The RecQ DNA helicases: Jacks-of-all-trades or master-tradesmen?

Cell Research

Volumn 18, Issue 3, 2008, Pages 328-330

  Hunter, Neil ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RECQ HELICASE;

ANIMAL; ARTICLE; DNA REPAIR; DNA REPLICATION; DOUBLE STRANDED DNA BREAK; GENETIC RECOMBINATION; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY;

ANIMALS; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA REPLICATION; HUMANS; RECOMBINATION, GENETIC; RECQ HELICASES;

CARANGIDAE;

EID: 40249111551     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2008.33     Document Type: Article

References (15)

1. Hanada K, Hickson ID. Molecular genetics of RecQ helicase disorders. Cell Mol Life Sci 2007; 64:2306-2322.
2. Sharma S, Doherty KM, Brosh RM Jr. Mechanisms of RecQ helicases in pathways of DNAmetabolism and maintenance of genomic stability. Biochem J 2006; 398:319-337.
3. Wu L, Bachrati CZ, Ou J, et al. BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates. Proc Natl Acad Sci USA 2006; 103:4068-4073.
4. Raynard S, Bussen W, Sung P. A double Holliday junction dissolvasome comprising BLM, topoisomerase IIIalpha, and BLAP75. J Biol Chem 2006; 281:13861-13864.
5. Sangrithi MN, Bernal JA, Madine M, et al. Initiation of DNA replication requires the RECQL4 protein mutated in Rothmund-Thomson syndrome. Cell 2005; 121:887-898.
6. Park SJ, Lee YJ, Beck BD, Lee SH. A positive involvement of RecQL4 in UV-induced S-phase arrest. DNA Cell Biol 2006; 25:696-703.
7. Cobb JA, Bjergbaek L, Shimada K, Frei C, Gasser SM. DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1. EMBO J 2003; 22:4325-4336.
8. Sharma S, Brosh RM. Human RECQ1 is a DNA damage responsive protein required for genotoxic stress resistance and suppression of sister chromatid exchanges. PLoS ONE 2007; 2:e1297.
9. Spell RM, Jinks-Robertson S. Examination of the roles of Sgs1 and Srs2 helicases in the enforcement of recombination fidelity in Saccharomyces cerevisiae. Genetics 2004; 168:1855-1865.
10. Hu Y, Lu X, Barnes E, et al. Recql5 and Blm RecQ DNA helicases have nonredundant roles in suppressing crossovers. Mol Cell Biol 2005; 25:3431-3442.
11. Hu Y, Raynard S, Sehorn MG, et al. RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments. Genes Dev 2007; 21:3073-3084.
12. Branzei D, Foiani M. RecQ helicases queuing with Srs2 to disrupt Rad51 filaments and suppress recombination. Genes Dev 2007; 21:3019-3026.
13. Kohzaki M, Hatanaka A, Sonoda E, et al. Cooperative roles of vertebrate Fbh1 and Blm DNA helicases in avoidance of crossovers during recombination initiated by replication fork collapse. Mol Cell Biol 2007; 27:2812-2820.
14. Veaute X, Jeusset J, Soustelle C, et al. The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments. Nature 2003; 423:309-312.
15. Bugreev DV, Yu X, Egelman EH, Mazin AV. Novel pro- and anti-recombination activities of the Bloom's syndrome helicase. Genes Dev 2007; 21:3085-3094.