawley rats
    • Stone J.P., Holtzman S., and Shellabarger C.J. Neoplastic responses and correlated plasma prolactin levels in diethylstilbestrol-treated ACI and Spraque-Dawley rats. Cancer Res. 39 (1979) 773-778
    • (1979) Cancer Res. , vol.39 , pp. 773-778
    • Stone, J.P.1    Holtzman, S.2    Shellabarger, C.J.3
  • 28
    • 0028859196 scopus 로고
    • High-performance liquid chromatography separation of hydroxylated estradiol metabolites: formation of estradiol metabolites by liver microsomes from male and female rats
    • Suchar L.A., Chang R.L., Rosen R.T., Lech J., and Conney A.H. High-performance liquid chromatography separation of hydroxylated estradiol metabolites: formation of estradiol metabolites by liver microsomes from male and female rats. J. Pharmacol. Exp. Ther. 272 (1995) 197-206
    • (1995) J. Pharmacol. Exp. Ther. , vol.272 , pp. 197-206
    • Suchar, L.A.1    Chang, R.L.2    Rosen, R.T.3    Lech, J.4    Conney, A.H.5
  • 29
    • 23844476731 scopus 로고    scopus 로고
    • A fascination with enzymes: the journey not the arrival matters
    • Talalay P. A fascination with enzymes: the journey not the arrival matters. J. Biol. Chem. 280 (2005) 28829-28847
    • (2005) J. Biol. Chem. , vol.280 , pp. 28829-28847
    • Talalay, P.1
  • 30
    • 0020628133 scopus 로고
    • Induction of two immunochemically related rat liver cytochrome P450 isozymes cytochromes P450c and P450d, by structurally diverse xenobiotics
    • Thomas P.E., Reick L.M., Ryan D.E., and Levin W. Induction of two immunochemically related rat liver cytochrome P450 isozymes cytochromes P450c and P450d, by structurally diverse xenobiotics. J. Biol. Chem. 258 (1983) 4590-4598
    • (1983) J. Biol. Chem. , vol.258 , pp. 4590-4598
    • Thomas, P.E.1    Reick, L.M.2    Ryan, D.E.3    Levin, W.4
  • 31
    • 19944428679 scopus 로고    scopus 로고
    • The effects of steroidal estrogens in ACI rat mammary carcinogenesis: 17beta-estradiol, 2-hydroxyestradiol, 4-hydroxyestradiol, 16alpha-hydroxyestradiol, and 4-hydroxyestrone
    • Turan V.K., Sanchez R.I., Li J.J., Li S.A., Reuhl K.R., Thomas P.E., Conney A.H., Gallo M.A., Kauffman F.C., and Mesia-Vela S. The effects of steroidal estrogens in ACI rat mammary carcinogenesis: 17beta-estradiol, 2-hydroxyestradiol, 4-hydroxyestradiol, 16alpha-hydroxyestradiol, and 4-hydroxyestrone. J. Endocrinol. 183 1 (2004) 91-99
    • (2004) J. Endocrinol. , vol.183 , Issue.1 , pp. 91-99
    • Turan, V.K.1    Sanchez, R.I.2    Li, J.J.3    Li, S.A.4    Reuhl, K.R.5    Thomas, P.E.6    Conney, A.H.7    Gallo, M.A.8    Kauffman, F.C.9    Mesia-Vela, S.10
  • 32
    • 0036496561 scopus 로고    scopus 로고
    • Effect of clofibrate administration on the esterification and deesterification of steroid hormones by liver and extrahepatic tissues in rats
    • Xu S., Zhu B.T., and Conney A.H. Effect of clofibrate administration on the esterification and deesterification of steroid hormones by liver and extrahepatic tissues in rats. Biochem. Pharmacol. 63 5 (2002) 985-992
    • (2002) Biochem. Pharmacol. , vol.63 , Issue.5 , pp. 985-992
    • Xu, S.1    Zhu, B.T.2    Conney, A.H.3
  • 33
    • 85047684866 scopus 로고    scopus 로고
    • PPARalpha-dependent induction of liver microsomal esterification of estradiol and testosterone by a prototypical peroxisome proliferator
    • Xu S., Zhu B.T., Turan V., Rusyn I., Thurman R., Peters J.M., Gonzalez F.J., and Conney A.H. PPARalpha-dependent induction of liver microsomal esterification of estradiol and testosterone by a prototypical peroxisome proliferator. Endocrinology 142 8 (2001) 3554-3557
    • (2001) Endocrinology , vol.142 , Issue.8 , pp. 3554-3557
    • Xu, S.1    Zhu, B.T.2    Turan, V.3    Rusyn, I.4    Thurman, R.5    Peters, J.M.6    Gonzalez, F.J.7    Conney, A.H.8
  • 34
    • 0035197415 scopus 로고    scopus 로고
    • Stimulatory effect of clofibrate and gemfibrozil administration on the formation of fatty acid esters of estradiol by rat liver microsomes
    • Xu S., Zhu B.T., and Conney A.H. Stimulatory effect of clofibrate and gemfibrozil administration on the formation of fatty acid esters of estradiol by rat liver microsomes. J. Pharmacol. Exp. Ther. 296 (2001) 188-197
    • (2001) J. Pharmacol. Exp. Ther. , vol.296 , pp. 188-197
    • Xu, S.1    Zhu, B.T.2    Conney, A.H.3
  • 35
    • 0035082605 scopus 로고    scopus 로고
    • Stimulatory effect of clofibrate on the action of estradiol in the mammary gland but not in the uterus of rats
    • Xu S., Zhu B.T., Cai M.X., and Conney A.H. Stimulatory effect of clofibrate on the action of estradiol in the mammary gland but not in the uterus of rats. J. Pharmacol. Exp. Ther. 297 1 (2001) 50-56
    • (2001) J. Pharmacol. Exp. Ther. , vol.297 , Issue.1 , pp. 50-56
    • Xu, S.1    Zhu, B.T.2    Cai, M.X.3    Conney, A.H.4
  • 36
    • 0034678013 scopus 로고    scopus 로고
    • Hydrogen peroxide generation in peroxisome proliferator-induced oncogenesis
    • Yeldandi A.V., Rao M.S., and Reddy J.K. Hydrogen peroxide generation in peroxisome proliferator-induced oncogenesis. Mutat. Res. 448 2 (2000) 159-177
    • (2000) Mutat. Res. , vol.448 , Issue.2 , pp. 159-177
    • Yeldandi, A.V.1    Rao, M.S.2    Reddy, J.K.3
  • 37
    • 0028203252 scopus 로고
    • Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates
    • Zhang Y., Kensler T.W., Cho C.G., Posner G.H., and Talalay P. Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates. Proc. Natl. Acad. Sci U.S.A. 91 (1994) 3147-3150
    • (1994) Proc. Natl. Acad. Sci U.S.A. , vol.91 , pp. 3147-3150
    • Zhang, Y.1    Kensler, T.W.2    Cho, C.G.3    Posner, G.H.4    Talalay, P.5


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